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Top Adults Only Florida Keys Hotels

The Southernmost Inn - Adults Only

525 United Street Key West FL

9 min walk from Duval Street

Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and parking (surcharge). Our guests praise the breakfast and the pool in our reviews. ...

8.2/10 Very Good! (1,285 reviews)

Tanesha at the feont desk was absolutley increbible. I stayes in quite a few places in Key West and this was by fae my favorite. But a huge shour out to her for being so kind and patient. Amazing experience!!!

Reviewed on 2026/3/28

Paradise Inn Key West - Adults Only

819 Simonton Street Key West FL

4 min walk from Duval Street

Book a stay at this business-friendly hotel in Key West. Enjoy free breakfast, parking (surcharge), and daily housekeeping. Our guests praise the breakfast and ...

9.2/10 Wonderful! (1,001 reviews)

Wonderful property. Great location. Feels quiet and secluded. We loved the breakfast and the happy hour.

Reviewed on 2026/3/28

Heron House - Adult Only

512 Simonton St Key West FL

3 min walk from Duval Street

Stay at this B&B in Key West. Enjoy free breakfast, free WiFi, and a rooftop terrace. Our guests praise the breakfast and the pool in our reviews. Popular attractions ...

9/10 Wonderful! (1,127 reviews)

Breakfast was very good. Staff was excellent and quick to help with anything we needed. Property and room both needed maintenance. Bed wasn’t comfortably.

Reviewed on 2026/3/27

See all 8,317 properties in Florida Keys

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.