The Best Business Hotels in Santa Ana, CA from NT$3,324 in 2026

A large military aircraft on a tarmac with a city skyline in the background.

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Check availability on Santa Ana Business Hotels

Tonight

Tomorrow

This weekend

Next weekend

Our top choices for Santa Ana business-friendly hotels

1. Holiday Inn Express & Suites Santa Ana - Orange County by IHG

Lyon Street

Rebecca

NT$3,614

NT$4,090 total

includes taxes & fees

Sep 27 - Sep 28

2. Best Western Plus Orange County Airport North

Santa Ana

Keith

NT$3,452

NT$3,900 total

includes taxes & fees

Aug 31 - Sep 1

3. La Quinta Inn & Suites by Wyndham Orange County Airport

Santa Ana

NT$3,040

NT$3,436 total

includes taxes & fees

Aug 31 - Sep 1

4. Comfort Inn & Suites Orange County John Wayne Airport

Santa Ana

Dr. Lindokuhle

NT$3,242

NT$3,670 total

includes taxes & fees

Sep 20 - Sep 21

5. Hotel Zessa Orange County Airport, a DoubleTree by Hilton

Santa Ana

Judith

NT$3,627

NT$4,099 total

includes taxes & fees

Sep 6 - Sep 7

Suite, 1 King Bed, Non Smoking, Pool View

6. MainStay Suites John Wayne Airport by Choice Hotels

Santa Ana

MICHAEL

NT$2,937

NT$3,324 total

includes taxes & fees

Sep 21 - Sep 22

Standard Room, 1 King Bed, Pool Access | View from room

7. Holiday Inn Santa Ana-Orange Co. Arpt by IHG

Santa Ana

lakeesha

NT$4,248

NT$4,808 total

includes taxes & fees

Aug 30 - Aug 31

8. Courtyard by Marriott Santa Ana Orange County

Santa Ana

Cynthia

NT$3,823

NT$4,327 total

includes taxes & fees

Sep 27 - Sep 28

View all properties

Top Santa Ana Hotel Reviews

Clementine Hotel & Suites Anaheim

8/10 Good

"The one drawback to our stay was the cleanliness of the room. I noted other people’s hair, eyelashes, and sand-like particles throughout the top of the fitted sheet. This instantly made me significantly concerned as to what I had potentially exposed my son and I to. Additionally, there was strands of long black hair in our bath tub that just added to my concern in regard to the cleanliness of our room and although the amenities were great and the staff was wonderful and the location was close enough to walk, these components of uncleanliness placed a real damper in my opinion of the hotel and unfortunately, I don’t know if I could in good faith ever book another stay at this hotel."

Motel 6 Anaheim Maingate

10/10 Excellent

"awesome would stay again"

The Anaheim Hotel

10/10 Excellent

"Staff was super helpful + location was convenient ! Would stay again!"

Best Western Plus Stovall's Inn

10/10 Excellent

"Great staff, very convenient location"

Frequently asked questions

How much do business-friendly hotels in Santa Ana cost?

Prices for business hotels in Santa Ana range between NT$3,324 and NT$4,808 per night. Whatever your budget, Expedia will help you locate the best place to get the job done. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.

What are the best business-friendly hotels in Santa Ana?

Select from multiple business-friendly hotels in Santa Ana that have a total average guest review rating of 8.2. Courtyard by Marriott Anaheim Theme Park Entrance is a favorite among corporate travelers. This 3.5-stars property features amenities such as a waterslide and a swimming pool. Ayres Hotel Orange is another highly rated option. It has a 3.5-stars rating and conveniences including a swimming pool and an electric car charging station.

How many business-friendly hotels are there in Santa Ana?

Santa Ana offers 17 hotels that accommodate corporate travelers. Whether you're looking for a location closer to the city or amenities like conference rooms and dependable WiFi, you'll find a well-suited property on Expedia.

What are the best cheap business-friendly hotels in Santa Ana?

