Domus 21 Luxury Suites

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Luxury
VIP Access
9.6

Exceptional

Historic luxury in central Rome

Fresco-adorned ceilings crown spacious, quiet rooms in this historic Roman building. Steps from the Pantheon and Trevi Fountain, guests stroll to iconic monuments before returning to luxurious rainfall showers. Attentive staff provide restaurant recommendations and arrange transportation.

Popular amenities

  • Pet friendly
  • Free WiFi
  • Laundry
  • Housekeeping
The current price is NT$5,227
NT$6,113 total
includes taxes & fees
Nov 17 - Nov 18

Room options

Available filters for rooms
Showing 4 of 4 rooms

View all photos for Superior Room, 1 Queen Bed, Courtyard View

A hotel room with a bed, a desk, a chair, a TV, and a window with a view.

Superior Room, 1 Queen Bed, Courtyard View

10.0 out of 10
Exceptional
(2 reviews)
  • 215 sq ft
  • 1 bedroom
  • Sleeps 3
  • 1 Queen Bed
  • Free wired internet

View all photos for Deluxe Room, City View

A hotel room with a large bed, a window with a view of buildings, a small table with a lamp, and a chair.

Deluxe Room, City View

9.8 out of 10
Exceptional
(6 reviews)
  • City view
  • 258 sq ft
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed OR 2 Twin Beds
  • Free wired internet

View all photos for Junior Suite

A hotel room with a bed, a desk, a chair, a TV, and a window with a view of a building.

Junior Suite

10.0 out of 10
Exceptional
(3 reviews)
  • City view
  • 431 sq ft
  • 1 bedroom
  • Sleeps 4
  • 1 King Bed
  • Free wired internet

View all photos for Grand Room

A modern bedroom with a large bed, bedside tables, a mirror, and decorative plants.

Grand Room

  • City view
  • 366 sq ft
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed
  • Free wired internet

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About the neighborhood

Located in Rome City Centre neighborhood, Domus 21 Luxury Suites is connected to a rail/subway station. Vatican Museums and Castel Sant'Angelo are cultural highlights, and travelers looking to shop may want to visit Via del Corso and Via Veneto. Looking to enjoy an event or a game? See what's going on at Foro Italico or Stadio Olimpico. Be sure not to miss outdoor adventures like ziplining, skydiving, and ecotours, or hop on a segway rental nearby and take a self-guided tour around the aera. Visit our Rome travel guide
View more Guest Houses in Rome
Map
Corso Vittorio Emanuele II 21, Rome, RM, 00186

What's nearby

  • Ancient ruins with columns and buildings in the background.
    Largo di Torre Argentina
    2 min walk - 0.2 km
  • Teatro Faiano
    1 min walk - 0.0 km
  • Piazza della Minerva
    2 min walk - 0.2 km
  • Chiesa del Gesù
    2 min walk - 0.2 km
  • Crypta Balbi
    2 min walk - 0.2 km

Getting around

  • Venezia Tram Stop
    4 min walk
  • Rome San Pietro Station
    5 min drive
  • Fiumicino - Leonardo da Vinci Intl. Airport (FCO)
    40 min drive

Restaurants

  • Shari Vari
    5 min walk
  • Cafffè Camerino
    5 min walk
  • PASTAEAT la pastapoke
    1 min walk
  • Te Amo
    5 min walk
  • Trentaquattro Roma - Largo Argentina
    2 min walk

About this property

Domus 21 Luxury Suites

  • Luxury family-friendly guesthouse connected to the convention center
  • A short walk from Pantheon and Campo de' Fiori, Domus 21 Luxury Suites provides dry cleaning/laundry services and more. Guests can connect to free in-room WiFi.
  • Other perks include:
    • A roundtrip airport shuttle (surcharge), an electric car charging station, and express check-out
    • Express check-in, concierge services, and bicycle parking
    • Smoke-free premises, helicopter/airplane tours, and books
    • Guest reviews speak highly of the helpful staff
  • Room features
  • All guestrooms at Domus 21 Luxury Suites have comforts such as premium bedding and pillow menus, in addition to thoughtful touches like laptop-compatible safes and air conditioning.
  • Extra amenities include:
    • Highchairs, children's books, and art supplies
    • Reusable coffee/tea filters, recycling, and composting
    • Rainfall showers, designer toiletries, and bidets
    • Childcare services, free infant beds, and electric kettles

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Frequently asked questions

Is Domus 21 Luxury Suites pet-friendly?

Yes, this property allows cats and dogs (limit 4 total) with a maximum weight of up to 22 lbs per pet.

How much does it cost to stay at Domus 21 Luxury Suites?

As of 2026/11/13, prices found for a 1-night stay for 2 adults at Domus 21 Luxury Suites on 2026/11/17 start from NT$5,227, excluding taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

What time is check-in at Domus 21 Luxury Suites?

Check-in start time: 2:00 PM; Check-in end time: 11:00 AM.

What time is check-out at Domus 21 Luxury Suites?

Check-out is at 11:00 AM.

Does Domus 21 Luxury Suites provide a shuttle to the airport?

Yes, there's an airport shuttle that runs on request. A fee of EUR 80 per vehicle applies.

Where is Domus 21 Luxury Suites located?

This family-friendly Rome guesthouse is located near the airport, within a 5-minute walk of Corso Vittorio Emanuele II, Pantheon, and Piazza Venezia. Piazza Navona and Campo de' Fiori are also within 10 minutes. Venezia Tram Stop and Arenula-Cairoli Tram Station are within a 5-minute walk.

Can I cancel my reservation for free and receive a full refund?

