The Best Hotels Closest to Santa Ana National Wildlife Refuge in Alamo for 2026

A dirt path surrounded by trees with hanging moss.

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Our top choices for Santa Ana National Wildlife Refuge hotels

A modern lobby with a sectional sofa, a fireplace, and a mural of a horse.

A hotel room with a sofa, armchair, coffee table, and a TV. There is a kitchenette with a microwave and a sink. The room has carpeted flooring and a door leading to another room.

A modern hotel lobby with a reception desk, seating areas, and a dining space.

A modern lobby with a sectional sofa, a fireplace, and a TV mounted on the wall.

1. La Quinta Inn & Suites by Wyndham Pharr RGV Medical Center

17.2 km from Santa Ana National Wildlife Refuge

Victor Manuel

NT$2,555

NT$2,887 total

includes taxes & fees

Sep 14 - Sep 15

A swimming pool with stone walls and signs, surrounded by a paved area with chairs.

A modern living room with a sofa, a dining table, a TV, and a view of buildings through a window.

A Hampton Inn & Suites hotel with a classic facade, stone accents, and a welcoming entrance.

A hotel room with a bed, desk, chair, and a TV.

2. Hampton Inn & Suites Mission

19 km from Santa Ana National Wildlife Refuge

Sergio

NT$2,828

NT$3,212 total

includes taxes & fees

Sep 13 - Sep 14

A spacious lobby with a reception desk, seating area, and a staircase to an upper level.

A modern restaurant with multiple tables and chairs, a flat-screen TV mounted on the wall, and a patterned floor.

A hotel room with a large bed, a sofa, a desk, a chair, and a small kitchenette.

A Best Western Plus hotel with a modern facade, multiple windows, and a parking area.

3. Best Western Plus McAllen Airport Hotel

14.6 km from Santa Ana National Wildlife Refuge

hidalia

NT$3,113

NT$3,580 total

includes taxes & fees

Sep 13 - Sep 14

A modern snack area with a refrigerator, shelves stocked with snacks, and a sign indicating the location.

A modern hotel with a prominent "HOME 2" sign, a covered entrance, and a well-lit facade.

A hotel room with a bed, a desk with a TV, a kitchenette, a bathroom, and a living area with a sofa and lamp.

4. Home2 Suites By Hilton San Juan

11.7 km from Santa Ana National Wildlife Refuge

Latasha

NT$2,698

NT$2,995 total

includes taxes & fees

Sep 13 - Sep 14

A hotel with a swimming pool, lounge chairs, and palm trees.

A kitchenette with a coffee machine, microwave, toaster, and various appliances.

A hotel room with two beds, a desk with a coffee machine, a trash bin, and framed pictures on the wall.

A fitness room with a treadmill, exercise bike, and fan.

5. Super 8 by Wyndham Weslaco

19 km from Santa Ana National Wildlife Refuge

Luis

NT$1,856

NT$2,097 total

includes taxes & fees

Sep 23 - Sep 24

A pool area with columns, a pergola, and a palm tree.

A reception desk with a digital screen displaying a military discount offer.

A modern waiting area with a sofa, chairs, and a large window offering a view of the street.

6. Wyndham Garden McAllen at La Plaza Mall

14.5 km from Santa Ana National Wildlife Refuge

Georgiana

NT$2,844

NT$3,271 total

includes taxes & fees

Sep 9 - Sep 10

A Best Western hotel entrance with a covered walkway, a 'Welcome' sign, and a parking garage in the background.

A lobby with seating, a vending machine, and a television.

A hotel room with two beds, a desk, a television, and a minibar.

A kitchen with a long counter, equipped with various appliances and utensils.

7. Best Western McAllen Medical Center

13.7 km from Santa Ana National Wildlife Refuge

NT$2,337

NT$2,688 total

includes taxes & fees

Sep 10 - Sep 11

A hotel lobby with a reception desk, a dining area, and a seating area with a green chair.

A Holiday Inn Express building with a modern design, featuring a prominent entrance and a well-lit facade.

A swimming pool with a waterfall feature, lounge chairs, and a blue fence.

A modern dining area with a long table, red chairs, and a coffee station.

