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Compare 3,396 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

I Borghi dell'Eremo

Piegaro
10.0 out of 10, Exceptional, (54)
"Beautiful grounds, room:suites, impeccable staff made a wonderful relaxing time but still have our favorite small villages to explore "
United States
Donna
The price is NT$10,548
NT$11,602 total
includes taxes & fees
Dec 10 - Dec 11
I Borghi dell'Eremo

Asisium Boutique Hotel

4.0 star property
Assisi Historic Center
9.2 out of 10, Wonderful, (127)
"Very modern and up to date with comfortable bed and large shower with excellent water pressure"
United States
Adam
The price is NT$4,441
NT$5,103 total
includes taxes & fees
Jan 9 - 2026/1/10
Asisium Boutique Hotel

Camere Santa Chiara

Assisi Historic Center
10.0 out of 10, Exceptional, (4)
"Very friendly staff. Location was great with easy access to all the sites, restaurants and coffee. Breakfast was located in another building and it was easy to find. "
United States
Elisa
The price is NT$3,201
NT$3,666 total
includes taxes & fees
Jan 7 - 2026/1/8
Camere Santa Chiara

Hotel Ristorante La Terrazza

3.0 star property
Assisi Historic Center
9.2 out of 10, Wonderful, (258)
"Quiet spot"
Canada
David
The price is NT$3,637
NT$4,146 total
includes taxes & fees
Dec 10 - Dec 11
Hotel Ristorante La Terrazza

Giotto Hotel & Spa

4.0 star property
Assisi Historic Center
8.8 out of 10, Excellent, (761)
"Very relaxing & restful hotel "
United States
Mary Davis
Giotto Hotel & Spa

Hotel Sorella Luna

3.0 star property
Assisi Historic Center
9.4 out of 10, Exceptional, (255)
"Centrally located hotel with friendly staff, great accommodation and wonderful breakfast."
United States
Alex
The price is NT$3,639
NT$4,149 total
includes taxes & fees
Dec 14 - Dec 15
Hotel Sorella Luna

TH Assisi - Hotel Cenacolo

4.0 star property
Assisi
9.2 out of 10, Wonderful, (609)
"Nice place to stay"
United States
José Felipe Casillas
The price is NT$2,393
NT$2,851 total
includes taxes & fees
Jan 6 - 2026/1/7
TH Assisi - Hotel Cenacolo

Il Palazzo

3.0 star property
Assisi Historic Center
9.6 out of 10, Exceptional, (463)
"Great and friendly staff. Good location. Good breakfast. Great clean room. Incredible views from the room."
Canada
Xavier
Il Palazzo

Dal Moro Gallery Hotel

4.0 star property
Assisi
9.0 out of 10, Wonderful, (213)
"Great location"
United States
Maria Theresa
The price is NT$3,601
NT$4,179 total
includes taxes & fees
Dec 17 - Dec 18
Dal Moro Gallery Hotel

Windsor Savoia

3.0 star property
Assisi
9.0 out of 10, Wonderful, (90)
"Great location, clean, spacious rooms."
United States
LUZ
The price is NT$4,146
NT$4,706 total
includes taxes & fees
Dec 10 - Dec 11
Windsor Savoia

Hotel Ristorante La Bastiglia

4.0 star property
Spello
8.0 out of 10, Very Good, (79)
"Clean rooms great views. Make sure you check in early since a parking permit is necessary. "
United States
Gennaro
The price is NT$2,410
NT$2,906 total
includes taxes & fees
Dec 10 - Dec 11
Hotel Ristorante La Bastiglia

Cittadella Ospitalità

Assisi Historic Center
8.0 out of 10, Very Good, (286)
"Outstanding stay. Quiet, relaxing, and within walking distance of all the major attractions in the old part of Assisi."
United States
Jeffery
Cittadella Ospitalità

Hotel Porta Nuova

3.0 star property
Assisi Historic Center
9.2 out of 10, Wonderful, (388)
"Great stay and nice breakfast"
United States
Joseph
The price is NT$2,546
NT$2,946 total
includes taxes & fees
Dec 11 - Dec 12
Hotel Porta Nuova

Hotel Monastero Sant'Andrea

Assisi Historic Center
9.6 out of 10, Exceptional, (37)
"Very nice place to stay "
United States
maria m
The price is NT$2,553
NT$2,954 total
includes taxes & fees
Dec 16 - Dec 17
Hotel Monastero Sant'Andrea

