Find hotels in Santa Ana, Panama City from NT$1,682

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Oct 14 - Oct 15
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Oct 17 - Oct 19
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Discover 1,527 Santa Ana hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Luxury Apartment | Balcony
Casco View Apartments
Casco View Apartments
3.5 star property
9.4 out of 10, Exceptional, (48)
"Great stay, would recommend."
Casco View Apartments
Balcony
Hotel República
Hotel República
2.0 star property
6.6 out of 10, (176)
"Fantastic customer service"
Hotel República
Front of property
ART CASCO The Hotel
ART CASCO The Hotel
2.0 star property
6.6 out of 10, (8)
"Walkable location and free secure parking! The price is really affordable, but the condition of the hotel is not the best"
ART CASCO The Hotel
Bar (on property)
Hostal La Cigarra
Hostal La Cigarra
2.5 star property
7.4 out of 10, Good, (53)
"Helpful staff, secure, close to sights"
Hostal La Cigarra
Single Room | Free WiFi, bed sheets
Hotel Riazor
Hotel Riazor
3.0 star property
3.8 out of 10, (11)
"Rough neighborhood "
Hotel Riazor
Apartment (20) | 1 bedroom, iron/ironing board, free WiFi, bed sheets
La Manzana by Wynwood House
La Manzana by Wynwood House
3.0 star property
7.0 out of 10, Good, (14)
"Great hotel. Very close to Casco viejo"
The price is NT$1,302
NT$2,046 total
includes taxes & fees
Oct 15 - Oct 16
La Manzana by Wynwood House
Room, Multiple Bedrooms, Accessible, Smoking | Pool | Outdoor pool
Room-sofa Bed Stay Rooftop Pool & Gym, A
Room-sofa Bed Stay Rooftop Pool & Gym, A
2.0 star property
2.0 out of 10, (1)
"You pay for a space in the apartment, it’s not the whole apartment be careful. The owner or whoever manages doesn’t give care about you as costumers they just want the money"
The price is NT$4,500
NT$4,950 total
includes taxes & fees
Nov 2 - Nov 3
Room-sofa Bed Stay Rooftop Pool & Gym, A
Outdoor pool, pool umbrellas, sun loungers
Crowne Plaza Panama Airport by IHG
Crowne Plaza Panama Airport by IHG
4.0 star property
8.4 out of 10, Very Good, (2243)
"Great location "
The price is NT$3,291
NT$3,620 total
includes taxes & fees
Nov 1 - Nov 2
Crowne Plaza Panama Airport by IHG
47-inch flat-screen TV with cable channels, TV
Central Hotel Panama Casco Viejo
Central Hotel Panama Casco Viejo
4.0 star property
9.0 out of 10, Wonderful, (1007)
"Very beautiful hotel with helpful staff. Very good dining options. "
Central Hotel Panama Casco Viejo
Exclusive House | Terrace/patio
La Concordia Boutique Hotel
La Concordia Boutique Hotel
4.0 star property
9.4 out of 10, Exceptional, (187)
"Beautiful boutique hotel. Our room was large, bed is comfortable, nice selection of pillows, large balcony. Hotel staff is friendly and helpful. I highly recommend this place."
La Concordia Boutique Hotel
Reception
Hotel Coral Suites
Hotel Coral Suites
3.5 star property
9.0 out of 10, Wonderful, (1006)
"Great location with spacious rooms "
The price is NT$2,127
NT$2,340 total
includes taxes & fees
Oct 15 - Oct 16
Hotel Coral Suites
Living area
ORHO HOTEL BOUTIQUE PANAMA Airport
ORHO HOTEL BOUTIQUE PANAMA Airport
2.0 star property
8.4 out of 10, Very Good, (9)
"Very nice boutique hotel"
The price is NT$3,489
NT$3,837 total
includes taxes & fees
Oct 16 - Oct 17
ORHO HOTEL BOUTIQUE PANAMA Airport
Exterior
TRYP by Wyndham Panamá Centro
TRYP by Wyndham Panamá Centro
3.5 star property
9.0 out of 10, Wonderful, (1016)
"Staff was very friendly and breakfast option were wide"
The price is NT$2,579
NT$2,836 total
includes taxes & fees
Oct 15 - Oct 16
TRYP by Wyndham Panamá Centro
Outdoor pool, sun loungers
Hotel Riu Plaza Panama
Hotel Riu Plaza Panama
5.0 star property
9.0 out of 10, Wonderful, (4398)
"Great buffet, nice pool."
The price is NT$3,643
NT$4,007 total
includes taxes & fees
Nov 5 - Nov 6
Hotel Riu Plaza Panama
Outdoor pool, open 7:00 AM to 10:30 PM, free cabanas, pool umbrellas
Riande Aeropuerto Hotel & Casino
Riande Aeropuerto Hotel & Casino
4.0 star property
8.6 out of 10, Excellent, (1906)
"Nice hotel, close to the airport, friendly staff"
The price is NT$5,849
NT$6,434 total
includes taxes & fees
Oct 16 - Oct 17
Riande Aeropuerto Hotel & Casino
Front of property
Megapolis Hotel Panamá
Megapolis Hotel Panamá
4.5 star property
8.4 out of 10, Very Good, (1124)
"Great stay "
The price is NT$3,961
NT$4,357 total
includes taxes & fees
Nov 7 - Nov 8
Megapolis Hotel Panamá
Front of property - evening/night
Principe Hotel and Suites
Principe Hotel and Suites
3.0 star property
9.0 out of 10, Wonderful, (1514)
"Great place to stay"
The price is NT$1,529
NT$1,682 total
includes taxes & fees
Oct 24 - Oct 25
Principe Hotel and Suites
Front of property
Novotel Panama City
Novotel Panama City
4.0 star property
9.0 out of 10, Wonderful, (1020)
"Room was always well attended to staff was very friendly and kind breakfast was gd 💕"
The price is NT$2,956
NT$3,252 total
includes taxes & fees
Nov 7 - Nov 8
Novotel Panama City
Outdoor pool, open 9:00 AM to 9:00 PM, sun loungers
Hospedium Princess Hotel Panama
Hospedium Princess Hotel Panama
3.5 star property
7.6 out of 10, Good, (643)
"The property itself was clean and felt safe. Convenient location close to different restaurants and ease of transportation options."
The price is NT$1,629
NT$1,792 total
includes taxes & fees
Oct 15 - Oct 16
Hospedium Princess Hotel Panama
Couples treatment rooms, sauna, steam room, body treatments
Bristol Panama, a Registry Collection Hotel
Bristol Panama, a Registry Collection Hotel
5.0 star property
9.2 out of 10, Wonderful, (1008)
"We had an amazing time, great hotel and great breakfast. "
The price is NT$5,752
NT$6,328 total
includes taxes & fees
Oct 31 - Nov 1
Bristol Panama, a Registry Collection Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Santa Ana

