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Top Pet-friendly South Carolina Midlands Hotels

La Quinta Inn & Suites by Wyndham Florence

2123 W Lucas St Florence SC

3 hours drive from Fort Jackson

This pet-friendly hotel welcomes dogs and cats (fees apply).

7.8/10 Good! (1,562 reviews)

"Front desk was really nice and friendly. The King room was not ready so we were assigned two Queen beds room ... not what we really wanted. Pool was nice but did not open until 5pm. Room was mostly clean but we only had ONE serving of coffee in the morning. In addition, the slide in piece for coffee ..."

Reviewed on 2026/7/5

La Quinta Inn by Wyndham Columbia SE / Fort Jackson

7333 Garners Ferry Rd Columbia SC

9 min drive from Fort Jackson

This pet-friendly hotel welcomes dogs and cats (fees apply).

8.2/10 Very Good! (1,010 reviews)

"Great parking and breakfast"

Reviewed on 2026/7/4

Hampton Inn Columbia I-26/Harbison Blvd.

101 Woodcross Dr Columbia SC

31 min drive from Fort Jackson

Hiking and biking trails are ready for you to explore near this lakefront hotel, where dogs and cats can stay for an additional fee.

9.2/10 Wonderful! (1,004 reviews)

"Very nice hotel. Comfortable bed and clean room. Staff very courteous."

Reviewed on 2026/7/2

See all 3,295 properties in South Carolina Midlands

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.