The Best Business Hotels in Big Pine Key, FL from NT$2,807 in 2026

A calm river with boats, lush greenery, and a clear blue sky.

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Our top choices for Big Pine Key business-friendly hotels

Three colorful drinks on a table with a thatched roof and outdoor seating.

A pool area with lounge chairs, a thatched-roof structure, and a view of the ocean.

A bar area with wicker chairs and a thatched roof, overlooking a body of water with boats.

A modern kitchen with a central island, various appliances, and hanging pendant lights.

1. Hampton Inn Marathon - Florida Keys

Marathon

Linda

NT$4,445

NT$5,001 total

includes taxes & fees

Oct 25 - Oct 26

A bar area with a long counter, bar stools, and a view of the water.

A waterfront property with a large building, a smaller structure with a thatched roof, and several boats docked.

A balcony with a view of a body of water, a pool, and outdoor seating.

A balcony with a view of the ocean, a round table, and two chairs.

2. Fairfield Inn & Suites by Marriott Marathon Florida Keys

Marathon

Andrew

NT$4,348

NT$4,892 total

includes taxes & fees

Oct 29 - Oct 30

An aerial view of a resort with a central pool, multiple buildings, and a beach area with sun loungers.

An aerial view of a resort with a large building, a beach, and a pier in the background.

A beach scene with two white chairs, a hammock, and palm trees.

A beach with white chairs and kayaks, palm trees, and a clear view of the ocean.

3. Isla Bella Beach Resort & Spa

Marathon

Clinton

NT$6,683

NT$9,459 total

includes taxes & fees

Oct 25 - Oct 26

A bar area with a long counter, multiple stools, and a view of the marina with boats.

A pool area with lounge chairs and umbrellas, surrounded by palm trees and a large tree in the background.

A fire pit with two Adirondack chairs and a table with drinks, set on a grassy area with a view of a building and palm trees in the background.

A modern hotel room with a sofa, a small table, a lamp, and a bed.

4. Faro Blanco Resort Marathon Florida Keys, Curio by Hilton

Marathon

Rick

NT$4,778

NT$6,600 total

includes taxes & fees

Nov 15 - Nov 16

Two hammocks on a sandy beach with a clear blue sky and turquoise water.

An aerial view of a coastal resort with a marina, palm trees, and a large building complex.

A clear blue pool with white lounge chairs and palm trees, overlooking a calm sea.

A poolside area with lounge chairs, blue umbrellas, and a fire pit.

5. Courtyard by Marriott Faro Blanco Resort, Marathon Florida Keys

Marathon

amy

NT$4,125

NT$5,775 total

includes taxes & fees

Oct 29 - Oct 30

A nighttime pool area with a clear view of the pool, surrounding palm trees, and a building with a sign.

A hotel entrance with a covered walkway, palm trees, and a clear blue sky.

A buffet setup with various food items and condiments.

A table with breakfast items, a basket, and a view of a parking lot and buildings.

6. Skipjack Resort & Marina

Marathon

Justin

NT$4,932

NT$6,862 total

includes taxes & fees

Oct 25 - Oct 26

A building with a white exterior, purple doors, and a small patio area with chairs and a table.

A hotel room with two beds, a desk, a chair, a TV, and a window with curtains.

A garden with a stone border, palm trees, and various plants.

A compact kitchen with wooden cabinets, a microwave, and a refrigerator. There is a dining area with wicker chairs and a small table.

7. Siesta Motel

Marathon

Jairo

NT$2,495

NT$2,807 total

includes taxes & fees

Nov 8 - Nov 9

A swimming pool surrounded by palm trees and lounge chairs.

A spacious living room with a wooden coffee table, a striped sofa, and a television on a wooden cabinet.

A beach scene with a wooden deck, palm trees, and a gazebo-like structure.

A wooden deck with blue chairs overlooking a beach with palm trees and the ocean.

8. Tranquility Bay Beachfront Hotel and Resort

Marathon

Stuart

NT$6,744

NT$9,677 total

includes taxes & fees

Nov 15 - Nov 16

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Top Big Pine Key Hotel Reviews

Fairfield Inn & Suites by Marriott Marathon Florida Keys

10/10 Excellent

"Just wow! Everything was amazing."

Parmer's Resort

10/10 Excellent

"All Aspects"

Coconut Cay Resort & Marina

10/10 Excellent

"We stayed here for one night during our visit to Marathon in the Florida Keys. The location was nice enough and convenient for exploring the area. Our room was situated at the front of the property, so there was quite a lot of road and car park noise, although this was somewhat expected given the location. It did feel as though the front window was open, despite being closed, as it did very little to block out the outside noise. On the positive side, the room was incredibly spacious, with a lovely large TV and a super comfortable bed. The shower was great, and the amenities provided were good. Ice and drinks were also available from reception, which was handy. The reception staff were exceptionally friendly and welcoming. The air conditioning worked overtime but didn’t seem to cool the room particularly well and was rather noisy itself. However, this was more of a minor observation than a complaint. The only real disappointment was the cleanliness of the floor. After showering, the floor became slightly wet, and walking around barefoot left the bottoms of my feet noticeably dirty, which was a shame. Overall, a perfectly reasonable place to stay for a night in Marathon. A few minor improvements would make a difference, but we had a comfortable stay, and the friendly staff were certainly a highlight."

Courtyard by Marriott Faro Blanco Resort, Marathon Florida Keys

10/10 Excellent

"Beautiful infinity pool. Very helpful front desk staff at check in and check out. Thank you for a great stay!"

Tranquility Bay Beachfront Hotel and Resort

10/10 Excellent

"Nice layout"

Looe Key Reef Resort

8/10 Good

"They had a nice pool you could park your boat in the channel they also had a very nice tiki bar and grill it was an ok place to stay but parking sucked"

Frequently asked questions

Why book your business-friendly hotel in Big Pine Key with Expedia?

At Expedia, our top task is to help you choose a suitable stay at the right price. From deluxe, corporate-friendly escapes to affordable hotels filled with all the amenities you need, you'll have your next work trip planned in a couple of clicks.

How can I find cheap business-friendly hotels in Big Pine Key?

Expedia can help you narrow your search for cheap business-friendly hotels in Big Pine Key. Simply go to the "traveler experience" filter and click on "business friendly." This will show you stays with amenities designed to help you work effectively and comfortably, like free WiFi and included breakfast. You can also choose your budget and hotel star rating to keep costs down.

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Book Business Hotels in Big Pine Key on Expedia.com

Find Business Hotels in Big Pine Key, FL

Change your mind

Treat yourself

Be picky

Check availability on Big Pine Key Business Hotels

Our top choices for Big Pine Key business-friendly hotels

1. Hampton Inn Marathon - Florida Keys

2. Fairfield Inn & Suites by Marriott Marathon Florida Keys

3. Isla Bella Beach Resort & Spa

4. Faro Blanco Resort Marathon Florida Keys, Curio by Hilton

5. Courtyard by Marriott Faro Blanco Resort, Marathon Florida Keys

6. Skipjack Resort & Marina

7. Siesta Motel

8. Tranquility Bay Beachfront Hotel and Resort

Top Big Pine Key Hotel Reviews

Fairfield Inn & Suites by Marriott Marathon Florida Keys

Parmer's Resort

Coconut Cay Resort & Marina

Courtyard by Marriott Faro Blanco Resort, Marathon Florida Keys

Tranquility Bay Beachfront Hotel and Resort

Looe Key Reef Resort

Frequently asked questions

Explore a world of travel with Expedia