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Our top choices for El Santuario hotels

MONTANA ECO HOTEL

MONTANA ECO HOTEL
2.0 star property
El Santuario
  • cleanliness
    Sustainable farm stay near El Santuario offers eco-friendly accommodations with mountain views.
The price is NT$4,563
NT$4,563 total
Feb 5 - Feb 6
MONTANA ECO HOTEL

Hotel Bossanova

Hotel Bossanova
3.0 star property
Rionegro
9.2 out of 10, Wonderful, (5 reviews)
"Great staff. Location. "
United States
Pedro
The price is NT$1,298
NT$1,298 total
Jan 29 - Jan 30
Hotel Bossanova

Hotel Zona A

Hotel Zona A
3.0 star property
El Poblado
9.0 out of 10, Wonderful, (186 reviews)
"The staff very friendly!! Everything clean. It was so close to everything I felt very safe. Excellent service "
United States
Marcia
Hotel Zona A

The Host Medellin Only Adults

The Host Medellin Only Adults
3.0 star property
El Poblado
9.8 out of 10, Exceptional, (20 reviews)
  • cleanliness
    Sophisticated adults-only retreat in Medellín, steps from vibrant Poblado Park.
"Great ambience and room, excellent breakfast "
United States
Shailendra
The price is NT$6,533
NT$6,533 total
Jan 30 - Jan 31
The Host Medellin Only Adults

City Express Plus by Marriott Medellin Colombia

City Express Plus by Marriott Medellin Colombia
3.5 star property
El Poblado
8.6 out of 10, Excellent, (388 reviews)
  • cleanliness
    Stay steps from Oviedo Shopping Center with free breakfast and parking.
"I will definitely be back to this place"
United States
Jessica
The price is NT$3,218
NT$3,218 total
Feb 7 - Feb 8
City Express Plus by Marriott Medellin Colombia

NEW STAR CENTER

NEW STAR CENTER
3.0 star property
Rionegro
8.6 out of 10, Excellent, (39 reviews)
  • cleanliness
    Stylish hotel near Rionegro attractions with convenient airport proximity.
"Great staff"
United States
Stephanie
The price is NT$2,466
NT$2,466 total
Jan 24 - Jan 25
NEW STAR CENTER

Hotel Helene

Hotel Helene
3.5 star property
El Poblado
8.4 out of 10, Very Good, (198 reviews)
  • cleanliness
    Stay a 5-minute walk from Lleras Park in a prime Medellín location.
"Staff was very attentive and friendly."
United States
Elizabeth
The price is NT$1,511
NT$1,511 total
Feb 22 - Feb 23
Hotel Helene

LIN Boutique Hotel by HOUSY HOST

LIN Boutique Hotel by HOUSY HOST
3.0 star property
El Poblado
9.0 out of 10, Wonderful, (150 reviews)
  • cleanliness
    Experience a boutique retreat steps from vibrant Lleras Park in Medellín.
"Amazing stay"
United States
Waldemar
The price is NT$2,402
NT$2,402 total
Feb 10 - Feb 11
LIN Boutique Hotel by HOUSY HOST

23 Living

23 Living
3.0 star property
El Poblado
9.4 out of 10, Exceptional, (16 reviews)
  • cleanliness
    Stylish Medellín hotel with rooftop bars steps from vibrant Lleras Park.
"Everything and everyone is awesome "
United States
Deivid
The price is NT$3,871
NT$3,871 total
Feb 15 - Feb 16
23 Living

MG Hotels & Suites

MG Hotels & Suites
3.5 star property
Rionegro
8.8 out of 10, Excellent, (215 reviews)
  • cleanliness
    Take in the sun at Rionegro's sauna-equipped haven, steps from popular malls.
"The room was spotless, my family felt very safe. The front office staff was very accommodating, friendly and helpful with directions to the nearest mall. I would have given it 5 stars but the pool was being worked on and my granddaughters wanted to swim. Other than that, everything was well kept."
United States
Xochitl
The price is NT$5,587
NT$5,587 total
Jan 25 - Jan 26
MG Hotels & Suites

The Somos Central Hotel Poblado

The Somos Central Hotel Poblado
4.0 star property
El Poblado
9.0 out of 10, Wonderful, (263 reviews)
  • cleanliness
    Explore this hip hotel just steps from parks in Medellín's vibrant El Poblado district.
"The staff was wonderful and the location was great"
United States
Eve
The price is NT$2,096
NT$2,096 total
Feb 4 - Feb 5
The Somos Central Hotel Poblado

La Campana Hotel Boutique

La Campana Hotel Boutique
3.0 star property
El Poblado
9.0 out of 10, Wonderful, (214 reviews)
  • cleanliness
    Colonial retreat near Poblado and Lleras Park, perfect for exploring Medellín.
"Our room was a great space to unwind and relax - large and comfortable. The staff was excellent - very helpful and accommodating. It’s a beautiful hotel and walkable to restaurants."
United States
Elisabeth
La Campana Hotel Boutique

Hotel Rulay Medellin

Hotel Rulay Medellin
4.0 star property
El Poblado
8.6 out of 10, Excellent, (4 reviews)
"new, clean, good breakfast, close to everything"
United States
Oscar
The price is NT$2,803
NT$3,027 total
Jan 31 - Feb 1
Hotel Rulay Medellin

