Find Resorts & Hotels with Spas in Upstate South Carolina, SC
Change your mind
Book hotels with free cancellation
Be picky
Search almost a million properties worldwide
Check availability on Upstate South Carolina Resorts & Hotels with Spas
Top Upstate South Carolina Resorts & Hotels with Spas

Hotel Hartness
Hotel Hartness
9.8 out of 10, Exceptional, (570)
The price is NT$5,057
NT$6,574 total
includes taxes & fees
Aug 3 - Aug 4

SKYLARANNA Resort & Spa
SKYLARANNA Resort & Spa
8.4 out of 10, Very Good, (312)
The price is NT$3,819
NT$5,098 total
includes taxes & fees
Aug 4 - Aug 5

Trailborn Highlands
Trailborn Highlands
9.4 out of 10, Exceptional, (160)
The price is NT$5,348
NT$5,870 total
includes taxes & fees
Aug 3 - Aug 4

Echo Mountain Inn
Echo Mountain Inn
8.8 out of 10, Excellent, (530)
The price is NT$3,725
NT$4,162 total
includes taxes & fees
Aug 4 - Aug 5

Grand Bohemian Lodge Greenville, Autograph Collection
Grand Bohemian Lodge Greenville, Autograph Collection
9.6 out of 10, Exceptional, (364)
The price is NT$7,231
NT$7,954 total
includes taxes & fees
Aug 24 - Aug 25

Hotel Domestique
Hotel Domestique
9.6 out of 10, Exceptional, (30)
The price is NT$12,519
NT$13,771 total
includes taxes & fees
Aug 24 - Aug 25

Lake Rabun Hotel & Restaurant
Lake Rabun Hotel & Restaurant
8.6 out of 10, Excellent, (625)
The price is NT$4,279
NT$5,112 total
includes taxes & fees
Aug 10 - Aug 11

Lake Lure Inn and Spa
Lake Lure Inn and Spa
8.0 out of 10, Very Good, (38)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Upstate South Carolina Hotel Reviews

Embassy Suites Greenville Golf Resort & Conference Center
10/10 Excellent
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Find More Hotels near Upstate South Carolina
More Hotel Options in Upstate South Carolina
- Adults Only Resorts & Hotels in Upstate South Carolina
- Adventure Hotels in Upstate South Carolina
- Beach Hotels in Upstate South Carolina
- Boutique Hotels in Upstate South Carolina
- Business Hotels in Upstate South Carolina
- Cheap Hotels in Upstate South Carolina
- Family Hotels in Upstate South Carolina
- Golf Hotels in Upstate South Carolina
- Historic Hotels in Upstate South Carolina
- Hotel Wedding Venues in Upstate South Carolina
- Hotel with a Concierge in Upstate South Carolina
- Hotels with Bars in Upstate South Carolina
- Hotels with Early Check-in in Upstate South Carolina
- Hotels with Free Parking in Upstate South Carolina
- Hotels with Hot Tubs in Upstate South Carolina
- Hotels with WiFi in Upstate South Carolina
- Hotels with a Pool in Upstate South Carolina
- Hotels with an Indoor Pool in Upstate South Carolina
- Hotels with smoking rooms in Upstate South Carolina
- Luxury Hotels in Upstate South Carolina
- Pet-friendly Hotels in Upstate South Carolina
- Romantic Hotels in Upstate South Carolina
- Shopping Hotels in Upstate South Carolina
- Ski Hotels in Upstate South Carolina
More Accommodation Types in Upstate South Carolina
- Vacation Homes in South Carolina
- Condo Rentals in South Carolina
- Apartments in South Carolina
- Villas in South Carolina
- Cottages in South Carolina
- Motels in South Carolina
- Aparthotels in South Carolina
- B&B in South Carolina
- Resorts in South Carolina
- Guest Houses in South Carolina
- Condo Resorts in South Carolina
- Cabin Rentals in South Carolina
- Inns in South Carolina
- Chalets in South Carolina
- Country Houses in South Carolina
- Hostels in South Carolina
- Houseboats in South Carolina
- Lodges in South Carolina
- Town Houses in South Carolina
Hotels near popular Upstate South Carolina Attractions
- Hotels near Clemson University
- Hotels near Lake Keowee
- Hotels near BMW Performance Center
- Hotels near Falls Park on the Reedy
- Hotels near Bon Secours Wellness Arena
- Hotels near Greenville Convention Center
- Hotels near Haywood Mall
- Hotels near Lake Jocassee
- Hotels near The Peace Center
- Hotels near Lake Hartwell
Upstate South Carolina Hotels by Star Rating
Explore more hotels
- Hyatt Place Greenville/Haywood
- Wingate by Wyndham - Greenville-Airport
- Grand Bohemian Lodge Greenville, Autograph Collection
- Quality Inn & Suites Greenville - Haywood Mall
- Holiday Inn Greenville - Woodruff Road by IHG
- Days Inn by Wyndham Greenville
- Embassy Suites Greenville Golf Resort & Conference Center
- Best Western Greenville Airport Inn
- Horizon Inn & Suites
- ECHO Suites Extended Stay by Wyndham Spartanburg
- Comfort Suites At WestGate Mall
- Days Inn by Wyndham Spartanburg Waccamaw
- Spartanburg Marriott
- Holiday Inn Express & Suites Greenville Airport by IHG
- Best Western Spartanburg Northwest
- Holiday Inn Express Gaffney by IHG
- Microtel Inn & Suites by Wyndham Anderson/Clemson
- Days Inn by Wyndham Clinton / Laurens I-26
- Best Western Travelers Rest Greenville
- Baymont by Wyndham Easley/Greenville
Expedia's Latest Trends
Hotels
Flights
General
- Visit Bay Area
- Visit Cape Cod
- Visit Kauai
- Visit Upstate New York
- Visit Oregon Coast
- Visit North Central Texas
- Visit Southeast Florida
- Visit Hawaii Island
- Visit Fire Island
- Visit Puget Sound
- Visit Long Island
- Visit Napa Valley
- Visit Pumpkintown
- Visit Sonoma Valley
- Visit Oahu
- Visit Northeast Georgia
- Visit Nantucket Island
- Visit Silicon Valley
- Visit North Coast California
- Visit Catalina Island
- Visit Finger Lakes Region
- Visit Outer Banks