Da Angelo

Assisi Historic Center
8.8 out of 10, Excellent, (87)
"Basic hotel and good for venturing to Assisi "
United Kingdom
gaurang
Da Angelo

Il Giardino degli Angeli

Assisi
9.6 out of 10, Exceptional, (59)
"We were treated like family by the outgoing and friendly hosts at Il Giardino degli Angeli. Suggestions for day trips and local sites to visit were offered and appreciated. The rooms were clean and spacious. Breakfast was wonderful!"
Canada
Jeremy
The price is NT$3,042
NT$3,492 total
includes taxes & fees
Dec 10 - Dec 11
Il Giardino degli Angeli

Portica 10

Assisi Historic Center
10.0 out of 10, Exceptional, (104)
"Very clean room, super helpful hosts, and a wonderful breakfast, too e truly felt at home! "
United States
Mark
The price is NT$3,869
NT$4,401 total
includes taxes & fees
Dec 10 - Dec 11
Portica 10

Il Castello

Assisi
9.0 out of 10, Wonderful, (34)
"One of the nicest places we ww have ever stayed. The dinner was amazing, thank you Mama, and the views spectacular. We will be back."
United States
David
The price is NT$2,299
NT$2,674 total
includes taxes & fees
Dec 10 - Dec 11
Il Castello

Hotel Fontebella

4.0 star property
Assisi Historic Center
8.6 out of 10, Excellent, (631)
"Fantastic views and staff"
United States
Nancy
Hotel Fontebella

Hotel Pax

3.0 star property
Assisi Historic Center
9.2 out of 10, Wonderful, (221)
"Great location. Very friendly and helpful staff. "
United States
Gregory
The price is NT$3,009
NT$3,455 total
includes taxes & fees
Dec 16 - Dec 17
Hotel Pax
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Where is the best place to stay in San Sisto?
La Meridiana Bleisure Hotel, located 1.1 mi (1.7 km) from the heart of San Sisto, is a top choice for your stay based on our traveler data. Two other choices for your visit to the area are TH Assisi - Hotel Cenacolo and Giotto Hotel & Spa. See all available top hotels, or vacation rentals in San Sisto.
What are some of the best vacation home rentals that San Sisto has to offer?
Country House Le Case Coloniche: This vacation home rental outside of San Sisto is located in a rural location and has a terrace, a garden, and a barbecue grill to put you at ease in your new surroundings. This vacation rental also comes with free parking to give you added peace of mind. See all vacation rentals in San Sisto.
If I need to cancel my hotel reservation in San Sisto, will I receive a refund?
Yes, the majority of hotel bookings are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you have a non-refundable reservation, you might still have the option to cancel and be given a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in San Sisto.
Where can I learn more about changing or cancelling my trip to San Sisto?
For more details about picking new dates or cancelling your trip to San Sisto, head over to our customer service page.
What are some hotels with pools in San Sisto?
La Meridiana Bleisure Hotel: Features a children's pool, a seasonal outdoor pool, and a rooftop terrace. Hotel Sangallo Palace and Sina Brufani are two additional hotels that offer an onsite pool. View all hotels with pools in San Sisto.
What is the best accommodation for staying close to Falconara Airport (AOI)?
Hotel Touring Falconara Marittima is one of the top choices for your stay and is a popular 3-star hotel featuring a roundtrip airport shuttle and an airport shuttle. It's located 2.7 mi (4.3 km) from Falconara Airport. Other choices near the airport include Residenza Leonardo and Tenuta Villa Colle Sereno.
What is staying in San Sisto like?
Those traveling to San Sisto are sure to enjoy the sights to see and things to do. In San Sisto, there are 6 hotels and other accommodations to choose from. Find out more about San Sisto.
What should I do while I'm visiting San Sisto?
A favorite place to visit is Perugina Chocolate Factory. You'll also find Renato Curi Stadium and Citta della Domenica in the area. Check out what more to see and do in Expedia's San Sisto guide.
What's the best way to get around San Sisto?
To see more of the larger area, hop on a train at Perugia Silvestrini Station. If you want to venture out around the area, you may want a rental car in San Sisto for your journey.
What's the seasonal weather like in San Sisto?
The hottest months are usually August and July with an average temp of 72°F, while the coldest months are January and February with an average of 44°F. Average annual precipitation for San Sisto is 37 inches.

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