Santa Cruz Vacation Rentals

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Check prices for these dates

In two weeks
Mar 13 - Mar 15
In two months
Apr 24 - Apr 26
In three months
May 22 - May 24
In four months
Jun 19 - Jun 21

Our top choices for Santa Cruz vacation rentals

Blue Family | Terrace/patio

Cabin in Guarne

Cumbres Luxury Glamping
3.0 star property
9.0 out of 10, Wonderful, (4 reviews)
"Hot tub outside was an experience. Very clean "
United States
FRANK
The price is NT$5,639
NT$5,639 total
Mar 5 - Mar 6
Cumbres Luxury Glamping
1 bedroom, premium bedding, down comforters, free WiFi

Chalet in San Vicente

Shabbat Hotel Boutique
4.0 star property
10.0 out of 10, Exceptional, (2 reviews)
"Excelente Servicio y facilidades. 100% recomendado"
United States
william
Shabbat Hotel Boutique
Premium Cabin | Minibar, individually decorated, individually furnished, free WiFi

Cabin in Guarne

Wasikuna cabañas rurales tipo glamping
3.0 star property
10.0 out of 10, Exceptional, (4 reviews)
"Nice place "
United States
GERARDO
Wasikuna cabañas rurales tipo glamping
Suite (302) | Minibar, desk, laptop workspace, blackout drapes

Apartment in Rionegro

Mali Experience
3.0 star property
10.0 out of 10, Exceptional, (1 review)
"Espectacular apartamento y el sitio es muy bueno"
Colombia
Giovanni
The price is NT$2,508
NT$2,508 total
Mar 31 - Apr 1
Mali Experience
Superior Chalet, Balcony, Mountain View | Mountain view

Chalet in Girardota

Sky View Glamping
2.0 star property
9.0 out of 10, Wonderful, (2 reviews)
"Great view and the hospitality was very good.. The cabins were clean. "
United States
Chris
The price is NT$3,317
NT$3,317 total
Mar 8 - Mar 9
Sky View Glamping
Living area

Cabin in El Rosario

Skyline Ecoliving
3.0 star property
9.2 out of 10, Wonderful, (39 reviews)
"Best views ever! The staff was always amazing, and it was the perfect spot to escape the city noise for a little while."
United States
Andres
Skyline Ecoliving
Outdoor pool

Condo in Rionegro

PORTANOVA SUITES by ADVENTU
3.0 star property
8.8 out of 10, Excellent, (44 reviews)
"Room was very clean and apt is very quiet and close to the hospital "
United States
FERNANDO
PORTANOVA SUITES by ADVENTU
Deluxe Apartment, Garden View | Desk, laptop workspace, blackout drapes, soundproofing

Apartment in Rionegro

Edificio Cielo Verde
3.0 star property
The price is NT$4,312
NT$5,142 total
Mar 31 - Apr 1
Edificio Cielo Verde
Studio | View from room

Condo in Rionegro

Travelers Rio Verde Living Suites
3.5 star property
8.4 out of 10, Very Good, (470 reviews)
"GOOD PLACE TO STAY THE NIGHT NEAR THE AIRPORT"
United States
Robert
Travelers Rio Verde Living Suites
Standard Room, Patio, Mountain View | Outdoor dining

Cabin in Rionegro

Almaia 17
3.0 star property
The price is NT$4,146
NT$12,605 total
Mar 31 - Apr 1
Almaia 17
15 outdoor pools

Villa in Rionegro

Llano Grande
3.5 star property
Llano Grande
Front of property

Aparthotel in Rionegro

Hotel Rioverde- 5 minutos de cercanía al aeropuerto
4.5 star property
7.4 out of 10, Good, (57 reviews)
"Clean room and good amenities. Close to the airport which was useful after a long flight "
Australia
DAVID
Hotel Rioverde- 5 minutos de cercanía al aeropuerto
Exterior

Vacation Home in San Jerónimo

La Gracia Hotel & Spa
2.5 star property
8.8 out of 10, Excellent, (5 reviews)
"Muy bonita la propiedad, limpio, buena comida No me gusto el ruido continuo de otras propiedades"
Mexico
Andres
The price is NT$6,605
NT$6,605 total
Mar 11 - Mar 12
La Gracia Hotel & Spa
Front of property

