South America Vacations & Trips

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

    • payments icon

    Better together

    Save up to NT$5,067 when you book a flight and hotel together*
    lob hotels icon

    Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
    lob packages icon

    Rest easy

    Plan, book, and manage your trip all in one place

Top destinations in South America

Bank of Brazil Cultural Center showing heritage architecture and street scenes as well as a large group of people
FlightsFlightsHotelsHotels

Sao Paulo

Sao Paulo

South America Hotel Deals

Rochester Classic

Rochester Classic

3.5 out of 5
Esmeralda 542, Buenos Aires, Capital Federal
Fully refundableReserve now, pay when you stay
The price is NT$2,091 per night from Sep 1 to Sep 2
NT$2,091
NT$2,183 total
Sep 1 - Sep 2
Rochester Classic
Regal Pacific Buenos Aires

Regal Pacific Buenos Aires

4.5 out of 5
25 De Mayo, 764, Buenos Aires, Capital Federal
Fully refundableReserve now, pay when you stay
Get rates
Regal Pacific Buenos Aires
Concorde Hotel

Concorde Hotel

3 out of 5
25 De Mayo 630, Buenos Aires, Capital Federal
Get rates
Concorde Hotel
See all 115,153 properties in South America
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

Can I travel to South America right now?
Find info about South America travel restrictions, quarantine policies and much more by going to our Covid-19 Travel Advisor.
If I'm not able to travel, can I cancel my South America vacation package?
Don't stress if you're rethinking your South America vacation package — you can cancel or amend your booking. And if you've booked it within 24 hours, you may be able to do it for free. However, bookings made more than 24 hours ago may incur a fee from your hotel, airline or car rental company. We totally understand life can throw the occasional spanner in the works, so look up our Customer Service Portal if that occurs. When you're ready to make changes, we'll be here to help.
When is the best time of year to visit South America?
Anytime is an excellent time of the year to take a break in South America, but generally you'll land the best deals in . Prices increase in , so expect to pay more for your flights and hotel. Love sightseeing but don't like lining up for attractions? Organize your South America escape for . Typically, it's a lot quieter than in .
What should I do on vacation in South America?
From exciting attractions to hidden treasures, there's lots to do in South America. To help you plan your time in this amazing location, here are some of the most sought-after tours and activities:


How far in advance should I book my South America vacation?
While not all airlines advertise tickets early, it's usually possible to start comparing international fares on Expedia up to 12 months in advance. This is the time when you'll bag some fantastic bargains. If you're booking late, there's a chance you could get lucky. Sometimes the lowest prices emerge only weeks before departure.
What should I know before booking a South America travel package?
A travel package can be more affordable than individually booking everything you need for your escape. For example, bundle your flights, hotels and rental cars and save a pretty penny. Whatever your vacation goals are, you'll find a package to suit your budget.

Discover the most popular places to visit in South America

Eurico Gaspar Dutra Stadium

Catch an event at Eurico Gaspar Dutra Stadium during your trip to Cuiabá. Amble around the area's riverfront or visit its cathedral.

Eurico Gaspar Dutra Stadium
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.