The Best Business Hotels in Hannibal, MO from NT$1,952 in 2026

A river with a bridge, a town, and a forested hillside.

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Our top choices for Hannibal business-friendly hotels

Desk, iron/ironing board, WiFi (surcharge), bed sheets

Indoor pool, seasonal outdoor pool, pool umbrellas, sun loungers

1. Best Western On The River

Hannibal

Raymond

NT$3,500

NT$4,038 total

includes taxes & fees

Sep 20 - Sep 21

Suite, 1 King Bed with Sofa bed | Desk, iron/ironing board, cribs (free), WiFi (free)

2. Sleep Inn & Suites Hannibal West

Hannibal

Patricia

NT$3,490

NT$4,060 total

includes taxes & fees

Oct 11 - Oct 12

3. Quality Inn & Suites Hannibal West

Hannibal

Tom

NT$2,616

NT$3,044 total

includes taxes & fees

Oct 11 - Oct 12

In-room safe, desk, blackout drapes, iron/ironing board

4. Comfort Inn & Suites - Hannibal

Hannibal

Melanie

NT$2,447

NT$2,918 total

includes taxes & fees

Sep 20 - Sep 21

5. Baymont by Wyndham Hannibal

Hannibal

brian

NT$1,681

NT$1,952 total

includes taxes & fees

Sep 22 - Sep 23

6. Stoney Creek Inn Quincy

Quincy

Kent

NT$3,325

NT$3,790 total

includes taxes & fees

Sep 27 - Sep 28

Studio Suite, 1 Queen Bed, Accessible, Non Smoking (Mobility Accessible) | Desk, blackout drapes, WiFi (free), bed sheets

7. Microtel Inn & Suites by Wyndham Quincy Downtown/River Area

Quincy

Jarrett

NT$2,177

NT$2,481 total

includes taxes & fees

Oct 4 - Oct 5

Elite Room, 1 King Bed, Kitchenette | Living area | 55-inch Smart TV with cable channels

Luxury Suite, 1 King Bed with Sofa bed, Kitchenette | Living area | 55-inch Smart TV with cable channels

8. Heritage Hotel Quincy

Quincy

Dustine

NT$2,478

NT$2,825 total

includes taxes & fees

Sep 26 - Sep 27

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Top Hannibal Hotel Reviews

Best Western On The River

10/10 Excellent

"Needs updating."

Days Inn by Wyndham Hannibal

8/10 Good

"Breakfast selection was average."

AmericInn by Wyndham Quincy

8/10 Good

"Comfortable beds and convenient location."

Stoney Creek Inn Quincy

8/10 Good

"It was clean, nice staff, and reasonably priced."

Frequently asked questions

How much do business-friendly hotels in Hannibal cost?

Business-friendly hotels in Hannibal range between NT$1,952 and NT$4,643 per night. This means you can lock in a stay with perks like conference rooms and workspaces at a price that won't stretch the work budget. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.

What are the best business-friendly hotels in Hannibal?

Select from multiple business-friendly hotels in Hannibal that have a total average guest review rating of 8.5. Holiday Inn Express And Suites Hannibal - Medical Center, an IHG Hotel is a favorite with corporate travelers. This 2.5-stars hotel comes with amenities such as a garden and individually decorated rooms. Sleep Inn & Suites is another sought-after option. It has a 2.5-stars rating and conveniences including a swimming pool and WiFi.

How many business-friendly hotels are there in Hannibal?

There are 10 business-friendly hotels in Hannibal. Whether you're searching for amenities like meeting rooms or dependable WiFi, Expedia can help you find the ideal place.

What are the best cheap business-friendly hotels in Hannibal?

Business-friendly hotels in Hannibal start from only NT$1,952 per night, so your next work trip doesn't have to cost a fortune. Holiday Inn Express And Suites Hannibal - Medical Center, an IHG Hotel is an affordable choice that features plenty of amenities, like a swimming pool and a garden. Sleep Inn & Suites is another economical stay that's favored by corporate guests. Conveniences here include a swimming pool and WiFi. When you're ready to do some sightseeing in Hannibal, add some awesome free attractions to your work trip agenda. Mark Twain Cave and Mark Twain Memorial Lighthouse are popular. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.

Are there any family-friendly hotels in Hannibal that are also business friendly?

Vacationing with the fam, and squeezing in some work, is easy at Sleep Inn & Suites. Take advantage of amenities including complimentary breakfast and laundry facilities at this favorite 2.5-stars stay in Hannibal. Also look into Best Western On The River. Get the job done and then enjoy quality time with your loved ones at this 2.5-stars option. Complimentary breakfast and laundry facilities are a couple of the conveniences available here. Hannibal has tons of family-friendly attractions to visit once you're done with work. The kids will love exploring Mark Twain Cave and Mark Twain Cave and Cameron Cave.

Why book your business-friendly hotel in Hannibal with Expedia?

At Expedia, our top task is to help you find an ideal stay at the right price. From luxurious, corporate-friendly retreats to affordable motor inns filled with conveniences, you'll have your next work trip organized in just a few clicks.

How can I find cheap business-friendly hotels in Hannibal?

Select the "business friendly" filter, located just under the "traveler experience" heading, to find cheap business-friendly hotels in Hannibal. Then refine your search by your budget and preferred hotel star rating. Basing yourself in a less popular neighborhood is another easy way to save.

What is there to do in Hannibal near my business-friendly hotel?

Hannibal has enough activities and experiences to keep you on the go for weeks, beginning with Mark Twain Cave. Mark Twain Cave and Cameron Cave, Planters Barn Theater and Bluff City Theater are other popular attractions. If your business trip gives you time to spare, Mark Twain Boyhood Home and Museum and Rockcliffe Mansion will put the finishing touches on your itinerary.

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Check availability on Hannibal Business Hotels

Our top choices for Hannibal business-friendly hotels

1. Best Western On The River

2. Sleep Inn & Suites Hannibal West

3. Quality Inn & Suites Hannibal West

4. Comfort Inn & Suites - Hannibal

5. Baymont by Wyndham Hannibal

6. Stoney Creek Inn Quincy

7. Microtel Inn & Suites by Wyndham Quincy Downtown/River Area

8. Heritage Hotel Quincy

9. Holiday Inn Quincy East by IHG

10. FairBridge Inn Express, Monroe City

Top Hannibal Hotel Reviews

Best Western On The River

Days Inn by Wyndham Hannibal

AmericInn by Wyndham Quincy

Stoney Creek Inn Quincy

Frequently asked questions

Explore a world of travel with Expedia

Find Business Hotels in Hannibal, MO

Change your mind

Treat yourself

Be picky

Check availability on Hannibal Business Hotels

Our top choices for Hannibal business-friendly hotels

1. Best Western On The River

2. Sleep Inn & Suites Hannibal West

3. Quality Inn & Suites Hannibal West

4. Comfort Inn & Suites - Hannibal

5. Baymont by Wyndham Hannibal

6. Stoney Creek Inn Quincy

7. Microtel Inn & Suites by Wyndham Quincy Downtown/River Area

8. Heritage Hotel Quincy

9. Holiday Inn Quincy East by IHG

10. FairBridge Inn Express, Monroe City

Top Hannibal Hotel Reviews

Best Western On The River

Days Inn by Wyndham Hannibal

AmericInn by Wyndham Quincy

Stoney Creek Inn Quincy

Frequently asked questions

Explore a world of travel with Expedia