Texas Medical Center 4 Stars Hotels

Start date: Check-in selected.
End date: Check-out
    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check availability on Texas Medical Center 4 Star Hotels

Compare Texas Medical Center 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Our top choices for Texas Medical Center 4-star hotels

Hotel Zaza Houston Museum District
1 bedroom, premium bedding, pillowtop beds, minibar

Hotel Zaza Houston Museum District

4.5 star property
9.0 out of 10, Wonderful, (1771)
"I loved this hotel. I loved the staff’s hospitality."
Hotel Zaza Houston Museum District
Club Quarters Hotel Downtown, Houston
Lobby

Club Quarters Hotel Downtown, Houston

4.0 star property
8.4 out of 10, Very Good, (3678)
"Location and prices are worth it to stay here. "
The price is NT$3,457
NT$4,045 total
includes taxes & fees
Sep 21 - Sep 22
Club Quarters Hotel Downtown, Houston
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
Exterior detail

DoubleTree by Hilton Hotel & Suites Houston by the Galleria

4.0 star property
8.2 out of 10, Very Good, (2515)
"Great stay "
The price is NT$3,519
NT$4,145 total
includes taxes & fees
Sep 28 - Sep 29
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
Hyatt Regency Houston/Galleria
Outdoor pool, open 6:00 AM to 10:00 PM, pool umbrellas, sun loungers

Hyatt Regency Houston/Galleria

4.0 star property
9.0 out of 10, Wonderful, (1053)
"It was a great stay"
The price is NT$4,808
NT$5,661 total
includes taxes & fees
Oct 2 - Oct 3
Hyatt Regency Houston/Galleria
DoubleTree by Hilton Hotel Houston - Greenway Plaza
Business center

DoubleTree by Hilton Hotel Houston - Greenway Plaza

4.0 star property
8.2 out of 10, Very Good, (1170)
"Great place!"
The price is NT$2,740
NT$3,206 total
includes taxes & fees
Sep 21 - Sep 22
DoubleTree by Hilton Hotel Houston - Greenway Plaza
The Westin Galleria Houston
Banquet hall

The Westin Galleria Houston

4.5 star property
9.0 out of 10, Wonderful, (1002)
"Nice stay"
The price is NT$6,401
NT$8,465 total
includes taxes & fees
Sep 20 - Sep 21
The Westin Galleria Houston
C. Baldwin, Curio Collection by Hilton
Lunch, dinner, brunch served; Italian cuisine

C. Baldwin, Curio Collection by Hilton

4.0 star property
8.6 out of 10, Excellent, (1004)
"Great stay looking forward to staying again!"
The price is NT$4,802
NT$6,422 total
includes taxes & fees
Sep 21 - Sep 22
C. Baldwin, Curio Collection by Hilton
The Whitehall Houston
City view from property

The Whitehall Houston

4.0 star property
8.6 out of 10, Excellent, (1717)
"great stay!"
The price is NT$4,337
NT$5,074 total
includes taxes & fees
Sep 21 - Sep 22
The Whitehall Houston
Hilton Houston Plaza/Medical Center
Sundeck

Hilton Houston Plaza/Medical Center

4.5 star property
8.4 out of 10, Very Good, (1577)
"Bed was great ..slept so well..nice and friendly staff "
The price is NT$2,691
NT$3,184 total
includes taxes & fees
Sep 14 - Sep 15
Hilton Houston Plaza/Medical Center
The Chifley Houston, Tapestry Collection by Hilton
Lobby

The Chifley Houston, Tapestry Collection by Hilton

4.0 star property
9.2 out of 10, Wonderful, (1089)
"Our stay was perfect! "
The price is NT$4,657
NT$5,449 total
includes taxes & fees
Sep 14 - Sep 15
The Chifley Houston, Tapestry Collection by Hilton
Blossom Hotel Houston
Front of property

Blossom Hotel Houston

4.0 star property
9.0 out of 10, Wonderful, (3497)
"Clean and spacious rooms Restaurant had good food Pool was nice bar was a plus Will be back again "
The price is NT$4,572
NT$5,350 total
includes taxes & fees
Oct 12 - Oct 13
Blossom Hotel Houston
The Moran CITYCENTRE
Exterior

The Moran CITYCENTRE

4.0 star property
9.0 out of 10, Wonderful, (1006)
"Would stay here again and again and again"
The Moran CITYCENTRE
The Royal Sonesta Houston Galleria
Exterior

The Royal Sonesta Houston Galleria

4.0 star property
8.4 out of 10, Very Good, (1239)
"This hotel stay was the best highly recommended "
The price is NT$3,515
NT$4,891 total
includes taxes & fees
Sep 19 - Sep 20
The Royal Sonesta Houston Galleria
Hilton Americas-Houston
Exterior

