A colonial-style building with a bell tower, palm trees, and a paved walkway.

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Oct 11 - Oct 12
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Oct 12 - Oct 13
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Our top choices for Santa Cruz hotels

1. TRYP by Wyndham Santa Cruz

TRYP by Wyndham Santa Cruz
Equipetrol
United States
Matias
NT$3,480
NT$3,480 total
Oct 12 - Oct 13
TRYP by Wyndham Santa Cruz

2. Camino Real Hotel

Camino Real Hotel
Santa Cruz
United States
Wendy
NT$5,252
NT$5,252 total
Oct 12 - Oct 13
Camino Real Hotel

3. Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Equipetrol
United States
Daniel
NT$4,315
NT$4,315 total
Nov 7 - Nov 8
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

4. Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
Santa Cruz
United States
Scott
NT$2,350
NT$2,350 total
Oct 15 - Oct 16
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

5. Sun Hotel

Sun Hotel
Santa Cruz
United States
Ivan
NT$3,448
NT$3,448 total
Oct 12 - Oct 13
Sun Hotel

6. Ibis Santa Cruz DE LA Sierra

Ibis Santa Cruz DE LA Sierra
Equipetrol
United States
Hui Hua
NT$1,267
NT$1,267 total
Oct 26 - Oct 27
Ibis Santa Cruz DE LA Sierra

7. Lido Hotel

Lido Hotel
Centro Histórico
United States
Gabrielle
NT$802
NT$802 total
Oct 15 - Oct 16
Lido Hotel

8. Hotel Cortez

Hotel Cortez
Equipetrol
United States
Rigoberto
NT$4,138
NT$4,138 total
Nov 6 - Nov 7
Hotel Cortez

9. Hotel Las Américas

Hotel Las Américas
Centro Histórico
Canada
Stanley
NT$833
NT$833 total
Oct 12 - Oct 13
Hotel Las Américas

10. HOTEL OSHO

HOTEL OSHO
Santa Cruz
Canada
David
NT$1,612
NT$1,612 total
Oct 23 - Oct 24
HOTEL OSHO

11. Marriott Santa Cruz de la Sierra Hotel

Marriott Santa Cruz de la Sierra Hotel
Santa Cruz
United States
Deivis
NT$3,377
NT$3,377 total
Nov 1 - Nov 2
Marriott Santa Cruz de la Sierra Hotel

12. Alfonsina Hotel Boutique by Inboccaluppo

Alfonsina Hotel Boutique by Inboccaluppo
Equipetrol
United States
Elizabeth
NT$3,442
NT$3,442 total
Oct 16 - Oct 17
Alfonsina Hotel Boutique by Inboccaluppo

13. Apart Hotel Premium Suites Santa Cruz

Apart Hotel Premium Suites Santa Cruz
Santa Cruz
United States
Ruben
NT$862
NT$862 total
Oct 12 - Oct 13
Apart Hotel Premium Suites Santa Cruz

14. Chairú Eco Hotel

Chairú Eco Hotel
Santa Cruz
United States
Luis
NT$1,509
NT$1,509 total
Nov 1 - Nov 2
Chairú Eco Hotel

15. Cosmopolitano Hotel Boutique

Cosmopolitano Hotel Boutique
Centro Histórico
United States
Rajendra
NT$1,700
NT$1,700 total
Nov 2 - Nov 3
Cosmopolitano Hotel Boutique

16. Premium Suites Deluxe Aparthotel Equipetrol

Premium Suites Deluxe Aparthotel Equipetrol
Santa Cruz
United States
Luisa
NT$1,469
NT$1,469 total
Oct 19 - Oct 20
Premium Suites Deluxe Aparthotel Equipetrol

17. Hotel Arenal

Hotel Arenal
Centro Histórico
United States
Max
NT$1,685
NT$1,685 total
Oct 17 - Oct 18
Hotel Arenal

18. Swissôtel Santa Cruz De La Sierra

Swissôtel Santa Cruz De La Sierra
Santa Cruz
United States
GONZALO
NT$4,189
NT$4,189 total
Nov 3 - Nov 4
Swissôtel Santa Cruz De La Sierra

