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Our top choices for Santa Ana National Wildlife Refuge hotels

A hotel room with two beds, a flat-screen TV, a desk, and a window with curtains.

1. Motel 6 Pharr, TX

Motel 6 Pharr, TX
2.0 star property
17.1 km from Santa Ana National Wildlife Refuge
9.0 out of 10, Wonderful, (1,716 reviews)
"Excelente hotel"
Mexico
Edna
The price is NT$1,543
NT$1,744 total
includes taxes & fees
Nov 23 - Nov 24
Motel 6 Pharr, TX
A hotel with a swimming pool, lounge chairs, and palm trees.

2. Super 8 by Wyndham Weslaco

Super 8 by Wyndham Weslaco
2.0 star property
19 km from Santa Ana National Wildlife Refuge
8.8 out of 10, Excellent, (1,002 reviews)
"All was good no complaints"
United States
Sandy
The price is NT$2,011
NT$2,272 total
includes taxes & fees
Nov 22 - Nov 23
Super 8 by Wyndham Weslaco
A modern Hampton Inn hotel with a prominent entrance, large windows, and a well-lit facade.

3. Hampton Inn Weslaco

Hampton Inn Weslaco
2.5 star property
15.8 km from Santa Ana National Wildlife Refuge
9.2 out of 10, Wonderful, (748 reviews)
"Excellent breakfast, parking and clean room"
United States
Miriam
The price is NT$3,323
NT$3,755 total
includes taxes & fees
Nov 29 - Nov 30
Hampton Inn Weslaco
A modern hotel with a prominent 'La Quinta' sign, a covered entrance, and a parking area with cars.

4. La Quinta Inn & Suites by Wyndham McAllen Convention Center

La Quinta Inn & Suites by Wyndham McAllen Convention Center
3.0 star property
17.5 km from Santa Ana National Wildlife Refuge
9.6 out of 10, Exceptional, (1,368 reviews)
"Quiet and great place to stay with excellent breakfast. Great tamales too! lvoed this place and will definitely stay here again. Deserves the high rating!"
United States
Tom
The price is NT$3,581
NT$4,118 total
includes taxes & fees
Nov 22 - Nov 23
La Quinta Inn & Suites by Wyndham McAllen Convention Center
Terrace/patio

5. Home2 Suites By Hilton San Juan

Home2 Suites By Hilton San Juan
3.0 star property
11.7 km from Santa Ana National Wildlife Refuge
9.6 out of 10, Exceptional, (739 reviews)
"This place is affordable and clean! The staff was very nice."
United States
Rosie Guadalupe
The price is NT$3,199
NT$3,551 total
includes taxes & fees
Dec 6 - Dec 7
Home2 Suites By Hilton San Juan
A modern lounge area with a blue sofa, white armchairs, and a dark sofa with colorful cushions. There are round tables and a neon sign on the wall.

6. Aloft by Marriott McAllen

Aloft by Marriott McAllen
3.0 star property
17.7 km from Santa Ana National Wildlife Refuge
9.2 out of 10, Wonderful, (779 reviews)
"Great hotel in a very good location"
United States
Ricardo
The price is NT$3,044
NT$3,500 total
includes taxes & fees
Nov 22 - Nov 23
Aloft by Marriott McAllen
A lobby with a reception desk, a Christmas tree, and a staircase.

7. Weslaco Inn Weslaco/Mercedes

Weslaco Inn Weslaco/Mercedes
2.0 star property
19.1 km from Santa Ana National Wildlife Refuge
8.4 out of 10, Very good, (662 reviews)
"Clean standard hotel with a friendly staff. Breakfast is very basic. Parking is ample and well lit. Good location to Progresso MX."
United States
Emilia
The price is NT$1,991
NT$2,621 total
includes taxes & fees
Nov 9 - Nov 10
Weslaco Inn Weslaco/Mercedes
A hotel entrance with a covered waiting area, a flag, and a sign indicating it's an Embassy Suites.

8. Embassy Suites by Hilton McAllen Convention Center

Embassy Suites by Hilton McAllen Convention Center
3.5 star property
17.3 km from Santa Ana National Wildlife Refuge
9.4 out of 10, Exceptional, (1,660 reviews)
"This is our staycation go to hotel, always a treat!"
United States
Nancy
The price is NT$3,283
NT$3,775 total
includes taxes & fees
Dec 6 - Dec 7
Embassy Suites by Hilton McAllen Convention Center
A hotel reception area with a counter, a wall sign reading 'Welcome to Hampton,' and a sign for 'Treats' with snacks and sundries.