Hilton Americas-Houston

4.0 star property
9.4 out of 10, Exceptional, (1491)
"Loved the hotel location and amenities. "
The price is NT$7,078
NT$8,352 total
includes taxes & fees
Sep 20 - Sep 21
Hilton Americas-Houston
Omni Houston Hotel
Interior

Omni Houston Hotel

4.0 star property
9.0 out of 10, Wonderful, (1007)
"Enjoyed the stay "
The price is NT$5,056
NT$6,005 total
includes taxes & fees
Sep 28 - Sep 29
Omni Houston Hotel
Houston Marriott West Loop by The Galleria
Meeting facility

Houston Marriott West Loop by The Galleria

4.0 star property
8.0 out of 10, Very Good, (853)
"This is a good property and stay"
The price is NT$3,804
NT$4,524 total
includes taxes & fees
Sep 28 - Sep 29
Houston Marriott West Loop by The Galleria
Magnolia Hotel Houston, A Tribute Portfolio Hotel
View from property

Magnolia Hotel Houston, A Tribute Portfolio Hotel

4.0 star property
9.2 out of 10, Wonderful, (1136)
"Enjoyed our stay"
The price is NT$4,428
NT$5,274 total
includes taxes & fees
Sep 21 - Sep 22
Magnolia Hotel Houston, A Tribute Portfolio Hotel
Thompson Houston, by Hyatt
Lobby

Thompson Houston, by Hyatt

4.0 star property
9.2 out of 10, Wonderful, (195)
"Rooms were fantastic "
The price is NT$7,802
NT$10,420 total
includes taxes & fees
Sep 26 - Sep 27
Thompson Houston, by Hyatt
Marriott Marquis Houston
2 outdoor pools, open 6:00 AM to 10:00 PM, cabanas (surcharge)

Marriott Marquis Houston

4.0 star property
8.8 out of 10, Excellent, (1013)
"It's a very beautiful hotel, the lazy river is amazing the kids loved it! And the Views gorgeous!"
The price is NT$7,965
NT$10,319 total
includes taxes & fees
Sep 21 - Sep 22
Marriott Marquis Houston
Hotel ZaZa Houston Memorial City
Sauna

Hotel ZaZa Houston Memorial City

4.0 star property
9.4 out of 10, Exceptional, (1003)
"Wonderful place"
Hotel ZaZa Houston Memorial City
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Texas Medical Center.
The Post Oak Hotel at Uptown Houston

The Post Oak Hotel at Uptown Houston

1600 West Loop South, Houston, TX
The price is NT$16,451 per night from Sep 28 to Sep 29
NT$16,451
NT$19,248 total
Sep 28 - Sep 29
includes taxes & fees
9.6/10 Exceptional! (811 reviews)
Still don't see what you're looking for?
See all properties in Texas Medical Center.
You can also use these popular filters to refine your search.
PoolSpaHot tubBreakfast includedWaterpark
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Texas Medical Center Hotel Reviews

DoubleTree by Hilton Hotel & Suites Houston by the Galleria

DoubleTree by Hilton Hotel & Suites Houston by the Galleria

10/10 Excellent
"The only place to stay when you’re visiting Houston. Great staff."
Michael Brown 3-night trip
Posted 18 hours ago
DoubleTree by Hilton Hotel & Suites Houston by the Galleria

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Frequently asked questions

What are the best 4-star hotels in Texas Medical Center?
Blossom Hotel Houston and DoubleTree by Hilton Houston Medical Center Hotel & Suites are two highly recommended picks situated in or near Texas Medical Center. Both have a 4-star rating and promise luxury comfort alongside an unbeatable traveler experience. Book a stay at the first and enjoy access to premium bedding and designer toiletries. The second has premium bedding and a swimming pool, among other amenities.
How much does it cost to stay in a 4-star hotel in Texas Medical Center?
With Expedia's handy search filters, scoring a top deal on a 4-star hotel in Texas Medical Center just got simpler. Start by entering your chosen travel dates and length of your stay. Then sort the results by price and pick the option that best matches your style and budget.

  • Search for the lowest price from NT$2,450

What's the difference between 5-star and 4-star hotels in Texas Medical Center?
Offering a welcoming guest experience and upmarket décor, 4-star hotels are a fantastic option for your Texas Medical Center getaway. These types of stays generally come with loads of handy amenities that make it easy to unpack and unwind — think large beds, bathrobes, pools and restaurants. Or enjoy even more lavishness at a 5-star hotel designed to pamper with high-end perks and amenities. Full-service health clubs, complimentary toiletries and fine dining are typically featured at these swanky properties.