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Jul 18 - Jul 19
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Discover 13,194 Mayo Clinic hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Sonesta Select Scottsdale at Mayo Clinic Campus
Lobby lounge

Sonesta Select Scottsdale at Mayo Clinic Campus

3.0 star property
8.2 out of 10, Very Good, (1010)
"It was a great place to stay and very close to the Mayo Clinic where we were going Love the big TV and the staff was great."
The price is NT$2,225
NT$2,536 total
includes taxes & fees
Jul 26 - Jul 27
Sonesta Select Scottsdale at Mayo Clinic Campus
Best Western Apache Junction Inn
Lobby

Best Western Apache Junction Inn

2.5 star property
8.8 out of 10, Excellent, (617)
"The pool and breakfast were nice. "
The price is NT$3,530
NT$3,936 total
includes taxes & fees
Jul 31 - Aug 1
Best Western Apache Junction Inn
Wekopa Casino Resort
Terrace/patio

Wekopa Casino Resort

4.0 star property
9.2 out of 10, Wonderful, (1001)
"Great stay!!"
Wekopa Casino Resort
Fountain Park Hotel, BW Signature Collection
Reception

Fountain Park Hotel, BW Signature Collection

3.0 star property
8.8 out of 10, Excellent, (1002)
"Great stay!! Loved this place. "
The price is NT$2,324
NT$2,653 total
includes taxes & fees
Aug 9 - Aug 10
Fountain Park Hotel, BW Signature Collection
Westgate Painted Mountain Golf Resort
Property grounds

Westgate Painted Mountain Golf Resort

4.0 star property
8.4 out of 10, Very Good, (1000)
"Great location and amenities—stayed there twice now."
The price is NT$2,515
NT$2,874 total
includes taxes & fees
Jul 31 - Aug 1
Westgate Painted Mountain Golf Resort
Best Western Superstition Springs Inn
Standard Room, 2 Queen Beds, Non Smoking, Refrigerator & Microwave | 1 bedroom, desk, laptop workspace, blackout drapes

Best Western Superstition Springs Inn

2.5 star property
7.8 out of 10, Good, (933)
"Awesome place "
The price is NT$2,471
NT$2,824 total
includes taxes & fees
Jul 31 - Aug 1
Best Western Superstition Springs Inn
Country Inn & Suites by Radisson, Mesa, AZ
Lobby

Country Inn & Suites by Radisson, Mesa, AZ

2.5 star property
7.8 out of 10, Good, (1003)
"Great place! Friendly staff and it was quite and clean"
The price is NT$2,526
NT$2,886 total
includes taxes & fees
Aug 3 - Aug 4
Country Inn & Suites by Radisson, Mesa, AZ
SureStay Plus by Best Western Mesa Superstition Springs
Exterior

SureStay Plus by Best Western Mesa Superstition Springs

2.5 star property
8.4 out of 10, Very Good, (1506)
"Great place for the price"
The price is NT$2,030
NT$2,320 total
includes taxes & fees
Jul 28 - Jul 29
SureStay Plus by Best Western Mesa Superstition Springs
La Quinta Inn & Suites by Wyndham Mesa Superstition Springs
Gazebo

La Quinta Inn & Suites by Wyndham Mesa Superstition Springs

3.0 star property
8.2 out of 10, Very Good, (1673)
"It was a great stay "
The price is NT$2,356
NT$2,693 total
includes taxes & fees
Jul 20 - Jul 21
La Quinta Inn & Suites by Wyndham Mesa Superstition Springs
Inn at Eagle Mountain
Mountain view

Inn at Eagle Mountain

3.5 star property
8.8 out of 10, Excellent, (1006)
"Very nice location, friendly staff, and perfect for our family. "
Inn at Eagle Mountain
Superior Suites Phoenix Mesa
Reception

Superior Suites Phoenix Mesa

2.0 star property
7.0 out of 10, Good, (1002)
"Friendly staff"
The price is NT$1,736
NT$2,101 total
includes taxes & fees
Jul 28 - Jul 29
Superior Suites Phoenix Mesa
The Azure Hotel
Reception

The Azure Hotel

2.5 star property
8.8 out of 10, Excellent, (1471)
"Great room and bathroom. Staff was helpful and the area was quiet with easy parking!"
The Azure Hotel
Hilton Vacation Club Scottsdale Links Resort
Exterior

Hilton Vacation Club Scottsdale Links Resort

3.5 star property
9.2 out of 10, Wonderful, (1002)
"Absolutely wonderful property! I would stay there again anytime!"
The price is NT$2,801
NT$4,065 total
includes taxes & fees
Aug 3 - Aug 4
Hilton Vacation Club Scottsdale Links Resort
Talking Stick Resort
Exterior

Talking Stick Resort

4.0 star property
9.2 out of 10, Wonderful, (3533)
"Great stay "
Talking Stick Resort
Sonesta Simply Suites Phoenix Scottsdale
Outdoor pool

Sonesta Simply Suites Phoenix Scottsdale

2.5 star property
8.0 out of 10, Very Good, (966)
"Great stay!"
The price is NT$2,225
NT$2,536 total
includes taxes & fees
Jul 21 - Jul 22
Sonesta Simply Suites Phoenix Scottsdale
Aiden by Best Western Scottsdale North
Outdoor pool

