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In the heart of Rome, Domus 21 Luxury Suites is a haven for families. Unwind with pet-sitting services and explore coworking spaces while staying connected with in-room WiFi. Express check-in and out ensure a seamless stay, leaving previous guests to rave about the helpful staff.
VIP Access
Reviews
9.8 out of 10
Exceptional
Popular amenities
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Room options
Available filters for rooms
Showing 4 of 4 rooms
View all photos for Grand Room

Grand Room
Highlights
Soundproofed
Air conditioning
Connecting rooms available
Free cribs/infant beds
Minibar (some free items)
Smart TV
Hypo-allergenic bedding
Pillow menu
View all photos for Junior Suite

Junior Suite
10.0 out of 10
Exceptional
(3 reviews)
Highlights
Soundproofed
Air conditioning
Connecting rooms available
Free cribs/infant beds
Minibar (some free items)
Smart TV
Hypo-allergenic bedding
Pillow menu
View all photos for Superior Room, 1 Queen Bed, Courtyard View

Superior Room, 1 Queen Bed, Courtyard View
10.0 out of 10
Exceptional
(1 review)
Highlights
Separate sitting area
Soundproofed
Individually furnished
Individually decorated
Air conditioning
Connecting rooms available
Free cribs/infant beds
Minibar (some free items)
View all photos for Deluxe Room, City View

Deluxe Room, City View
9.6 out of 10
Exceptional
(4 reviews)
Highlights
Soundproofed
Air conditioning
Connecting rooms available
Free cribs/infant beds
Minibar (some free items)
Smart TV
Hypo-allergenic bedding
Pillow menu
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About the neighborhood
Located in Rome City Centre neighborhood, Domus 21 Luxury Suites is connected to a rail/subway station. Vatican Museums and Castel Sant'Angelo are cultural highlights, and travelers looking to shop may want to visit Via del Corso and Via Veneto. Looking to enjoy an event or a game? See what's going on at Foro Italico or Stadio Olimpico. Be sure not to miss outdoor adventures like mountain climbing, skydiving, and ziplining, or hop on a segway rental nearby and take a self-guided tour around Rome.

Corso Vittorio Emanuele II 21, Rome, RM, 00186
What's nearby
- Pantheon - 3 min walk - 0.3 km
- Piazza Navona - 6 min walk - 0.6 km
- Trevi Fountain - 8 min walk - 0.7 km
- Spanish Steps - 15 min walk - 1.3 km
- Colosseum - 19 min walk - 1.7 km
Getting around
Restaurants
- Scholars Lounge - 2 min walk
- Vini & Cucina Blasi - 4 min walk
- PASTAEAT la pastapoke - 1 min walk
- Pizza e Mozzarella - 3 min walk
- Bar Amore - 4 min walk
About this property
Property amenities
Room amenities
Policies
Important information
Fees
You'll be asked to pay the following charges at the property. Fees may include applicable taxes:
- A tax is imposed by the city: EUR 5.00 per person, per night, up to 10 nights. This tax does not apply to children under 10 years of age.
We have included all charges provided to us by the property.
Optional extras
- Airport shuttle fee: EUR 70 per vehicle (one-way, maximum occupancy 2)
- Airport shuttle fee per child: EUR 70 (one-way), (from 10 to 18 years old)
- Nearby parking fee: EUR 24 per day (3281 ft away)
The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.
You need to know
Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards, debit cards, and cash
Cashless transactions are available
Safety features at this property include a fire extinguisher, a security system, a first aid kit, and window guards
Property Registration Number IT058091B4OUIRD7WF
We should mention
All guests, including children, must be present at check-in and show their government-issued photo ID card or passport
Cash transactions at this property cannot exceed EUR 5000, due to national regulations; for further details, please contact the property using information in the booking confirmation
The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation
Property is also known as
Domus 21 Luxury Suites Rome
Domus 21 Luxury Suites Guesthouse
Domus 21 Luxury Suites Guesthouse Rome
Frequently asked questions
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Domus 21 Luxury Suites Reviews
Reviews
9.8
Exceptional
10/10
Cleanliness
9.8/10
Staff & service
9.4/10
Amenities
9.6/10
Property conditions & facilities
9.8/10
Eco-friendliness
Reviews
2025/7/16
Liked: Cleanliness, amenities, property conditions & facilities
Stayed 4 nights in Jun 2025
10/10 Excellent
Nhu
2025/6/24
Liked: Cleanliness, staff & service, amenities, property conditions & facilities


Nhu
Stayed 1 night in Jun 2025
8/10 Good
Caitlyn
2025/7/6
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Caitlyn
Stayed 2 nights in Jun 2025
10/10 Excellent
Jeffrey
2025/4/20
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Jeffrey
Stayed 1 night in Apr 2025
10/10 Excellent
Jose
2025/4/27
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Jose
Stayed 5 nights in Apr 2025
8/10 Good
Dennis
2025/3/25
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Dennis
Stayed 3 nights in Mar 2025
10/10 Excellent
Yuri
2024/11/20
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Yuri
Stayed 2 nights in Nov 2024
10/10 Excellent
Mikeala
2024/10/27
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Mikeala
Stayed 4 nights in Oct 2024
10/10 Excellent
Gregory
2025/4/26
Liked: Cleanliness, staff & service, property conditions & facilities
Gregory
Stayed 3 nights in Apr 2025
8/10 Good
Julie
2024/7/2
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Julie
Stayed 1 night in Jun 2024
10/10 Excellent
Robert Anthony
2023/4/8
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Robert Anthony
Stayed 6 nights in Apr 2023
10/10 Excellent
Sandra
2025/4/23
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Sandra
Stayed 1 night in Apr 2025
10/10 Excellent
Eusebio Dan
2023/5/26
Liked: Cleanliness, staff & service, property conditions & facilities
Eusebio Dan
Stayed 3 nights in May 2023
10/10 Excellent
Cynthia
2023/6/18
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Great location!
Cynthia
Stayed 2 nights in Jun 2023
10/10 Excellent
Mert
2022/7/20
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Mert
Stayed 1 night in Jul 2022
10/10 Excellent
Leslie
2022/7/12
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Leslie
Stayed 4 nights in Jul 2022
10/10 Excellent
zeline
2024/3/11
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
zeline
Stayed 3 nights in Mar 2024
10/10 Excellent
Diana
2024/8/3
Liked: Cleanliness, staff & service, property conditions & facilities
Diana
Stayed 5 nights in Jul 2024
10/10 Excellent
Angela
2024/7/28
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Angela
Stayed 2 nights in Jul 2024
10/10 Excellent
Wei
2022/9/5
Liked: Staff & service, amenities, property conditions & facilities
Wei
Stayed 9 nights in Aug 2022
10/10 Excellent
Verified traveler
2024/7/17
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Great room, fantastic service
Verified traveler
Stayed 1 night in Jul 2024
10/10 Excellent
Jose
2022/12/10
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Jose
Stayed 2 nights in Dec 2022
6/10 Okay
Peter
2025/3/2
Liked: Cleanliness, staff & service
Disliked: Amenities, property conditions & facilities
Peter
Stayed 2 nights in Feb 2025
10/10 Excellent
Amelia
2022/12/15
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Amelia
10/10 Excellent
Anthony
2024/2/24
Liked: Cleanliness, staff & service, amenities, property conditions & facilities