Find hotels in Northeast Missouri, MO from NT$2,273
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Go beyond your typical stay in Northeast Missouri
Pet friendly
Family friendly
Cottage
Waterpark
Condo
Apartment
Check prices for these dates
Tonight
Aug 30 - Aug 31Tomorrow
Aug 31 - Sep 1Next weekend
Sep 4 - Sep 6In two weeks
Sep 11 - Sep 13Our top choices for Northeast Missouri hotels
1. Depot Inn and Suites
Depot Inn and SuitesLa Plata
David
NT$3,036
NT$3,290 total
includes taxes & fees
Sep 28 - Sep 29
2. Oak Hill Inn & Suites
Oak Hill Inn & SuitesCanton
Marie
NT$3,201
NT$3,648 total
includes taxes & fees
Aug 31 - Sep 1
3. Hampton Inn Kirksville
Hampton Inn KirksvilleKirksville
Linda
NT$3,604
NT$4,084 total
includes taxes & fees
Sep 6 - Sep 7
4. Sleep Inn & Suites Hannibal West
Sleep Inn & Suites Hannibal WestHannibal
Steve
NT$3,736
NT$4,347 total
includes taxes & fees
Sep 20 - Sep 21
5. Wingate by Wyndham St. Louis Airport
Wingate by Wyndham St. Louis AirportSt. Ann
Margaret
NT$3,494
NT$4,114 total
includes taxes & fees
Sep 6 - Sep 7
6. Quality Inn & Suites Hannibal West
Quality Inn & Suites Hannibal WestHannibal
Mohamed
NT$2,591
NT$3,014 total
includes taxes & fees
Sep 20 - Sep 21
7. Pear Tree Inn St. Louis Airport
Pear Tree Inn St. Louis AirportSt. Ann
Darren
NT$2,845
NT$3,350 total
includes taxes & fees
Sep 3 - Sep 4
8. Holiday Inn Express & Suites Kirksville - University Area by IHG
Holiday Inn Express & Suites Kirksville - University Area by IHGKirksville
David
NT$3,510
NT$3,977 total
includes taxes & fees
Sep 27 - Sep 28
9. Drury Inn & Suites St. Louis Airport
Drury Inn & Suites St. Louis AirportEdmundson
Hema
NT$3,636
NT$4,266 total
includes taxes & fees
Sep 6 - Sep 7
10. Hampton Inn & Suites St. Louis at Forest Park
Hampton Inn & Suites St. Louis at Forest ParkDogtown
rodnina
NT$4,382
NT$5,167 total
includes taxes & fees
Sep 7 - Sep 8
11. Best Western On The River
Best Western On The RiverHannibal
Devin S
NT$3,478
NT$4,012 total
includes taxes & fees
Sep 1 - Sep 2
12. Comfort Inn Sullivan
Comfort Inn SullivanSullivan
Kelly
NT$4,031
NT$4,393 total
includes taxes & fees
Sep 20 - Sep 21
13. Pinemark Inn & Suites
Pinemark Inn & SuitesSt. Clair
David
NT$4,251
NT$4,653 total
includes taxes & fees
Aug 31 - Sep 1
14. Hyatt Select St. Louis Airport
Hyatt Select St. Louis AirportWoodson Terrace
Paige
NT$3,478
NT$4,277 total
includes taxes & fees
Sep 6 - Sep 7
15. The Wildwood Hotel
The Wildwood HotelWildwood
Hailey
NT$2,789
NT$3,249 total
includes taxes & fees
Sep 30 - Oct 1
16. Quality Inn Foristell
Quality Inn ForistellForistell
Rebecca
NT$2,645
NT$2,987 total
includes taxes & fees
Sep 27 - Sep 28
17. Super 8 by Wyndham Kirksville-University Area
Super 8 by Wyndham Kirksville-University AreaKirksville
David
NT$2,024
NT$2,273 total
includes taxes & fees
Sep 13 - Sep 14
18. Holiday Inn Express & Suites Wentzville St Louis West by IHG
Holiday Inn Express & Suites Wentzville St Louis West by IHGWentzville
Derek
NT$4,269
NT$5,086 total
includes taxes & fees
Sep 6 - Sep 7
19. Drury Inn & Suites St. Louis St. Peters
Drury Inn & Suites St. Louis St. PetersSt. Peters
Melanie
NT$3,478
NT$3,998 total
includes taxes & fees
Sep 6 - Sep 7
20. Heritage Hotel Quincy
Heritage Hotel QuincyQuincy
Dustine
NT$2,216
NT$2,526 total
includes taxes & fees
Sep 1 - Sep 2
Vacation Rentals in Northeast Missouri
Cabin
Cannon Dam Cabins
Cannon Dam CabinsPerry
"Cozy and well equipped with everything we may have needed"
Apartment
White House at Grand Central
White House at Grand CentralGrand Center
"Staff was great and accommodating to my needs."