Yes, this property offers free cancellation on select room rates, because flexibility matters! Please refer to the property cancellation policy on our site for more details about any exclusions or requirements.

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Reviews

Domus 21 Luxury Suites Reviews

9.6

Exceptional

9.8

Cleanliness

9.4

Amenities

9.8

Staff & service

9.6

Property conditions & facilities
Rating 10 - Excellent. 100 out of 119 reviews
Rating 8 - Good. 15 out of 119 reviews
Rating 6 - Okay. 3 out of 119 reviews
Rating 4 - Poor. 0 out of 119 reviews
Rating 2 - Terrible. 1 out of 119 reviews

Reviews

Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great spot. Perfect location.
Stayed 2 nights in Sep 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Our stay at the Domus 21 was great. The staff is excellent. The rooms are beautiful and clean. And the shower is the best anywhere. Thank you
Stayed 3 nights in Sep 2026
Verified review

8/10 Good

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Perfect location, helpful and friendly staff who were brilliant, they contacted us with all the check-in information, offered to arrange our airport transfer. The rooms were clean and comfortable. Would definitely stay there again
Stayed 4 nights in Jun 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Would definitely stay here again - staff were very friendly and helpful and was a lovely room in a very convenient location for sightseeing
Stayed 2 nights in May 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Only 7 suites, owner greeted us and our rooms were available upon arrival at 11:30 am. Great restaurants & shopping close. Super experience and will stay here again!
Stayed 2 nights in Jun 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Perfect spot for a quick Rome trip. The room was beautiful with high ceilings, the staff were very friendly and helpful with luggage staying after check-out and the location is right in the middle of everything. Perfect!
Stayed 1 night in Jul 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Lovely room and host, fantastic location
Stayed 1 night in Mar 2026
Verified review

6/10 Okay

Liked: Cleanliness, staff & service, property conditions & facilities
First of all the entrance is daunting. Everything is by keypad. As a 71 year old once we entered through the old door from the street using the key pad we found ourselves having to carry the luggage up a extra long flight of stairs to get to the rickety old elevator to take us to the fifth floor. Had I known this was a requirement I would not have booked it. This is Definitely accommodation for a much younger traveller. As for the room it was nice, location is great and is well kept. I would recommend the place and increase my stars to 4 but only for the 50 or younger. For the older traveller it can be considered but you need to be somewhat in shape.
Stayed 2 nights in Oct 2026
Verified review

10/10 Excellent

Liked: Staff & service, amenities, property conditions & facilities
Room was in a great location! Walking distance from Trevi fountain. Elevator made it easy to go to the 5th floor. Room was huge with high ceilings and a great shower. Will stay again when visiting Rome.
Stayed 2 nights in Jun 2026
Verified review

10/10 Excellent

Perfect location to see all of Rome on foot. Beautiful room. Wonderful helpful staff.
Stayed 3 nights in Mar 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Domus 21 was a great combination of modern amenities with old world feel. The historic feel of the property from the street to the entry way is carried over into the room with an excellent fresco on the ceiling along with Roman inspired decorations. While modern feeling with concrete and clean lines, it still feels respectful to the past: the shower feel akin to your own personal Roman bath and the view out the window transports you to another time entirely. I would definitely return to this property the next time my travels bring me to Rome.
Stayed 2 nights in May 2026
Verified review

6/10 Okay

First I will say housekeeping was outstanding.
Stayed 4 nights in Feb 2026
Verified review

8/10 Good

Liked: Cleanliness, staff & service, amenities
Was shown the room and amenities. Great location
Stayed 1 night in Nov 2025
Verified review

10/10 Excellent

Liked: Cleanliness, amenities, property conditions & facilities
Very lovely property! Close to so many restaurants, shopping, bus stops and site seeing.
Stayed 4 nights in Jun 2025
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Very good location and stylish
Stayed 2 nights in Nov 2024
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Lovely size rooms that are really clean and quiet. Great location and friendly reception staff
Stayed 4 nights in Oct 2024
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Nice staff. Great location
Stayed 1 night in Apr 2025
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Excellent location and service. Even though the hotel doesn't have a 24 hr reception, the staff is invaluable with anything, and the size of the room and location are superb.
Stayed 5 nights in Apr 2025
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Perfect Stay in Rome

Great location. Super clean. Friendly staff. Comfy bed. Hot shower. Everything I needed for my stay in Rome.
Stayed 1 night in Aug 2025
Verified review

8/10 Good

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Location, location, location. Great restaurants all around. Walkable to Trevi, the Colosseum and Pantheon.
Stayed 3 nights in Mar 2025
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Love this hotel!!! Awesome location, very nice inside, beds are super comfortable and staff was friendly and helpful! It also has a lift, which is great when u don’t pack light:-) They do not 24 reception so if you are arriving early or late you will just need to make arrangements.
Stayed 1 night in Oct 2025
Verified review

8/10 Good

Liked: Cleanliness, staff & service, property conditions & facilities
Fabulous location. Very quiet and peaceful room.
Stayed 4 nights in Sep 2023
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
This is exceptional space to spend time in Rome. The staff and rooms are superior. Their space is very aesthetic and the attention to detail in their design did not go unnoticed. I would not hesitate to stay here again! Thank you for the beautiful accommodations!
Stayed 1 night in Jun 2025
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Very nice rooms. good location. walkable to colusseum and many nice areas.
Stayed 3 nights in Mar 2024
Verified review

8/10 Good

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The property is in an excellent location. Walkable to many dining options and close to a lot of sight seeing. The suites are a little hard to find once you arrive and you have to go up the oldest and smallest elevator which was an Experience in itself! more directions prior Would have been helpful but overall it’s a great place for a quick trip in Rome!
Stayed 2 nights in Jun 2025