Apartment in El Poblado

Seissta Medellin
4.0 star property
9.2 out of 10, Wonderful, (224 reviews)
"Excellent staff outstanding service the best "
United States
Santiago
The price is NT$3,314
NT$3,314 total
Mar 4 - Mar 5
Seissta Medellin
Comfort Apartment, 2 Bedrooms, Kitchenette | Premium bedding, down comforters, minibar, free WiFi

Aparthotel in Buenos Aires

Hotel Moore 45
4.0 star property
8.0 out of 10, Very Good, (1 review)
The price is NT$744
NT$744 total
Mar 1 - Mar 2
Hotel Moore 45
3 connected bedroom unit with hot tub and balcony | Private spa tub

Aparthotel in El Poblado

Haven, A Design Hotel
4.0 star property
8.8 out of 10, Excellent, (664 reviews)
"This hotel was amazing. The staff was great and my overall stay was 10/10"
United States
Alvin Ammaad
The price is NT$2,996
NT$2,996 total
Mar 3 - Mar 4
Haven, A Design Hotel
Deluxe Apartment, 1 Queen Bed with Sofa bed, Non Smoking, Kitchen | 1 bedroom, premium bedding, down comforters, in-room safe

Aparthotel in Medellín

Portal del Rodeo ApartaHotel - Arkadia Mall
3.5 star property
9.0 out of 10, Wonderful, (268 reviews)
"the staff was very friendly good food and the room is so nice highly recomended"
United States
Astrid
The price is NT$1,963
NT$1,963 total
Mar 8 - Mar 9
Portal del Rodeo ApartaHotel - Arkadia Mall
Deluxe Cabin, Balcony, Mountain View

Chalet in Medellin

Onirico Luxury
2.0 star property
The price is NT$2,626
NT$2,626 total
Mar 2 - Mar 3
Onirico Luxury
Front of property

Apartment in El Poblado

Nomadic Suites
3.5 star property
9.6 out of 10, Exceptional, (4 reviews)
"Hotel nuevo, excelentes instalaciones, limpieza impecable, solo un detalle, solicité habitación para 4 personas y tenía una cama queen y sofá cama, solo que el sofá cama era algo incómodo para descanzar, de lo demás estuvo excelente."
Mexico
Moisés
Nomadic Suites
Rooftop terrace

Aparthotel in El Poblado

York Medellin, Curio Collection by Hilton
4.0 star property
9.6 out of 10, Exceptional, (1,484 reviews)
"Great staff, pool and amenities!"
United States
alba
The price is NT$5,497
NT$5,497 total
Mar 22 - Mar 23
York Medellin, Curio Collection by Hilton
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Cruz Hotel Reviews

The Click Clack Hotel Medellin

The Click Clack Hotel Medellin

10/10 Excellent
"Great place overall, location, staff, room were all nice."
Jeffrey W 4-night trip
Posted 1 day ago
The Click Clack Hotel Medellin

Find out more about Santa Cruz

Search for holiday rentals in Santa Cruz on Expedia! You can easily find your home rentals, villas, holiday apartments in Santa Cruz using one of the methods below:

  • View our selection of featured holiday rentals in Santa Cruz
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Look no further and take a look at our great range of rental properties in Santa Cruz!

Frequently asked questions

Can I find a vacation rental in Santa Cruz?

Yes, we offer vacation rentals close to popular attractions in Santa Cruz, or you can choose a more secluded option if you want a relaxing place to stay.

What's the top vacation rental in Santa Cruz?

EP Casa Uribe Architecture Art & Nature: You might want to consider this vacation home rental near Santa Cruz, which is located in a shopping district and has an outdoor pool, a balcony, and laundry facilities to put you at ease in your new surroundings. Kitchen amenities include a dishwasher, a fridge, and a stovetop.

What’s there to see and do in Santa Cruz?

While exploring the area, visit family-friendly sights like Pueblito Paisa, or get outside and enjoy nature at Medellin Botanical Garden. In the larger area, you’ll find University of Antioquia and Arvi Park.

What’s a vacation rental in Santa Cruz like?

Vacation rentals are private properties where you can stay for a long or short time in Santa Cruz. Vacation rentals feature extras such as hot tubs, fire pits, and patios so you'll feel just like you're at home. If you're concerned about cleanliness, a vacation rental can offer a sense of safety away from public hotel elevators and lobbies bustling with people while still allowing you the excitement and enjoyment of travel. You'll also have more space in a vacation rental than in a standard hotel, which is another reason why a vacation rental is an attractive option for families.