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Find Luxury Hotels in St. Charles, MO

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Check availability on St. Charles Luxury Hotels

Tonight
Aug 22 - Aug 23
Tomorrow
Aug 23 - Aug 24
Next weekend
Aug 28 - Aug 30
In two weeks
Sep 4 - Sep 6

Our top choices for St. Charles luxury hotels

1. Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
St. Charles
  • Indulge in lavish comfort at this St. Charles retreat featuring a full-service spa, seasonal pool, and 6 exceptional restaurants.
NT$4,701
NT$6,023 total
includes taxes & fees
Sep 7 - Sep 8
Ameristar Casino Resort and Spa

2. Drury Plaza Hotel St. Louis Brentwood

Drury Plaza Hotel St. Louis Brentwood
Brentwood
NT$4,333
NT$5,144 total
includes taxes & fees
Aug 30 - Aug 31
Drury Plaza Hotel St. Louis Brentwood

3. DoubleTree by Hilton St. Louis - Westport

DoubleTree by Hilton St. Louis - Westport
Westport
  • Experience luxury and comfort with premium pillowtop beds and hydromassage showers at this St. Louis hotel near the airport.
NT$3,971
NT$4,606 total
includes taxes & fees
Aug 30 - Aug 31
DoubleTree by Hilton St. Louis - Westport

4. DoubleTree by Hilton St. Louis Airport

DoubleTree by Hilton St. Louis Airport
Woodson Terrace
NT$3,762
NT$4,414 total
includes taxes & fees
Aug 30 - Aug 31
DoubleTree by Hilton St. Louis Airport

5. Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel
Berkeley
NT$3,759
NT$4,398 total
includes taxes & fees
Sep 6 - Sep 7
Renaissance St. Louis Airport Hotel

6. Le Méridien St. Louis Clayton

Le Méridien St. Louis Clayton
Clayton
NT$4,847
NT$5,707 total
includes taxes & fees
Aug 27 - Aug 28
Le Méridien St. Louis Clayton

7. Marriott St. Louis Airport

Marriott St. Louis Airport
Edmundson
NT$5,129
NT$6,121 total
includes taxes & fees
Aug 30 - Aug 31
Marriott St. Louis Airport

8. Hilton St. Louis Frontenac

Hilton St. Louis Frontenac
Frontenac
  • Upscale St. Louis retreat features pool, concierge, fine dining in prime business district.
NT$4,676
NT$5,447 total
includes taxes & fees
Aug 30 - Aug 31
Hilton St. Louis Frontenac

9. The Cheshire

The Cheshire
Richmond Heights
NT$4,972
NT$5,904 total
includes taxes & fees
Aug 23 - Aug 24
The Cheshire

10. Moonrise Hotel

Moonrise Hotel
Delmar Loop
  • Boutique retreat blends urban charm with luxury, from rooftop views to Egyptian cotton and rainfall showers.
NT$5,062
NT$6,021 total
includes taxes & fees
Sep 3 - Sep 4
Moonrise Hotel
View all properties

Top St. Charles Hotel Reviews

Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

8/10 Good
"The hotel was nice and rooms were clean and the casino was fun"
mike 1-night trip
Posted less than an hour ago
Hollywood Casino & Hotel St. Louis
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

8/10 Good
"The room was clean, but there was cracking in the shower. We were in the building that required you to take a second elevator. It did take forever to get hot water in the shower. Breakfast and dinner were good. We had a light go out, staff got it taken care of efficiently."
Dawn 2-night trip
Posted 2 hours ago
Drury Plaza Hotel St. Louis at the Arch
Forest Park Hotel by MDR

Forest Park Hotel by MDR

10/10 Excellent
"Perfect place to stay and affordable 👌 ✨️ close to downtown and other fun places to visit.."
wahwah 1-night trip
Posted 3 hours ago
Forest Park Hotel by MDR
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

10/10 Excellent
"We were traveling with 2 kids. The pool was awesome-salt, I believe. They even had pool noodles! The breakfast was like a restaurant; buffet and made to order, all included. Parking in the ramp was literally in the back of the building with a hallway into the hotel, super easy. Do eat or bring food back bc delivery and availability in the area was limited. 3 cheeseburger baskets was $76 with fees. Otherwise, easy to get to the zoo and other attractions."
carrie 2-night trip
Posted 7 hours ago
Clayton Plaza Hotel & Extended Stay
Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

10/10 Excellent
"Good place"
Anurag 3-night trip
Posted 18 hours ago
Pear Tree Inn St. Louis Near Union Station
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

10/10 Excellent
"Room was a great size for the money. Hotel was clean and quiet and easy to access from the garage. Great pool as well."
Stephanie 2-night trip
Posted 2 days ago
Ameristar Casino Resort and Spa

Frequently asked questions

Are you looking for a luxury hotel for your stay in St. Charles?
During your visit, you might want to enjoy the casinos and shopping which St. Charles is known for.
What's the best luxury hotel in St. Charles?
Ameristar Casino Resort and Spa is a luxury hotel with 6 restaurants and 2 bars, and it's a popular choice for Expedia travelers looking for an elegant place to stay.
When can I expect good weather in St. Charles?
Planning for the weather is an important factor for making your trip to St. Charles a success, especially when you're splurging. The hottest months are usually July and August with an average temp of 75°F, while the coldest months are January and February with an average of 37°F. Average annual precipitation for St. Charles is 46 inches.
What's there to see and do in St. Charles?
When you're in St. Charles, enjoy exploring the sights and attractions here including Historic Main Street, Frontier Park, and Katy Trail. If you have a little extra time during your trip, you might want to make a stop at Lewis & Clark Boathouse and Nature Center and St Charles Convention Center.

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