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Top Pet-friendly South Carolina Midlands Hotels

La Quinta Inn & Suites by Wyndham Florence

2123 W Lucas St Florence SC

3 hours drive from Fort Jackson

This pet-friendly hotel welcomes dogs and cats (fees apply).

7.8/10 Good! (1,597 reviews)

"easy access"

Reviewed on 2026/6/14

La Quinta Inn by Wyndham Columbia SE / Fort Jackson

7333 Garners Ferry Rd Columbia SC

9 min drive from Fort Jackson

This pet-friendly hotel welcomes dogs and cats (fees apply).

8/10 Very Good! (1,041 reviews)

"They are remodeling on the first floor but it won’t affect your stay. The pool area is clean and well maintained. Enjoyed my stay would stay again"

Reviewed on 2026/6/17

Hampton Inn Columbia I-26/Harbison Blvd.

101 Woodcross Dr Columbia SC

31 min drive from Fort Jackson

Hiking and biking trails are ready for you to explore near this lakefront hotel, where dogs and cats can stay for an additional fee.

9.2/10 Wonderful! (1,016 reviews)

"What was disappointing was my experience with Expedia where I booked my stay. When I booked my room for two night I purchased a protection plan in case plans changed which they did. On first day ,June 6th ,after checking in I alerted hotel that we needed to return home early and would not be staying ..."

Reviewed on 2026/6/17

See all 3,281 properties in South Carolina Midlands

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.