A red train on tracks, palm trees, and modern buildings.

Central San Diego 4 Stars Hotels

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Check availability on Central San Diego 4 Star Hotels

Tonight
Oct 15 - Oct 16
Tomorrow
Oct 16 - Oct 17
This weekend
Oct 16 - Oct 18
Next weekend
Oct 23 - Oct 25

Our top choices for Central San Diego 4-star hotels

An outdoor lounge area with seating, a fire feature, and a pool in the background.
A stone wall with a neon sign that reads "Tom & Jerry."
A spacious lobby with a bar area, leather armchairs, and a reception desk.
A modern restaurant with multiple seating areas, including booths and tables. There are hanging lights and a variety of plants.

1. Town and Country San Diego

Town and Country San Diego
Mission Valley
United States
Nelly
NT$5,770
NT$7,742 total
includes taxes & fees
Nov 10 - Nov 11
Town and Country San Diego
A bar area with a glass ceiling, a central bar counter, and multiple stools.
A dimly lit room with patterned walls, a wooden table, and a chair.
A large swimming pool with lounge chairs and umbrellas, surrounded by palm trees and a building with a striped facade.
A checkered floor with round tables and chairs, a patterned ceiling, and large windows.

2. Lafayette Hotel & Club

Lafayette Hotel & Club
University Heights
United States
Laurie
NT$8,782
NT$10,095 total
includes taxes & fees
Oct 19 - Oct 20
Lafayette Hotel & Club
An outdoor seating area with wicker chairs and a fire pit, surrounded by palm trees and string lights.
A spacious lobby with a central seating area, a staircase, and a view of the hallway leading to the entrance.
A poolside area with a concrete pool, lounge chairs, and a wooden deck.
A modern dining area with a large table, chairs, and hanging plants.

3. DoubleTree by Hilton Hotel San Diego - Mission Valley

DoubleTree by Hilton Hotel San Diego - Mission Valley
Mission Valley
United States
Alesi
NT$4,621
NT$5,312 total
includes taxes & fees
Nov 8 - Nov 9
DoubleTree by Hilton Hotel San Diego - Mission Valley
An outdoor dining area with tables and chairs, a fire feature, and a bar area with a stone wall and shelves.
A spacious gym with various exercise equipment, large windows, and a wooden floor.
A swimming pool with lounge chairs and umbrellas, surrounded by trees and a tall building in the background.
A hotel entrance with a covered outdoor seating area, palm trees, and a car parked in front.

4. San Diego Marriott La Jolla

San Diego Marriott La Jolla
University City
United States
Josh
NT$5,954
NT$6,848 total
includes taxes & fees
Oct 30 - Oct 31
San Diego Marriott La Jolla
An outdoor dining area with tables set for two, string lights overhead, and a view of a building in the background.
A spacious lobby with a modern staircase, comfortable seating, and large windows offering natural light.
A modern lobby with a large window, two sofas, and two black planters with plants.
An outdoor wedding venue with rows of chairs, floral centerpieces, and string lights.

5. Hilton San Diego Mission Valley

Hilton San Diego Mission Valley
Mission Valley
United States
Christian
NT$4,194
NT$4,821 total
includes taxes & fees
Nov 1 - Nov 2
Hilton San Diego Mission Valley
An outdoor patio with a stone fire pit, outdoor seating, string lights, and a tall, narrow heater.
A multi-level hotel lobby with dining areas, a reception desk, and a large TV screen.
A swimming pool with a visible water filtration system and a tiled edge.
A beach with clear skies, a rocky cliff, and a lighthouse in the distance.

6. Embassy Suites by Hilton San Diego La Jolla

Embassy Suites by Hilton San Diego La Jolla
University City
United States
Kunta
NT$5,441
NT$7,171 total
includes taxes & fees
Oct 30 - Oct 31
Embassy Suites by Hilton San Diego La Jolla
A spacious lobby with modern furniture, large windows, and a high ceiling with hanging lights.
A swimming pool with blue lounge chairs and umbrellas, surrounded by a building with balconies.
A modern interior with wooden panel ceilings, patterned seating, and a central bar area.
A hotel room with a large bed, a wooden nightstand, a bench, a desk with a TV, and a chair.

7. Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa
Mission Valley
United States
christopher
NT$5,179
NT$5,953 total
includes taxes & fees
Nov 8 - Nov 9
Legacy Resort Hotel & Spa
A spacious hotel lobby with a long reception desk, multiple seating areas, and large windows offering views of the outdoors.
A hotel room with two beds, a TV, a desk, and a chair.
A modern hotel with a flat roof, large windows, and a sign reading "DOLLYWOOD HOTEL".
A hotel room with two beds, a nightstand with a lamp, a framed picture on the wall, and a view through an open door.