19. Novotel Santa Cruz De La Sierra

Novotel Santa Cruz De La Sierra
Santa Cruz
United States
ERNESTO
NT$3,946
NT$3,946 total
Oct 26 - Oct 27
Novotel Santa Cruz De La Sierra

20. Hotel G

Hotel G
Santa Cruz
Mexico
JACOB
NT$876
NT$876 total
Nov 9 - Nov 10
Hotel G
View all properties

Vacation Rentals in Santa Cruz

Apartment

Apart Hotel Premium Suites Santa Cruz

Apart Hotel Premium Suites Santa Cruz
Santa Cruz
"Great location."
Apart Hotel Premium Suites Santa Cruz
Aparthotel

Premium Suites Deluxe Aparthotel Equipetrol

Premium Suites Deluxe Aparthotel Equipetrol
Santa Cruz
"great place to stay!"
Premium Suites Deluxe Aparthotel Equipetrol
Aparthotel

Terranova Suites

Terranova Suites
Santa Cruz
"Easy to access"
Terranova Suites
Aparthotel

Equipetrol Suites Apart Hotel

Equipetrol Suites Apart Hotel
Santa Cruz
"Perfect hotel"
Equipetrol Suites Apart Hotel
Apartment

AMERICA APARTMENTS

AMERICA APARTMENTS
Santa Cruz
"Clean room, great staff "
AMERICA APARTMENTS
Aparthotel

Apart Hotel Toborochi

Apart Hotel Toborochi
Equipetrol
"Very comfortable and quiet place and very good location. "
Apart Hotel Toborochi
Vacation Home

Casa Vida

Casa Vida
Santa Cruz
"buena recepción, el lugar es muy bueno un poco alejado de la ciudad, falta comodidad en algunos aspectos pero la casa es grande y espaciosa"
Casa Vida
See all vacation rentals

Hotels recommended for families in Santa Cruz

Ibis Santa Cruz DE LA Sierra

Ibis Santa Cruz DE LA Sierra
Equipetrol
NT$1,267
NT$1,267 total
Oct 26 - Oct 27
Ibis Santa Cruz DE LA Sierra

Marriott Santa Cruz de la Sierra Hotel

Marriott Santa Cruz de la Sierra Hotel
Santa Cruz
NT$3,377
NT$3,377 total
Nov 1 - Nov 2
Marriott Santa Cruz de la Sierra Hotel

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
Santa Cruz
NT$2,350
NT$2,350 total
Oct 15 - Oct 16
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Sun Hotel

Sun Hotel
Santa Cruz
NT$3,448
NT$3,448 total
Oct 12 - Oct 13
Sun Hotel

Lido Hotel

Lido Hotel
Centro Histórico
NT$802
NT$802 total
Oct 15 - Oct 16
Lido Hotel

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Equipetrol
NT$4,315
NT$4,315 total
Nov 7 - Nov 8
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Hotel Las Américas

Hotel Las Américas
Centro Histórico
NT$833
NT$833 total
Oct 12 - Oct 13
Hotel Las Américas

Cosmopolitano Hotel Boutique

Cosmopolitano Hotel Boutique
Centro Histórico
NT$1,700
NT$1,700 total
Nov 2 - Nov 3
Cosmopolitano Hotel Boutique
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Where to stay in Santa Cruz

Find the best Santa Cruz areas and neighborhoods for the activities you enjoy most.Learn more about Santa Cruz
Learn more about Santa Cruz

Equipetrol

Though Equipetrol might not have many top sights, you can venture to the surrounding area to see attractions like Santa Cruz Zoo and Municipal Library.

Centro Histórico

If you're spending some time in Centro Histórico, Plaza 24 de Septiembre and La Recova Artisan Walk are top sights worth seeing.

Hamacas

While Hamacas isn't home to many top sights, Las Brisas Shopping Center and Santa Cruz Zoo are some notable places to visit nearby.

