A wooden bridge over water, surrounded by palm trees and outdoor seating areas.

Find Resorts & Hotels with Spas in Plantation Key, FL

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Plantation Key Resorts & Hotels with Spas

Tonight
Aug 24 - Aug 25
Tomorrow
Aug 25 - Aug 26
This weekend
Aug 28 - Aug 30
Next weekend
Sep 4 - Sep 6

Our top choices for Plantation Key hotels with a spa

A view through a window with metal bars, featuring a beach with palm trees, a thatched umbrella, and a wooden dock.
A beachside resort with lounge chairs, a pool, and palm trees.
A clear blue pool surrounded by palm trees and a thatched-roof structure, with a sign indicating no diving.
A beach with kayaks lined up near the water's edge, palm trees, and lounge chairs.

1. Kona Kai Resort and Gallery - Adults Only

Kona Kai Resort and Gallery - Adults Only
Rock Harbor
  • Serene spa getaway with tranquil gardens and sunset views from the oceanfront hot tub.
NT$2,358
NT$3,549 total
includes taxes & fees
Sep 9 - Sep 10
Kona Kai Resort and Gallery - Adults Only
A conference room with a large painting of a blue ocean, two Laptops, and wicker chairs.
A balcony with a view of palm trees and the sea, a white railing, and a table with chairs.
A bar area with a thatched roof, wooden chairs, and a view of the ocean.
A bathroom with a large bathtub, a window with curtains, and a view of palm trees and the sea.

2. Cheeca Lodge & Spa

Cheeca Lodge & Spa
Matecumbe
  • Luxury spa sanctuary with 7 treatment rooms offers beachside massages and tranquil gardens for ultimate rejuvenation.
NT$4,747
NT$7,670 total
includes taxes & fees
Aug 27 - Aug 28
Cheeca Lodge & Spa
A spacious lobby with hanging chairs, a round wooden table with a starfish and a cactus, and a reception desk in the background.
A beach with clear water, a wooden pier, and lounge chairs under a tree.
A beachside patio with lounge chairs, a table, and a view of the ocean.
An aerial view of a resort with a large pool, palm trees, and a beach.

3. Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection
Rock Harbor
  • Immerse in waterfront wellness at this bay resort with a full-service spa, offering daily Ayurvedic treatments and relaxing garden escapes.
NT$7,869
NT$10,609 total
includes taxes & fees
Sep 20 - Sep 21
Playa Largo Resort & Spa, Autograph Collection
A hotel room with two beds, a large window with a view of a balcony, and a curtain on the window.
A balcony with two wooden chairs and a small table, overlooking a beach with palm trees and the ocean.
A modern hotel room with a balcony, a flat-screen TV, a sofa, a dining table, and a view of the ocean.
A balcony with a wooden table, two chairs, and a view of the ocean and palm trees.

4. The Islands of Islamorada

The Islands of Islamorada
Matecumbe
  • Beachfront spa villa with two pools, massage services, and scenic water walkway offers rejuvenating Florida escape.
NT$11,469
NT$14,889 total
includes taxes & fees
Aug 25 - Aug 26
The Islands of Islamorada
A hotel room with a bed, a dresser, a mirror, and a nightstand.
A beach with thatched umbrellas, palm trees, and blue lounge chairs.
A spacious bar area with high ceilings and large windows, offering views of the ocean.
A poolside area with blue chairs and a thatched-roof structure.

5. Reefhouse Resort & Marina

Reefhouse Resort & Marina
Key Largo
  • Discover tranquil bliss at this waterfront haven with three spa rooms, private beach, and hot stone massages.
NT$6,977
NT$9,124 total
includes taxes & fees
Aug 25 - Aug 26
Reefhouse Resort & Marina
A wooden table with two white cups, one with coffee and one with tea, placed on a body of water.
A couple in a room with a large window overlooking the sea, a bed with pillows, a small table with a vase of flowers, and a plant.
A room with a bed, two chairs, and a view of a lake.
A floating house with a thatched roof, large sliding glass doors, and a wooden deck with a chair.

6. Premium Floating Bungalow by Stay Ombi

Premium Floating Bungalow by Stay Ombi
Key Largo
  • Luxurious massages offered on spa-equipped houseboat with premium floating rooms and serene water access.
NT$26,214
NT$29,491 total
includes taxes & fees
Aug 25 - Aug 26
Premium Floating Bungalow by Stay Ombi
View all properties

Choose what matters most at spa hotels in Plantation Key

Pool
Breakfast included
Hot tub
4 stars
5 stars

Top Plantation Key Hotel Reviews

Lime Tree Bay Resort

Lime Tree Bay Resort

10/10 Excellent
"We came for a quick weekend trip but wish we could have stayed longer! I have been here before and enjoyed my stay then and now. I like the location, space and amenities. I will be back!"
stefanie 2-night trip
Posted 2 hours ago
Lime Tree Bay Resort
Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton

10/10 Excellent
"Espectacular"
Angélica Maria 1-night trip
Posted 4 hours ago
Baker's Cay Resort Key Largo, Curio Collection by Hilton
Islander Resort

Islander Resort

10/10 Excellent
"We had a wonderful stay at the Islander Resort in Islamorada! The property is beautiful, relaxing, and has that perfect Florida Keys atmosphere. The grounds are very well maintained, the pools are great, and the oceanfront setting makes it easy to relax and enjoy the gorgeous views. Our room was comfortable and clean, and we really enjoyed the resort amenities. The food and drinks were excellent, and it was so convenient to have everything we needed right on the property. The staff was friendly and welcoming throughout our stay. The location is also fantastic—close to some of our favorite restaurants and everything Islamorada has to offer, while still feeling peaceful and tropical once you’re at the resort. Highly recommend Squares Grouper for dinner, Green Turtle Inn for breakfast. We had such an enjoyable and relaxing getaway and would definitely stay at the Islander Resort again. Highly recommend it for anyone looking for a beautiful Keys vacation!"
Rosa 2-night trip
Posted 7 hours ago
Islander Resort
Chesapeake Beach Resort

Chesapeake Beach Resort

10/10 Excellent
"The staff was excellent and the amenities were very convenient"
Jamie 2-night trip
Posted 9 hours ago
Chesapeake Beach Resort
Cheeca Lodge & Spa

Cheeca Lodge & Spa

10/10 Excellent
"The the property and location . Close to all the good restaurants. Food was delicious and room was clean and comfortable."
Krystyna 3-night trip
Posted 12 hours ago
Cheeca Lodge & Spa
Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection

10/10 Excellent
"Excellent room clean and staff was wonderful pool was perfect and water temp was cool for how warm it is"
Robert 2-night trip
Posted 1 day ago
Playa Largo Resort & Spa, Autograph Collection
Holiday Inn Key Largo by IHG

Holiday Inn Key Largo by IHG

10/10 Excellent
"Excellent property all the way around. Will be returning next year for sure!!"
Michael 5-night trip
Posted 2 days ago
Holiday Inn Key Largo by IHG

Explore a world of travel with Expedia