A bench, a bicycle, and a lake surrounded by trees.

Find Resorts & Hotels with Spas in Upstate South Carolina, SC

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Check availability on Upstate South Carolina Resorts & Hotels with Spas

Tonight
Oct 6 - Oct 7
Tomorrow
Oct 7 - Oct 8
This weekend
Oct 9 - Oct 11
Next weekend
Oct 16 - Oct 18

Our top choices for Upstate South Carolina hotels with a spa

A spa room with two beds, a mural, and a reception desk.
A modern interior with a stone fireplace, leather sofas, and a wooden ceiling.
A large, multi-story house with a prominent waterfall in the foreground, surrounded by lush greenery.
A modern interior with a fireplace, plush seating, and a stone accent wall.

1. Grand Bohemian Lodge Greenville, Autograph Collection

Grand Bohemian Lodge Greenville, Autograph Collection
Greenville Downtown
  • Escape to a Tudor retreat with a full-service spa and rooftop garden overlooking the scenic river in Greenville.
NT$12,394
NT$14,042 total
includes taxes & fees
Oct 11 - Oct 12
Grand Bohemian Lodge Greenville, Autograph Collection
A modern hotel lobby with a chandelier, wooden shelving, a reception desk, and a view of the outdoors.
A modern interior with a large window, a chandelier, a dining area, and a hallway leading to a door.
A large, two-story house with a symmetrical facade, large windows, and a central entrance.
A cozy lounge area with leather armchairs, a central table, and a fireplace.

2. Hotel Hartness

Hotel Hartness
Greenville
  • Indulge in rejuvenating treatments at this upscale hotel with six couples spa rooms and scenic hiking trails for a peaceful escape.
NT$5,298
NT$7,051 total
includes taxes & fees
Oct 25 - Oct 26
Hotel Hartness
A two-story house with a tiled roof, a stone fire pit, and outdoor seating.
A swimming pool with lounge chairs and a building with balconies.
A bar with a large window view of mountains and a chandelier.
A reception area with a wooden reception desk, a large abstract painting, and a potted plant.

3. Hotel Domestique

Hotel Domestique
Travelers Rest
  • Retreat to this mountain hotel with therapeutic massage treatments, sauna, and seasonal outdoor pool for deep relaxation.
NT$13,313
NT$14,645 total
includes taxes & fees
Nov 1 - Nov 2
Hotel Domestique
Exterior
Dining
Terrace/patio
Interior

4. Bed & Breakfast on Tiffany Hill

Bed & Breakfast on Tiffany Hill
Mills River
NT$11,256
NT$12,691 total
includes taxes & fees
Oct 30 - Oct 31
Bed & Breakfast on Tiffany Hill
A hotel room with two beds, a desk, a chair, a mirror, and a window with curtains.
A modern bathroom with a glass shower enclosure, a white toilet, and a sink with a mirror above it.
A dining area with checkered flooring, multiple tables and chairs, and a decorative cabinet with various items.
A covered porch with a view of a street, two potted plants, and an American flag.

5. 1898 Waverly Inn

1898 Waverly Inn
Hendersonville
  • Experience spa bliss at this charming B&B with relaxing massage treatment rooms and attentive staff who ensure a rejuvenating stay.
NT$5,370
NT$6,054 total
includes taxes & fees
Nov 3 - Nov 4
1898 Waverly Inn
A wooden deck with chairs, surrounded by trees with autumn foliage.
A wooden deck with a spiral glass sculpture, potted plants, and a bench.
A hotel with a covered front porch, steps leading up to the entrance, and snow-covered bushes.
A cozy room with a fireplace, a bed, a sofa, and a wooden dresser.

6. The Orchard Inn

The Orchard Inn
Saluda
  • Enjoy a couples massage or solo Swedish retreat in this peaceful bed & breakfast with gardens and a 24-hour gym.
NT$9,504
NT$10,430 total
includes taxes & fees
Nov 1 - Nov 2
The Orchard Inn
A two-story wooden cabin with a balcony, a swimming pool, and a deck area.
A covered porch with rocking chairs and a small table with flowers.
A wooden interior with tables and chairs, a fireplace, and a stone wall.
A cozy room with a bed, a chair, a tray with snacks and wine, and a view of the outdoors.

7. Glen-Ella Springs Hotel & Restaurant

Glen-Ella Springs Hotel & Restaurant
Clarkesville
  • Relaxing country retreat with in-room massages and a serene garden setting for a rejuvenating spa experience.
NT$6,692
NT$7,653 total
includes taxes & fees
Oct 8 - Oct 9
Glen-Ella Springs Hotel & Restaurant
A hotel room with a bed, a bedside lamp, and a small table with candles.
A spacious dining area with multiple tables and chairs, large windows, and ornate chandeliers.
A swimming pool with lounge chairs and umbrellas, surrounded by autumn trees and a lake view.
A lakeside lodge with outdoor seating and string lights.

8. Greystone Inn

Greystone Inn
Lake Toxaway
  • Soak in mountain views at this lakeside retreat with couples' spa treatment rooms, yoga classes, and deep-tissue massages.
NT$15,644
NT$18,550 total
includes taxes & fees
Nov 5 - Nov 6
Greystone Inn
A massage therapy session in a spa setting with a massage table, towels, and various spa products.
A bedroom with a large bed, a nightstand, a desk, a chair, a sofa, a window, and a door.
A bedroom with a bed, a nightstand, a lamp, and a view of a balcony with outdoor furniture.
A modern kitchen with white cabinets, a stainless steel sink, and a wooden staircase leading to a balcony.

9. SKYLARANNA Resort & Spa

SKYLARANNA Resort & Spa
Hendersonville
  • Rejuvenate in a mountain spa retreat with 3 dedicated treatment rooms, hot tubs, and aromatherapy services along a scenic river.
NT$4,073
NT$5,667 total
includes taxes & fees
Oct 20 - Oct 21
SKYLARANNA Resort & Spa
Spa
Room
Aerial view
Yoga

10. The Horse Shoe Farm

The Horse Shoe Farm
Hendersonville
  • Relax in a mountain ranch sanctuary with 5 treatment rooms and outdoor spa areas for nature-inspired healing.
NT$14,298
NT$16,121 total
includes taxes & fees
Nov 1 - Nov 2
The Horse Shoe Farm
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Choose what matters most at spa hotels in Upstate South Carolina

Pool
Breakfast included
Hot tub
4 stars
5 stars

Top Upstate South Carolina Hotel Reviews

Hilton Greenville

Hilton Greenville

8/10 Good
"Nice, clean hotel. Unfortunately only one of the three elevators was working with a sold out weekend."
Ralph 2-night trip
Posted 7 hours ago
Hilton Greenville

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