Southeast Missouri Cheap Vacations 2026

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Top Cheap Southeast Missouri Hotels

Super 8 by Wyndham Farmington

930 Valley Creek Dr Farmington MO

2 hours drive from Mark Twain National Forest

Book a stay at this business-friendly motel in Farmington. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...

Motel 6 Poplar Bluff, MO

4101 Highway 67 N Poplar Bluff MO

3 hours drive from Mark Twain National Forest

Stay at this motel in Poplar Bluff. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...

8/10 Very Good! (1,001 reviews)

"Room was clean, parking was fine but limited with a lot of cars in lot"

Reviewed on 2026/10/24

Super 8 by Wyndham Pevely

1711 Highway Z Pevely MO

3 hours drive from Mark Twain National Forest

Book a stay at this business-friendly motel in Pevely. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Pevely Park and Sun Valley Park ...

See all 697 properties in Southeast Missouri

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.