What is Mayo Clinic like?

Travelers will be sure to find plenty to entertain them in Scottsdale's Mayo Clinic neighborhood.

Where is the best place to stay in Mayo Clinic?

Based on Expedia customer reviews, Sonesta Select Scottsdale at Mayo Clinic Campus is the highest ranked property in Mayo Clinic. This hotel offers a restaurant and an outdoor pool.

How many hotels will I be able to find in the Mayo Clinic area?

With 14 Expedia hotels and other accommodations in Mayo Clinic to choose from, this is a good starting point for exploring the greater Scottsdale area.

If I need to cancel my hotel reservation in Mayo Clinic, will I receive a refund?

Yes! Most hotel reservations are fully refundable if you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you booked a non-refundable reservation, you might be able to still cancel and receive a refund within a 24-hour period of booking. Add dates, click "Search", then use the filter option "fully refundable" to view the best deals in Mayo Clinic.

Where can I learn more about changing or cancelling my trip to Mayo Clinic?

For more information about updating your trip to Mayo Clinic or cancelling it, go to https://www.expedia.com/service/ .

What is there to do around this Scottsdale neighborhood?

A few places to visit in the area around Mayo Clinic include Eagle Mountain Golf Course, Golf Club at Eagle Mountain, and SunRidge Canyon Golf Club. Make a stop at Talking Stick Resort Casino and OdySea Aquarium while you're sightseeing around the area.

Top Mayo Clinic Hotels

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Our top choices for Mayo Clinic hotels

A hotel courtyard with a central pathway, potted plants, and a building with multiple balconies and windows.

1. Sonesta Select Scottsdale at Mayo Clinic Campus

Mayo Clinic

Michael

NT$3,238 total

includes taxes & fees

Oct 15 - Oct 16

A hotel room with two beds, a desk with a chair, a TV, and a lamp.

2. Comfort Suites Scottsdale Talking Stick Entertainment District

9.7 km from Mayo Clinic

LAURA

NT$3,964 total

includes taxes & fees

Oct 25 - Oct 26

A modern infinity pool with a view of mountains and a sunset.

3. Talking Stick Resort

9 km from Mayo Clinic

Meghan Rebbecca

NT$8,453 total

includes taxes & fees

Nov 8 - Nov 9

A hotel lobby with a reception desk, seating area, and a large wall mural.

4. La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

Central Scottsdale, 9 km from Mayo Clinic

Paul

NT$3,062 total

includes taxes & fees

Oct 25 - Oct 26

A Holiday Inn Express & Suites reception desk with a modern design, including a digital display and a sign above the desk.

5. Holiday Inn Express Hotel & Suites Phoenix North Scottsdale by IHG

20.2 km from Mayo Clinic

Than

NT$5,986 total

includes taxes & fees

Oct 15 - Oct 16

An outdoor seating area with sofas, tables, and umbrellas, featuring a fire feature in the center.

6. Hyatt Place Scottsdale - North

14.2 km from Mayo Clinic

Ted

NT$4,748 total

includes taxes & fees

Oct 25 - Oct 26

A water park with a multi-level water slide, palm trees, and a pool area with lounge chairs.

7. Holiday Inn Club Vacations Scottsdale Resort by IHG

13.3 km from Mayo Clinic

Michael

NT$9,788 total

includes taxes & fees

Oct 28 - Oct 29

A spacious lobby with a large seating area, a reception desk, and artwork on the walls.

8. Best Western Plus Scottsdale Thunderbird Suites

Thunderbird Industrial Airpark, 12.3 km from Mayo Clinic

Susan

NT$4,541 total

includes taxes & fees

Nov 1 - Nov 2

A cluster of modern, multi-story buildings with a river in the foreground.

9. Inn at Eagle Mountain

3 km from Mayo Clinic

Shelby

NT$4,820 total

includes taxes & fees

Oct 25 - Oct 26

A modern outdoor lounge area with sofas, chairs, and a glass-top coffee table with a fire feature.

10. Hyatt House North Scottsdale

14.2 km from Mayo Clinic

Slyqavious

NT$4,912 total

includes taxes & fees

Oct 21 - Oct 22

A courtyard with outdoor seating and a fire pit, surrounded by a building with multiple windows and doors.

