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Check availability on Santa Ana Business Hotels

Tonight
Sep 14 - Sep 15
Tomorrow
Sep 15 - Sep 16
This weekend
Sep 18 - Sep 20
Next weekend
Sep 25 - Sep 27

Our top choices for Santa Ana business-friendly hotels

A hotel lobby with seating areas, a reception desk, and a large window offering a view of the outside.
A multi-story hotel with a covered entrance, palm trees, and a sign indicating it is a 'Best Western Plus' hotel.
An outdoor patio with tables and chairs, shaded by large umbrellas, and surrounded by palm trees and a hedge.
A pool area with a hot tub, lounge chairs, and a covered grill.

1. Best Western Plus Orange County Airport North

Best Western Plus Orange County Airport North
Santa Ana
United States
Connie
NT$3,445
NT$3,893 total
includes taxes & fees
Sep 27 - Sep 28
Best Western Plus Orange County Airport North
A modern bar area with a wooden counter, orange bar stools, and a flat-screen TV mounted on the wall.
A modern lounge area with a flat-screen TV, a fireplace, and comfortable seating.
A hotel entrance with a prominent sign, palm trees, and a parking lot.
A spacious lobby with a reception desk, seating area, and a staircase leading to upper floors.

2. La Quinta Inn & Suites by Wyndham Orange County Airport

La Quinta Inn & Suites by Wyndham Orange County Airport
Santa Ana
United States
bianca
NT$2,980
NT$3,367 total
includes taxes & fees
Sep 27 - Sep 28
La Quinta Inn & Suites by Wyndham Orange County Airport
A hotel room with a large bed, a desk, a chair, a TV, and a balcony with curtains.
A coffee station with two coffee machines, a coffee press, and various coffee-related items on a counter.
A conference room with tables and chairs, a projector screen, and framed artwork on the walls.
A hotel with a swimming pool, sun loungers, and palm trees.

3. Holiday Inn Express & Suites Santa Ana - Orange County by IHG

Holiday Inn Express & Suites Santa Ana - Orange County by IHG
Lyon Street
United States
Rebecca
NT$3,861
NT$4,370 total
includes taxes & fees
Sep 20 - Sep 21
Holiday Inn Express & Suites Santa Ana - Orange County by IHG

4. Hotel Zessa Orange County Airport, a DoubleTree by Hilton

Hotel Zessa Orange County Airport, a DoubleTree by Hilton
Santa Ana
United States
Astrid
NT$4,126
NT$4,662 total
includes taxes & fees
Oct 2 - Oct 3
Hotel Zessa Orange County Airport, a DoubleTree by Hilton
An outdoor seating area with wicker furniture, a central fire pit, and a pool in the background.
A rooftop pool area with lounge chairs and a fire pit, surrounded by a fence and overlooking a multi-story building.
A spacious lobby with a high ceiling, a reception desk, and seating areas.
A Comfort Inn & Suites with a stone facade, large windows, and a covered entrance area.

5. Comfort Inn & Suites Orange County John Wayne Airport

Comfort Inn & Suites Orange County John Wayne Airport
Santa Ana
United States
Kuoliang
NT$3,220
NT$3,645 total
includes taxes & fees
Oct 4 - Oct 5
Comfort Inn & Suites Orange County John Wayne Airport
A stone fire pit surrounded by palm trees and chairs in an outdoor seating area.
A modern hotel room with a sofa, armchair, ottoman, kitchenette, and a television.
A gift shop with a Pepsi refrigerator, shelves with various items, and a glass display case with knick-knacks.
A spacious interior with a wooden floor, a reception desk, a fireplace, and a dining area with natural light.

6. MainStay Suites John Wayne Airport by Choice Hotels

MainStay Suites John Wayne Airport by Choice Hotels
Santa Ana
United States
JOSEPH
NT$2,932
NT$3,319 total
includes taxes & fees
Sep 21 - Sep 22
MainStay Suites John Wayne Airport by Choice Hotels
A modern hotel with a pool, palm trees, and a parking area.
A cozy outdoor seating area with wicker furniture and a central fire feature.
A television displaying a Courtyard by Marriott hotel with a view of the building's exterior.
A modern bar area with a curved counter, multiple seating options, and a variety of liquor bottles and glasses.

7. Courtyard by Marriott Santa Ana Orange County

Courtyard by Marriott Santa Ana Orange County
Santa Ana
United States
Catalina
NT$3,604
NT$4,080 total
includes taxes & fees
Sep 27 - Sep 28
Courtyard by Marriott Santa Ana Orange County
An outdoor seating area with a circular fire pit surrounded by wicker furniture and a stone fire table.
A refrigerated display case with various beverages and snacks, a sign reading "the market", and a wooden wall with the word "market" in illuminated letters.
A modern bar area with high stools, a counter, and a wine display.
A modern hotel lobby with a sofa, armchairs, a coffee table, and a fireplace.

