A grand historic building with a dome and classical architecture, surrounded by lush greenery and a well-maintained garden.

Find Resorts & Hotels with Spas in Odessa, FL

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Check availability on Odessa Resorts & Hotels with Spas

Tonight
Aug 31 - Sep 1
Tomorrow
Sep 1 - Sep 2
This weekend
Sep 4 - Sep 6
Next weekend
Sep 11 - Sep 13

Our top choices for Odessa hotels with a spa

An open doorway leading to a reception area with a dark wood reception desk, a chandelier, and decorative wall sconces.
A spacious bar area with high ceilings and stone pillars, surrounded by multiple seating options including bar stools and cushioned chairs.
A golf course with a pond, trees, and a clear sky.
A bar area with a long counter, multiple bar stools, and a well-stocked liquor shelf.

1. Innisbrook Resort

Innisbrook Resort
Palm Harbor
  • Escape to a resort sanctuary with 12 treatment rooms, tranquil gardens, and 6 outdoor pools where spa indulgence meets golf getaways.
NT$3,913
NT$6,029 total
includes taxes & fees
Sep 1 - Sep 2
Innisbrook Resort
A multi-story hotel with a covered entrance, outdoor seating area, and a staircase leading to the upper levels.
A modern bathroom with a large mirror, a sink, a toilet, and a shower.
A hotel lobby with a reception desk, a clock, a sofa, and a large window.
A covered outdoor area with two Adirondack chairs, a wooden ceiling, and a view of a residential neighborhood with houses and trees.

2. The Grant Street Inn Dunedin Downtown Historic District, an Ascend Collection Hotel

The Grant Street Inn Dunedin Downtown Historic District, an Ascend Collection Hotel
Downtown Dunedin
  • Immerse in coastal wellness at this spa hotel with outdoor pool and balconies overlooking downtown Dunedin.
NT$3,912
NT$4,420 total
includes taxes & fees
Sep 1 - Sep 2
The Grant Street Inn Dunedin Downtown Historic District, an Ascend Collection Hotel
A poolside area with lounge chairs, a person sitting on the edge of the pool, and a building in the background.
A patio with two chairs and a table, overlooking a pond with lily pads and a grassy area with trees.
An aerial view of a golf course with a pond, surrounded by buildings with blue roofs, and dense greenery.

3. Saddlebrook Resort

Saddlebrook Resort
Wesley Chapel South
  • Rejuvenate your spirit at this premier golf resort with 12 treatment rooms and soothing sauna facilities for total wellness.
NT$4,093
NT$5,576 total
includes taxes & fees
Sep 20 - Sep 21
Saddlebrook Resort
A lobby with a reception desk, seating area, and artwork.
A poolside bar area with a neon sign reading "PARTHENON Bar" and several people seated at tables.
A bar area with a counter, seating, and a television screen.
A circular fountain with tiered water features, surrounded by a tiled border and decorated with white and red flowers.

4. Safety Harbor Resort & Spa Trademark Collection by Wyndham

Safety Harbor Resort & Spa Trademark Collection by Wyndham
Safety Harbor
  • Luxuriate in a waterfront wellness haven with 15 treatment rooms, hot mineral springs, and serene pools for a rejuvenating spa retreat.
NT$6,155
NT$7,903 total
includes taxes & fees
Sep 7 - Sep 8
Safety Harbor Resort & Spa Trademark Collection by Wyndham
A Sleep Inn & Suites hotel with a modern design, featuring a central entrance and multiple floors.
A hotel room with a dark wood desk, a flat-screen TV mounted on the wall, a comfortable office chair, and a minibar with various items.
A hotel room with a bed, bedside tables, a nightstand, a mirror, and a green wall.
A modern hotel lobby with a bar area, seating arrangements, and a large screen.

5. Sleep Inn & Suites Tampa South

Sleep Inn & Suites Tampa South
Sun Bay South
  • Pamper yourself at this Tampa hotel with a full-service spa, outdoor pool, and hot tub, all conveniently located near Tampa Riverwalk.
NT$3,291
NT$3,735 total
includes taxes & fees
Oct 1 - Oct 2
Sleep Inn & Suites Tampa South
A hotel room with two beds, a large window with a city view, a sink, and a mirror.
A hotel with a central courtyard, multiple floors, and a view of the sunset over the water.
A coastal cityscape at sunset with a beach in the foreground and high-rise buildings in the background.
A balcony with a table and chairs, overlooking a beach with blue umbrellas and a clear view of the ocean.

6. Hyatt Regency Clearwater Beach Resort and Suites

Hyatt Regency Clearwater Beach Resort and Suites
Clearwater Beach
  • Seaside spa sanctuary offers couples' massages and hot stone treatments in 8 serene rooms.
NT$6,020
NT$8,053 total
includes taxes & fees
Sep 1 - Sep 2
Hyatt Regency Clearwater Beach Resort and Suites
A modern spa and salon interior with a central reception desk, seating area, and large windows.
A modern bar area with a high ceiling, bar stools, and a counter with a marble top.
A hotel with multiple floors, a swimming pool area, and a dome structure.
A pool bar and grill with outdoor seating and a modern architectural design.

