Downtown, SC
Seneca
Visit Downtown
Stay near popular Downtown attractions
Downtown Hotel Deals
Quality Inn Seneca Clemson Area US-123
226 Hi Tech Rd Seneca SC
The price is NT$2,673 per night from Aug 1 to Aug 2
NT$2,673
NT$3,262 total
Aug 1 - Aug 2
includes taxes & fees
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
Days Inn by Wyndham Anderson
1007 George Smith Mill Rd Anderson SC
The price is NT$1,949 per night from Aug 27 to Aug 28
NT$1,949
NT$2,163 total
Aug 27 - Aug 28
includes taxes & fees
Book a stay at this business-friendly motel in Anderson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Best Western Plus Clemson Hotel & Conference Center
1310 Tiger Blvd Clemson SC
The price is NT$3,540 per night from Aug 1 to Aug 2
NT$3,540
NT$3,930 total
Aug 1 - Aug 2
includes taxes & fees
Book a stay at this business-friendly hotel in Clemson. Enjoy free breakfast, free parking, and an outdoor pool. Our guests praise the helpful staff and the ...
The Shepherd Hotel Downtown Clemson
110 Sloan St Clemson SC
The price is NT$6,426 per night from Aug 2 to Aug 3
NT$6,426
NT$7,132 total
Aug 2 - Aug 3
includes taxes & fees
Stay at this hotel in Clemson. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean rooms in our reviews. ...
9.8/10 Exceptional! (855 reviews)
"The late check out was helpful with a college tour at 9:00 am."
Reviewed on 2026/7/27
Lakeside Lodge Clemson
13500 Clemson Blvd Seneca SC
The price is NT$3,520 per night from Aug 1 to Aug 2
NT$3,520
NT$4,369 total
Aug 1 - Aug 2
includes taxes & fees
Stay at this hotel in Seneca. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
9/10 Wonderful! (1,012 reviews)
"Amazing stay and great location"
Reviewed on 2026/7/28
Comfort Inn & Suites Clemson - University Area
1305 Tiger Blvd Clemson SC
The price is NT$3,403 per night from Aug 27 to Aug 28
NT$3,403
NT$3,778 total
Aug 27 - Aug 28
includes taxes & fees
Book a stay at this business-friendly hotel in Clemson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (1,004 reviews)
"I recomend this place to everyone"
Reviewed on 2026/7/26
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Downtown
Find the best Downtown areas and neighborhoods for the activities you enjoy most.
Serenity Bay
Though Serenity Bay might not have many top sights, you can venture to the surrounding area to see attractions like Keowee Key Golf Course and Lake Keowee.
Pine Ridge Point
While Pine Ridge Point isn't home to many top sights, South Beach and Lake Keowee are some notable places to visit nearby.
Indian Oaks
While there might not be top attractions in Indian Oaks, you can explore the larger area and discover places like Keowee Reservoir and Oconee County Library Seneca Branch.
Keowee Plantation
When in Keowee Plantation, you can plan a visit to Keowee Reservoir and Oconee County Library Seneca Branch, some noteworthy sights in the nearby area.