9. Hampton Inn & Suites Mission

Hampton Inn & Suites Mission
3.0 star property
19 km from Santa Ana National Wildlife Refuge
9.2 out of 10, Wonderful, (69 reviews)
"Liked the location, rooms were clean and very friendly service."
United States
Ruben
The price is NT$2,802
NT$3,182 total
includes taxes & fees
Nov 22 - Nov 23
Hampton Inn & Suites Mission
A lobby with seating, a vending machine, and a television.

10. Best Western McAllen Medical Center

Best Western McAllen Medical Center
2.5 star property
13.7 km from Santa Ana National Wildlife Refuge
9.0 out of 10, Wonderful, (1,389 reviews)
"This is our go-to hotel when visiting family for the pool amenities and the layout of the rooms. We opt for a suite for the convenience with kids and privacy."
United States
Noriselda
The price is NT$2,699
NT$3,104 total
includes taxes & fees
Nov 22 - Nov 23
Best Western McAllen Medical Center
A modern building with a red and beige facade, large windows, and a parking lot with several cars.

11. Motel 6 Weslaco, TX

Motel 6 Weslaco, TX
2.0 star property
16.9 km from Santa Ana National Wildlife Refuge
8.6 out of 10, Excellent, (1,006 reviews)
"Clean room, staff was very helpful to any questions and checking out"
United States
Lesley
The price is NT$2,069
NT$2,338 total
includes taxes & fees
Nov 22 - Nov 23
Motel 6 Weslaco, TX
A spacious lobby with a reception desk, seating area, and a staircase to an upper level.

12. Best Western Plus McAllen Airport Hotel

Best Western Plus McAllen Airport Hotel
2.5 star property
14.6 km from Santa Ana National Wildlife Refuge
9.2 out of 10, Wonderful, (1,009 reviews)
"Central location, friendly staff, clean rooms and excellent breakfast."
United States
TIFFANY
The price is NT$3,390
NT$3,899 total
includes taxes & fees
Nov 15 - Nov 16
Best Western Plus McAllen Airport Hotel
A spacious dining area with multiple tables and chairs, a large flat-screen TV mounted on the wall, and a patterned carpet.

13. Verta Hotel McAllen

Verta Hotel McAllen
2.5 star property
13.8 km from Santa Ana National Wildlife Refuge
9.2 out of 10, Wonderful, (413 reviews)
"Staff were friendly and the breakfast was great"
United States
Moises
The price is NT$3,318
NT$3,816 total
includes taxes & fees
Dec 6 - Dec 7
Verta Hotel McAllen
A hotel with a modern design, featuring a prominent sign with a sun symbol and the name 'La Quinta Inn & Suites'. The building has multiple floors with a mix of brick and siding exteriors, and a covered entrance area.

14. La Quinta Inn & Suites by Wyndham Pharr North McAllen

La Quinta Inn & Suites by Wyndham Pharr North McAllen
3.0 star property
17 km from Santa Ana National Wildlife Refuge
9.2 out of 10, Wonderful, (1,647 reviews)
"Clean and comfortable room and property"
United States
Christopher
The price is NT$2,932
NT$3,313 total
includes taxes & fees
Nov 22 - Nov 23
La Quinta Inn & Suites by Wyndham Pharr North McAllen
A hotel lobby with a reception desk, a dining area, and a seating area with a green chair.

15. Holiday Inn Express Hotel & Suites Mission-McAllen Area by IHG

Holiday Inn Express Hotel & Suites Mission-McAllen Area by IHG
2.5 star property
18.9 km from Santa Ana National Wildlife Refuge
9.2 out of 10, Wonderful, (1,021 reviews)
"Excelente hotel"
Mexico
Veronica
The price is NT$2,858
NT$3,230 total
includes taxes & fees
Nov 11 - Nov 12
Holiday Inn Express Hotel & Suites Mission-McAllen Area by IHG
An outdoor seating area with a circular fire pit, surrounded by wicker furniture and palm trees.

16. Home2 Suites by Hilton McAllen

Home2 Suites by Hilton McAllen
3.0 star property
17.9 km from Santa Ana National Wildlife Refuge
9.2 out of 10, Wonderful, (797 reviews)
"Clean and staff was helpful"
United States
Juan
The price is NT$2,669
NT$3,069 total
includes taxes & fees
Nov 22 - Nov 23
Home2 Suites by Hilton McAllen
A library with bookshelves, a globe, and a mural.

17. Vali Ho Motel By OYO Weslaco Mercedes

Vali Ho Motel By OYO Weslaco Mercedes
2.0 star property
18.8 km from Santa Ana National Wildlife Refuge
8.4 out of 10, Very good, (239 reviews)
"The room was clean and ac worked well. It's for short stays."
United States
William
The price is NT$1,491
NT$1,833 total
includes taxes & fees
Nov 22 - Nov 23
Vali Ho Motel By OYO Weslaco Mercedes
A hotel room with a bed, a desk, a chair, a table, a ceiling fan, a TV, and a door.

