Find Luxury Hotels in San Luis, FL

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check availability on San Luis Luxury Hotels

Next weekend
In two weeks

Top San Luis Luxury Hotels

Frequently asked questions

Are you searching for a great accommodation for your luxury getaway to San Luis?
Use Expedia to arrange your flight to Tallahassee Intl. Airport (TLH) airport, and then choose from a variety of places to stay that will deliver the luxury you seek. Amenities are an important consideration when you plan a trip, so we make it easy to get what you want to make your stay special. If you want a posh hotel with fine dining, a spa, or several swimming pools, Expedia can help you find the best luxury hotel experience that San Luis offers.
What's the best time to vacation in San Luis?
The hottest months are usually July and August with an average temperature of 80°F,
  • Coldest months: January, February, December, and November
  • Driest months: October, November, May, and February
  • Rainiest months: July, June, August, and September
What's there to see and do in San Luis?
Enjoy all that San Luis has to offer and visit Mission San Luis de Apalachee, Bobby Bowden Field at Doak Campbell Stadium, and The Centre of Tallahassee. If you have a bit of extra time while you're in the area, you might want to check out Donald L. Tucker Civic Center and Lake Ella Park.