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Find Resorts & Hotels with Spas in Southern Illinois, IL

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Check availability on Southern Illinois Resorts & Hotels with Spas

Tonight
Sep 29 - Sep 30
Tomorrow
Sep 30 - Oct 1
This weekend
Oct 2 - Oct 4
Next weekend
Oct 9 - Oct 11

Our top choices for Southern Illinois hotels with a spa

A modern spa room with a large hot tub, a glass wall with a reflective pattern, and a ceiling with a skylight.
A casino interior with slot machines, a large chandelier, and a carpeted floor.
A hotel lobby with a marble floor, a reception area with a '12 & VINE' sign, and a dining area with orange chairs and chandeliers.
A hotel lobby with a marble floor, a reception desk, a sign for 'Restrooms', and a large chandelier.

1. Walker's Bluff Casino Resort

Walker's Bluff Casino Resort
Carterville
  • Luxurious spa retreat with hot stone massages, sauna, and seasonal pools awaits at this casino resort with attentive staff and fine dining.
NT$5,429
NT$6,025 total
includes taxes & fees
Sep 30 - Oct 1
Walker's Bluff Casino Resort
A spacious lobby with a fireplace, comfortable seating, a staircase, and a large chandelier.
A hotel room with a bed, desk, chair, TV, and a small kitchenette area.
An indoor swimming pool with a clear view of the pool area, including the pool's edge, a set of stairs leading into the pool, and a few lounge chairs and tables around the pool.
A spacious hotel lobby with a high ceiling, a central seating area with sofas and chairs, a fireplace, and a television mounted on the wall.

2. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Cape Girardeau
  • Luxurious spa sanctuary awaits with full-service treatments and indoor pool in this centrally located hotel.
NT$3,146
NT$3,581 total
includes taxes & fees
Oct 29 - Oct 30
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
A couple relaxing by a window overlooking a bridge and water.
A bar area with a bartender, a bar counter with various bottles, and a view of the Gateway Arch.
A modern dining area with a long table set for a meal, large windows offering a view of a bridge, and a stone accent wall.
A room with large windows overlooking a bridge and water, featuring wooden chairs and a small table.

3. Four Seasons Hotel St Louis

Four Seasons Hotel St Louis
Downtown St. Louis
  • Discover a tranquil haven with 12 treatment rooms, outdoor pool, and breathtaking views at this rejuvenating spa retreat.
NT$11,918
NT$13,935 total
includes taxes & fees
Oct 4 - Oct 5
Four Seasons Hotel St Louis
A modern kitchen with wooden cabinets, a central island, and framed artwork on the walls.
An outdoor seating area with modern furniture, a bar, and large windows offering views of a cityscape.
A bar area with leather seating, a bar counter, and shelves of bottles.
A couple standing on a balcony with a cityscape view.

4. The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis
Clayton
  • Revel in a rejuvenating spa retreat with aromatherapy treatments and hot stone massages at this luxury St. Louis hotel.
NT$19,672
NT$22,965 total
includes taxes & fees
Oct 26 - Oct 27
The Ritz-Carlton, St. Louis
A reception desk with a wooden finish and the name "IDOL WOLF" on it.
A reception area with a curved wooden desk, a laptop, and a chair. The wall has a sign reading "Locust Street Athletic and Swim Club."
A multi-story building with a symmetrical facade, large windows, and a central entrance with a canopy.
A modern bathroom with a bathtub, a vanity with a mirror, and a shower area.

5. 21C Museum Hotel St Louis

21C Museum Hotel St Louis
Downtown West
  • Discover spa services, a steam room, and an Olympic-sized indoor pool at this modern hotel, all designed for rejuvenating getaways.
NT$4,562
NT$5,493 total
includes taxes & fees
Oct 22 - Oct 23
21C Museum Hotel St Louis
A modern spa with a curved reception desk, a large mirror, and a decorative water feature.
A bar area with multiple seating arrangements, a stage, and a chandelier.
A bakery display case with various pastries and cakes.
An indoor swimming pool with clear glass walls, metal railings, and a tiled floor.

6. Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
St. Charles
  • Riverside wellness oasis offers full-service spa with aromatherapy and hydrotherapy for a restorative retreat.
NT$4,743
NT$6,070 total
includes taxes & fees
Oct 13 - Oct 14
Ameristar Casino Resort and Spa
A two-story house with a front porch, a brick foundation, and a gabled roof.
A traditional interior with a wooden staircase, a desk with a computer, and a red chair.
A dining room with a round table set for six, surrounded by upholstered chairs. A vase with flowers and an American flag is on the table.
A kitchen with white cabinets, granite countertops, a stainless steel sink, a stove, and a microwave.

7. 1895 Washington Hotel

1895 Washington Hotel
Paducah
  • Unwind in a Victorian sanctuary with relaxing reflexology and soothing hydrotherapy treatments for total rejuvenation.
NT$2,145
NT$2,903 total
includes taxes & fees
Sep 30 - Oct 1
1895 Washington Hotel
A bathroom with a white sink, dark wooden door, and a shower area with striped glass walls.
A two-story building with a dark entrance, large windows, and a brick facade.
A room with a bed, a nightstand with a lamp, a painting on the wall, and a radiator.
A modern interior with a staircase, a large abstract painting, and a seating area with a glass coffee table.

8. Truitt Hotel

Truitt Hotel
Lafayette Square
NT$5,335
NT$6,476 total
includes taxes & fees
Oct 1 - Oct 2
Truitt Hotel
A dining area with a wooden table and chairs, a small Christmas tree, and a window with curtains.
A bedroom with a large bed, a nightstand with a lamp, a chair, and a framed picture on the wall.
Front of property
Living area

9. Arthur's Country Inn

Arthur's Country Inn
Arthur
NT$3,811
NT$4,229 total
includes taxes & fees
Oct 5 - Oct 6
Arthur's Country Inn
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Choose what matters most at spa hotels in Southern Illinois

Pool
Breakfast included
Hot tub
4 stars
5 stars

Top Southern Illinois Hotel Reviews

Comfort Suites Mount Vernon

Comfort Suites Mount Vernon

8/10 Good
"Finally a room with a walk in shower and grab bars by toilet"
Anjanette 1-night trip
Posted 3 hours ago
Comfort Suites Mount Vernon
Drury Inn & Suites St. Louis O'Fallon, IL

Drury Inn & Suites St. Louis O'Fallon, IL

10/10 Excellent
"Fabulous that I arrived & had Happy Hour Meal with Drinks & a great breakfast! Thx! Dennis D."
Dennis 1-night trip
Posted 16 hours ago
Drury Inn & Suites St. Louis O'Fallon, IL
Country Inn & Suites by Radisson, Effingham, IL

Country Inn & Suites by Radisson, Effingham, IL

10/10 Excellent
"GREAT PLACE! Comfortable beds, great pillow, excellent breakfast with extended hours compared to other places I've stayed. Would definitely stay again."
Chuck 1-night trip
Posted 20 hours ago
Country Inn & Suites by Radisson, Effingham, IL
Harrah's Metropolis Hotel & Casino - A Caesars Rewards Destination

Harrah's Metropolis Hotel & Casino - A Caesars Rewards Destination

10/10 Excellent
"not full and quiet for a casino environment."
Sophie 1-night trip
Posted 3 days ago
Harrah's Metropolis Hotel & Casino - A Caesars Rewards Destination

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