18. Texas Inn Donna

Texas Inn Donna
2.5 star property
14.4 km from Santa Ana National Wildlife Refuge
8.8 out of 10, Excellent, (260 reviews)
"Nice place, if you Walter to go shopping to Mercedes and plaza malla this hotel is in betwen"
United States
Luis Fernando
The price is NT$2,217
NT$2,505 total
includes taxes & fees
Nov 9 - Nov 10
Texas Inn Donna
A spacious indoor area with multiple tables and chairs, large windows, and a ceiling fan.

19. Victoria Palms Inn & Suites

Victoria Palms Inn & Suites
2.5 star property
15.2 km from Santa Ana National Wildlife Refuge
8.4 out of 10, Very good, (1,000 reviews)
"This place is not a 5 star hotel but they sure try it was clean and the staff was friendly and the breakfast was good me and my wife were amazed"
United States
JESSE
The price is NT$2,262
NT$2,556 total
includes taxes & fees
Nov 12 - Nov 13
Victoria Palms Inn & Suites
A modern lobby with a reception desk, blue seating area, and a kitchen in the background.

20. Best Western Town Center Inn

Best Western Town Center Inn
2.5 star property
16.5 km from Santa Ana National Wildlife Refuge
8.6 out of 10, Excellent, (1,001 reviews)
"I loved everything about this place and will stay there again for sure"
United States
Rebeca
The price is NT$2,920
NT$3,299 total
includes taxes & fees
Nov 22 - Nov 23
Best Western Town Center Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels close to Santa Ana National Wildlife Refuge

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
A hotel room with two beds, a flat-screen TV, a desk, and a window with curtains.
Motel 6 Pharr, TX
2.0 star property
9.0
Wonderful
1,716 reviews
View
A hotel with a swimming pool, lounge chairs, and palm trees.
Super 8 by Wyndham Weslaco
2.0 star property
8.8
Excellent
1,002 reviews
View
A modern Hampton Inn hotel with a prominent entrance, large windows, and a well-lit facade.
Hampton Inn Weslaco
2.5 star property
9.2
Wonderful
748 reviews
View
A modern hotel with a prominent 'La Quinta' sign, a covered entrance, and a parking area with cars.
La Quinta Inn & Suites by Wyndham McAllen Convention Center
3.0 star property
9.6
Exceptional
1,368 reviews
View
Terrace/patio
Home2 Suites By Hilton San Juan
3.0 star property
9.6
Exceptional
739 reviews
View

Other attractions near Santa Ana National Wildlife Refuge

Basilica of Our Lady of San Juan del Valle

9.4/10 (759 reviews)
You can learn about the history of San Juan when you stop by Basilica of Our Lady of San Juan del Valle. Experience the live music or attend a sporting event in this family-friendly area.
See properties

Top Santa Ana National Wildlife Refuge Hotel Reviews

A modern kitchen with grey cabinets, stainless steel appliances, and a dining area with a glass table and chairs.
Elegant Apartment 10 min to Mercedes Outlets

Elegant Apartment 10 min to Mercedes Outlets

Elegant Apartment 10 min to Mercedes Outlets
Weslaco

10/10 Excellent

Cute and located within 30 min to the border. The apartment was in a safe area and has a nice vibe. Check-in instructions are provided same day. The owner was very nice when I had questions.
United States
Shawna
Reviewed March 31, 2025
Elegant Apartment 10 min to Mercedes Outlets

Frequently Asked Questions

What's the area like around Santa Ana National Wildlife Refuge?

Santa Ana National Wildlife Refuge is located in a family-friendly area of Alamo that travelers like for its sporting events and live music. Alamo is home to 8 hotels and other accommodations, so you can find something with the amenities you're looking for.

What's the best hotel to stay near Santa Ana National Wildlife Refuge?

La Quinta Inn & Suites by Wyndham Alamo - McAllen East is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an outdoor pool. You'll find it 7.4 mi (11.9 km) from Santa Ana National Wildlife Refuge. Other good options in the area include Pharr Executive Inn and Super 8 by Wyndham Hidalgo/McAllen Area.

If I need to cancel the hotel reservation for my stay near Santa Ana National Wildlife Refuge, will I receive a refund?

Yes, most hotel room reservations are refundable if you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of check in. If your reservation is non-refundable, it might still be possible to cancel it and receive a refund within 24 hours of your booking. Plug in your dates, click on "Search", then use the filter option "fully refundable" to review the best deals available near Santa Ana National Wildlife Refuge.

Where can I learn more about changing or cancelling my trip in the area near Santa Ana National Wildlife Refuge?

For more details about updating your stay near Santa Ana National Wildlife Refuge or cancelling it, head over to our customer service page.

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