8. Courtyard by Marriott Costa Mesa South Coast Metro

Courtyard by Marriott Costa Mesa South Coast Metro
Santa Ana
United States
Daniel
NT$4,493
NT$5,101 total
includes taxes & fees
Sep 26 - Sep 27
Courtyard by Marriott Costa Mesa South Coast Metro
A hotel room with a bed, a desk, a chair, a lamp, a TV, and a window with a view of trees.
A snack and beverage vending area with a variety of snacks and drinks.
A pier with a red-roofed building, extending into the ocean with waves crashing against it.
A swimming pool with lounge chairs, a lifeguard tower, and palm trees in the background.

9. Holiday Inn Santa Ana-Orange Co. Arpt by IHG

Holiday Inn Santa Ana-Orange Co. Arpt by IHG
Santa Ana
United States
lakeesha
NT$4,145
NT$4,692 total
includes taxes & fees
Sep 20 - Sep 21
Holiday Inn Santa Ana-Orange Co. Arpt by IHG
An outdoor patio area with tables and chairs, umbrellas, and a view of a water body and buildings.
A modern hotel room with a sofa set, a dining table, and a kitchen area.
A gym with treadmills, weight benches, and a squat rack.
A hotel room with a large bed, a view of high-rise buildings, and a window with curtains.

10. voco Orange County - Airport by IHG

voco Orange County - Airport by IHG
Santa Ana
United States
Gabriela
NT$4,240
NT$4,800 total
includes taxes & fees
Sep 21 - Sep 22
voco Orange County - Airport by IHG
View all properties

Top Santa Ana Hotel Reviews

Best Western Plus Stovall's Inn

Best Western Plus Stovall's Inn

10/10 Excellent
"Clean room, clean gym/pool/spa, nicely maintained garden, good breakfast & within 15 minutes walking from shopping, restaurants, Disney & the Convention. Great place to stay- would do again!"
Amber 1-night trip
Posted less than an hour ago
Best Western Plus Stovall's Inn
Knott's Hotel

Knott's Hotel

10/10 Excellent
"Our stay at the Knott’s Hotel in Anaheim was genuinely wonderful and far exceeded our expectations. The property has a welcoming, family‑friendly atmosphere, and the staff were consistently warm, attentive, and upbeat — the kind of service that makes you feel taken care of from the moment you arrive. One of the highlights was the pool area, which is beautifully maintained and perfect for unwinding after a long day. We especially appreciated the splash pad, a thoughtful touch for small children who aren’t ready for full swimming yet. It made the space feel inclusive for families with kids of all ages and gave little ones a safe place to play. Another pleasant surprise was the parking fee. At $25 per night, it’s noticeably lower than several comparable hotels in the area, which made the stay feel like an even better value. They will schedule a shuttle to Disneyland if you are going and we highly recommend. The only drawback — and it’s minor in the grand scheme — is that the walls are a bit thin. We could hear a baby crying for a few hours one night, which wasn’t ideal, but it didn’t overshadow the overall comfort and quality of the stay. Despite that small issue, the Knott’s Hotel delivered a delightful experience. Clean rooms, great amenities, friendly staff, and family‑centered features it’s great."
Eycleisha 1-night trip
Posted 1 hour ago
Knott's Hotel
The Maya

The Maya

10/10 Excellent
"."
Chiquita 2-night trip
Posted 1 hour ago
The Maya
Clementine Hotel & Suites Anaheim

Clementine Hotel & Suites Anaheim

10/10 Excellent
"It was great stay. Pleasant stay. Great place workers were nice."
Martha 3-night trip
Posted 2 hours ago
Clementine Hotel & Suites Anaheim
Desert Palms Hotel & Suites

Desert Palms Hotel & Suites

10/10 Excellent
"Pleasantly surprised, excellent location- close to convention center and disney parks. The breakfast was nice, and we really enjoyed the variety of rooms offered, including bunks."
Jenna 3-night trip
Posted 2 hours ago
Desert Palms Hotel & Suites
Grand Legacy At the Park

Grand Legacy At the Park

10/10 Excellent
"Clean room. Cold pool. Good ac. What more can you ask for within walking diatance of the convention center and disney"
Gregory 3-night trip
Posted 4 hours ago
Grand Legacy At the Park
Hotel Lulu, BW Premier Collection

Hotel Lulu, BW Premier Collection

8/10 Good
"Great proximity to the parks. Rooms good, clean and had everything I needed. Requested housekeeping for each day in advance and it was great! I did notice that the lobby and common areas felt really run down and not very clean. Rooms felt much better taken care of, so I guess I can't really complain too much! Also, there were three elevators but they were really slow and took a long time to get. Would recommend to families who want to be close to the parks at a good value."
Cori 3-night trip
Posted 7 hours ago
Hotel Lulu, BW Premier Collection
Clarion Hotel Anaheim Resort

