Photo by Donna Flores
Central Southwest 5 Stars Hotels
Change your mind
Book hotels with free cancellation
Be picky
Search almost a million properties worldwide
Check availability on Central Southwest 5 Star Hotels
Compare Central Southwest 5 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.
Our top choices for Central Southwest 5-star hotels

The Post Oak Hotel at Uptown Houston
The Post Oak Hotel at Uptown Houston
9.6 out of 10, Exceptional, (800)
The price is NT$16,626
NT$19,452 total
includes taxes & fees
Sep 10 - Sep 11

Four Seasons Hotel Houston
Four Seasons Hotel Houston
9.2 out of 10, Wonderful, (1001)
The price is NT$15,755
NT$18,585 total
includes taxes & fees
Aug 31 - Sep 1

JW Marriott Houston Downtown
JW Marriott Houston Downtown
9.0 out of 10, Wonderful, (1002)
The price is NT$6,339
NT$7,631 total
includes taxes & fees
Sep 5 - Sep 6

ACP Hotel Houston Westchase, MOD Collection by Sonesta
ACP Hotel Houston Westchase, MOD Collection by Sonesta
8.0 out of 10, Very Good, (1005)
The price is NT$2,063
NT$2,414 total
includes taxes & fees
Sep 1 - Sep 2

The St. Regis Houston
The St. Regis Houston
9.2 out of 10, Wonderful, (396)
The price is NT$12,350
NT$14,729 total
includes taxes & fees
Sep 6 - Sep 7

La Colombe d'Or Hotel
La Colombe d'Or Hotel
9.4 out of 10, Exceptional, (129)
The price is NT$13,756
NT$16,094 total
includes taxes & fees
Sep 3 - Sep 4

7550 Kirby Dr
7550 Kirby Dr
8.2 out of 10, Very Good, (45)

TUSCAN VILLA
TUSCAN VILLA
2.0 out of 10, (3)
Save an average of 15% on thousands of hotels when you're signed in
Explore similar 4-star hotels
Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Central Southwest.

Hilton Houston Plaza/Medical Center
6633 Travis St, Houston, TX
The price is NT$2,586 per night from Sep 4 to Sep 5
NT$2,586
NT$3,061 total
Sep 4 - Sep 5
includes taxes & fees
8.2/10 Very Good! (1,540 reviews)
Still don't see what you're looking for?
See all properties in Central Southwest.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Central Southwest Hotel Reviews
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Central Southwest Hotels by Star Rating
Hotels in Central Southwest Neighborhoods
Stay near popular Central Southwest attractions
- Hotels near Aveva Stadium
- Hotels near Houston Sports Park
- Hotels near Wildcat Golf Club
- Hotels near Sculpture Park
- Hotels near NRG Stadium
- Hotels near MD Anderson Cancer Center
- Hotels near George R. Brown Convention Center
- Hotels near NASA Johnson Space Center
- Hotels near Daikin Park
- Hotels near Toyota Center
- Hotels near Rice University
- Hotels near University of Houston
- Hotels near Houston Zoo
- Hotels near Space Center Houston
- Hotels near Westheimer Road
- Hotels near Memorial City Mall
- Hotels near Downtown Aquarium
- Hotels near CityCentre
- Hotels near NRG Park
- Hotels near Smart Financial Centre at Sugar Land
Explore more hotels
- The Royal Sonesta Houston Galleria
- Hyatt Place Houston Downtown
- Hilton Americas-Houston
- Heritage Place Houston Brookhollow
- The Chifley Houston, Tapestry Collection by Hilton
- The Westin Galleria Houston
- Hyatt Place Houston Medical Center
- Crowne Plaza Houston Med Ctr-Galleria Area by IHG
- Omni Houston Hotel
- Marriott Marquis Houston
- Hotel Zaza Houston Museum District
- Holiday Inn Houston Intercontinental Airport by IHG
- C. Baldwin, Curio Collection by Hilton
- Hyatt Regency Houston Downtown
- Hyatt Place Houston/Sugar Land
- Aloft Houston Downtown
- SpringHill Suites Houston Medical Center/NRG Park
- The Laura Hotel, Houston Downtown, Autograph Collection
- The Moran CITYCENTRE
- Hotel Ylem
Expedia's Latest Trends
Hotels
Flights
Cars
Packages