Find Luxury Hotels in Downtown Frederick, MD
Change your mind
Book hotels with free cancellation
Be picky
Search almost a million properties worldwide
Check availability on Downtown Frederick Luxury Hotels
Top Downtown Frederick Luxury Hotels
Top Downtown Frederick Hotel Reviews
Motel 6 Frederick, MD - Fort Detrick
10/10 Excellent
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Hotels near popular Frederick Attractions
- Hotels near National Museum of Civil War Medicine
- Hotels near Historical Society of Frederick County
- Hotels near Evangelical Lutheran Church
- Hotels near Harpers Ferry National Historical Park
- Hotels near Maryland SoccerPlex
- Hotels near Shenandoah River
- Hotels near Antietam National Battlefield
- Hotels near Francis Scott Key Mall
- Hotels near Potomac River
- Hotels near Mount St. Mary's University
Downtown Frederick Hotels by Star Rating
Explore more hotels
- Hampton Inn & Suites Frederick-Fort Detrick
- Super 8 by Wyndham Frederick
- Extended Stay America Suites Washington DC Germantown Milest
- Motel 6 Frederick, MD - Fort Detrick
- Fairfield Inn & Suites by Marriott Frederick
- Holiday Inn Express & Suites Brunswick - Harpers Ferry Area by IHG
- Best Western Historic Frederick
- Home2 Suites by Hilton Frederick
- Hampton Inn Frederick
- Clarion Inn Frederick Event Center
- Fairfield Inn & Suites Germantown Gaithersburg
- Courtyard by Marriott Frederick
- Econo Lodge Frederick I-70
- Extended Stay America Suites Frederick Westview Dr
- The Hillside Hotel
- Antietam Overlook Farm
- Super 8 by Wyndham Thurmont
- TownePlace Suites by Marriott Frederick
- Travelodge by Wyndham Brunswick near Frederick
- WoodSpring Suites Frederick I-70
More ways to book
Expedia's Latest Trends
Hotels
Flights
- China Eastern Airlines
- Flights from Taoyuan City (TPE) to Anchorage (ANC)
- Flights from Taoyuan City (TPE) to Ipoh (IPH)
- Flights from Singapore (SIN) to Christchurch (CHC)
- Flights from Los Angeles (LAX) to Guadalajara (GDL)
- Flights from Taoyuan City (TPE) to Yundum (BJL)
- Flights from Taoyuan City (TPE) to Windsor Locks (BDL)
- Lufthansa
- Flights from New York (JFK) to Seattle (SEA)
- Flights from Auburn (AUO) to Manado (MDC)
Packages