Zona Sur (South Zone)

Zona Sur (South Zone) might not have many top sights, but Ramon Tahuichi Aguilera Stadium and Plaza 24 de Septiembre are two attractions nearby that you can check out.

Urubó

While Urubó might not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Guembe Biocenter and Ventura Mall.

Stay near popular Santa Cruz attractions

A historic building with arched windows and a clock. People are sitting and standing on the steps in front of the building.

Plaza 24 de Septiembre

8.8/10 (164 reviews)
Plaza 24 de Septiembre buzzes with local culture beneath swaying palms and colonial architecture. Climb the Cathedral's bell tower for spectacular city views while sampling authentic Bolivian coffee from vendors.
See properties
A historic tower with a clock, surrounded by lush greenery and palm trees.

San Lorenzo Cathedral

9.0/10 (84 reviews)
This grand neoclassical cathedral dominates Santa Cruz's skyline with its towering spires and ornate façade. Climb the bell tower at sunset for breathtaking panoramic views of the city.
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Ventura Mall

9.0/10 (183 reviews)
Ventura Mall, Santa Cruz's premier shopping destination, features international brands and local boutiques. Enjoy the cinema complex, food court, and entertainment options in this contemporary Bolivian retail hub.
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Guembe Biocenter

8.8/10 (60 reviews)
This vibrant ecological sanctuary showcases hundreds of butterfly species in a lush, tropical environment. Explore walking trails, enjoy boat rides, and learn about biodiversity in this serene natural retreat.
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Ramon Tahuichi Aguilera Stadium

8.4/10 (18 reviews)
This multi-purpose stadium hosts Bolivia's most passionate football rivalries and tournaments. Experience the electric atmosphere of a local derby while enjoying modernized facilities and vibrant Santa Cruz culture.
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Las Brisas Shopping Center

8.4/10 (40 reviews)
This modern complex offers 80+ stores, a nine-screen cinema, and a unique outdoor restaurant promenade. Explore the gastronomic boulevard for dining experiences beyond the standard food court options.
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Santa Cruz Zoo

8.4/10 (53 reviews)
The Santa Cruz Municipal Zoo showcases Bolivia's native wildlife in naturalistic habitats, featuring jaguars, tapirs, and free-ranging sloths. Morning visits offer the best chance to see active animals.
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Blacutt Square

8.2/10 (19 reviews)
Plaza Blacutt offers a verdant escape in Santa Cruz with mature trees shading tiled pathways. Enjoy local flavors from vendors along the northern edge while children play in the well-equipped playground areas.
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Learn more about Santa Cruz

Tropical energy pulses through Plaza 24 de Septiembre, where locals gather under palm trees and the Metropolitan Cathedral's twin towers stand watch. Biocentro Güembé offers rainforest trails with butterfly gardens, while the massive Ventura Mall provides air-conditioned shopping when afternoon temperatures climb.

See all hotels in Santa Cruz
A historic cathedral with two prominent towers, surrounded by urban buildings and palm trees.

Top Santa Cruz Hotel Reviews

Hotel Cortez

Hotel Cortez

10/10 Excellent
"Most amazing hotel staff ever. Thanks for making this a special stay. good food, but the staff goes the extra mile to make it special. Gracias!!"
Fabio 7-night trip
Posted 22 hours ago
Hotel Cortez
Sun Hotel

Sun Hotel

8/10 Good
"A super convenient hotel with spacious rooms and nice grounds. Perfect for a layover on long flights Shuttle service great. Loved our balcony overlooking the pool , sitting with a cup of tea listening to the birds and chilling before a long flight home"
stephanie 1-night trip
Posted 4 days ago
Sun Hotel
TRYP by Wyndham Santa Cruz

TRYP by Wyndham Santa Cruz

10/10 Excellent
"."
Matias 4-night trip
Posted 4 days ago
TRYP by Wyndham Santa Cruz
Lido Hotel

Lido Hotel

10/10 Excellent
"Very convenient place to stay Clean and very affordable Good staff"
Remberto 3-night trip
Posted 7 days ago
Lido Hotel
Chairú Eco Hotel

