The Best Hotels Closest to Lewis and Clark Interpretive Center in St. Louis for 2026

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Our top choices for Lewis and Clark Interpretive Center hotels

A spacious lobby with a high ceiling, large windows, and a variety of seating options including sofas and chairs.

A spacious indoor area with a large table and chairs, a sofa, and a staircase leading to an upper level.

A hotel room with a large bed, a desk, a chair, and a television.

A restaurant with a brick wall, large windows, and a seating area with tables and chairs.

1. Drury Inn & Suites St. Louis Collinsville

15.4 km from Lewis and Clark Interpretive Center

Cheryl

NT$3,128

NT$3,597 total

includes taxes & fees

Nov 1 - Nov 2

A hotel room with two beds, a desk, a chair, and a wall-mounted lamp.

A breakfast station with self-service options, a sign indicating hot food availability, and a digital menu board displaying breakfast items.

An indoor swimming pool with a lifeguard on duty sign, a pool lift, and chairs around the pool area.

2. Holiday Inn Express Troy by IHG

18 km from Lewis and Clark Interpretive Center

Tammy

NT$3,767

NT$4,181 total

includes taxes & fees

Nov 1 - Nov 2

An indoor swimming pool with a lifeguard chair, a lifebuoy, and a mural of a beach scene.

A hotel room with a bed, a desk, a chair, a lamp, a mirror, and a television.

A reception desk with a wooden counter, two HP laptops, a telephone, and a framed black and white photo on the wall.

A breakfast area with a wooden counter, a microwave, and a coffee machine.

3. Super 8 by Wyndham Troy IL/St. Louis Area

17.8 km from Lewis and Clark Interpretive Center

Jacqueline

NT$2,035

NT$2,259 total

includes taxes & fees

Oct 18 - Oct 19

A modern living room with a stone fireplace, a reception desk, and a large window.

An indoor swimming pool with clear blue water, surrounded by lounge chairs and tables, large windows with a view of trees, and a tiled floor.

A Fairfield by Marriott hotel with a modern design, featuring a covered entrance and multiple floors.

A modern living room with a stone fireplace, green and beige sofas, a round coffee table, and large windows offering a view of trees.

4. Fairfield Inn & Suites St. Louis Pontoon Beach/Granite City

6.2 km from Lewis and Clark Interpretive Center

Sabra

NT$3,563

NT$3,954 total

includes taxes & fees

Nov 1 - Nov 2

A hotel room with a bed, a desk with a TV, a chair, a sofa, and a window with curtains.

A modern kitchen area with a waffle station, coffee machine, and waffle maker.

A modern kitchen with a built-in microwave, a white countertop, and a sink.

A gym with treadmills, a bench, dumbbells, and a mirror.

5. Hampton Inn & Suites St. Louis/Alton

14 km from Lewis and Clark Interpretive Center

Kathy

NT$4,163

NT$4,744 total

includes taxes & fees

Oct 18 - Oct 19

A hotel lobby with blue seating, a flat-screen TV, and a fireplace.

A hotel room with a large bed, two bedside tables, a desk, and a chair.

A spacious dining area with high tables and booths, large windows, and a view of greenery outside.

An indoor swimming pool with clear water, surrounded by lounge chairs and a tiled deck.

6. Comfort Inn Edwardsville - St. Louis

9.4 km from Lewis and Clark Interpretive Center

Christina

NT$3,039

NT$3,495 total

includes taxes & fees

Nov 1 - Nov 2

An outdoor patio with a circular fire pit, seating, and a grill area.

A modern kitchen with stainless steel appliances, wooden cabinets, and a countertop with a coffee maker and mugs.

An indoor swimming pool with clear water, a 15-meter length marker, and a 5-foot depth marker. There are lounge chairs and a table with chairs around the pool.

A multi-story hotel with a covered entrance and a sign reading "Towneplace Suites by Marriott".

7. TownePlace Suites by Marriott St. Louis Edwardsville, IL

10.9 km from Lewis and Clark Interpretive Center

Jamie

NT$5,427

NT$6,240 total

includes taxes & fees

Oct 25 - Oct 26

A hotel room with a bed, a desk with a television, a chair, a desk lamp, and a wall-mounted rack with keys.

A swimming pool with a clear blue water, surrounded by lounge chairs and a sunbed.

A modern office space with a desk, computer, and a large window.

8. Red Roof Inn St Louis - Troy, IL

18 km from Lewis and Clark Interpretive Center

Deanise

NT$2,069

NT$2,296 total

includes taxes & fees

Oct 18 - Oct 19

A hotel entrance with a covered driveway and a parking area.