Apartment
Landing Furnished Apartments - Central West End
Landing Furnished Apartments - Central West EndCentral West End
"We booked a two bedroom for three people and the 2nd bedroom didn't have a bed! Contacted property, which was very responsive, but they couldn't do anything since we booked through Hotels. com"
Cottage
Walk to Tower Grove Park: St Louis Getaway
Walk to Tower Grove Park: St Louis GetawayTower Grove South
"great place and nice location"
Apartment
Spacious 3-Bedroom with King Bed
Spacious 3-Bedroom with King BedCentral West End
"Clean room nice area "
Vacation Home
Remodeled and Inviting Free EV
Remodeled and Inviting Free EVFenton
"It was nice to stay for a weekend but the neighborhood was nice I like the location where it wasn't too far from grocery stores food areas the only thing I was saying is it's nothing for the kids to do but overall I like it"
Apartment
Botanical Bliss | JZ Vacation Rentals
Botanical Bliss | JZ Vacation RentalsSouthwest Garden
Cottage
Peaceful Missouri Cabin Rental on 55 Acres!
Peaceful Missouri Cabin Rental on 55 Acres!Canton
"This is a great place to stay if you want to get away from the city. Rural enough to be quiet, but within easy driving distance to a city. Also perfect if you just want to stay on the property and really get away from city life, just bring your groceries. "
Vacation Home
Forest Park Oasis | JZ Vacation Rentals
Forest Park Oasis | JZ Vacation RentalsKings Oak
"Great property with plenty of space. Nice sized dining room table for dinner. Beautiful family room and fire place. Nicely decorated. "
Apartment
Lakefront Studio Guest Home on Hermann Wine Trail!
Lakefront Studio Guest Home on Hermann Wine Trail!New Haven
"Loved this property, very clean and well kept! Very pretty, lovely view. "
Apartment
Near Wineries: Country Condo in Stony Hill
Near Wineries: Country Condo in Stony HillNew Haven
"Clean and loved original architecture."
Cottage
Updated Missouri Cabin Rental on Large Farm
Updated Missouri Cabin Rental on Large FarmCanton
"The cabin rental was a great stay. Had some connection problems with the t.v. couldn't get past the check out date. The wifi was easy to hook up. The cabin was clean and smelled fresh. Did have some problems with ants on the countertop. Great place to stay, enjoyed our visit."
Apartment
St Louis Retreat ~ 1 Mi to Botanical Garden
St Louis Retreat ~ 1 Mi to Botanical GardenShaw
"great location, peaceful and beautiful home!"
Cottage
Close to Vineyards: Updated New Haven Retreat!
Close to Vineyards: Updated New Haven Retreat!New Haven
"Very clean and relaxing environment!! "
Save an average of 15% on thousands of hotels when you're signed in
Stay near popular Northeast Missouri attractions
Photo by Carl Guttovz
Busch Stadium
9.4/10 (4,850 reviews)
Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's acclaimed art scene or attend a baseball game.
Photo by Jeff White
St. Louis Zoo
9.2/10 (4,367 reviews)
In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world.
