Find Boutique Hotels in Lake City, SC

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Check availability on Lake City Boutique Hotels

Tonight
Dec 26 - Dec 27
Tomorrow
Dec 27 - Dec 28
This weekend
Dec 26 - Dec 28
Next weekend
Jan 2 - Jan 4
No exact matches found, but these alternatives could be just right

Recommended hotels in Lake City

Comfort Triple Room | In-room safe, desk, laptop workspace, blackout drapes
Security inn & suites

Security inn & suites

Security inn & suites
2.0 star property
Lake City
The price is NT$3,396
NT$3,803 total
includes taxes & fees
Jan 1 - 2026/1/2
Security inn & suites
Exterior
The Inn at the Crossroads

The Inn at the Crossroads

The Inn at the Crossroads
2.0 star property
Lake City
9.4 out of 10, Exceptional, (830)
"Awesome hotel stay "
United States
Jerry
The price is NT$4,217
NT$4,722 total
includes taxes & fees
Dec 27 - Dec 28
The Inn at the Crossroads
Lobby
Quality Inn & Suites Lake City

Quality Inn & Suites Lake City

Quality Inn & Suites Lake City
2.5 star property
Lake City
7.0 out of 10, Good, (166)
"Good for the weekend. "
United States
Amber
The price is NT$3,169
NT$3,550 total
includes taxes & fees
Jan 5 - 2026/1/6
Quality Inn & Suites Lake City
Property entrance
Days Inn by Wyndham Lake City

Days Inn by Wyndham Lake City

Days Inn by Wyndham Lake City
2.0 star property
Lake City
6.4 out of 10, (243)
"Overall good stay for 1 night. "
United States
April
The price is NT$3,074
NT$3,442 total
includes taxes & fees
Jan 1 - 2026/1/2
Days Inn by Wyndham Lake City
Lobby
Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area
2.5 star property
Florence
9.2 out of 10, Wonderful, (1171)
"Great location, friendly staff. "
United States
Defelicio
The price is NT$3,072
NT$3,441 total
includes taxes & fees
Jan 11 - 2026/1/12
Comfort Inn & Suites Florence Center Area
Reception
Hampton Inn & Suites Florence Center

Hampton Inn & Suites Florence Center

Hampton Inn & Suites Florence Center
2.5 star property
Florence
9.0 out of 10, Wonderful, (826)
"My go to stay while in Fairfax. "
United States
Gregory
The price is NT$3,068
NT$3,436 total
includes taxes & fees
Jan 25 - 2026/1/26
Hampton Inn & Suites Florence Center
Premium bedding, in-room safe, desk, iron/ironing board
Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center
2.5 star property
Florence
7.8 out of 10, Good, (1256)
"Room was spotless and the staff was friendly..."
United States
Randy
The price is NT$2,347
NT$2,628 total
includes taxes & fees
Jan 25 - 2026/1/26
Quality Inn & Suites Florence Civic Center
The Paris Room | Memory foam beds, individually decorated, individually furnished
Bella's Boutique Hotel

Bella's Boutique Hotel

Bella's Boutique Hotel
2.0 star property
Hemingway
6.2 out of 10, (13)
"Quaint and cozy, convenient for visiting family. The staff and owner were very welcoming and generous. "
United States
James
The price is NT$2,044
NT$3,113 total
includes taxes & fees
Dec 27 - Dec 28
Bella's Boutique Hotel
Front of property
Affordable Suites Florence

Affordable Suites Florence

Affordable Suites Florence
2.5 star property
Florence
9.2 out of 10, Wonderful, (122)
"Was clean and the staff is friendly."
United States
Marilyn
Affordable Suites Florence
View from property
Fairfield Inn & Suites by Marriott Florence I-20

Fairfield Inn & Suites by Marriott Florence I-20

Fairfield Inn & Suites by Marriott Florence I-20
2.5 star property
Florence
9.0 out of 10, Wonderful, (559)
"Clean room, professional and courteous staff. "
United States
Felicia
The price is NT$3,448
NT$3,861 total
includes taxes & fees
Jan 7 - 2026/1/8
Fairfield Inn & Suites by Marriott Florence I-20
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Lake City Hotel Reviews

The Inn at the Crossroads

The Inn at the Crossroads

10/10 Excellent
"This property is simply beautiful. It is in a great convenient location and very close to Lane, SC. The room was spacious, clean, and we enjoyed the welcome gift they provided. They provided a continental breakfast each day and we had a great experience at the Bistro Bar which is onsite. We will definitely book this hotel again....We are coming back in January!!!!!"
Rosalind 1-night trip
Posted 8 days ago
The Inn at the Crossroads

Frequently asked questions

What's there to see and do in Lake City?
The lakefront and restaurants are just some of the things to enjoy while you're in the area. Lions Park, The Country Club at Lake City, and Moore Farms Botanical Garden are some of the local sights worth visiting. You might also like to explore more of the area and take in additional sights like Greenwood Baseball Park and Playground, Lynches River State Park, and Woods Bay State Park while you're here.
What kind of weather should I plan for when I travel to Lake City?
Understanding the weather in Lake City is important when you plan your trip. The hottest months are usually July and August with an average temp of 78°F, while the coldest months are January and February with an average of 51°F. Average annual precipitation for Lake City is 53 inches.
What's the best way to get to my boutique hotel in Lake City?
You have a few options for transportation to and around Lake City. The closest major airport is Florence, SC (FLO-Florence Regional), which is located 22.2 mi (35.8 km) from the heart of the city. If you'd like to explore around the area, you may want a rental car for your journey.

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