Aiden by Best Western Scottsdale North

3.0 star property
9.0 out of 10, Wonderful, (1003)
"Clean and staff was friendly "
The price is NT$2,339
NT$2,665 total
includes taxes & fees
Jul 20 - Jul 21
Aiden by Best Western Scottsdale North
La Quinta Inn & Suites by Wyndham Phoenix Scottsdale
Gazebo

La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

3.0 star property
8.8 out of 10, Excellent, (1611)
"Super fast check in and great staff."
The price is NT$2,209
NT$2,517 total
includes taxes & fees
Jul 20 - Jul 21
La Quinta Inn & Suites by Wyndham Phoenix Scottsdale
Sheraton Desert Oasis Villas, Scottsdale
Outdoor pool

Sheraton Desert Oasis Villas, Scottsdale

3.5 star property
9.2 out of 10, Wonderful, (882)
"Was larger than expected and the villas were very nice. Great atmosphere around the pool and I would definitely recommend a stay at this location"
The price is NT$3,736
NT$4,258 total
includes taxes & fees
Aug 2 - Aug 3
Sheraton Desert Oasis Villas, Scottsdale
Days Inn & Suites by Wyndham Mesa Near Phoenix
Room, 2 Queen Beds, Accessible, Non Smoking | Pillowtop beds, in-room safe, desk, iron/ironing board

Days Inn & Suites by Wyndham Mesa Near Phoenix

3.0 star property
9.0 out of 10, Wonderful, (1740)
"would recommend staying here again "
The price is NT$2,176
NT$2,487 total
includes taxes & fees
Jul 20 - Jul 21
Days Inn & Suites by Wyndham Mesa Near Phoenix
Hilton Vacation Club Scottsdale Villa Mirage
Outdoor pool, sun loungers

Hilton Vacation Club Scottsdale Villa Mirage

3.5 star property
8.4 out of 10, Very Good, (1014)
"The room size is great for families Everything was very clean. Great stay "
The price is NT$2,095
NT$3,260 total
includes taxes & fees
Aug 9 - Aug 10
Hilton Vacation Club Scottsdale Villa Mirage
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Mayo Clinic

Find the best Mayo Clinic areas and neighborhoods for the activities you enjoy most.
Downtown Phoenix which includes signage and night scenes
Downtown Phoenix map

Downtown Phoenix

3 out of top 10 points of interest in this area

A true urban neighborhood, Downtown Phoenix boasts major sports venues like Chase Field and Footprint Center, as well as cultural attractions such as the Arizona Science Center and Phoenix Art Museum. Easily accessible via Valley Metro Light Rail, enjoy walkable streets, friendly cafes, and local businesses.

Old Town
Old Town map

Old Town

Old Town is known for its popular shops, and you can see some sights in the area like Scottsdale Waterfront and Western Spirit: Scottsdale's Museum of the West.

Papago Park featuring desert views as well as a small group of people
Camelback East map

Camelback East

2 out of top 10 points of interest in this area

Adjacent to Paradise Valley and Scottsdale, Camelback East Village boasts two main cores and sits between Piestewa Peak and Camelback Mountain. Explore the vibrant 24th Street and Camelback Road or 44th Street and Van Buren Street areas.

East Mesa map

East Mesa

While you're in East Mesa, take in top sights like Salt River Tubing and jump on the metro at Superstition Springs Transit Center to see more of the city.

Deer Valley showing a sunset, desert views and landscape views
Deer Valley map

Deer Valley

Nestled in northwestern Phoenix, Deer Valley boasts the Adobe Dam Regional Park, offering a sports complex, golf course, and kart racing track. Explore the Deer Valley Petroglyph Preserve, home to over 1500 petroglyphs, for a unique experience.

Top Mayo Clinic Hotel Reviews

Talking Stick Resort

Talking Stick Resort

10/10 Excellent
"Casino is large, poker room is big with lots of tables, very well laid out. Absolutely one of the nicest hotels in Scottsdale. The casino gaming is a plus. "
Henry 1-night trip
Posted 13 hours ago
Talking Stick Resort

Frequently asked questions

What is Mayo Clinic like?

Travelers will be sure to find plenty to entertain them in Scottsdale's Mayo Clinic neighborhood.

Where is the best place to stay in Mayo Clinic?

Based on Expedia customer reviews, Sonesta Select Scottsdale at Mayo Clinic Campus is the highest ranked property in Mayo Clinic. This hotel offers a restaurant and an outdoor pool.

How many hotels will I be able to find in the Mayo Clinic area?

With 14 Expedia hotels and other accommodations in Mayo Clinic to choose from, this is a good starting point for exploring the greater Scottsdale area.

If I need to cancel my hotel reservation in Mayo Clinic, will I receive a refund?

Yes! Most hotel reservations are fully refundable if you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you booked a non-refundable reservation, you might be able to still cancel and receive a refund within a 24-hour period of booking. Add dates, click "Search", then use the filter option "fully refundable" to view the best deals in Mayo Clinic.

Where can I learn more about changing or cancelling my trip to Mayo Clinic?

For more information about updating your trip to Mayo Clinic or cancelling it, go to https://www.expedia.com/service/.

What is there to do around this Scottsdale neighborhood?

A few places to visit in the area around Mayo Clinic include Eagle Mountain Golf Course, Golf Club at Eagle Mountain, and SunRidge Canyon Golf Club. Make a stop at Talking Stick Resort Casino and OdySea Aquarium while you're sightseeing around the area.