11. Aiden by Best Western Scottsdale North

8.8 km from Mayo Clinic

Ioana G

NT$3,665 total

includes taxes & fees

Oct 14 - Oct 15

An outdoor dining area with wicker furniture and candles, overlooking a well-maintained garden and buildings.

12. Sonesta Suites Scottsdale Gainey Ranch

12.4 km from Mayo Clinic

Cindy

NT$6,332 total

includes taxes & fees

Oct 31 - Nov 1

A modern hotel lobby with a seating area, a staircase, and a reception desk.

13. Hampton Inn Phoenix-Airport North

23.2 km from Mayo Clinic

Jodi L

NT$4,265 total

includes taxes & fees

Nov 1 - Nov 2

A hotel room with a bed, desk, chair, and two bedside tables with lamps.

14. Fountain Park Hotel, BW Signature Collection

7.2 km from Mayo Clinic

Guadalupe

NT$3,576 total

includes taxes & fees

Oct 13 - Oct 14

A modern breakfast area with a sign reading "EXPRESS START BREAKFAST" and a "GOOD MORNING" sign on the wall.

15. Holiday Inn Express & Suites Phoenix - Airport North by IHG

23.2 km from Mayo Clinic

Jerry

NT$4,368 total

includes taxes & fees

Nov 1 - Nov 2

A modern hotel room with a grey sofa, a round table, a bed with white linens, a large abstract painting, a floor lamp, and a window with curtains.

16. Hyatt Place Tempe Phoenix Airport

23.5 km from Mayo Clinic

dularie

NT$4,225 total

includes taxes & fees

Oct 25 - Oct 26

An indoor water park with slides, a wave pool, and seating areas.

17. Great Wolf Lodge Arizona

10.3 km from Mayo Clinic

Dejanira

NT$5,938 total

includes taxes & fees

Oct 26 - Oct 27

A spacious lobby with a fireplace, seating areas, and large windows.

18. Hilton Garden Inn Phoenix Airport North

24.2 km from Mayo Clinic

Aaliyah

NT$4,173 total

includes taxes & fees

Oct 31 - Nov 1

A Courtyard by Marriott hotel entrance with palm trees, a covered walkway, and a well-lit facade.

19. Courtyard Phoenix North by Marriott

30.1 km from Mayo Clinic

Marco Antonio

NT$4,191 total

includes taxes & fees

Oct 31 - Nov 1

An outdoor seating area with sofas, chairs, and a fire pit.

20. Home2 Suites by Hilton Phoenix Airport North, AZ

23.1 km from Mayo Clinic

Edward L

NT$4,265 total

includes taxes & fees

Nov 1 - Nov 2

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Where to stay in Mayo Clinic

Find the best Mayo Clinic areas and neighborhoods for the activities you enjoy most.

A cityscape with prominent buildings including a Chase bank and The Arizona Republic building.

Downtown Phoenix

A true urban neighborhood, Downtown Phoenix boasts major sports venues like Chase Field and Footprint Center, as well as cultural attractions such as the Arizona Science Center and Phoenix Art Museum. Easily accessible via Valley Metro Light Rail, enjoy walkable streets, friendly cafes, and local businesses.

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A fountain with three horses, surrounded by red flowers and storefronts.

Old Town

Old Town is known for its popular shops, and you can see some sights in the area like Scottsdale Waterfront and Western Spirit: Scottsdale's Museum of the West.

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A hiker on a rocky trail with mountains in the background.

Rio Verde Foothills

If you're looking for some top things to see and do in Rio Verde Foothills and surrounding area, you can visit Golf Club Scottsdale and Tom's Thumb Trail.

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A rocky hill with palm trees and a body of water.

Camelback East

Adjacent to Paradise Valley and Scottsdale, Camelback East Village boasts two main cores and sits between Piestewa Peak and Camelback Mountain. Explore the vibrant 24th Street and Camelback Road or 44th Street and Van Buren Street areas.

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A mountainous landscape with a city in the valley below.

North Phoenix

While you're in North Phoenix, take in top sights like Reach 11 Sports Complex and jump on the metro at 19th Avenue/ Dunlap Station to see more of the city.

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Top Mayo Clinic Hotel Reviews

SureStay By Best Western Phoenix Airport

10/10 Excellent

"The property was modern, clean, just the basics, but that's what we needed, and the price was excellent, close to the airport. The staff was amazing. All in all, highly recommend for a short stay."