8. Holiday Inn Express Hotel & Suites Mission-McAllen Area by IHG

18.9 km from Santa Ana National Wildlife Refuge

Yesenia

NT$2,405

NT$2,717 total

includes taxes & fees

Sep 13 - Sep 14

A hotel dining area with wooden tables and chairs, a central bar, and a kitchen in the background.

A multi-story Comfort Inn & Suites with a covered entrance, palm trees, and a parking lot.

A hotel reception area with a digital check-in kiosk, a sign for Comfort Inn & Suites, and a Christmas decoration on the ceiling.

A Comfort Inn & Suites with a pool area featuring lounge chairs and a stone facade.

9. Comfort Inn & Suites Donna near I-2

13.4 km from Santa Ana National Wildlife Refuge

maria

NT$2,259

NT$2,553 total

includes taxes & fees

Oct 4 - Oct 5

A pool area with red umbrellas, lounge chairs, and a building with a tiled roof.

A pathway flanked by lush greenery and trees, leading to a building with a red-tiled roof and a covered patio area.

A row of palm trees in front of a building with a red-tiled roof.

A modern living room with a flat-screen TV, two framed artworks, a sofa, a coffee table, and a black chair.

10. The Bungalows on Shary, Mission-McAllen

17.5 km from Santa Ana National Wildlife Refuge

Omar

NT$2,824

NT$3,191 total

includes taxes & fees

Sep 8 - Sep 9

An indoor swimming pool with lounge chairs, a diving board, and a mural of underwater scenery.

A hotel with a prominent sign, a covered entrance, and a landscaped area with palm trees.

A modern lounge area with a ceiling design, seating arrangements, and a reception desk.

A modern living room with a flat-screen TV, two sofas, a coffee table, and a fireplace.

11. La Quinta Inn & Suites by Wyndham Alamo - McAllen East

11.9 km from Santa Ana National Wildlife Refuge

Anne

NT$2,253

NT$2,546 total

includes taxes & fees

Sep 27 - Sep 28

A hotel room with two beds, a flat-screen TV, a desk, and a window with curtains.

A hotel entrance with a covered walkway, a handicap parking sign, and a fire lane.

A swimming pool with blue water, surrounded by lounge chairs and a building with multiple windows and a door.

A coffee machine with three dispensers, a coffee cup display, and a coffee cup on the wall.

12. Motel 6 Pharr, TX

17.1 km from Santa Ana National Wildlife Refuge

Luis

NT$1,651

NT$1,866 total

includes taxes & fees

Sep 25 - Sep 26

A breakfast buffet area with various food items and a sign that reads "HAPPY BREAKFAST STARTS HERE".

A hotel room with two beds, a desk, a chair, a large window, and a radiator.

A hotel reception desk with a 'Welcome to the Lone Star' sign, a 'Hilton Honors' badge, and a 'Suite Shop' sign.

A modern Hampton Inn hotel with a prominent entrance, large windows, and a well-lit facade.

13. Hampton Inn Weslaco

15.8 km from Santa Ana National Wildlife Refuge

Isaac

NT$3,087

NT$3,489 total

includes taxes & fees

Sep 15 - Sep 16

A Rodeway Inn with a covered entrance, palm trees, and a clear blue sky.

A hotel room with two beds, each with patterned bedspreads, a nightstand with a lamp, and two framed pictures on the wall.

A reception area with a wooden counter, a framed picture on the wall, and a sign about rewards.

A hotel room with a large bed, two bedside tables with lamps, and two framed pictures on the wall.

14. Rodeway Inn San Juan

12.9 km from Santa Ana National Wildlife Refuge

Danielle

NT$1,479

NT$1,642 total

includes taxes & fees

Sep 28 - Sep 29

A hotel room with a large bathtub, a bed with a patterned headboard, two bedside lamps, and a desk with a chair.

A lobby with a fireplace, four armchairs, a coffee table, and a television mounted above the fireplace.

A hotel with a prominent entrance, multiple floors, and a well-lit facade.

A chandelier hanging from a ceiling with recessed lighting.

15. Super 8 by Wyndham Hidalgo/McAllen Area

11.3 km from Santa Ana National Wildlife Refuge

Heriberto

NT$1,936

NT$2,188 total

includes taxes & fees

Sep 14 - Sep 15

A hotel room with a bed, a desk, a chair, a table, a ceiling fan, a TV, and a door.

