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Top Pet-friendly South Carolina Midlands Hotels

La Quinta Inn & Suites by Wyndham Florence

2123 W Lucas St Florence SC

3 hours drive from Fort Jackson

This pet-friendly hotel welcomes dogs and cats (fees apply).

7.8/10 Good! (1,673 reviews)

Good location, pet friendly

Reviewed on 2026/1/19

La Quinta Inn by Wyndham Columbia SE / Fort Jackson

7333 Garners Ferry Rd Columbia SC

9 min drive from Fort Jackson

This pet-friendly hotel welcomes dogs and cats (fees apply).

7.6/10 Good! (1,001 reviews)

Rooms updated excellent appearance. Room ac had some extra vibration sound to deal with and bat vent fan a little noisy needed to be tightened up. Food good coffee and hot water not enough closer to warm. Arrival erson was more friendly and pleasant compared to check out person. Overall very impressed ...

Reviewed on 2026/1/13

Hampton Inn Columbia I-26/Harbison Blvd.

101 Woodcross Dr Columbia SC

31 min drive from Fort Jackson

Hiking and biking trails are ready for you to explore near this lakefront hotel, where dogs and cats can stay for an additional fee.

9/10 Wonderful! (1,002 reviews)

I was totally impressed buy the service I received from Alexa. Once we checked in the texted us to make sure everything thing was ok and asked if there was anything she could do to improve our experience The room was clean. The bed was so comfortable. I highly recommend this location. The Hampton ...

Reviewed on 2026/1/9

See all 3,139 properties in South Carolina Midlands

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.