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Top Pet-friendly South Carolina Midlands Hotels

La Quinta Inn & Suites by Wyndham Florence

2123 W Lucas St Florence SC

3 hours drive from Fort Jackson

This pet-friendly hotel welcomes dogs and cats (fees apply).

7.8/10 Good! (1,593 reviews)

"The front desk staff was very helpful and polite. The room was clean and the bed was very comfortable. Breakfast was okay. My only real complaint was the hotel was noisy, alot of door slamming and loud talking all night."

Reviewed on 2026/6/9

La Quinta Inn by Wyndham Columbia SE / Fort Jackson

7333 Garners Ferry Rd Columbia SC

9 min drive from Fort Jackson

This pet-friendly hotel welcomes dogs and cats (fees apply).

8/10 Very Good! (1,019 reviews)

"Decent hotel. Clean rooms. Located right off the highway. Plenty of food and shopping options nearby."

Reviewed on 2026/6/8

Hampton Inn Columbia I-26/Harbison Blvd.

101 Woodcross Dr Columbia SC

31 min drive from Fort Jackson

Hiking and biking trails are ready for you to explore near this lakefront hotel, where dogs and cats can stay for an additional fee.

9.2/10 Wonderful! (1,009 reviews)

"All was well. No issues, would recommend to others as a nice, clean, quite place."

Reviewed on 2026/6/8

See all 3,275 properties in South Carolina Midlands

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.