Business-friendly hotels in Santa Ana start at NT$3,324 per night, so your work-related trip doesn't have to cost a lot. Best Western Plus Anaheim Inn is a reasonably priced choice that comes with plenty of amenities, like a terrace and a swimming pool. Holiday Inn Express & Suites Anaheim Resort Area, an IHG Hotel is another cheap stay that's favored by corporate guests. Conveniences here include a memory foam mattress and an electric car charging station. When you're ready to see the sights of Santa Ana, add a few free attractions to your work trip agenda. Old Orange County Courthouse and Jack & Shanaz Langson Institute & Museum of California Art are favorites. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.

What are the top business-friendly motels in Santa Ana?

Motel 6 Anaheim Hills is a popular choice, located around 14 kilometers northeast of downtown Santa Ana. Featuring a steam room and a swimming pool, this business-friendly motel has the amenities you need to work and play. Motel 6 Irvine - Orange County Airport also caters to corporate travelers. It's approximately 5 kilometers south of central Santa Ana and includes a swimming pool, a spa tub and more.With lots of shopping, cultural and dining options to discover, you might consider extending your corporate trip to Santa Ana. Disneyland® Resort and Disney California Adventure® Park are terrific places to kick off your sightseeing adventures.

Are there any family-friendly hotels in Santa Ana that are also business friendly?

Courtyard by Marriott Anaheim Theme Park Entrance is popular with both leisure and corporate guests. A waterslide and a nearby theme park are just two of the amenities offered at this 3.5-stars Santa Ana stay. Alternatively, vacation with the fam and work on the road at Ayres Hotel Orange. You'll have use of conveniences like complimentary breakfast and a nearby theme park at this leading 3.5-stars option. Once work is out of the way, there are lots of family-friendly attractions to see around Santa Ana. Disneyland® Resort and Disney California Adventure® Park are two of our top picks.

Are there any 5-star business-friendly hotels in Santa Ana?

Santa Ana doesn't have any 5-star business-friendly hotels — but there are still some upmarket accommodations where you can base yourself for work. Why not book Avenue of the Arts Costa Mesa, a Tribute Portfolio Hotel? Around 6 kilometers from downtown, this 4-star favorite comes with nice extras like a spa tub and a sauna. DoubleTree Suites by Hilton Anaheim Rsrt - Conv Cntr is another fantastic choice for busy business types, and is located just 6 kilometers from central Santa Ana. Also with a 4-star rating, it features amenities such as proposal/romance packages and a spa tub.

Why book your business-friendly hotel in Santa Ana with Expedia?

Expedia will help you find an ideal business-friendly hotel for your upcoming work trip. From free WiFi and parking to on-site restaurants and more, our stays have all the amenities you'll need to close that big deal.

How can I find cheap business-friendly hotels in Santa Ana?

When work takes you to Santa Ana, our "business friendly" filter will help you find a suitable hotel. From free WiFi and included breakfast to concierge services and conference spaces, they come with the amenities you need for a comfortable and productive stay. You can also refine your search by your preferred star rating and budget to see the most affordable properties.

What is there to do in Santa Ana near my business-friendly hotel?

Santa Ana has enough experiences and activities to keep you going for weeks, beginning with Disneyland® Resort. Disney California Adventure® Park, Segerstrom Center for the Arts and Santa Ana Zoo are other awesome attractions. If your business trip gives you time to spare, Adventure City and Great Wolf Lodge Water Park will add the finishing touches to your itinerary.

Explore a world of travel with Expedia

Book Business Hotels in Santa Ana on Expedia.com

Room 1

Change your mind

Treat yourself

Be picky

Check availability on Santa Ana Business Hotels

Our top choices for Santa Ana business-friendly hotels

1. Holiday Inn Express & Suites Santa Ana - Orange County by IHG

2. Best Western Plus Orange County Airport North

3. La Quinta Inn & Suites by Wyndham Orange County Airport

4. Comfort Inn & Suites Orange County John Wayne Airport

5. Hotel Zessa Orange County Airport, a DoubleTree by Hilton

6. MainStay Suites John Wayne Airport by Choice Hotels

7. Holiday Inn Santa Ana-Orange Co. Arpt by IHG

8. Courtyard by Marriott Santa Ana Orange County

9. Embassy Suites by Hilton Santa Ana Orange County Airport

10. Courtyard by Marriott Costa Mesa South Coast Metro