Penrose, MO
St. Louis
Popular places to visit
St. Louis Union Station
You can learn about the local history of St. Louis when you make a stop at a well-known site like St. Louis Union Station. Experience the area's great live music or attend a baseball game.
Busch Stadium
Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's acclaimed theater scene or attend a baseball game.
Gateway Arch
Enjoy 360-degree views and learn about the history of St. Louis at this world-famous landmark.
Enterprise Center
Catch an event at Enterprise Center during your trip to St. Louis. Experience the area's great live music or attend a baseball game.
St. Louis Zoo
In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world.
Forest Park
Nature, history and cultural institutions come together in one of the United States’ largest urban parks, which buzzes with St. Louis’ dynamic community spirit.
Penrose Hotel Deals
Drury Plaza Hotel St. Louis at the Arch
Great location and breakfast
Reviewed on 2026/3/21
Pear Tree Inn St. Louis Near Union Station
Good breakfast
Reviewed on 2026/3/21
Clayton Plaza Hotel & Extended Stay
Staff was very nice and responsive but property is extremely run down, old and in need of renovation. No pool on-site, no nearby restaurants and too far from downtown St. Louis
Reviewed on 2026/3/22
21C Museum Hotel St Louis
Traveled with a toddler and met our needs. Had a king room and liked it had a big storage closet so our stuff wasn’t all over the room. Only complaints was the fridge was small and there wasn’t an ice machine. I was able to go down to the desk and they got some from the restaurant but I needed more ...
Reviewed on 2026/3/21
Hollywood Casino & Hotel St. Louis
Great hotel for the hockey tournament... very nice staff... great location. The air quality was poor nearing the casino and awful inside... otherwise a great stay
Reviewed on 2026/3/21
Hyatt Regency St. Louis at The Arch
Hotel staff was amazing, except for check in folks, they gave us zero info. Ruth’s Chris Steakhouse was fantastic, as was Starbucks staff. Valet people were quick & super friendly. Hotel room was ok, bed was a little noisy from springs.
Reviewed on 2026/3/22
Other neighborhoods around Penrose
Central West End
Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.
Midtown
While you're in Midtown, take in top sights like Chaifetz Arena and jump on the metro at Grand Station to see more of the city.
The Grove
The Grove might not have many top sights, but St. Louis Science Center and Missouri Botanical Gardens and Arboretum are two attractions nearby that you can check out.
Downtown West
If you're spending some time in Downtown West, St. Louis Union Station and Enterprise Center are top sights worth seeing.
The Gate
While there might not be top attractions in The Gate, you can explore the larger area and discover places like St. Louis Union Station and Enterprise Center.
Lafayette Square
The restaurants and shopping are a few reasons travelers visit Lafayette Square. Though there aren't many top sights in the neighborhood, you can visit St. Louis Union Station and Enterprise Center, a few notable attractions nearby.
