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Check availability on Southern Illinois Business Hotels

Our top choices for Southern Illinois business-friendly hotels

Lobby lounge

Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon
3.0 star property
Mount Vernon
9.6 out of 10, Exceptional, (1,655 reviews)
"Hotel is very clean, nicely furnished and the beds were so comfy!"
United States
Christina
The price is NT$3,510
NT$3,959 total
includes taxes & fees
Feb 23 - Feb 24
Drury Plaza Hotel Mt. Vernon
Lobby

Drury Inn & Suites Marion

Drury Inn & Suites Marion
3.0 star property
Marion
9.4 out of 10, Exceptional, (1,002 reviews)
"All of the above, enjoyed the evening meal and breakfast, also staff was very friendly. "
United States
Barbara
The price is NT$2,955
NT$3,545 total
includes taxes & fees
Feb 22 - Feb 23
Drury Inn & Suites Marion
Exterior

Holiday Inn Express & Suites Effingham by IHG

Holiday Inn Express & Suites Effingham by IHG
2.5 star property
Effingham
9.4 out of 10, Exceptional, (1,001 reviews)
"Room was clean, staff was very pleasant, breakfast was delicious and plentiful and we were able to enjoy all amenities. "
United States
Laura
The price is NT$3,458
NT$3,873 total
includes taxes & fees
Feb 22 - Feb 23
Holiday Inn Express & Suites Effingham by IHG
Free daily continental breakfast

Best Western U. S. Inn

Best Western U. S. Inn
2.5 star property
Nashville
8.6 out of 10, Excellent, (400 reviews)
"Great and clean hotel"
United States
Jose
The price is NT$2,758
NT$3,006 total
includes taxes & fees
Feb 23 - Feb 24
Best Western U. S. Inn
Exterior

La Quinta Inn & Suites by Wyndham Effingham

La Quinta Inn & Suites by Wyndham Effingham
3.0 star property
Effingham
9.2 out of 10, Wonderful, (1,001 reviews)
"Staff was amazing and the brekfast was good too!"
United States
Kevin
The price is NT$3,038
NT$3,402 total
includes taxes & fees
Mar 8 - Mar 9
La Quinta Inn & Suites by Wyndham Effingham
Front of property - evening/night

Country Inn & Suites by Radisson, Effingham, IL

Country Inn & Suites by Radisson, Effingham, IL
2.5 star property
Effingham
8.8 out of 10, Excellent, (1,000 reviews)
"Clean, friendly staff and good breakfast. Location is excellent. "
United States
Maria
The price is NT$2,798
NT$3,105 total
includes taxes & fees
Mar 9 - Mar 10
Country Inn & Suites by Radisson, Effingham, IL
Meeting facility

Holiday Inn Effingham by IHG

Holiday Inn Effingham by IHG
3.5 star property
Effingham
9.0 out of 10, Wonderful, (663 reviews)
"Nice place with bar and restaurant on site."
United States
Steve
The price is NT$3,135
NT$3,510 total
includes taxes & fees
Feb 28 - Mar 1
Holiday Inn Effingham by IHG
Lobby

Ramada by Wyndham Vandalia

Ramada by Wyndham Vandalia
2.0 star property
Vandalia
7.8 out of 10, Good, (818 reviews)
"The room was clean, the staff was friendly, respectful and very helpful "
United States
Dianna
The price is NT$2,132
NT$2,323 total
includes taxes & fees
Feb 19 - Feb 20
Ramada by Wyndham Vandalia
Lobby

SureStay Hotel by Best Western Whittington Rend Lake

SureStay Hotel by Best Western Whittington Rend Lake
2.5 star property
Whittington
8.8 out of 10, Excellent, (931 reviews)
"Great place to stay."
United States
Stephen
The price is NT$2,398
NT$2,661 total
includes taxes & fees
Feb 23 - Feb 24
SureStay Hotel by Best Western Whittington Rend Lake
Room, 2 Queen Beds, Non Smoking | Desk, laptop workspace, blackout drapes, iron/ironing board

