Otay Mesa, CA
San Diego
Visit Otay Mesa
Popular places to visit
San Diego Zoo
See nature up-close and personal at one of the country’s largest and most educational zoos.
San Diego Convention Center
During your trip, find out what's happening at San Diego Convention Center, a top convention center in San Diego. Experience the area's fascinating museums and entertainment choices.
Mission Bay
Mingle with eccentric locals at bohemian beaches, soak up the sun on a Jet Ski and fish from marshy islands at San Diego’s premier water park.
SeaWorld
Animal interaction, entertaining rides and informative exhibits are all on offer at this family favorite destination.
Petco Park
Purchase a hot dog and watch the San Diego Padres, California’s southernmost Major League Baseball team, play on their home field.
Mission Beach
A favorite vacation spot for 100 years, this seaside village combines old-fashioned charm with modern amenities.
Otay Mesa Hotel Deals
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
"We weren't sure about location but turned out to be terrific and quiet and safe"
Reviewed on 2026/6/21
Manchester Grand Hyatt San Diego
"Room was spacious and beautiful and quiet. The bed was super comfortable. The only problem and the reason I only give the hotel 4 stars was because there was no safety bar in the bathroom. For a senior citizen such as myself this is a real need when stepping high out of a bathroom tub. Sort of strange ..."
Reviewed on 2026/6/21
Paradise Point Resort & Spa
"Paradise Point has a beautiful property and grounds, and the main pool was a lot of fun for our family. The island-style atmosphere is unique and relaxing, and the location is convenient for visiting San Diego attractions. That said, for the price, I expected a bit more. Complimentary breakfast would ..."
Reviewed on 2026/6/21
Wyndham San Diego Bayside
"The room itself was a little worn with wear and tear, it could use a refresh. That aside the room was very comfortable and clean. The location to everything was excellent, and with the bay view rooms you couldnt beat the view. I did not interact with anyone except at check in, and I wish I remembered ..."
Reviewed on 2026/6/21
Hard Rock Hotel San Diego
"The Gas Lamp area is fantastic and the hotel is close by so many great restaurants and attractions. The light rail is right across the street which is a great option for inner city connections."
Reviewed on 2026/6/21
Bahia Resort Hotel
"We like the property, but the beach in the bay is really not swimmable, it was great. We were walking distance to Mission Beach, which was beautiful. Very difficult to get a reservation or a table at the pizza restaurant. The hotel itself was very well-maintained and we will definitely stay ..."
Reviewed on 2026/6/21
Where to stay in Otay Mesa
Downtown San Diego
Petco Park and Port of San Diego are a few top attractions in Downtown San Diego. Hop around the city on the metro at Civic Center Station or Civic Center Station and check out the area's fantastic nightlife, fascinating museums, and beautiful waterfront views.
Pacific Beach
The stunning beaches and fantastic nightlife are just a few highlights of Pacific Beach. Make a stop by Mission Bay or Pacific Beach while you're exploring the area.
Mission Beach
If you're spending some time in Mission Beach, Mission Beach and Mission Bay are top sights worth seeing.
Gaslamp Quarter
Fantastic nightlife and popular shops are a few of the things travelers enjoy most about Gaslamp Quarter. A visit to Gaslamp Museum at the Davis-Horton House or Lyceum Theatre is also recommended, and you can jump aboard the metro at Gaslamp Quarter Station to get around town.
Mission Bay
If you're spending some time in Mission Bay, Mission Bay and Ski Beach are top sights worth seeing.
