South Central Houston, TX
Houston
Visit South Central Houston
Popular places to visit
MD Anderson Cancer Center
Though MD Anderson Cancer Center might be what brings you to town, perhaps you'll have a chance to explore more of Houston while you are here.
Rice University
Enjoy the collegiate vibe when you visit Rice University, during your travels in Houston. Experience the area's lively festivals and fascinating museums.
Houston Zoo
Feed a giraffe, catch a 4-D movie or cool off in the water park at this extraordinary zoo.
University of Houston
Enjoy the collegiate vibe when you visit University of Houston, during your travels in Houston. Experience the great live music and lively festivals in this vibrant area.
Children's Museum of Houston
You can take time to visit Children's Museum of Houston during your travels to Houston. Experience the area's acclaimed art scene and great live music.
Houston Natural Science Museum
You can spend time studying the exhibits at Houston Natural Science Museum in Houston. Experience the area's great live music and acclaimed theater scene.
South Central Houston Hotel Deals
Hotel Zaza Houston Museum District
Great property!
Reviewed on 2026/4/2
Hilton Houston Plaza/Medical Center
InterContinental Houston by IHG
Everyone is always friendly as usual!
Reviewed on 2026/3/27
The Westin Houston Medical Center/Museum District
The hotel staff made the stay completely wonderful, they also have a shuttle service to and from the Medical Center, which was fantastic. Every thing about the experience was great
Reviewed on 2026/4/4
Americas Best Value Inn Medical Center Downtown
yes
Reviewed on 2026/4/4
DoubleTree by Hilton Houston Medical Center Hotel & Suites
Everyone is so nice, kind and supportive. We have the room with kitchen and living space and it is worth the extra money for a long stay. The breakfast was average, not quite what I expected
Reviewed on 2026/4/4
Other neighborhoods around South Central Houston
Greater Third Ward
While you're in Greater Third Ward, take in top sights like Barbara Jordan & Mickey Leland Archives or Fertitta Center, and hop on the metro to see more the city at Elgin/Third Ward Station or TSU/UH Athletics District Station.
Midtown
Characterized by a vibrant nightlife and young residents, this central Houston neighborhood boasts Ensemble Theatre, the largest African-American theater company in the US, and various parks like Midtown Park and Elizabeth Baldwin Park. Easily accessible via METRORail Red Line.
East Downtown Houston
Get to know East Downtown Houston and its many features like its restaurants and live music. You might want to explore sights like Shell Energy Stadium and Giant Beatles Statues, and you can jump on the metro at Leeland/Third Ward Station or EaDo/Stadium Station to get around the city.
Museum District
Known for its ample dining options and fascinating museums, there's plenty to explore in Museum District. You can visit top attractions like Children's Museum of Houston and Houston Natural Science Museum, and jump on the metro at Museum District Station or Hermann Park/Rice U Station to see more of the city.
Houston Central Business District
If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more the city at Bell Station or Downtown Transit Center Station.
Downtown Houston
Largest central business district in Texas, this area boasts major league sports venues, a vibrant Theater District, and shopping options like GreenStreet. Easily navigate with public transportation options like METRORail and bus lines.
