Photo by JG Morris

Plan, book, travel with confidence
Better together
Save up to NT$25,000 when you book a flight and hotel together*
Find the right fit
With over 300,000 hotels worldwide, it's easy to create a perfect package
Rest easy
Plan, book, and manage your trip all in one place

Top Pet-friendly Southeast Missouri Hotels

Motel 6 Poplar Bluff, MO

4101 Highway 67 N Poplar Bluff MO

2 hours drive from Johnson's Shut-ins State Park

Stay at this motel in Poplar Bluff. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...

8/10 Very Good! (1,001 reviews)

"The motel was great, however, they did not have blankets for the beds and the shower head left a lot to be desired. We would stay here again."

Reviewed on 2026/6/15

Microtel Inn & Suites by Wyndham Sainte Genevieve

21958 Hwy 32 Ste Genevieve MO

3 hours drive from Johnson's Shut-ins State Park

Book a stay at this business-friendly hotel in Ste Genevieve. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...

8.8/10 Excellent! (642 reviews)

"Ron was great; only questionable area was the carpet - clearly very old and it was quite dingy in appearance. That said, the beds are great and clean, room was well “freshened up”…. Great nights rest for the two nights we stayed. Will gladly stay here again during our next trip to the beautiful Ste ..."

Reviewed on 2026/6/21

La Quinta Inn & Suites by Wyndham Festus - St. Louis South

1001 Veterans Blvd Festus MO

2 hours drive from Johnson's Shut-ins State Park

This hotel is pet-friendly, allowing dogs and cats with an additional fee. If you're going for a walk during your stay, swing by nearby Jorkerst Memorial ...

8/10 Very Good! (1,003 reviews)

"Not once in my 3 day stay did anyone come in and clean the room."

Reviewed on 2026/6/19

See all 661 properties in Southeast Missouri

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.