Find Gay friendly Hotels in Florence, SC

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Check availability on Florence Gay friendly Hotels

Our top choices for Florence LGBT-friendly hotels

Exterior
Holiday Inn Express & Suites Latta by IHG

Holiday Inn Express & Suites Latta by IHG

Holiday Inn Express & Suites Latta by IHG
2.5 star property
Latta
9.4 out of 10, Exceptional, (532)
"Clean and beautiful, very friendly staff "
United States
claudia
The price is NT$3,494
NT$3,808 total
includes taxes & fees
Jan 4 - 2026/1/5
Holiday Inn Express & Suites Latta by IHG
Terrace/patio
Tru by Hilton Florence I-95

Tru by Hilton Florence I-95

Tru by Hilton Florence I-95
2.5 star property
Florence
8.4 out of 10, Very Good, (1005)
"Hotel was clean , friendly staff"
United States
Gabriela
The price is NT$2,845
NT$3,296 total
includes taxes & fees
Jan 5 - 2026/1/6
Tru by Hilton Florence I-95
Exterior
Hampton Inn & Suites Florence-North-I-95

Hampton Inn & Suites Florence-North-I-95

Hampton Inn & Suites Florence-North-I-95
2.5 star property
Florence
9.0 out of 10, Wonderful, (813)
"The hotel was excellent. In fact we stayed 2 different nights on our travel up and down Rt 95. Breakfast was great and hotel very clean and quiet. "
United States
Cynthia
The price is NT$3,369
NT$3,773 total
includes taxes & fees
Jan 15 - 2026/1/16
Hampton Inn & Suites Florence-North-I-95
Free daily continental breakfast
Fairfield Inn by Marriott Hartsville

Fairfield Inn by Marriott Hartsville

Fairfield Inn by Marriott Hartsville
2.5 star property
Hartsville
8.6 out of 10, Excellent, (678)
"Good for overnight stay. Breakfast was a little disappointing….not much variety and hot food was warm at best. Room was very nice. Not familiar with area but hotel is in middle of downtown. "
United States
Lon
The price is NT$2,625
NT$2,940 total
includes taxes & fees
Dec 20 - Dec 21
Fairfield Inn by Marriott Hartsville
Front of property
Best Western Inn

Best Western Inn

Best Western Inn
2.5 star property
Florence
7.6 out of 10, Good, (1002)
"Spotless room and courteous staff"
United States
Krusaundra
The price is NT$2,776
NT$3,109 total
includes taxes & fees
Dec 16 - Dec 17
Best Western Inn
Free daily buffet breakfast
Hampton Inn & Suites Hartsville

Hampton Inn & Suites Hartsville

Hampton Inn & Suites Hartsville
2.5 star property
Hartsville
9.2 out of 10, Wonderful, (479)
"Staff was very friendly and accommodating!! Rooms were very clean! "
United States
Julia
The price is NT$3,718
NT$4,164 total
includes taxes & fees
Jan 9 - 2026/1/10
Hampton Inn & Suites Hartsville
Exterior
Staybridge Suites Florence - Civic Center by IHG

Staybridge Suites Florence - Civic Center by IHG

Staybridge Suites Florence - Civic Center by IHG
3.0 star property
Florence
9.4 out of 10, Exceptional, (926)
"Friendly staff, great breakfast, beautiful ammenities!"
United States
Brandi
The price is NT$3,681
NT$4,123 total
includes taxes & fees
Jan 11 - 2026/1/12
Staybridge Suites Florence - Civic Center by IHG
View from property
Residence Inn Marriott Florence

Residence Inn Marriott Florence

Residence Inn Marriott Florence
3.0 star property
Florence
8.8 out of 10, Excellent, (478)
"Yes our stay was great big variety on breakfast clean hotel rooms nice to have a kitchen had a great day"
United States
Marialinda
The price is NT$2,970
NT$3,326 total
includes taxes & fees
Dec 25 - Dec 26
Residence Inn Marriott Florence
Desk, blackout drapes, iron/ironing board, free WiFi
SpringHill Suites by Marriott Florence

SpringHill Suites by Marriott Florence

SpringHill Suites by Marriott Florence
3.0 star property
Florence
8.6 out of 10, Excellent, (967)
"Easy check-in. Nice room. "
United States
Tim
The price is NT$3,359
NT$3,762 total
includes taxes & fees
Dec 18 - Dec 19
SpringHill Suites by Marriott Florence
Exterior
TownePlace Suites by Marriott Florence

TownePlace Suites by Marriott Florence

TownePlace Suites by Marriott Florence
3.0 star property
Florence
9.0 out of 10, Wonderful, (702)
"Good stay, great staff"
United States
James
The price is NT$3,094
NT$3,466 total
includes taxes & fees
Dec 21 - Dec 22
TownePlace Suites by Marriott Florence
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Florence Hotel Reviews

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Frequently asked questions

Searching for a gay-friendly accommodation in Florence?
Whether you are traveling with your partner or flying solo, you'll find gay-friendly hotels in Florence on our website. Staying in this welcoming area will give you access to its shops and restaurants.
What is the favorite LGBTQ-friendly place to stay in Florence?
TownePlace Suites by Marriott Florence is a top LGBTQ-friendly hotel that features free breakfast and free parking. Tru by Hilton Florence I-95 and Courtyard by Marriott Florence are two other good options for your stay.
How many gay-friendly hotels will I find in Florence?
There are currently 18 LGBTQ-friendly places to stay in Florence.
What should I see while I'm in Florence?
During your vacation, get out and discover all that Florence has to offer. You and your traveling companions may want to visit Florence Museum, Florence National Cemetery, and Dr. Eddie Floyd Tennis Center. While you're here, create some great memories of your trip with stops at Magnolia Mall, Florence Civic Center, and Palmetto Shores Lake.
What is a gay-friendly hotel in Florence?
LGBTQ-friendly hotels are places where lesbian, gay, bisexual, and transgender travelers are proudly welcomed. We have worked with the International Gay and Lesbian Travel Association (IGLTA) to compile a selection of gay-friendly hotels worldwide. In Florence, hotels affiliated with IGLTA prioritize a diverse environment in which guests are welcomed, respected, and not obliged to declare or hide their sexual orientation.
What can I expect from a gay-friendly hotel in Florence?
Take a vacation from the ordinary; stay at a gay-friendly hotel in Florence, and you won't have to hide or your sexuality or your gender identity when you check-in. Some of Expedia's LGBTQ-friendly hotels go the extra mile and offer community-specific packages, exclusive tours, and opportunities for social interaction.