Casa Rose Hotel

Casa Rose Hotel
3.5 star property
El Carmen de Viboral
9.6 out of 10, Exceptional, (55 reviews)
  • cleanliness
    Tranquil retreat in El Carmen de Viboral with deep-tissue massages and dining.
"Friendly staff, clean room, excellent location."
United States
Daniel
The price is NT$2,502
NT$2,502 total
Jan 31 - Feb 1
Casa Rose Hotel

Hotel Madeiro

Hotel Madeiro
3.0 star property
El Poblado
8.4 out of 10, Very Good, (249 reviews)
  • cleanliness
    Unwind at a spa sanctuary near vibrant Lleras Park in Medellín's El Poblado district.
"Incredible location and my time at Madeiro was very nice. I recommend everyone to stay here. "
United States
David
Hotel Madeiro

Nomada Hotel Origen

Nomada Hotel Origen
3.0 star property
El Poblado
9.4 out of 10, Exceptional, (106 reviews)
  • cleanliness
    Enjoy the hip El Poblado neighborhood with cafes, parks, and vibrant nightlife.
"Lovely place, great service, awesome food!"
United States
Alejandro
The price is NT$2,595
NT$2,595 total
Jan 29 - Jan 30
Nomada Hotel Origen

Hotel Poblado Alejandria

Hotel Poblado Alejandria
3.5 star property
El Poblado
9.0 out of 10, Wonderful, (488 reviews)
  • cleanliness
    Rooftop views await in El Poblado, steps from premier shopping centers.
"Friendly staff, excellent breakfast and clean room "
United States
Betty
The price is NT$2,799
NT$2,799 total
Jan 29 - Jan 30
Hotel Poblado Alejandria

Sites Hotel

Sites Hotel
4.0 star property
El Poblado
9.2 out of 10, Wonderful, (1,121 reviews)
  • cleanliness
    Stay in a modern, fully-equipped apartment near Medellín's Poblado neighborhood.
"Clean room, wonderful staff and great location!!!"
United States
Marleny
The price is NT$2,995
NT$2,995 total
Feb 8 - Feb 9
Sites Hotel

La Quinta by Wyndham Medellin

La Quinta by Wyndham Medellin
3.5 star property
San Diego
8.8 out of 10, Excellent, (1,001 reviews)
  • cleanliness
    Unwind in Medellín with poolside refreshments and convenient city access.
"Clean room, good food, nice personal! "
United States
Rubiela
The price is NT$2,474
NT$2,474 total
Feb 1 - Feb 2
La Quinta by Wyndham Medellin

Hampton by Hilton Medellin

Hampton by Hilton Medellin
3.5 star property
El Poblado
8.8 out of 10, Excellent, (499 reviews)
"Exellent food and Staff"
United States
Armando
The price is NT$3,021
NT$3,021 total
Feb 8 - Feb 9
Hampton by Hilton Medellin
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about El Santuario

Head to San Nicolás Mall and Rock of Guatapé—just two of the sights around El Santuario.

El Santuario, Antioquia, Colombia. June 28, 2025. Panoramic drone view of the town's main church.

Top El Santuario Hotel Reviews

More cheap stays in El Santuario

Frequently asked questions

Where is the best place to stay in El Santuario?
Located 21.6 mi (34.7 km) from the heart of El Santuario, Calle Flora Hotel by Jalo is a top choice for your stay based on our traveler data. Other good choices for your visit to the area are Heiss Hotel By Jalo and Dann Carlton Medellin Hotel. See all available top hotels, or vacation rentals in El Santuario.
What's the top vacation rental that El Santuario has to offer?
EP Casa Uribe Architecture Art & Nature: This vacation home rental outside of El Santuario is located in a shopping district and has an outdoor pool, a balcony, and laundry facilities to put you at ease in your new surroundings. Kitchen amenities include a dishwasher, a fridge, and a stovetop. See all vacation rentals in El Santuario.
If I need to cancel my hotel reservation in El Santuario, will I receive a refund?
Yes, most room reservations are fully refundable if cancelled before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your arrival date. If you booked a non-refundable reservation, you might still have the option to cancel and get a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in El Santuario.
Where can I learn more about changing or cancelling my trip to El Santuario?
To access more information about updating your trip to El Santuario or cancelling it, click here.
What's it like staying in El Santuario?
Visitors are sure to enjoy all that El Santuario has to offer. In El Santuario, there are 2 hotels and other accommodations to choose from. Find out more about El Santuario.
What are the top places to visit in El Santuario?
Places to visit in the wider area include San Nicolás Mall, Rock of Guatapé, and Parque Comfama. You'll also find Llanogrande Mall and Peñol-Guatapé Reservoir in the area. Check out what more to see and do in Expedia's El Santuario guide.
What's the seasonal weather like in El Santuario?
The hottest months are usually August and September with an average temp of 63°F, while the coldest months are January and July with an average of 63°F. The rainiest months in El Santuario are April, May, October, and November, with each month seeing an average of 17 inches of rainfall.