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Discover 12,836 Mayo Clinic hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.
Our top choices for Mayo Clinic hotels

Holiday Inn Express & Suites Phoenix - Airport North by IHG
Holiday Inn Express & Suites Phoenix - Airport North by IHG

Holiday Inn Express Hotel & Suites Phoenix-Airport by IHG
Holiday Inn Express Hotel & Suites Phoenix-Airport by IHG

The McCormick Scottsdale
The McCormick Scottsdale

Sonesta Select Scottsdale at Mayo Clinic Campus
Sonesta Select Scottsdale at Mayo Clinic Campus

Days Inn & Suites by Wyndham Mesa Near Phoenix
Days Inn & Suites by Wyndham Mesa Near Phoenix

La Quinta Inn & Suites by Wyndham Mesa Superstition Springs
La Quinta Inn & Suites by Wyndham Mesa Superstition Springs
Where to stay in Mayo Clinic

Downtown Phoenix
A true urban neighborhood, Downtown Phoenix boasts major sports venues like Chase Field and Footprint Center, as well as cultural attractions such as the Arizona Science Center and Phoenix Art Museum. Easily accessible via Valley Metro Light Rail, enjoy walkable streets, friendly cafes, and local businesses.

Old Town
Old Town is known for its popular shops, and you can see some sights in the area like Scottsdale Waterfront and Western Spirit: Scottsdale's Museum of the West.

Camelback East
Adjacent to Paradise Valley and Scottsdale, Camelback East Village boasts two main cores and sits between Piestewa Peak and Camelback Mountain. Explore the vibrant 24th Street and Camelback Road or 44th Street and Van Buren Street areas.
Central Scottsdale
While visiting Central Scottsdale, you might make a stop by sights like Scottsdale Ranch Park and Starfire Golf Club at Scottsdale Country Club.

East Mesa
While you're in East Mesa, take in top sights like Salt River Tubing and jump on the metro at Superstition Springs Transit Center to see more of the city.
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Hotels in top Phoenix neighborhoods
- Hotels in Downtown Phoenix
- Hotels in Old Town
- Hotels in Camelback East
- Hotels in Central Scottsdale
- Hotels in East Mesa
- Hotels in Paradise Valley Village
- Hotels in North Mountain
- Hotels in Deer Valley
- Hotels in Paradise Valley Village
- Hotels in Downtown Scottsdale
- Hotels in Desert Ridge
- Hotels in South Mountain
- Hotels in Desert View Village
- Hotels in Ahwatukee Foothills
- Hotels in Alhambra
- Hotels in Encanto
- Hotels in Pinnacle Peak
- Hotels in South Tempe
- Hotels in Kierland
- Hotels in Anthem
Hotels near popular Phoenix Attractions
- Hotels near Mayo Clinic Scottsdale
- Hotels near Arizona State University
- Hotels near Phoenix Convention Center
- Hotels near Chase Field
- Hotels near Talking Stick Resort Casino
- Hotels near Mayo Clinic Hospital
- Hotels near PHX Arena
- Hotels near Kierland Commons
- Hotels near Biltmore Fashion Park
- Hotels near Camelback Mountain
More Accommodation Types in Mayo Clinic
Mayo Clinic Hotels by Star Rating
Explore more hotels
- SureStay Hotel by Best Western Phoenix Airport
- Mountain Shadows Resort Scottsdale
- Marriott Phoenix Resort Tempe at The Buttes
- Aloft Phoenix Airport
- Hampton Inn & Suites Phoenix Downtown
- The Phoenician, a Luxury Collection Resort, Scottsdale
- Country Inn & Suites by Radisson, Phoenix Airport, AZ
- Radisson Hotel Phoenix Airport
- Scottsdale Camelback Resort
- JW Marriott Phoenix Desert Ridge Resort & Spa
- Hilton Phoenix Airport
- Hyatt Regency Phoenix
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