Chairú Eco Hotel

8/10 Good
"The breakfast was not that good, but everything was good"
Olga Lidia 2-night trip
Posted 2 weeks ago
Chairú Eco Hotel
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

10/10 Excellent
"The room was very clean and the breakfast was fantastic. Overall it was a great experience."
Scott 7-night trip
Posted 1 month ago
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
Novotel Santa Cruz De La Sierra

Novotel Santa Cruz De La Sierra

10/10 Excellent
"All around good price and location"
Alejandro 1-night trip
Posted 2 months ago
Novotel Santa Cruz De La Sierra
Delfines Collection Hotel By Mercure

Delfines Collection Hotel By Mercure

10/10 Excellent
"Todo muy bien"
lady 2-night trip
Posted 2 months ago
Delfines Collection Hotel By Mercure

More cheap stays in Santa Cruz

Equipetrol Suites Apart Hotel

Equipetrol Suites Apart Hotel

Equipetrol Santa Cruz Departamento de Santa Cruz
NT$1,641
NT$1,641 total
Oct 12 - Oct 13
Equipetrol Suites Apart Hotel
Ibiza Hostel

Ibiza Hostel

445 Santa Cruz Departamento de Santa Cruz
Get ratesIbiza Hostel
Amaca Hostal

Amaca Hostal

249 Independencia Santa Cruz Departamento de Santa Cruz
Get ratesAmaca Hostal
Casa Por Temporadas

Casa Por Temporadas

Barrio Las Pampitas, calle 3 Nro. 99 Santa Cruz Santa Cruz Department
Get rates
10/10 Exceptional! (1 review)
Casa Por Temporadas
HOTEL CASA BLANCA

HOTEL CASA BLANCA

Avenida Marcelo Terceros Zona Equipetrol Santa Cruz Santa Cruz de la Sierra
Get ratesHOTEL CASA BLANCA
Hotel Viru Viru II

Hotel Viru Viru II

Av. Alameda 72 - Zona Valle Sanchez Santa Cruz Santa Cruz de la Sierra
Get rates
4.8/10 (3 reviews)
Hotel Viru Viru II

Find out more about Santa Cruz

Top reasons to visit Santa Cruz

  • Vibrant City Life: Santa Cruz boasts a lively city center with bustling shopping centers, exciting nightlife, and a variety of entertainment options.
  • Cultural Richness: Visitors can explore stunning cathedrals, vibrant piazzas, and local landmarks that highlight the city’s cultural heritage.
  • Outdoor Adventures: Enjoy outdoor activities that showcase Santa Cruz's beautiful surroundings, including parks and recreational areas.
  • Delicious Local Cuisine: Savor a range of delicious meals at local restaurants, offering a taste of Bolivian flavors.
  • Comfortable Accommodations: A variety of motels and hotels cater to different needs, ensuring a comfortable stay for every traveler.

Find great hotels in Santa Cruz

Explore a variety of hotel accommodations in Santa Cruz, Bolivia, catering to every traveler's needs. Whether you're looking for a business-friendly hotel, a family-oriented stay, or a pet-friendly environment, you'll find excellent options here. With numerous hotels and hostels available, you can easily read reviews and discover the best places to stay for an unforgettable vacation experience in this vibrant city.

  • Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel: Nestled in the vibrant heart of Santa Cruz, Los Tajibos is a delightful retreat that seamlessly blends business and leisure. This 3.5-star hotel is particularly family-friendly, offering essential amenities for children, including a First Aid Kit. With spacious accommodations and a welcoming atmosphere, this hotel is perfect for travelers seeking a comfortable base for both work and play. Guests can enjoy the lush gardens, modern facilities, and exceptional service, making it an ideal choice for a memorable stay.
  • Hotel Cortez: Experience relaxation at Hotel Cortez, a refined 3.5-star hotel that caters to business travelers and wellness enthusiasts alike. This property features a full-service spa where guests can indulge in various treatments, including massages and access to a hot tub. With a focus on rejuvenation, the hotel also boasts a refreshing pool area and an inviting ambiance that promotes relaxation. Whether you're on a business trip or a spa-themed getaway, Hotel Cortez provides an excellent environment to unwind and recharge.
  • Buganvillas Hotel Suites & Spa: Buganvillas Hotel Suites & Spa stands out as a luxurious 4-star family-friendly accommodation in Santa Cruz. This hotel is designed to cater to families, featuring amenities such as a children’s pool and cribs available for a fee. The spacious suites offer a comfortable and home-like atmosphere, making it an excellent choice for family vacations. With a focus on both relaxation and fun, Buganvillas provides a well-rounded experience, ensuring that both parents and children enjoy their stay in this beautiful destination.

