Find hotels in Santa Maria from NT$1,301

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Dec 29 - Dec 30
Tomorrow
Dec 30 - Dec 31
This weekend
Jan 2 - Jan 4
Next weekend
Jan 9 - Jan 11

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Santa Maria hotels

Interior
Casona El Resguardo

Casona El Resguardo

Casona El Resguardo
3.0 star property
San Esteban
9.6 out of 10, Exceptional, (5)
"Lovely stay in this BnB style hotel. The food was the best part! Excellent chef that makes a special meal nightly considering all dietary restrictions. Location close enough to Portillo Ski resort to drive for daily skiing. Highly recommend. "
United States
Anonymous traveler
The price is NT$4,366
NT$4,366 total
Jan 4 - 2026/1/5
Casona El Resguardo
Superior Double Room
Hotel y Cabañas Palomar - Caja los Andes

Hotel y Cabañas Palomar - Caja los Andes

Hotel y Cabañas Palomar - Caja los Andes
2.0 star property
San Felipe
9.4 out of 10, Exceptional, (3)
"Excelente "
Costa Rica
Anonymous traveler
The price is NT$2,074
NT$2,074 total
Jan 5 - 2026/1/6
Hotel y Cabañas Palomar - Caja los Andes
Exterior detail
Inca Hoteles

Inca Hoteles

Inca Hoteles
3.5 star property
Los Andes
9.2 out of 10, Wonderful, (135)
"Restaurant and breakfast buffet are delicious! Rooms were perfect size and very clean. Staff is incredibly friendly and helpful. Easy drive to Portillo to ski! "
United States
CAMERON
The price is NT$3,458
NT$3,458 total
Dec 30 - Dec 31
Inca Hoteles
Front of property
Hotel Genova

Hotel Genova

Hotel Genova
2.5 star property
Los Andes
7.2 out of 10, Good, (39)
"The staff wasn’t very friendly Good place to stay."
United States
Jose
The price is NT$1,301
NT$1,301 total
Jan 4 - 2026/1/5
Hotel Genova
Sauna, hot tub, steam room, hot springs, mud baths, massages
Termas el Corazon

Termas el Corazon

Termas el Corazon
3.0 star property
Los Andes
7.2 out of 10, Good, (10)
"Perfect place to relax. Clean, quiet with great food and excellent service"
Canada
Jean-Luc
Termas el Corazon
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Stay near popular Santa Maria attractions

El Zaino Dreaming Stones

You can find out about the history of Santa Maria with a stop at El Zaino Dreaming Stones.
See properties

Top Santa Maria Hotel Reviews

Casona El Resguardo

Casona El Resguardo

10/10 Excellent
"Lovely stay in this BnB style hotel. The food was the best part! Excellent chef that makes a special meal nightly considering all dietary restrictions. Location close enough to Portillo Ski resort to drive for daily skiing. Highly recommend. "
Anonymous traveler 3-night trip
Posted 4 months ago
Casona El Resguardo

More cheap stays in Santa Maria

Hotel Genova

Hotel Genova

523 Las Heras Los Andes Región de Valparaíso
The price is NT$1,301 per night from Jan 4 to Jan 5
NT$1,301
NT$1,301 total
Jan 4 - 2026/1/5
7.2/10 Good! (39 reviews)

Frequently asked questions

Where is the best place to stay in Santa Maria?
Based on our traveler data, Termas Jahuel Hotel & Spa is one of the top choices for your stay. This hotel offers a full-service spa and a restaurant. Two other options for your stay in the area are Hotel Genova and Termas el Corazon. See all available top hotels, or vacation rentals in Santa Maria.
If I need to cancel my hotel reservation in Santa Maria, will I receive a refund?
Yes, the majority of hotel bookings are refundable provided that you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before check in. If your reservation is non-refundable, you may still be able to cancel and be given a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Santa Maria.
Where can I learn more about changing or cancelling my trip to Santa Maria?
For additional details about changing or cancelling your trip to Santa Maria, click here.
What's the best accommodation for an all-inclusive stay in Santa Maria?
Termas Jahuel Hotel & Spa is an all-inclusive hotel featuring a full-service spa and a health club, and a favorite with Expedia travelers. See more all-inclusive resorts in Santa Maria.
What's the best hotel for staying near Arturo Merino Benitez Airport (SCL)?
Holiday Inn Santiago - Airport Terminal is a popular 3.5-star hotel featuring free extended parking and a restaurant. It's located a short 0.1 mi (0.2 km) from Arturo Merino Benitez Airport. Other good choices near the airport include Hotel Diego de Almagro Aeropuerto - Santiago and City Express Santiago Aeropuerto.
What is staying in Santa Maria like?
Travelers to Santa Maria will find plenty to explore and enjoy. There are 23 hotels and other accommodations in the surrounding area. Find out more about Santa Maria.
What is there to see in Santa Maria?
A favorite place to visit is El Zaino Dreaming Stones. You'll also find Termas El Corazón and Museo Antiguo Monasterio del Espíritu Santo in the area. Check out what more to see and do in Expedia's Santa Maria guide.
What's the weather like in Santa Maria?
The hottest months are usually January and February with an average temp of 69°F, while the coldest months are July and June with an average of 50°F. Average annual precipitation for Santa Maria is 14 inches.