
Florida Keys Adults Only Vacations
Book a Adults Only Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to NT$5,067 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
Top Adults Only Florida Keys Hotels

The Southernmost Inn - Adults Only
525 United Street Key West FL
Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and parking (surcharge). Our guests praise the breakfast and the pool in our reviews. ...
8.2/10 Very Good! (1,246 reviews)
Property needs some serious maintenance. One guest cut their foot on a broken tile in the hot tub. They are working on painting the outside but let it go a little longer than they should have. The rooms shown on Expedia make them look much larger than they actually are. Bathroom was exceptionally ...
Reviewed on 2026/1/16

Paradise Inn Key West - Adults Only
819 Simonton Street Key West FL
Book a stay at this business-friendly hotel in Key West. Enjoy free breakfast, parking (surcharge), and daily housekeeping. Our guests praise the breakfast and ...
9/10 Wonderful! (1,004 reviews)
Great stay at the Paradise Inn. The staff was friendly and helpful, rooms are updated and clean with lots of space.
Reviewed on 2026/1/13

Heron House - Adult Only
512 Simonton St Key West FL
Stay at this B&B in Key West. Enjoy free breakfast, free WiFi, and a rooftop terrace. Our guests praise the breakfast and the pool in our reviews. Popular attractions ...
9/10 Wonderful! (1,146 reviews)
Fantastic find! Spacious clean room close to everything we wanted to see
Reviewed on 2026/1/13
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
