Florida Keys Adults Only Vacations 2026

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Top Adults Only Florida Keys Hotels

The Southernmost Inn - Adults Only

525 United Street Key West FL

9 min walk from Duval Street

Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and parking (surcharge). Our guests praise the breakfast and the pool in our reviews. ...

8.4/10 Very Good! (1,445 reviews)

"Very close to all the action"

Reviewed on 2026/10/2

Paradise Inn Key West - Adults Only

819 Simonton Street Key West FL

4 min walk from Duval Street

Book a stay at this business-friendly hotel in Key West. Enjoy free breakfast, parking (surcharge), and a garden. Our guests praise the breakfast and the pool ...

9.2/10 Wonderful! (1,000 reviews)

"Very cute and clean property. The only thing I didn’t like was the fee for parking our rented golf cart in property."

Reviewed on 2026/9/30

Heron House - Adult Only

512 Simonton St Key West FL

3 min walk from Duval Street

Stay at this B&B in Key West. Enjoy free breakfast, free WiFi, and a rooftop terrace. Our guests praise the breakfast and the pool in our reviews. Popular attractions ...

9.2/10 Wonderful! (1,136 reviews)

"I’ve been to Key West many times, the Heron House is by far the best property we have stayed at. Perfect location to walk to Duval, Mallory Square. Great pool, friendly staff."

Reviewed on 2026/9/30

See all 8,253 properties in Florida Keys

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.