Santa Cruz Vacation Rentals

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Check prices for these dates

In two weeks
May 1 - May 3
In two months
Jun 12 - Jun 14
In three months
Jul 10 - Jul 12
In four months
Aug 7 - Aug 9

Our top choices for Santa Cruz vacation rentals

Standard Room, Patio, Mountain View | Outdoor dining

Almaia 17

Almaia 17
3.0 star property
Rionegro
The price is NT$1,652
NT$3,924 total
Apr 21 - Apr 22
Almaia 17
Interior

Casagrande

Casagrande
2.0 star property
Rionegro
10.0 out of 10, Exceptional, (1 review)
"Very nice large room with king size bed, very low noise beautiful Mountain View’s. It was a little cold for pool but, various shopping centers close to property and public transport passes right in front. Awesome place to stay."
United States
Alex
The price is NT$1,748
NT$1,748 total
Apr 18 - Apr 19
Casagrande
Outdoor pool

PORTANOVA SUITES by ADVENTU

PORTANOVA SUITES by ADVENTU
3.0 star property
Rionegro
8.4 out of 10, Very Good, (52 reviews)
"Room was very clean and apt is very quiet and close to the hospital "
United States
FERNANDO
The price is NT$1,444
NT$1,969 total
Apr 21 - Apr 22
PORTANOVA SUITES by ADVENTU
Living area

Skyline Ecoliving

Skyline Ecoliving
3.0 star property
El Rosario
9.2 out of 10, Wonderful, (42 reviews)
"Super impressive mountain view directly visible as soon as you open your eyes in the morning. "
United States
Antranik
The price is NT$2,117
NT$2,535 total
Apr 23 - Apr 24
Skyline Ecoliving
Suite (302) | Minibar, desk, laptop workspace, blackout drapes

Mali Experience

Mali Experience
3.0 star property
Rionegro
10.0 out of 10, Exceptional, (2 reviews)
"My room was a well-equipped luxury studio apartment that included a washer/dryer (what a treat) and a great small kitchen and a large walk-in shower. Absolutely loved my accommodation. And for you gringos and gringas out there with shaky Spanish, your host, Juan, not only speaks impeccable English but is so very helpful. Highly recommend!"
United States
Gabrielle
The price is NT$2,379
NT$2,379 total
Apr 18 - Apr 19
Mali Experience
Room

hotel civitas medellin

hotel civitas medellin
2.5 star property
La Candelaria
10.0 out of 10, Exceptional, (1 review)
"Hotel in a good location, comfortable and has a great staff."
United States
Valencia
The price is NT$801
NT$801 total
Apr 23 - Apr 24
hotel civitas medellin
Comfort Apartment, 2 Bedrooms, Kitchenette | Premium bedding, down comforters, minibar, free WiFi

Hotel Moore 45

Hotel Moore 45
4.0 star property
Buenos Aires
8.0 out of 10, Very Good, (1 review)
The price is NT$780
NT$780 total
Apr 27 - Apr 28
Hotel Moore 45
1 bedroom, premium bedding, down comforters, free WiFi

Shabbat Hotel Boutique

Shabbat Hotel Boutique
4.0 star property
San Vicente
10.0 out of 10, Exceptional, (2 reviews)
"Excelente Servicio y facilidades. 100% recomendado"
United States
william
The price is NT$4,042
NT$4,042 total
May 1 - May 2
Shabbat Hotel Boutique
Studio | View from room

Travelers Rio Verde Living Suites

Travelers Rio Verde Living Suites
3.5 star property
Rionegro
8.4 out of 10, Very Good, (473 reviews)
"GOOD PLACE TO STAY THE NIGHT NEAR THE AIRPORT"
United States
Robert
The price is NT$2,295
NT$2,295 total
Apr 19 - Apr 20
Travelers Rio Verde Living Suites
Reception

Praia Apartaestudios

Praia Apartaestudios
4.5 star property
Sabaneta
8.0 out of 10, Very Good, (15 reviews)
"It nice and comfortable. "
United States
DENIS
The price is NT$1,114
NT$1,114 total
May 1 - May 2
Praia Apartaestudios
Front of property

Hotel Rioverde- 5 minutos de cercanía al aeropuerto

Hotel Rioverde- 5 minutos de cercanía al aeropuerto
4.5 star property
Rionegro
7.4 out of 10, Good, (60 reviews)
"Clean room and good amenities. Close to the airport which was useful after a long flight "
Australia
DAVID
The price is NT$3,124
NT$3,124 total
Apr 19 - Apr 20
Hotel Rioverde- 5 minutos de cercanía al aeropuerto
Deluxe Apartment, City View | Premium bedding, down comforters, Select Comfort beds, minibar