7. Seminole Hard Rock Hotel & Casino Tampa

Seminole Hard Rock Hotel & Casino Tampa
Tampa
  • Luxurious spa retreat with 13 treatment rooms and three outdoor pools offers ultimate relaxation getaway.
NT$7,086
NT$8,940 total
includes taxes & fees
Sep 1 - Sep 2
Seminole Hard Rock Hotel & Casino Tampa
A bedroom with a bed, a ceiling fan, a flat-screen TV, a dresser, a mirror, and a walk-in closet.
A bathroom with a shower, toilet, sink, and a mirror.
A spacious living room with a white sofa, a glass coffee table, and a ceiling fan. A dining area is visible in the background with a chandelier.
A modern kitchen with stainless steel appliances, white cabinetry, and a granite countertop.

8. Sleeps 6 Hot Tub Fenced Yard Cozy Chic

Sleeps 6 Hot Tub Fenced Yard Cozy Chic
Town 'n' Country
  • Unwind in a tranquil villa with a daily full-service spa and hot tub surrounded by a private fenced yard.
NT$5,748
NT$11,267 total
includes taxes & fees
Sep 1 - Sep 2
Sleeps 6 Hot Tub Fenced Yard Cozy Chic
A reception area with a glass door, a sign reading "Hibiscus SPA", and a wooden floor.
A resort with a swimming pool, beach, and a pier.
A balcony with two wicker chairs and a small round table, overlooking a beach with umbrellas and people.
A beach resort with a large pool area, multiple hotel buildings, and a sandy beach with umbrellas.

9. Hilton Clearwater Beach Resort & Spa

Hilton Clearwater Beach Resort & Spa
Clearwater Beach
  • Indulge in restorative treatments at this waterfront sanctuary with 7 spa rooms and beachfront yoga sessions.
NT$5,160
NT$7,081 total
includes taxes & fees
Sep 7 - Sep 8
Hilton Clearwater Beach Resort & Spa
A person receiving a manicure in a room with a sofa, a small table with a bottle, and wooden crates labeled 'Carmats' and 'Pall Hores'.
An outdoor seating area with tables and chairs, a brick wall, and a sign for the Epicurean Theatre.
A modern interior with a wooden ceiling, two seating areas with tables, a bicycle, and a large window.
A modern interior with leather sofas, a wooden wall, and a bar area.

10. Epicurean Hotel, Autograph Collection

Epicurean Hotel, Autograph Collection
Hyde Park
  • Discover the ultimate pampering oasis at this hotel with a full-service spa, rooftop garden, and outdoor pool for a rejuvenating escape.
NT$6,292
NT$7,194 total
includes taxes & fees
Sep 21 - Sep 22
Epicurean Hotel, Autograph Collection
View all properties

Choose what matters most at spa hotels in Odessa

Pool
Breakfast included
Hot tub
4 stars
5 stars

Top Odessa Hotel Reviews

Sandpearl Resort

Sandpearl Resort

10/10 Excellent
"Habitaciobes limpias, personal amable, la playa espectacular la sillas y la sombrillas hay q pagar por usarlas"
Nilda 2-night trip
Posted 10 hours ago
Sandpearl Resort
Hyatt Regency Clearwater Beach Resort and Suites

Hyatt Regency Clearwater Beach Resort and Suites

10/10 Excellent
"This is a great place to stay! I recently had a work trip and chose"
Alicia 2-night trip
Posted 13 hours ago
Hyatt Regency Clearwater Beach Resort and Suites
Wyndham Grand Clearwater Beach

Wyndham Grand Clearwater Beach

10/10 Excellent
"First time visiting the resort and Clearwater. Great service, cleanliness and amenities. Will definitely be back!"
Nikki 2-night trip
Posted 14 hours ago
Wyndham Grand Clearwater Beach
The Westin Tampa Bay

The Westin Tampa Bay

10/10 Excellent
"This was an excellent choice"
LUCY 1-night trip
Posted 14 hours ago
The Westin Tampa Bay
Clearwater Beach Sheraton Resort on Sand Key

Clearwater Beach Sheraton Resort on Sand Key

10/10 Excellent
"Rooms clean and tidy. Front desk was able to get adjoining rooms w friends that made the weekend much more enjoyable. Trolley was a great way to travel"
Kathryn 2-night trip
Posted 17 hours ago
Clearwater Beach Sheraton Resort on Sand Key

Frequently asked questions

Looking to vacation at a spa hotel in Odessa?
Soothe the senses with some time in one of our wonderful spa hotels. Check out the lakeside setting in Odessa - worth a picture or two! Take part in recreational activities such as golfing during your vacation. Spa hotels are a great way to break away from your routine and add a layer of luxury to your weekend away.
What's there to see and do in Odessa?
Enjoy Odessa with a stop at Crescent Lake, Silver Dollar Golf Club, and The Eagles Golf Club. If you have extra time while you're in the area, you might want to see Old McMicky's Farm and Brooker Creek Headwaters Nature Preserve.
What is a Odessa spa hotel?
Spa hotels in Odessa have full on-site spas and offer services like therapies and a range of beauty treatments. Some also provide a selection of in-room treatments for the ultimate luxury. Spa hotels are a must if you want to give yourself an extra treat while on vacation.

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