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Top Adults Only Florida Keys Hotels

The Southernmost Inn - Adults Only

525 United Street Key West FL

36 min drive from Florida Keys Beaches

Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and parking (surcharge). Our guests praise the breakfast and the pool in our reviews. ...

8.4/10 Very Good! (1,398 reviews)

"We were told we would have housecleaning every other day, we did not get it even one day. We had to keep going to the desk to get new towels, toilet paper soap. We even hung the sign on the door stating that we wanted it cleaned, and it was never cleaned. They messed up our parking and when we returned ..."

Reviewed on 2026/7/3

Paradise Inn Key West - Adults Only

819 Simonton Street Key West FL

36 min drive from Florida Keys Beaches

Book a stay at this business-friendly hotel in Key West. Enjoy free breakfast, parking (surcharge), and a garden. Our guests praise the breakfast and the pool ...

9.2/10 Wonderful! (1,000 reviews)

"Great boutique hotel close to every thing. Very impressed with the king suite it was so large and overlooked the pool. Nicely updated. Air conditioning was ice cold worked very well. Great happy hour with wine cheese and crackers. The girl at the front office goes out of her way to make sure you ..."

Reviewed on 2026/7/1

Heron House - Adult Only

512 Simonton St Key West FL

36 min drive from Florida Keys Beaches

Stay at this B&B in Key West. Enjoy free breakfast, free WiFi, and a rooftop terrace. Our guests praise the breakfast and the pool in our reviews. Popular attractions ...

9.2/10 Wonderful! (1,157 reviews)

"AMAZING place. Super well taken care of, roo.s are spacious and beautiful A(I stayed in room 10). The staff was super helpful and Greg was a Great. Just a few blocks from the Walgreens on Duval but way from all the craziness. Adults only makes a difference for sure! Will definetly return"

Reviewed on 2026/6/29

See all 8,312 properties in Florida Keys

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.