Photo by RebeccasRoutes

Plan, book, travel with confidence
Better together
Save up to NT$5,067 when you book a flight and hotel together*
Find the right fit
With over 300,000 hotels worldwide, it's easy to create a perfect package
Rest easy
Plan, book, and manage your trip all in one place

Top Adventure Santa Cruz Island Hotels

Angermeyer Waterfront Inn

Punta Estrada, Isla Santa Cruz, Puerto Ayora, Galapagos

14 min walk from Charles Darwin Research Station

Stay at this 3.5-star hotel in Puerto Ayora. Enjoy free breakfast, free WiFi, and a marina. Our guests praise the helpful staff in our reviews. Popular attractions ...

9.4/10 Exceptional! (122 reviews)

Enio is a great asset for this hotel. He was very helpful and friendly. The hotel itself is very quiet, clean and comfortable.

Reviewed on 2025/10/4

Ariana´S Galapagos Hostal

Avenida Galapagos #806 y Pasaje #2, Puerto Ayora

17 min walk from Charles Darwin Research Station

Stay at this 3-star B&B in Puerto Ayora. Enjoy free WiFi, free parking, and a rooftop terrace. Our guests praise the property condition in our reviews. Popular ...

8.6/10 Excellent! (55 reviews)

The manager spoke english. He was very friendly and helpful.

Reviewed on 2025/3/4

Maytenus Galapagos

Calle Petrel y Scalesia Puerto Ayora Santa Cruz

8 min walk from Charles Darwin Research Station

Stay at this aparthotel in Puerto Ayora. Enjoy free WiFi, breakfast (surcharge), and a 24-hour front desk. Popular attractions Fishing Piers and Charles Darwin ...

OLD FAR AWAY FROM EVERYTHING

Very far from Restaurants,stores and Main Street. OVERPRICED. OLD. Got a different apartment from the one booked. No taxi in town knows the place. Managed by old couple. Will not recommend it. The

Reviewed on 2019/5/15

See all 210 properties in Santa Cruz Island

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.