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Top Cheap Eastern Piedmont Hotels

Red Roof Inn Durham - Duke Univ Medical Center

1915 N Pointe Drive Durham NC

5 min drive from Duke University

Stay at this hotel in Durham. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...

6.8/10 (1,001 reviews)

"We stay at this property pretty often.. Just wish the showers and the floors were a little bit cleaner.. but other than that it's a good place to stay.."

Reviewed on 2026/6/21

Deluxe Inn Fayetteville - I-95 Exit 49

2123 Cedar Creek Rd Fayetteville NC

3 hours drive from Duke University

Stay at this motel in Fayetteville. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...

9/10 Wonderful! (1,815 reviews)

"Clean and organized. A/C worked great. Friendly staff."

Reviewed on 2026/7/2

Royal Inn

3460 Hillsborough Rd Durham NC

28 min walk from Duke University

Book a stay at this golf hotel in Durham. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the clean rooms in our reviews. Popular attractions ...

See all 4,969 properties in Eastern Piedmont

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.