Clarion Hotel Anaheim Resort

10/10 Excellent
"Close to the convention center!!"
Christopher 3-night trip
Posted 7 hours ago
Clarion Hotel Anaheim Resort
Sheraton Park Hotel at the Anaheim Resort

Sheraton Park Hotel at the Anaheim Resort

10/10 Excellent
"My family and I stayed at the Sheraton for BlizzCon 2026 and it was a wonderful experience. The room was spacious, the staff was friendly and we truly enjoyed our stay."
Sean 3-night trip
Posted 7 hours ago
Sheraton Park Hotel at the Anaheim Resort

Frequently asked questions

How much do business-friendly hotels in Santa Ana cost?
Prices for business hotels in Santa Ana range between NT$3,319 and NT$5,101 per night. Whatever your budget, Expedia will help you locate the best place to get the job done. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
What are the best business-friendly hotels in Santa Ana?
Select from multiple business-friendly hotels in Santa Ana that have a total average guest review rating of 8.2. Courtyard by Marriott Anaheim Theme Park Entrance is a favorite among corporate travelers. This 3.5-stars property features amenities such as a waterslide and a swimming pool. Ayres Hotel Orange is another highly rated option. It has a 3.5-stars rating and conveniences including a swimming pool and an electric car charging station.
How many business-friendly hotels are there in Santa Ana?
Santa Ana offers 17 hotels that accommodate corporate travelers. Whether you're looking for a location closer to the city or amenities like conference rooms and dependable WiFi, you'll find a well-suited property on Expedia.
What are the best cheap business-friendly hotels in Santa Ana?
Business-friendly hotels in Santa Ana start at NT$3,319 per night, so your work-related trip doesn't have to cost a lot. Best Western Plus Anaheim Inn is a reasonably priced choice that comes with plenty of amenities, like a terrace and a swimming pool. Holiday Inn Express & Suites Anaheim Resort Area, an IHG Hotel is another cheap stay that's favored by corporate guests. Conveniences here include a memory foam mattress and an electric car charging station. When you're ready to see the sights of Santa Ana, add a few free attractions to your work trip agenda. Old Orange County Courthouse and Jack & Shanaz Langson Institute & Museum of California Art are favorites. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
What are the top business-friendly motels in Santa Ana?
Motel 6 Anaheim Hills is a popular choice, located around 14 kilometers northeast of downtown Santa Ana. Featuring a steam room and a swimming pool, this business-friendly motel has the amenities you need to work and play. Motel 6 Irvine - Orange County Airport also caters to corporate travelers. It's approximately 5 kilometers south of central Santa Ana and includes a swimming pool, a spa tub and more.With lots of shopping, cultural and dining options to discover, you might consider extending your corporate trip to Santa Ana. Disneyland® Resort and Disney California Adventure® Park are terrific places to kick off your sightseeing adventures.
Are there any family-friendly hotels in Santa Ana that are also business friendly?
Courtyard by Marriott Anaheim Theme Park Entrance is popular with both leisure and corporate guests. A waterslide and a nearby theme park are just two of the amenities offered at this 3.5-stars Santa Ana stay. Alternatively, vacation with the fam and work on the road at Ayres Hotel Orange. You'll have use of conveniences like complimentary breakfast and a nearby theme park at this leading 3.5-stars option. Once work is out of the way, there are lots of family-friendly attractions to see around Santa Ana. Disneyland® Resort and Disney California Adventure® Park are two of our top picks.
Are there any 5-star business-friendly hotels in Santa Ana?
Santa Ana doesn't have any 5-star business-friendly hotels — but there are still some upmarket accommodations where you can base yourself for work. Why not book Avenue of the Arts Costa Mesa, a Tribute Portfolio Hotel? Around 6 kilometers from downtown, this 4-star favorite comes with nice extras like a spa tub and a sauna. DoubleTree Suites by Hilton Anaheim Rsrt - Conv Cntr is another fantastic choice for busy business types, and is located just 6 kilometers from central Santa Ana. Also with a 4-star rating, it features amenities such as proposal/romance packages and a spa tub.
Why book your business-friendly hotel in Santa Ana with Expedia?
Expedia will help you find an ideal business-friendly hotel for your upcoming work trip. From free WiFi and parking to on-site restaurants and more, our stays have all the amenities you'll need to close that big deal.
How can I find cheap business-friendly hotels in Santa Ana?
When work takes you to Santa Ana, our "business friendly" filter will help you find a suitable hotel. From free WiFi and included breakfast to concierge services and conference spaces, they come with the amenities you need for a comfortable and productive stay. You can also refine your search by your preferred star rating and budget to see the most affordable properties.
What is there to do in Santa Ana near my business-friendly hotel?
Santa Ana has enough experiences and activities to keep you going for weeks, beginning with Disneyland® Resort. Disney California Adventure® Park, Segerstrom Center for the Arts and Santa Ana Zoo are other awesome attractions. If your business trip gives you time to spare, Adventure City and Great Wolf Lodge Water Park will add the finishing touches to your itinerary.

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