A bathroom with a bathtub, shower, and toilet.

A compact kitchenette with a microwave, coffee maker, and a small refrigerator.

16. Texas Inn Donna

14.4 km from Santa Ana National Wildlife Refuge

Lisa

NT$2,064

NT$2,333 total

includes taxes & fees

Sep 13 - Sep 14

A modern kitchen with a central island, bar stools, and a breakfast sign indicating hours of operation.

A gym with treadmills, weight machines, and free weights.

A hotel with a modern architectural design, featuring a prominent 'aloft' sign and a covered entrance area.

An outdoor seating area with wooden furniture, colorful cushions, and umbrellas.

17. Aloft by Marriott McAllen

17.7 km from Santa Ana National Wildlife Refuge

Eugene

NT$2,931

NT$3,371 total

includes taxes & fees

Sep 13 - Sep 14

A hotel room with two beds, a desk with a chair, a TV, and a large window.

A conference room with a long table, green chairs, and framed artwork on the wall.

A coffee station with two coffee machines and a variety of coffee pods and cups.

A 1 Express hotel with a covered entrance, stone pillars, and a brick facade.

18. Holiday Inn Express & Suites McAllen - Medical Center Area by IHG

14.3 km from Santa Ana National Wildlife Refuge

Ana

NT$3,196

NT$3,675 total

includes taxes & fees

Sep 10 - Sep 11

A spacious indoor area with multiple tables and chairs, large windows, and a ceiling fan.

A spacious room with a wooden floor, a large chandelier, and a modern ceiling design.

A hotel room with a bed, a chair, a nightstand with a lamp, a vanity with a mirror and lights, and a framed picture on the wall.

A brick building with a brown awning labeled 'Victoria Restaurant.' There are palm trees and a parking lot in front.

19. Victoria Palms Inn & Suites

15.2 km from Santa Ana National Wildlife Refuge

raudel

NT$1,815

NT$2,051 total

includes taxes & fees

Sep 8 - Sep 9

20. McAllen Plaza Hotel & Suites

14.3 km from Santa Ana National Wildlife Refuge

Omobola

NT$2,541

NT$2,923 total

includes taxes & fees

Sep 8 - Sep 9

View all properties

Compare popular hotels close to Santa Ana National Wildlife Refuge

Property	Property class	Guest rating
La Quinta Inn & Suites by Wyndham Pharr RGV Medical Center	9.4 Exceptional 1,328 reviews	View
Hampton Inn & Suites Mission	9.6 Exceptional 11 reviews	View
Best Western Plus McAllen Airport Hotel	9.2 Wonderful 1,012 reviews	View
Home2 Suites By Hilton San Juan	9.6 Exceptional 703 reviews	View
Super 8 by Wyndham Weslaco	8.8 Excellent 1,003 reviews	View

Top Santa Ana National Wildlife Refuge Hotel Reviews

Wyndham Garden McAllen at La Plaza Mall

10/10 Excellent

"Great stay as always.Friendly staff. We love their breakfast . We keep coming back any time we visit. : )"

La Quinta Inn & Suites by Wyndham Alamo - McAllen East

8/10 Good

"Hotel was having construction. Room was clean and the beds were comfortable. Staff was friendly by hard to find."

Other attractions near Santa Ana National Wildlife Refuge

Basilica of Our Lady of San Juan del Valle

9.4/10 (759 reviews)

You can learn about the history of San Juan when you stop by Basilica of Our Lady of San Juan del Valle. Experience the live music or attend a sporting event in this family-friendly area.

See properties

Payne Arena

8.4/10 (364 reviews)

Catch an event at Payne Arena during your trip to Hidalgo. Experience the festivals and live music in this family-friendly area.

See properties

Jardin Botanico del Dr. Alfredo Barrera -Botanical Gardens

10.0/10 (1 review)

Explore the great outdoors at Jardin Botanico del Dr. Alfredo Barrera -Botanical Gardens, a lovely green space in Río Bravo.