Enterprise Center
8.8/10 (1,597 reviews)
Catch an event at Enterprise Center during your trip to St. Louis. Experience the area's acclaimed art scene or attend a baseball game.
Dome at America’s Center
8.4/10 (1,229 reviews)
Catch an event at Dome at America’s Center during your trip to St. Louis. Experience the area's great live music and fascinating museums.
Forest Park
9.2/10 (3,389 reviews)
Nature, history and cultural institutions come together in one of the United States’ largest urban parks, which buzzes with St. Louis’ dynamic community spirit.
St. Louis University
8.6/10 (526 reviews)
Explore the campus of St. Louis University as part of your travels around St. Louis. Wander around the area's picturesque gardens or experience its fascinating museums.
City Museum
9.0/10 (3,209 reviews)
This quirky children’s museum invites visitors to crawl through whales, climb into tree houses and whiz down three-story slides.
America's Center Convention Complex
8.8/10 (306 reviews)
Learn about the events happening at America's Center Convention Complex during your trip to St. Louis. Experience the area's fascinating museums and acclaimed art scene.
Learn more about Northeast Missouri
Great live music, sports teams, and popular sights from St. Louis Zoo to St. Louis Union Station—explore Northeast Missouri, a family-friendly destination also known for its theaters.
See all hotels in Northeast Missouri
Top Northeast Missouri Hotel Reviews
Hollywood Casino & Hotel St. Louis
10/10 Excellent
"All good, clean quiet perfect after concert location"
Clayton Plaza Hotel & Extended Stay
10/10 Excellent
"Clean room, great staff, great location!"
Pear Tree Inn St. Louis Near Union Station
8/10 Good
"Room was clean and hotel was quiet and is in an easy and convenient area downtown."
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
10/10 Excellent
"We stay every time we come down in a convenient area"
Pear Tree Inn St. Louis Airport
10/10 Excellent
"I needed a place close to St Louis airport that was inexpensive clean, comfortable and safe. I got all of these things and will stay here again"
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
8/10 Good
"Neat niche property in the heart of downtown StL. Definitely not a luxury stay, but fun. Easy to get to"
Ameristar Casino Resort and Spa
8/10 Good
"All went well room clean, staff outstanding"
The Royal Sonesta Chase Park Plaza St. Louis
10/10 Excellent
"Staff went above and beyond to make sure we were taken care of!"
Hilton St. Louis at the Ballpark
8/10 Good
"Our room was over $300 a night and it had paint chipping everywhere and needed repairs. It was clean just out of date."
More cheap stays in Northeast Missouri
Motel 6 Hazelwood, MO
5781 Campus Ct Hazelwood MO
NT$1,908
NT$2,332 total
Sep 1 - Sep 2
includes taxes & fees
Days Inn and Suites by Wyndham St. Louis/Westport Plaza
1970 Craig Rd Maryland Heights MO
NT$2,150
NT$2,494 total
Sep 1 - Sep 2
includes taxes & fees
Best Western St. Louis Inn
6224 Heimos Industrial Park Dr St. Louis MO
NT$2,378
NT$2,734 total
Sep 17 - Sep 18
includes taxes & fees
Pear Tree Inn St. Louis Arnold
1201 Drury Ln Arnold MO
NT$2,845
NT$3,289 total
Sep 3 - Sep 4
includes taxes & fees
Pear Tree Inn St. Louis Airport
10810 Pear Tree Ln St. Ann MO
NT$2,845
NT$3,350 total
Sep 3 - Sep 4
includes taxes & fees
9.2/10 Wonderful! (3,209 reviews)
Tru By Hilton St. Louis Downtown
1221 Locus Street St. Louis MO
