Find Gay friendly Hotels in Downtown South San Francisco, CA

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Check availability on Downtown South San Francisco Gay friendly Hotels

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Our top choices for Downtown South San Francisco LGBT-friendly hotels

La Quinta Inn & Suites by Wyndham San Francisco Airport N

La Quinta Inn & Suites by Wyndham San Francisco Airport N
3.0 star property
Downtown South San Francisco
8.0 out of 10, Very Good, (2006)
"Clean room, staff were friendly, breakfast was good, parking was good, overall we're satisfied!"
Canada
Edna
The price is NT$3,180
NT$3,735 total
includes taxes & fees
Jan 1 - 2026/1/2
La Quinta Inn & Suites by Wyndham San Francisco Airport N

Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf
4.0 star property
Fisherman's Wharf
9.0 out of 10, Wonderful, (7251)
"Great place to stay!"
United States
Isaiah
The price is NT$3,133
NT$4,983 total
includes taxes & fees
Jan 5 - 2026/1/6
Hotel Riu Plaza Fisherman's Wharf

The Westin San Francisco Airport

The Westin San Francisco Airport
4.0 star property
Millbrae
8.8 out of 10, Excellent, (2018)
"Comfortable room, welcome glass of wine, easy shuttle to and from airport, friendly staff."
United States
Carole
The price is NT$3,235
NT$4,639 total
includes taxes & fees
Dec 31 - 2026/1/1
The Westin San Francisco Airport

Aloft San Francisco Airport

Aloft San Francisco Airport
3.0 star property
Millbrae
9.0 out of 10, Wonderful, (2249)
"Spotless — not fancy but clean open and comfortable !!! Great airport hotel!!!!"
United States
Michael
The price is NT$3,264
NT$3,752 total
includes taxes & fees
Dec 30 - Dec 31
Aloft San Francisco Airport

Club Quarters Hotel in San Francisco

Club Quarters Hotel in San Francisco
4.0 star property
Downtown San Francisco
8.8 out of 10, Excellent, (2834)
"Clean room, friendly staff and good location"
United States
Jose Eduardo
The price is NT$3,181
NT$3,744 total
includes taxes & fees
Jan 3 - 2026/1/4
Club Quarters Hotel in San Francisco

Hotel Caza Fisherman's Wharf

Hotel Caza Fisherman's Wharf
4.0 star property
Fisherman's Wharf
9.0 out of 10, Wonderful, (3836)
"Excellent stay and great location! "
United States
CHRISTINE
The price is NT$3,981
NT$6,128 total
includes taxes & fees
Jan 4 - 2026/1/5
Hotel Caza Fisherman's Wharf

Hilton San Francisco Financial District

Hilton San Francisco Financial District
4.0 star property
Downtown San Francisco
8.8 out of 10, Excellent, (2201)
"Great hotel "
United States
Tanya
The price is NT$3,583
NT$4,217 total
includes taxes & fees
Jan 5 - 2026/1/6
Hilton San Francisco Financial District

Handlery Union Square Hotel

Handlery Union Square Hotel
3.5 star property
Union Square
8.8 out of 10, Excellent, (2795)
"Clean hotel, great location, kind staff! "
United States
Felix
The price is NT$3,988
NT$4,693 total
includes taxes & fees
Dec 30 - Dec 31
Handlery Union Square Hotel

Holiday Inn Express and Suites Fisherman's Wharf by IHG

Holiday Inn Express and Suites Fisherman's Wharf by IHG
3.0 star property
Fisherman's Wharf
9.0 out of 10, Wonderful, (2240)
"Awesome place to stay"
United States
Mark Anthony
The price is NT$3,741
NT$5,346 total
includes taxes & fees
Jan 4 - 2026/1/5
Holiday Inn Express and Suites Fisherman's Wharf by IHG

Hilton San Francisco Airport Bayfront

Hilton San Francisco Airport Bayfront
4.0 star property
Bayfront
8.6 out of 10, Excellent, (2784)
"Breakfast was very good, many options to choose. "
United States
Hourn
The price is NT$3,297
NT$3,748 total
includes taxes & fees
Jan 2 - 2026/1/3
Hilton San Francisco Airport Bayfront
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Downtown South San Francisco Hotel Reviews

Frequently asked questions

Searching for an LGBTQ-friendly hotel in Downtown South San Francisco?
Consider this your open invitation to pack your bags and find Downtown South San Francisco hotels that are members of the International Gay & Lesbian Travel Association on our website. Discover the people, places, and traditions found only in Downtown South San Francisco.
What is the favorite LGBTQ-friendly accommodation in Downtown South San Francisco?
La Quinta Inn & Suites by Wyndham San Francisco Airport N is a top LGBTQ-friendly hotel that features free breakfast and free WiFi.
What is there to see in Downtown South San Francisco?
During your vacation, get out and discover all that Downtown South San Francisco is known for. You and your traveling companions may want to visit San Francisco Bay, Oracle Park, and Pier 39.
What is an LGBTQ-friendly hotel in Downtown South San Francisco?
LGBTQ-friendly hotels are places where lesbian, gay, bisexual, and transgender travelers are proudly welcomed. You'll find a selection of LGBTQ-friendly accommodations on our site. In Downtown South San Francisco, these hotels prioritize a diverse environment in which guests are welcomed, respected, and not obliged to declare or hide their sexual orientation.
What can I expect from an LGBTQ-friendly Downtown South San Francisco hotel?
Take a vacation from the ordinary; stay at an LGBTQ-friendly hotel in Downtown South San Francisco, and the staff will help you explore the local gay scene and the LGBTQ+ culture. Some of Expedia's LGBTQ-friendly hotels go the extra mile and offer community-specific packages, exclusive tours, and opportunities for social interaction.

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