A hotel lobby with striped armchairs, a round coffee table, a sofa, and a clock on the wall.

A hotel room with two beds, a TV, a desk, and a chair.

A dining area with multiple tables and chairs, a kitchen in the background, and artwork on the walls.

9. Best Western Plus Parkway Hotel

13.9 km from Lewis and Clark Interpretive Center

Steve

NT$2,456

NT$2,799 total

includes taxes & fees

Oct 18 - Oct 19

A brick building with a wooden gazebo in front.

A statue of a Native American figure with a horse, a Route 66 sign, a map, and a clock on the wall.

A compact kitchen with a sink, microwave, and stove, a wooden cabinet, and a television mounted on the wall.

A spacious dining area with multiple round tables and chairs, a fireplace, and large windows with curtains.

10. Country Hearth Inn & Suites Edwardsville St. Louis

10.8 km from Lewis and Clark Interpretive Center

Kristy

NT$4,118

NT$4,735 total

includes taxes & fees

Oct 12 - Oct 13

A modern kitchen with marble countertops, a built-in coffee station, and a seating area with metal chairs and tables.

A hotel room with a large bed, a nightstand with a phone, and wall-mounted lights.

A motel with multiple floors, a parking lot, and a clear sky.

11. Days Inn by Wyndham Troy IL

18 km from Lewis and Clark Interpretive Center

Carol

NT$2,248

NT$2,494 total

includes taxes & fees

Oct 14 - Oct 15

A modern lobby with patterned armchairs, a fireplace, and a large TV on the wall.

A modern lobby with a blue patterned carpet, a white sofa, patterned armchairs, and a decorative mirror.

A garden with a stone wall, a wooden pergola, and yellow daffodils.

A lobby with a sofa, armchairs, a chandelier, decorative mirrors, and a fireplace.

12. Holiday Inn Express & Suites Edwardsville by IHG

10.9 km from Lewis and Clark Interpretive Center

Mary

NT$4,023

NT$4,625 total

includes taxes & fees

Nov 10 - Nov 11

A spacious dining area with high ceilings, multiple dining tables, and chairs.

A hotel room with a sofa, two chairs, a table, and a flat-screen TV mounted on the wall.

A Hampton Inn & Suites with a clear entrance, a parking lot, and a flagpole.

A hotel reception area with a wooden reception desk, a framed picture of a building, and a blue wall with framed items.

13. Hampton Inn & Suites St. Louis-Edwardsville

10.1 km from Lewis and Clark Interpretive Center

Tashae

NT$3,501

NT$3,920 total

includes taxes & fees

Oct 31 - Nov 1

A hotel lobby with a stone fireplace, a dining area with tables and chairs, and a colorful carpet.

A hotel room with a bed, a sofa, two small tables, a chair, and a painting on the wall.

A vending machine with snacks and drinks, a microwave, and a refrigerator.

A gym with exercise equipment, a bench, and a rack of dumbbells.

14. Fairfield Inn by Marriott St. Louis Collinsville, IL

15.3 km from Lewis and Clark Interpretive Center

David A.

NT$3,037

NT$3,492 total

includes taxes & fees

Oct 18 - Oct 19

A multi-story hotel with balconies, a parking lot with marked spaces, and a clear sky.

A long, straight corridor with a series of doors on one side and a black railing on the other.

A hotel room with two beds, each with a wooden headboard, white bedding, and a patterned bedspread.

A red door with a prohibition sign against tobacco, e-cigarettes, and cannabis.

15. Bel Air Motel

6.3 km from Lewis and Clark Interpretive Center

Tai

NT$2,442

NT$2,998 total

includes taxes & fees

Oct 12 - Oct 13

A buffet area with a wooden counter, various food items, and a coffee station.

A reception area with a wooden reception desk, a stone wall with a clock, and framed pictures on the wall.

A Comfort Inn hotel with a simple facade, a parking lot, and a clear sky in the background.

A hotel room with a sofa, a small table, a lamp, and a TV.

16. Comfort Inn Collinsville near St. Louis

15.3 km from Lewis and Clark Interpretive Center

Chessy

NT$3,193

NT$3,671 total

includes taxes & fees

Nov 1 - Nov 2

An outdoor patio area with multiple tables and chairs, surrounded by neatly trimmed bushes and a gravel path.

A parking area with electric vehicle charging stations, marked parking spaces, and a chain-link fence.

