Northeast Missouri, MO
Travel Guide
Visit Northeast Missouri
Where to stay in Northeast Missouri
Clayton
Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.
Central West End
Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.
Soulard
You'll enjoy the bars and churches in Soulard. You might want to make time for a stop at Anheuser-Busch Brewery or Soulard Farmer's Market.
Downtown West
If you're spending some time in Downtown West, St. Louis Union Station and St. Louis Aquarium at Union Station are top sights worth seeing.
Creve Coeur
Creve Coeur is known for its abundant dining options, and you can plan a trip to Creve Coeur Golf Club and Saint Louis Abbey while you're in town.
Berkeley
Visitors highly recommend Berkeley for its abundant dining options, and you can make a stop by James S. McDonnell Prologue Room while you're in town.
Clayton Plaza Hotel & Extended Stay
Lovely hotel. Great breakfast
Reviewed on 2026/1/29
21C Museum Hotel St Louis
Very nice and clean
Reviewed on 2026/1/29
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Everything was great, except the rooms are without microwave. I went to the 8th floor and a homeless man was using the microwave. Not safe to go alone. The issue is not he was homeless, it was that security was not with him
Reviewed on 2026/1/30
White House at Grand Central
Great place
Reviewed on 2025/12/27
Lighthouse Inn & Suites
Nice room. Matched the pictures. Exactly what we were looking for.
Reviewed on 2026/1/18
Check Northeast Missouri hotel availability
Popular places to visit
St. Louis Union Station
You can learn about the local history of St. Louis when you make a stop at a well-known site like St. Louis Union Station. Experience the area's acclaimed art scene or attend a baseball game.
Busch Stadium
Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's great live music or attend a baseball game.
St. Louis Zoo
In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world.
Enterprise Center
Catch an event at Enterprise Center during your trip to St. Louis. Experience the area's acclaimed theater scene or attend a baseball game.
Washington University in St. Louis
Enjoy the collegiate vibe at Washington University in St. Louis during your stay in St. Louis. Amble around the area's lush forest or attend a sporting event.
Dome at America’s Center
Catch an event at Dome at America’s Center during your trip to St. Louis. Experience the area's acclaimed theater scene and great live music.
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- Visit Hannibal
- Truman State University
- Visit Callao
- Visit Curryville
- Visit Stoutsville
- Magic City Line Mini Train
- Jim's Journey: The Huck Finn Freedom Center
- Visit Higbee
- Kahoka Vacations
- Visit Lentner
- Memphis Vacations
- Mark Twain Memorial Lighthouse
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- Visit Shelbina
- Visit Mexico
- Visit La Plata
- Visit Renick
- Visit Holliday
- Visit New London
- Visit La Grange
- Visit Gibbs
- Visit Rucker
- Visit Novinger
- Mark Twain Casino
- Car rental Kahoka
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- Car rental Monroe City
- Dollar Rent A Car Rental Cars in Granger
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- First-Car Rental Cars in Taylor
- Budget Rental Cars in Holliday
- Top Rent a Car Rental Cars in Edina
- Car rental Hannibal
- Rental cars Kirksville Municipal airport
- St. Louis Zoo
- Enterprise Center
- America's Center Convention Complex
- Dome at America’s Center
- Barnes Jewish Hospital
- City Museum
- Forest Park
- Six Flags St. Louis
- Ameristar Casino St. Charles
- Mississippi River
- Meramec Caverns
- Anheuser-Busch Brewery
- Chaifetz Arena
- Purina Farms
- Magic House - St. Louis Children's Museum
- Hidden Valley Ski Resort
- Missouri Botanical Gardens and Arboretum
- Grant's Farm
- St. Louis Science Center
- Stone Hill Winery