NT$3,085
NT$3,608 total
Sep 6 - Sep 7
includes taxes & fees
Hotels in Northeast Missouri with star-rating
5 Star Hotels
1 properties
4 Star Hotels
53 properties
3 Star Hotels
190 properties
2 Star Hotels
201 properties
Explore a world of travel with Expedia
- Golf Hotels in Canton
- Marceline Hotels
- Hotels with an Indoor Pool in Macon
- Palmyra Hotels
- Hotels with Bars in Hannibal
- Hotels with smoking rooms in Hannibal
- Hotels near Sawyer's Creek Fun Park
- Shelbina Hotels
- Stoutsville Hotels
- Hotels near Cooper's Oak Winery
- Resorts & Hotels with Spas in Perry
- Rush Hill Hotels
- Golf Hotels in Hannibal
- Vandalia Hotels
- Hotel with a Concierge Hotels in Macon
- Golf Hotels in Moberly
- Memphis Hotels
- Pet-Friendly Hotels in Hannibal
- Hotels with Hot Tubs in Macon
- Hotels near Molly Brown Museum and Home
- Brookfield Hotels
- Macon Hotels
- Hannibal Hotels
- Hotels with Bars in Rutledge
- Perry Hotels
- Hotels near Rockcliffe Mansion
- Saverton Hotels
- Hotels near Mark Twain Casino
- Pet-Friendly Hotels in Monroe City
- Moberly Hotels
- Kirksville Hotels
- Hotels near Magic City Line Mini Train
- Hotels near Jim's Journey: The Huck Finn Freedom Center
- B&B in Memphis
- 4 Star Hotels in Hannibal
- Hotels near Truman State University
- Cheap Hotels in New Cambria
- Luxury Hotels in Rutledge
- Kahoka Hotels
- Romantic Hotels in Hannibal
- Hotels near Heritage Hills Golf Course
- Marriott Hotels & Resorts in Hannibal
- Flights from St. Petersburg (PIE) to Kirksville (IRK)
- Flights to Shelbina
- Flights from Novinger
- Flights from Kirksville Municipal
- Flights from Shelbina
- Flights from Neuquén (NQN) to Kirksville (IRK)
- Flights from Jacobabad (JAG) to Kirksville (IRK)
- Flights from Burbank (BUR) to Kirksville (IRK)
- Flights from Puebla (PBC) to Kirksville (IRK)
- Flights from Akron (CAK) to Kirksville (IRK)
- Flights from Hannibal
- Flights from Tupelo (TUP) to Kirksville (IRK)
- Flights from Carbondale (MDH) to Kirksville (IRK)
- Flights to Palmyra
- Flights from Cape Girardeau (CGI) to Kirksville (IRK)
- Flights from Maywood
- Flights to Hannibal
- Flights from San Diego (SAN) to Kirksville (IRK)
- Flights from Hanoi (HAN) to Kirksville (IRK)
- Flights to Ethel
- Flights to Memphis
- Flights from Appleton (ATW) to Kirksville (IRK)
- Flights from Old Crow (YOC) to Kirksville (IRK)
- Flights from Takapoto (TKP) to Kirksville (IRK)
- Flights from Rutledge
- Flights from Flint (FNT) to Kirksville (IRK)
- Flights from Chennai (MAA) to Kirksville (IRK)
- Flights from Waukesha (UES) to Kirksville (IRK)
- Flights from Dothan (DHN) to Kirksville (IRK)
- Flights from Chattanooga (CHA) to Kirksville (IRK)
- Flights from Memphis
- Truman State University
- Hannibal Vacations
- Visit Holliday
- Visit Shelbina
- Magic City Line Mini Train
- Mark Twain Casino
- Kahoka Vacations
- Visit Stoutsville
- Visit La Grange
- Jim's Journey: The Huck Finn Freedom Center
- Visit Gibbs
- Mark Twain Memorial Lighthouse
- Memphis Vacations
- Visit La Plata
- Visit Callao
- Visit Hannibal
- Visit Lentner
- Budget Rental Cars in Holliday
- Thrifty Car Rental Rental Cars in Kirksville Municipal
- Car rental Monroe City
- First-Car Rental Cars in Taylor
- Budget Rental Cars in Taylor
- Dollar Rent A Car Rental Cars in Granger
- Top Rent a Car Rental Cars in Edina
- Rental cars Kirksville Municipal airport
- Thrifty Car Rental Rental Cars in Palmyra
- Car rental Hannibal