A modern building with a blue and white color scheme, labeled "The Great Rivers." It features a parking lot with several cars and a gas station in the foreground.

A hotel room with a bed, a sofa, a small table, and a painting on the wall.

17. The Great Rivers, an Ascend Collection Hotel

11.5 km from Lewis and Clark Interpretive Center

Jo Ann

NT$2,784

NT$3,173 total

includes taxes & fees

Nov 8 - Nov 9

A modern hotel room with a large bed, a blue chair, and a wall-mounted TV.

A modern hotel lobby with a kitchen area, multiple seating arrangements, and framed artwork on the walls.

A kitchen with a microwave, a refrigerator, and a coffee station.

18. Days Inn by Wyndham Collinsville/St. Louis

15.3 km from Lewis and Clark Interpretive Center

Gary

NT$1,900

NT$2,184 total

includes taxes & fees

Nov 9 - Nov 10

A cozy lounge area with leather seating, a wooden coffee table, and a fireplace.

A hotel bathroom with a large bathtub, a sofa, a microwave, and a desk with a lamp.

A hotel lobby with a beverage fridge, a television, and a seating area with a sofa and armchairs.

A hotel room with a bed, a sofa, a desk, and a chair.

19. Best Western Plus Pontoon Beach

6.8 km from Lewis and Clark Interpretive Center

Timothy

NT$3,304

NT$3,667 total

includes taxes & fees

Oct 18 - Oct 19

An outdoor patio area with wicker furniture, a stone fire pit, and potted plants.

A gym with exercise equipment, a television, and windows.

A spacious lobby with a large sofa, armchairs, and a coffee table. There is a reception desk with a computer and a large decorative mirror.

A hotel room with two beds, a desk with a lamp, a television, and a coffee maker.

20. DoubleTree by Hilton Collinsville - St. Louis

15.6 km from Lewis and Clark Interpretive Center

katie

NT$3,772

NT$4,337 total

includes taxes & fees

Oct 29 - Oct 30

View all properties

Compare popular hotels close to Lewis and Clark Interpretive Center

Property	Property class	Guest rating
Drury Inn & Suites St. Louis Collinsville	9.6 Exceptional 1,003 reviews	View
Holiday Inn Express Troy by IHG	9.4 Exceptional 842 reviews	View
Super 8 by Wyndham Troy IL/St. Louis Area	8.2 Very good 1,007 reviews	View
Fairfield Inn & Suites St. Louis Pontoon Beach/Granite City	9.2 Wonderful 534 reviews	View
Hampton Inn & Suites St. Louis/Alton	9.0 Wonderful 715 reviews	View

Top Lewis and Clark Interpretive Center Hotel Reviews

Drury Plaza Hotel St. Louis Union Station

10/10 Excellent

"Bed very comfortable, clean room, staff friendly and helpful. Good location. Food in evening was amazing. Breakfast buffet was good, about like other hotels as far as choices, nicely setup tho."

Drury Plaza Hotel St. Louis at the Arch

10/10 Excellent

"Clean room good breakfast"

Home2 Suites by Hilton St. Louis Downtown

10/10 Excellent

"My stay was welcoming and close to amenities. I enjoyed myself and will come again."

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

8/10 Good

"Rooms were a bit tired - could use an update. Curtains were broken and couldn’t close."

Tru By Hilton St. Louis Downtown

10/10 Excellent

"Beautiful hotel. Staff was amazing and super friendly! Loved that it was pet friendly and had wood floors! Dog park across the street was very convenient. The breakfast spread was great! Only complaint was I wish parking was included. $55 for valet garage parking otherwise parking is on the street and very limited. Not the hotels fault at all but the nightly activity outside of the hotel makes you lwary to leave your car parked on the street. They do have an armed security guard on site 24 hours that periodically does patrol outside the hotel. Luckily we were able to park pretty close"

21C Museum Hotel St Louis

10/10 Excellent

"Unique and beautiful hotel. Staff is efficient and friendly."

Days Inn by Wyndham Downtown St. Louis

10/10 Excellent

"it was good"

Other attractions near Lewis and Clark Interpretive Center

Lewis and Clark Confluence Tower

Bring a camera when you climb this tower, which offers fantastic views across the Mississippi River and provides insight into a fascinating piece of history.

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Lewis and Clark State Memorial Park

Explore the great outdoors at Lewis and Clark State Memorial Park, a lovely green space in Hartford. Discover the area's museums and monuments.