Royal Living Poblado

Royal Living Poblado
4.0 star property
El Poblado
9.0 out of 10, Wonderful, (67 reviews)
"Great"
United States
Ryan
The price is NT$1,815
NT$1,815 total
Apr 24 - Apr 25
Royal Living Poblado
Staircase

zenia

zenia
3.0 star property
Laureles
9.4 out of 10, Exceptional, (46 reviews)
"Wonderful place. Brilliant staff."
United States
Moriah
The price is NT$955
NT$955 total
Apr 19 - Apr 20
zenia
Exterior

Candelaria Campestre

Candelaria Campestre
2.0 star property
El Carmen de Viboral
The price is NT$3,059
NT$3,846 total
Apr 18 - Apr 19
Candelaria Campestre
Restaurant

Edificio Helena

Edificio Helena
3.0 star property
Medellín
9.2 out of 10, Wonderful, (59 reviews)
"For being a last minute stay, this place was better than expected and highly recommended. The rooftop is has a spectacular view of Medellin. "
United States
Michael
The price is NT$1,227
NT$1,227 total
Apr 19 - Apr 20
Edificio Helena
Reception

Sites Hotel

Sites Hotel
4.0 star property
El Poblado
9.2 out of 10, Wonderful, (1,144 reviews)
"Everything was great, and the staff were so helpful and nice all the time, will definitely be back. "
United States
Romulo
The price is NT$3,155
NT$3,155 total
Apr 24 - Apr 25
Sites Hotel
Balcony

Miracle Building

Miracle Building
3.5 star property
El Poblado
8.8 out of 10, Excellent, (26 reviews)
"Great place will definitely stay again"
United States
justin ryan
Miracle Building
City Apartment | Private kitchen | Full-size fridge, microwave, oven, blender

Apto muy bien ubicado- Home ARIS 401

Apto muy bien ubicado- Home ARIS 401
3.5 star property
La Candelaria
10.0 out of 10, Exceptional, (1 review)
"O apartamento é muito bem localizado e organizado, Dona Iolanda muito prestativa e atenciosa."
Brazil
Ricardo
The price is NT$884
NT$1,672 total
May 1 - May 2
Apto muy bien ubicado- Home ARIS 401
Deluxe Apartment, 1 Queen Bed with Sofa bed, Non Smoking, Kitchen | 1 bedroom, premium bedding, down comforters, in-room safe

Portal del Rodeo ApartaHotel - Arkadia Mall

Portal del Rodeo ApartaHotel - Arkadia Mall
3.5 star property
Medellín
9.2 out of 10, Wonderful, (271 reviews)
"the staff was very friendly good food and the room is so nice highly recomended"
United States
Astrid
The price is NT$1,966
NT$1,966 total
Apr 18 - Apr 19
Portal del Rodeo ApartaHotel - Arkadia Mall
Deluxe Studio, Balcony, City View | Living area | 45-inch Smart TV with digital channels

Hotel Santa Ana

Hotel Santa Ana
4.0 star property
El Poblado
9.0 out of 10, Wonderful, (20 reviews)
"Very clean and comfortable. Close to public transportation. Great food with lots of choices. Great staff and service. "
United States
Juan Vicente
The price is NT$1,680
NT$1,680 total
Apr 21 - Apr 22
Hotel Santa Ana
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Cruz Hotel Reviews

Calle Flora Hotel by Jalo

Calle Flora Hotel by Jalo

10/10 Excellent
"I love the hotel the room comfortable clean and beautiful the view amazing location perfect the price super economic . My next trip to the same hotel!! Thank you"
Antonia medero 3-night trip
Posted 10 hours ago
Calle Flora Hotel by Jalo

Find out more about Santa Cruz

Search for holiday rentals in Santa Cruz on Expedia! You can easily find your home rentals, villas, holiday apartments in Santa Cruz using one of the methods below:

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Look no further and take a look at our great range of rental properties in Santa Cruz!

Frequently asked questions

Can I find a vacation rental in Santa Cruz?

Yes, we offer vacation rentals close to popular attractions in Santa Cruz, or you can choose a more secluded option if you want a relaxing place to stay.

What’s there to see and do in Santa Cruz?

While exploring the area, visit family-friendly sights like Pueblito Paisa, or get outside and enjoy nature at Medellin Botanical Garden. In the larger area, you’ll find University of Antioquia and Arvi Park.

What’s a vacation rental in Santa Cruz like?

Vacation rentals are private properties where you can stay for a long or short time in Santa Cruz. Vacation rentals feature extras such as hot tubs, fire pits, and patios so you'll feel just like you're at home. If you're concerned about cleanliness, a vacation rental can offer a sense of safety away from public hotel elevators and lobbies bustling with people while still allowing you the excitement and enjoyment of travel. You'll also have more space in a vacation rental than in a standard hotel, which is another reason why a vacation rental is an attractive option for families.