Otay Mesa, CA
San Diego
Visit Otay Mesa
Stay near popular Otay Mesa attractions
Otay Mesa Hotel Deals
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
"Happy with are stay"
Reviewed on 2026/8/11
Paradise Point Resort & Spa
"Waterfall pool was not clean"
Reviewed on 2026/8/12
Manchester Grand Hyatt San Diego
"Don’t book here at all. I booked this place for a honeymoon and a nice room, only to be told on day of arrival that"
Reviewed on 2026/8/12
Wyndham San Diego Bayside
"The view was perfect"
Reviewed on 2026/8/12
The Dana on Mission Bay
"It was a very nice place to stay for a couple of days. Very close to lots to do. You can catch an Uber or drive because it was central to lots of things. I would recommend this place. One downfall is having to pay for parking. That is my only complaint and wish I had seen that but because I reserved ..."
Reviewed on 2026/8/12
Hard Rock Hotel San Diego
Where to stay in Otay Mesa
Downtown San Diego
Petco Park and Port of San Diego are a few top attractions in Downtown San Diego. Hop around the city on the metro at Civic Center Station or Civic Center Station and check out the area's fantastic nightlife, fascinating museums, and beautiful waterfront views.
Pacific Beach
The stunning beaches and fantastic nightlife are just a few highlights of Pacific Beach. Make a stop by Mission Bay or Pacific Beach while you're exploring the area.
Mission Beach
If you're spending some time in Mission Beach, Mission Beach and Mission Bay are top sights worth seeing.
Gaslamp Quarter
Fantastic nightlife and popular shops are a few of the things travelers enjoy most about Gaslamp Quarter. A visit to Gaslamp Museum at the Davis-Horton House or Nova SD is also recommended, and you can jump aboard the metro at Gaslamp Quarter Station to get around town.
Mission Bay
If you're spending some time in Mission Bay, Mission Bay and Mission and Pacific Beaches are top sights worth seeing.