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Hartford Park

After visiting Hartford Park, make a plan to see the other sights and activities in Hartford. Discover the area's museums and monuments.

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Hartford City Hall

Hartford City Hall is just one of the places to see in Hartford, so why not enjoy the other things to explore during your travels? Amble around the area's riverfront or experience its museums.

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Jones-Confluence Point State Park

You can take time to visit Jones-Confluence Point State Park during your travels to West Alton. You can attend a sporting event while in the area.

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Dads Club Park

Explore the great outdoors at Dads Club Park, a lovely green space in South Roxana.

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South Roxana Dad's Club Park

South Roxana Dad's Club Park is just one of the places to see in South Roxana, so why not enjoy the other things to explore during your travels?

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Frequently asked questions

What's the area like around Lewis and Clark Interpretive Center?

Lewis and Clark Interpretive Center is located in a welcoming area of Hartford that travelers like for its sporting events. You'll find 12 hotels and other accommodations within a few miles for a convenient home base.

Where is the best place to stay close to Lewis and Clark Interpretive Center?

Hyatt Regency St. Louis at The Arch is one of the top choices for your stay based on our traveler data, and this hotel offers 3 restaurants and 2 bars. You'll find it 13 mi (20.9 km) from Lewis and Clark Interpretive Center. Other good options around the area include Super 8 by Wyndham St. Louis North and Drury Plaza Hotel St. Louis at the Arch.

How many hotels are there near Lewis and Clark Interpretive Center?

Expedia has 12 hotels and other accommodations a few miles from Lewis and Clark Interpretive Center.

If I need to cancel the hotel reservation for my stay near Lewis and Clark Interpretive Center, will I receive a refund?

Yes! The majority of hotel bookings are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you have a non-refundable reservation, you may still be able to cancel and be given a refund within 24 hours of your booking. Put your dates in and click on "Search", then filter by "fully refundable" to review the best deals near Lewis and Clark Interpretive Center.

Where can I learn more about changing or cancelling my trip in the area near Lewis and Clark Interpretive Center?

For additional details about rescheduling or cancelling your stay near Lewis and Clark Interpretive Center, click here.

What can I see and do near Lewis and Clark Interpretive Center?

You might spend a leisurely day outdoors at Lewis and Clark State Memorial Park and Dads Club Park. Create some family memories at CP Pinball and Saint Louis Zoo WildCare Park. Explore nature at Jones-Confluence Point State Park and Columbia Bottom Conservation Area.

Find hotels near Lewis and Clark Interpretive Center, St. Louis from NT$2,184

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Our top choices for Lewis and Clark Interpretive Center hotels

1. Drury Inn & Suites St. Louis Collinsville

2. Holiday Inn Express Troy by IHG

3. Super 8 by Wyndham Troy IL/St. Louis Area

4. Fairfield Inn & Suites St. Louis Pontoon Beach/Granite City

5. Hampton Inn & Suites St. Louis/Alton

6. Comfort Inn Edwardsville - St. Louis

7. TownePlace Suites by Marriott St. Louis Edwardsville, IL

8. Red Roof Inn St Louis - Troy, IL

9. Best Western Plus Parkway Hotel

10. Country Hearth Inn & Suites Edwardsville St. Louis

11. Days Inn by Wyndham Troy IL

12. Holiday Inn Express & Suites Edwardsville by IHG

13. Hampton Inn & Suites St. Louis-Edwardsville

14. Fairfield Inn by Marriott St. Louis Collinsville, IL

15. Bel Air Motel

16. Comfort Inn Collinsville near St. Louis

17. The Great Rivers, an Ascend Collection Hotel

18. Days Inn by Wyndham Collinsville/St. Louis

19. Best Western Plus Pontoon Beach

20. DoubleTree by Hilton Collinsville - St. Louis

Compare popular hotels close to Lewis and Clark Interpretive Center

Top Lewis and Clark Interpretive Center Hotel Reviews

Drury Plaza Hotel St. Louis Union Station

Drury Plaza Hotel St. Louis at the Arch

Home2 Suites by Hilton St. Louis Downtown

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Tru By Hilton St. Louis Downtown

21C Museum Hotel St Louis

Days Inn by Wyndham Downtown St. Louis

Other attractions near Lewis and Clark Interpretive Center

Lewis and Clark Confluence Tower

Lewis and Clark State Memorial Park

Hartford Park

Hartford City Hall

Jones-Confluence Point State Park

Dads Club Park

South Roxana Dad's Club Park

Frequently asked questions

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