Find the best Santa Ana areas and neighborhoods for the activities you enjoy most.

Casco Viejo

Unique features of Casco Viejo include the historic sites and bars. Make a stop by Interoceanic Canal Museum or National Theater while you're exploring the area.

Bella Vista

Bella Vista is highly notable for its popular shops, and you might want to visit top sights like Via Espana and Iglesia del Carmen. See more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina.

El Cangrejo

The abundant dining options and casinos are top of the list for many visitors to El Cangrejo. A stop by Crown Casino or Luxor Towers might round out your trip.

San Francisco

San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50.

Punta Paitilla

Travelers come to Punta Paitilla for its abundant dining options, and you can see top attractions like Avenida Balboa and Multicentro Panama while you're in town.

Top Santa Ana Hotel Reviews

Megapolis Hotel Panamá

Megapolis Hotel Panamá

10/10 Excellent
"I will give this property a five star because it was in the heart of everything, restaurants, shopping, excursions, casino, nightlife and it was connected to the mall. It’s was easy getting Uber to and from the property. The breakfast was delicious every morning. The pool had some of the best views in Panama They also offer a very good happy hour at the pool and at the upstairs bar. The only problem we had with this property is the bed was extremely hard. Every night we put the pillows on top of the mattress and lay on pillows. I still will say this property is a 10/10 and I would highly recommend. "
Taneshia M 4-night trip
Posted 15 hours ago
Megapolis Hotel Panamá

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Frequently asked questions

What's it like in Santa Ana?
Santa Ana is a neighborhood that travelers like for its seafood restaurants, shopping, and parks. Are you looking for Santa Ana travel tips? Be sure to check out Cinta Costera and Avenida Balboa while you're in the neighborhood.
Where is the best hotel for a stay in Santa Ana?
Based on Expedia customer reviews, Hotel República is the highest ranked property in Santa Ana. This hotel is a short 4-minute walk from Avenida Balboa, and it offers a rooftop terrace and free WiFi. Another top choice in the area is Hostal La Cigarra.
How many hotels can I expect to find in Santa Ana?
Expedia has 110 hotels and other accommodations in Santa Ana to choose from, making this an ideal home base for exploring the greater Panama City area.
If I need to cancel my hotel reservation in Santa Ana, will I receive a refund?
Yes! Most hotel room reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a non-refundable reservation, it might still be possible to cancel it and be given a refund within a 24-hour period of your booking. Add dates, click "Search", then use the "fully refundable" filter to get top deals in Santa Ana.
Where can I learn more about changing or cancelling my trip to Santa Ana?
To find more details about picking new dates or cancelling your trip to Santa Ana, head over to our customer service page.
What is there to do in this Panama City neighborhood?
If you're looking forward to a day of shopping in Santa Ana, consider Avenida Central or Avenida Balboa, and pick out the perfect souvenir. A visit to Cinta Costera is also worth the trip while you're discovering the neighborhood. Albrook Shopping Mall, Amador Theater, and Museum of Contemporary Art Panama are just a few of the places to visit in and around Santa Ana. When you're sightseeing in Panama City, Mi Pueblito and Iglesia de la Merced are also worth a stop.