See properties

World's Largest Killer Bee

8.4/10 (14 reviews)

You can learn about the history of Hidalgo when you stop by World's Largest Killer Bee. While in this family-friendly area, find time to visit its shops.

See properties

Old Hidalgo Pumphouse

8.8/10 (32 reviews)

You can study the exhibits at Old Hidalgo Pumphouse, a museum with a story of its own, during your travels to Hidalgo. While in this family-friendly area, find time to visit its shops.

See properties

Smitty's Juke Box Museum

7.8/10 (59 reviews)

You can spend time exploring the galleries in Smitty's Juke Box Museum in Pharr. Experience the live music and entertainment venues in this family-friendly area.

See properties

Puente Internacional Reynosa-Hidalgo

8.4/10 (325 reviews)

After visiting Puente Internacional Reynosa-Hidalgo, make a plan to see the other sights and activities in Reynosa. Experience the area's entertainment venues and jazz scene.

See properties

Reynosa Cultural Park

8.0/10 (105 reviews)

Take the family on an outing to Reynosa Cultural Park during your trip to Reynosa. Experience the area's live music and entertainment venues.

See properties

Frequently asked questions

What's the area like around Santa Ana National Wildlife Refuge?

Santa Ana National Wildlife Refuge is located in a family-friendly area of Alamo that travelers like for its sporting events and live music. Alamo is home to 10 hotels and other accommodations, so you can find something with the amenities you're looking for.

What's the best hotel to stay near Santa Ana National Wildlife Refuge?

La Quinta Inn & Suites by Wyndham Alamo - McAllen East is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an outdoor pool. You'll find it 7.4 mi (11.9 km) from Santa Ana National Wildlife Refuge. Another good option is Pharr Executive Inn, located 6.4 mi (10.3 km) away.

If I need to cancel the hotel reservation for my stay near Santa Ana National Wildlife Refuge, will I receive a refund?

Yes, most hotel room reservations are refundable if you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of check in. If your reservation is non-refundable, it might still be possible to cancel it and receive a refund within 24 hours of your booking. Plug in your dates, click on "Search", then use the filter option "fully refundable" to review the best deals available near Santa Ana National Wildlife Refuge.

Where can I learn more about changing or cancelling my trip in the area near Santa Ana National Wildlife Refuge?

For more details about updating your stay near Santa Ana National Wildlife Refuge or cancelling it, head over to our customer service page.

Find hotels near Santa Ana National Wildlife Refuge, Alamo

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Santa Ana National Wildlife Refuge hotels

1. La Quinta Inn & Suites by Wyndham Pharr RGV Medical Center

2. Hampton Inn & Suites Mission

3. Best Western Plus McAllen Airport Hotel

4. Home2 Suites By Hilton San Juan

5. Super 8 by Wyndham Weslaco

6. Wyndham Garden McAllen at La Plaza Mall

7. Best Western McAllen Medical Center

8. Holiday Inn Express Hotel & Suites Mission-McAllen Area by IHG

9. Comfort Inn & Suites Donna near I-2

10. The Bungalows on Shary, Mission-McAllen

11. La Quinta Inn & Suites by Wyndham Alamo - McAllen East

12. Motel 6 Pharr, TX

13. Hampton Inn Weslaco

14. Rodeway Inn San Juan

15. Super 8 by Wyndham Hidalgo/McAllen Area

16. Texas Inn Donna

17. Aloft by Marriott McAllen

18. Holiday Inn Express & Suites McAllen - Medical Center Area by IHG

19. Victoria Palms Inn & Suites

20. McAllen Plaza Hotel & Suites

Compare popular hotels close to Santa Ana National Wildlife Refuge

Top Santa Ana National Wildlife Refuge Hotel Reviews

Wyndham Garden McAllen at La Plaza Mall

La Quinta Inn & Suites by Wyndham Alamo - McAllen East

Other attractions near Santa Ana National Wildlife Refuge

Basilica of Our Lady of San Juan del Valle

Payne Arena

Jardin Botanico del Dr. Alfredo Barrera -Botanical Gardens

World's Largest Killer Bee

Old Hidalgo Pumphouse

Smitty's Juke Box Museum

Puente Internacional Reynosa-Hidalgo

Reynosa Cultural Park

Frequently asked questions

Explore a world of travel with Expedia