8. DoubleTree by Hilton San Diego - Hotel Circle

DoubleTree by Hilton San Diego - Hotel Circle
Mission Valley
United States
Ramiro
NT$3,930
NT$4,518 total
includes taxes & fees
Oct 25 - Oct 26
DoubleTree by Hilton San Diego - Hotel Circle
A swimming pool with lounge chairs and a waterfall feature, surrounded by palm trees and a building with multiple balconies.
A modern lobby with a round table and four chairs, a reception desk, and a large window.
A modern outdoor seating area with a wooden wall, a hanging chair, and a large potted plant.
A modern hotel with a prominent tower, multiple floors, and a well-lit entrance.

9. San Diego Marriott Mission Valley

San Diego Marriott Mission Valley
Mission Valley
NT$5,115
NT$5,879 total
includes taxes & fees
Oct 25 - Oct 26
San Diego Marriott Mission Valley
An outdoor seating area with sofas, a fire pit, and tables covered with blue tablecloths.
A hotel room with a flat-screen TV, a desk with a chair, a small table with a lamp, a framed picture on the wall, and a large window with curtains.
A gym with exercise equipment, mirrors, and a wall-mounted TV.
A hotel room with two beds, a desk, a TV, and a window with a city view.

10. Hyatt Regency La Jolla

Hyatt Regency La Jolla
University City
United States
lisa
NT$6,820
NT$8,870 total
includes taxes & fees
Nov 7 - Nov 8
Hyatt Regency La Jolla
An outdoor patio with tables and chairs, string lights, and umbrellas.
Property amenity
A pool area with lounge chairs and umbrellas, surrounded by palm trees and a hilly landscape.
A hotel room with a large bed, a TV, a desk with a chair, and a view of the city through large windows.

11. Sheraton Mission Valley San Diego Hotel

Sheraton Mission Valley San Diego Hotel
Mission Valley
United States
Leanna
NT$5,758
NT$6,619 total
includes taxes & fees
Oct 25 - Oct 26
Sheraton Mission Valley San Diego Hotel
A narrow, enclosed walkway with wooden railings and a metal grid barrier, leading to a building entrance.
An outdoor seating area with sofas and chairs, a wooden staircase, and potted plants.
A modern reception desk with a glass top, a large window offering a view, and a potted plant.
A modern interior with concrete walls, wooden beams, and a central planter with plants.

12. City24 Hotel Little Italy Mission Hills

City24 Hotel Little Italy Mission Hills
Middletown
United States
Donavin
NT$3,697
NT$5,262 total
includes taxes & fees
Oct 26 - Oct 27
City24 Hotel Little Italy Mission Hills
BBQ/picnic area
Room
Private kitchen
Breakfast area

13. Residence Inn by Marriott San Diego Mission Valley

Residence Inn by Marriott San Diego Mission Valley
Mission Valley
United States
Kabnne
Residence Inn by Marriott San Diego Mission Valley
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Learn more about Central San Diego

Explore the seaside area of Central San Diego—a zoo, sports teams, and popular sights like San Diego Zoo.

See all hotels in Central San Diego
A historic cathedral with intricate architecture, a prominent bell tower, and a blue-domed structure.
Photo by Bilen Z

Top Central San Diego Hotel Reviews

Hilton San Diego Mission Valley

Hilton San Diego Mission Valley

10/10 Excellent
"Super friendly staff and clean"
Ashley 2-night trip
Posted 2 hours ago
Hilton San Diego Mission Valley
Town and Country San Diego

Town and Country San Diego

10/10 Excellent
"I appreciate the kind staff, the cleanliness of the room, hardwood floors (can't say enough) and the large patios. The food at the Mrkt hit the spot and the atmosphere was upbeat but not overbearing. I also enjoyed my pool view and 80s music backdrop."
April-Nicole 2-night trip
Posted 1 day ago
Town and Country San Diego

Frequently asked questions

How much does it cost to stay in a 4-star hotel in Central San Diego?
Expedia can help you easily locate the ideal 4-star hotel for your vacation in Central San Diego. Use our filter tool to tailor your search by things like price, conveniences and hotel star rating and get access to terrific deals in a couple of clicks.
  • Search for the lowest price from NT$4,518
What's the difference between 5-star and 4-star hotels in Central San Diego?
Offering a welcoming guest experience and upscale surroundings, 4-star hotels are a wonderful option for your Central San Diego escape. These kinds of stays generally feature loads of handy amenities that make it easy to unpack and unwind — think complimentary bathrobes, restaurants and pools. Or live in the lap of luxury at a 5-star hotel designed to spoil you with high-end perks and amenities. A personalized service, complimentary toiletries and gourmet dining are typically featured at these plush retreats.
Does Central San Diego have any 4-star all-inclusive resorts?
Finding your dream resort in Central San Diego is as simple as entering your travel dates and selecting our "All inclusive" filter. Stay and play where everything is already taken care of like your accommodations, food, activities and entertainment, or choose a standard 4-star resort in or around this leading destination.

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