Days Inn & Suites by Wyndham Casey

Days Inn & Suites by Wyndham Casey
2.0 star property
Casey
7.4 out of 10, Good, (838 reviews)
"The room was comfortable, but the furniture looked like it wasn't finished The cabinet under the TV had openings in the back that looked like the refrigerator was supposed to be inserted in the cabinet and micro wave was also supposed to be placed in the cabinet "
United States
Mary
The price is NT$1,865
NT$2,070 total
includes taxes & fees
Feb 22 - Feb 23
Days Inn & Suites by Wyndham Casey
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Southern Illinois Hotel Reviews

Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon

10/10 Excellent
"One of the better hotels I have stayed at! Super clean. Great service! Good food options! Liked the evening and breakfast offerings. Very pet friendly. Safe and secure!"
Richard 1-night trip
Posted 12 hours ago
Drury Plaza Hotel Mt. Vernon

Frequently asked questions

How much do business-friendly hotels in Southern Illinois cost?
You'll pay between NT$2,070 and NT$3,959 per night for business-friendly hotels in Southern Illinois. Awesome deals on properties that cater to work-related travelers are a few clicks away on Expedia. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
What are the best business-friendly hotels in Southern Illinois?
That depends on your destination in Southern Illinois. Many business travelers to O'Fallon like to base themselves at Drury Inn & Suites St. Louis O'Fallon, IL. This 3-stars property comes with a swimming pool and complimentary breakfast. Hampton Inn O'Fallon is another top option if you're attending a conference or working remotely in O'Fallon. A swimming pool and an electric car charging station are among the handy amenities at this 2.5-stars getaway. When work takes you on the road, you can choose from multiple business-friendly hotels in Southern Illinois that have a total average guest review rating of 8.7.
How many business-friendly hotels are there in Southern Illinois?
Pick from 149 business-friendly hotels in Southern Illinois. Wherever your job is taking you, Expedia makes it a breeze to find the ideal space with the amenities you want.
What are the best cheap business-friendly hotels in Southern Illinois?
Keep costs low with Expedia's business-friendly hotels in Southern Illinois that start at NT$2,070 per night. A cheaper property in O'Fallon is Hampton Inn O'Fallon. Corporate guests rate it highly for its many amenities, including an electric car charging station and a swimming pool. If you're basing yourself in Effingham, choose Holiday Inn Express And Suites Effingham, an IHG Hotel. A swimming pool and a garden are among the conveniences provided for both business and leisure travelers. You'll find loads of free and interesting things to do wherever you go in Southern Illinois. If you have a meeting or conference in O'Fallon, try to find time to visit St. Clair Bowl. You can also go sightseeing for a song in Effingham. Mid America Motorworks, My Garage Museum is one of the best free attractions here. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
Are there any family-friendly hotels in Southern Illinois that are also business friendly?
You'll discover some terrific family-friendly hotels that are also business friendly in Southern Illinois. If you're traveling to O'Fallon, look up Drury Inn & Suites St. Louis O'Fallon, IL. It offers handy amenities such as complimentary breakfast and a laundry service and has a 3-stars rating. Another property worth considering is Drury Inn & Suites St. Louis Fairview Heights. This 3-stars stay in O'Fallon is ideal for both leisure and business travelers and offers complimentary breakfast, a laundry service and much more. Once you've gotten work out of the way, get out and discover O'Fallon with the kids. Favorite family-friendly attractions include The Edge and St. Clair Bowl.
Why book your business-friendly hotel in Southern Illinois with Expedia?
At Expedia, we make it our job to help you locate an amazing stay at the right price. From luxurious, corporate-friendly properties to affordable hotels filled with handy amenities, you'll have your next work trip booked in a few easy clicks.
How can I find cheap business-friendly hotels in Southern Illinois?
When you're traveling for work in Southern Illinois, our "business friendly" filter will help you find the ideal hotel. From free WiFi to workspaces and meeting rooms, they have the amenities you need to be productive. Another useful tip? Refine your search by your budget and preferred star rating to view the most affordable options.
What is there to do in Southern Illinois near my business-friendly hotel?
Southern Illinois has so much to see and do, it can be tricky to figure out where to start. If you're spending a few nights in O'Fallon, The Edge is a much-loved attraction here.

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