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Compare hotels close to Roper St. Francis Mount Pleasant Hospital with room rates, reviews, and availability. Most hotels are fully refundable.

Exterior detail
Post House Inn

Post House Inn

3.5 star property
Old Village Historical District, 14.2 km from Roper St. Francis Mount Pleasant Hospital
10.0 out of 10, Exceptional, (63)
"We loved our stay at the Inn! "
United States
Jennifer
Post House Inn
Lobby sitting area
Cambria Hotel Mount Pleasant – Charleston

Cambria Hotel Mount Pleasant – Charleston

3.0 star property
9.8 km from Roper St. Francis Mount Pleasant Hospital
9.4 out of 10, Exceptional, (1786)
"Nice hotel for the price"
United States
James
The price is NT$2,908
NT$3,355 total
includes taxes & fees
Dec 21 - Dec 22
Cambria Hotel Mount Pleasant – Charleston
Rooftop terrace
The Loutrel

The Loutrel

4.0 star property
18.4 km from Roper St. Francis Mount Pleasant Hospital
10.0 out of 10, Exceptional, (1012)
"Beautiful hotel in a great location "
United States
Sean
The Loutrel
Front of property
French Quarter Inn

French Quarter Inn

4.0 star property
18.5 km from Roper St. Francis Mount Pleasant Hospital
10.0 out of 10, Exceptional, (1016)
"Phenomenal stay - highly recommend"
United States
Patricia
French Quarter Inn
Reception
Tru by Hilton Mt Pleasant Charleston

Tru by Hilton Mt Pleasant Charleston

2.5 star property
9.4 km from Roper St. Francis Mount Pleasant Hospital
9.2 out of 10, Wonderful, (1467)
"Front desk staff was amazing "
United States
Denise
The price is NT$2,486
NT$2,872 total
includes taxes & fees
Dec 21 - Dec 22
Tru by Hilton Mt Pleasant Charleston
Frette Italian sheets, premium bedding, pillowtop beds, in-room safe
86 Cannon Charleston - Adults Only

86 Cannon Charleston - Adults Only

4.5 star property
19.2 km from Roper St. Francis Mount Pleasant Hospital
10.0 out of 10, Exceptional, (72)
"The perfect place to stay if your visiting Charleston "
United States
Stephanie
The price is NT$11,877
NT$13,540 total
includes taxes & fees
Dec 7 - Dec 8
86 Cannon Charleston - Adults Only
View from property
HarbourView Inn

HarbourView Inn

4.0 star property
18.3 km from Roper St. Francis Mount Pleasant Hospital
9.8 out of 10, Exceptional, (1007)
"Room was very clean, location perfect. "
United States
Sandra
HarbourView Inn
Microwave, coffee/tea maker, highchair, blender
Hilton Club Liberty Place Charleston

Hilton Club Liberty Place Charleston

3.5 star property
18 km from Roper St. Francis Mount Pleasant Hospital
9.8 out of 10, Exceptional, (879)
"Staff was friendly very clean really nice place "
United States
Salvatore
The price is NT$6,679
NT$7,614 total
includes taxes & fees
Dec 10 - Dec 11
Hilton Club Liberty Place Charleston
Exterior
The Iris Charleston

The Iris Charleston

3.0 star property
18.8 km from Roper St. Francis Mount Pleasant Hospital
9.8 out of 10, Exceptional, (120)
"Clean room and well located"
United States
Stephen
The price is NT$2,944
NT$5,504 total
includes taxes & fees
Dec 7 - Dec 8
The Iris Charleston
Front of property
The Spectator Hotel

The Spectator Hotel

4.0 star property
18.4 km from Roper St. Francis Mount Pleasant Hospital
9.8 out of 10, Exceptional, (978)
"Excellent 5 star hotel"
United States
John
The Spectator Hotel
Free daily on-the-go breakfast
Holiday Inn Express & Suites Charleston NE Mt Pleasant US17 by IHG

Holiday Inn Express & Suites Charleston NE Mt Pleasant US17 by IHG

2.5 star property
6.7 km from Roper St. Francis Mount Pleasant Hospital
9.0 out of 10, Wonderful, (1005)
"Everything about my stay here has been a delight, clean room, professional & friendly staff "
United States
John
The price is NT$2,988
NT$3,377 total
includes taxes & fees
Dec 17 - Dec 18
Holiday Inn Express & Suites Charleston NE Mt Pleasant US17 by IHG
Lobby
Hyatt House Charleston / Mount Pleasant

Hyatt House Charleston / Mount Pleasant

3.5 star property
9.8 km from Roper St. Francis Mount Pleasant Hospital
9.2 out of 10, Wonderful, (1007)
"Room was clean, staff was friendly and helpful and location was great."
United States
Denise
The price is NT$3,442
NT$3,960 total
includes taxes & fees
Jan 2 - 2026/1/3
Hyatt House Charleston / Mount Pleasant
Anson Suite | Frette Italian sheets, premium bedding, Tempur-Pedic beds, in-room safe
Zero George Street

Zero George Street

5.0 star property
18.1 km from Roper St. Francis Mount Pleasant Hospital
9.8 out of 10, Exceptional, (353)
"A delightful stay in a delightful setting. "
United States
Tommy
The price is NT$9,872
NT$11,397 total
includes taxes & fees
Dec 9 - Dec 10
Zero George Street
Terrace/patio
The Pinch Hotel

The Pinch Hotel

4.0 star property
18.6 km from Roper St. Francis Mount Pleasant Hospital
9.8 out of 10, Exceptional, (170)
"Large room with great city views. Well stocked mini bar. Front desk was very friendly and helpful. Great location."
United States
Paul
The Pinch Hotel
Terrace/patio
The Nickel Hotel

