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Find Family Hotels in Southern Illinois, IL

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Our top choices for Southern Illinois family-friendly hotels

Hampton Inn & Suites Effingham

Hampton Inn & Suites Effingham
2.5 star property
Effingham
9.6 out of 10, Exceptional, (680)
"Great place. Clean and very comfortable rooms. Great breakfast"
United States
Luis
The price is NT$3,336
NT$3,703 total
includes taxes & fees
Jan 18 - 2026/1/19
Hampton Inn & Suites Effingham

La Quinta Inn & Suites by Wyndham Effingham

La Quinta Inn & Suites by Wyndham Effingham
3.0 star property
Effingham
9.2 out of 10, Wonderful, (1006)
"Clean, pleasant, fast check in, and warm pool! I have stayed here 2 times before and have already booked a room for my return trip here. Great place to stay!"
United States
Barbara
The price is NT$2,924
NT$3,275 total
includes taxes & fees
Jan 4 - 2026/1/5
La Quinta Inn & Suites by Wyndham Effingham

Comfort Suites Mount Vernon

Comfort Suites Mount Vernon
2.5 star property
Mount Vernon
9.0 out of 10, Wonderful, (1007)
"Check in was quick, staff was friendly and helpful, room was very nice and clean."
United States
Don
The price is NT$3,438
NT$3,879 total
includes taxes & fees
Dec 31 - 2026/1/1
Comfort Suites Mount Vernon

Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon
3.0 star property
Mount Vernon
9.6 out of 10, Exceptional, (1590)
"Great place to stay. Check in is easy and the hotel people are very nice."
United States
Duane
The price is NT$2,965
NT$3,353 total
includes taxes & fees
Jan 6 - 2026/1/7
Drury Plaza Hotel Mt. Vernon

Drury Inn & Suites Marion

Drury Inn & Suites Marion
3.0 star property
Marion
9.4 out of 10, Exceptional, (1006)
"Hotel is very clean and staff is also friendly."
United States
Tonya
The price is NT$2,050
NT$2,460 total
includes taxes & fees
Jan 18 - 2026/1/19
Drury Inn & Suites Marion

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
2.5 star property
Murphysboro
9.4 out of 10, Exceptional, (512)
"great property, great breakfast, friendly and knowledgable staff."
United States
Ronald
The price is NT$3,062
NT$3,398 total
includes taxes & fees
Dec 26 - Dec 27
Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

Quality Inn & Suites Metropolis I-24

Quality Inn & Suites Metropolis I-24
2.5 star property
Metropolis
8.0 out of 10, Very Good, (1006)
"Courteous staff, clean rooms. "
United States
Jennifer
The price is NT$1,746
NT$2,032 total
includes taxes & fees
Jan 11 - 2026/1/12
Quality Inn & Suites Metropolis I-24

Best Western Plus Centralia Hotel & Suites

Best Western Plus Centralia Hotel & Suites
2.5 star property
Centralia
9.6 out of 10, Exceptional, (603)
"Very beautiful place to stay "
United States
Valerie
The price is NT$3,804
NT$4,260 total
includes taxes & fees
Jan 5 - 2026/1/6
Best Western Plus Centralia Hotel & Suites

Super 8 by Wyndham Mt. Vernon IL

Super 8 by Wyndham Mt. Vernon IL
2.5 star property
Mount Vernon
7.8 out of 10, Good, (1002)
"reception was great, room clean, and the price was right."
United States
tom
The price is NT$1,932
NT$2,207 total
includes taxes & fees
Jan 4 - 2026/1/5
Super 8 by Wyndham Mt. Vernon IL

Holiday Inn Carbondale-Conference Center by IHG

Holiday Inn Carbondale-Conference Center by IHG
3.0 star property
Carbondale
8.8 out of 10, Excellent, (644)
"Great staff!"
United States
Greg
The price is NT$3,567
NT$4,101 total
includes taxes & fees
Dec 24 - Dec 25
Holiday Inn Carbondale-Conference Center by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Southern Illinois Hotel Reviews

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