The Nickel Hotel

4.0 star property
18.6 km from Roper St. Francis Mount Pleasant Hospital
9.8 out of 10, Exceptional, (76)
"Everything about this new hotel is spot on-elegant design and a sweet and attentive staff within a private refuge-despite an often busy central downtown location."
United States
Christine
The price is NT$8,260
NT$9,483 total
includes taxes & fees
Jan 1 - 2026/1/2
The Nickel Hotel
Courtyard
Hampton Inn & Suites Charleston/Mt. Pleasant-Isle Of Palms

Hampton Inn & Suites Charleston/Mt. Pleasant-Isle Of Palms

2.5 star property
7.3 km from Roper St. Francis Mount Pleasant Hospital
9.0 out of 10, Wonderful, (1002)
"Great place to stay!!!"
United States
Fredrick
The price is NT$2,766
NT$3,192 total
includes taxes & fees
Dec 10 - Dec 11
Hampton Inn & Suites Charleston/Mt. Pleasant-Isle Of Palms
Exterior
Home2 Suites by Hilton Charleston Daniel Island

Home2 Suites by Hilton Charleston Daniel Island

3.0 star property
13.5 km from Roper St. Francis Mount Pleasant Hospital
9.4 out of 10, Exceptional, (499)
"Very clean and excellent staff"
United States
Ronald
The price is NT$3,746
NT$4,271 total
includes taxes & fees
Dec 14 - Dec 15
Home2 Suites by Hilton Charleston Daniel Island
Front of property
20 South Battery

20 South Battery

3.0 star property
19.2 km from Roper St. Francis Mount Pleasant Hospital
9.8 out of 10, Exceptional, (224)
"This stunning property offers excellent amenities and stellar customer service."
United States
Lori
The price is NT$9,295
NT$11,987 total
includes taxes & fees
Dec 3 - Dec 4
20 South Battery
Reception
DoubleTree by Hilton Charleston Mount Pleasant

DoubleTree by Hilton Charleston Mount Pleasant

4.0 star property
10.7 km from Roper St. Francis Mount Pleasant Hospital
9.2 out of 10, Wonderful, (1013)
"Room was nice and staff was very friendly."
United States
Viorel
The price is NT$2,780
NT$3,204 total
includes taxes & fees
Dec 21 - Dec 22
DoubleTree by Hilton Charleston Mount Pleasant
Exterior
Staybridge Suites Charleston - Mount Pleasant by IHG

Staybridge Suites Charleston - Mount Pleasant by IHG

3.0 star property
14.6 km from Roper St. Francis Mount Pleasant Hospital
9.4 out of 10, Exceptional, (1007)
"Great location"
United States
David John
The price is NT$3,616
NT$4,155 total
includes taxes & fees
Dec 21 - Dec 22
Staybridge Suites Charleston - Mount Pleasant by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Roper St. Francis Mount Pleasant Hospital Hotel Reviews

Wild Dunes Resort – Sweetgrass Inn and Boardwalk Inn

Wild Dunes Resort – Sweetgrass Inn and Boardwalk Inn

10/10 Excellent
"Clean room, excellent facility, perfect location "
Jim 1-night trip
Posted 3 days ago
Wild Dunes Resort – Sweetgrass Inn and Boardwalk Inn

Hotels near other Roper St. Francis Mount Pleasant Hospital attractions

Boone Hall Plantation and Gardens

4.6/5 (518 reviews)
Find out about the history of Mount Pleasant when you take a trip to Boone Hall Plantation and Gardens. Stroll along the area's seaside, or simply savor its lively bars.
See properties

Charleston National Golf Club

5.0/5 (1 review)
Enjoy a round of golf in Mount Pleasant at Charleston National Golf Club. Check out the lively bars or top-notch restaurants in this walkable area.
See properties

Frequently asked questions

What's the area like around Roper St. Francis Mount Pleasant Hospital?
Roper St. Francis Mount Pleasant Hospital is located in Mount Pleasant. This historic area is known for its beautiful river views and array of dining options. You'll find 67 hotels and other accommodations within a few miles for a convenient home base.
What's the best place to stay near Roper St. Francis Mount Pleasant Hospital?
Holiday Inn Express & Suites Charleston NE Mt Pleasant US17 by IHG is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and free parking. It's located 4.1 mi (6.7 km) from Roper St. Francis Mount Pleasant Hospital. Other good options within a few miles include Comfort Suites at Isle Of Palms Connector and Residence Inn by Marriott Charleston Mount Pleasant.
How many hotels will I find near Roper St. Francis Mount Pleasant Hospital?
Expedia has 67 hotels and other accommodations a few miles from Roper St. Francis Mount Pleasant Hospital.
If I need to cancel the hotel reservation for my stay near Roper St. Francis Mount Pleasant Hospital, will I receive a refund?
Yes! You'll find that most hotel room reservations are refundable provided that you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a reservation that's non-refundable, it may still be possible to cancel it and be given a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to review the best options available near Roper St. Francis Mount Pleasant Hospital.
Where can I learn more about changing or cancelling my trip in the area near Roper St. Francis Mount Pleasant Hospital?
To access more information about updating your stay near Roper St. Francis Mount Pleasant Hospital or cancelling it, head over to our customer service page.
What can I see and do near Roper St. Francis Mount Pleasant Hospital?
You can enjoy nature at Goat Island, Dewees Island Beach, or Palmetto Islands County Park. Dunes West Golf and River Club, Charleston National Golf Club, or Charleston Fun Park are some local sights worth checking out. If you want to see more of the surrounding area, you can plan a visit to Mount Pleasant Towne Centre and Blackbeard's Cove Family Fun Park.

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