Where to stay near Santa Cruz

Santa Cruz, Bolivia, offers a vibrant blend of culture and excitement, making it an ideal destination for families and city-themed vacations. Explore the lively city center, where you'll find exciting venues and a bustling nightlife. Nearby neighborhoods like San Francisco and the West Coast provide unique experiences with friendly locals and picturesque surroundings. Whether you're seeking excursions or cultural immersion, Santa Cruz promises an unforgettable adventure for every traveler.

  • Montero: Located 49.9km from Santa Cruz, Montero is a lively city that attracts travelers year-round. The peak travel months are January and September to October, making it a great choice for family and business-themed experiences. Visitors will find an array of shopping options, including shopping centers and malls that cater to both locals and tourists alike. Montero's urban vibe, coupled with its convenient amenities, makes it an ideal spot for those looking to explore local culture while indulging in retail therapy.
  • La Guardia: Situated 20.9km from Santa Cruz, La Guardia is a charming city known for its outdoor and family-friendly atmosphere. With peak visitor numbers in September and December to January, this destination offers a refreshing escape for nature lovers. The local botanical garden is a must-visit, showcasing the region's diverse flora. Additionally, resorts in the area provide a perfect setting for relaxation and leisure, making La Guardia an excellent choice for families and nature enthusiasts seeking a delightful getaway.
  • Warnes: Just 30.6km from Santa Cruz, Warnes is another inviting city perfect for families and outdoor adventurers. Peak arrivals occur in September and from December to January, and visitors can enjoy the best of both worlds with its blend of urban and natural attractions. The city features shopping centers and malls, alongside resorts that cater to relaxation seekers. The nearby botanical garden serves as an enchanting backdrop for leisurely strolls, making Warnes a well-rounded destination for those looking to experience both city life and nature.

Things to do in Santa Cruz

Santa Cruz offers a vibrant mix of family-friendly and cultural activities perfect for tourists. Explore its bustling shopping centers and malls, enjoy live music, and savor delicious meals at local restaurants. Don't miss the chance to experience outdoor activities that showcase the city's beautiful surroundings. With a rich array of entertainment options, Santa Cruz promises a memorable vacation filled with unique experiences.

Shopping

For a vibrant shopping experience, visit Ventura Mall, which offers entertainment and family-friendly vibes. Don't miss La Recova Artisan Walk for local crafts. If you're up for a drive, check out Patio Design LifeStyle Center, known for its stylish atmosphere and diverse shopping options.

Recreation

At Ramon Tahuichi Aguilera Stadium in Santa Cruz, immerse yourself in the vibrant sports culture. Engage in recreational activities, watch thrilling matches, or take part in community fitness events, all while enjoying the energetic atmosphere that this iconic venue has to offer.

Adventure

Parque Nacional Amboró offers thrilling hiking trails through diverse ecosystems, where you can spot exotic wildlife and stunning waterfalls. For an adrenaline rush, try white-water rafting on the Río Pirai, navigating exciting rapids surrounded by breathtaking scenery. Experience the vibrant culture by exploring the lively markets and local cuisine.

Nightlife

Experience the vibrant nightlife in Santa Cruz by catching a film at Cine Center, where you can enjoy a mix of romance and family-friendly entertainment. For a taste of local culture, visit Casa Municipal de Cultura Raúl Otero Reiche, a theater showcasing captivating performances in a charming atmosphere.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Santa Cruz

For a budget-friendly trip to Santa Cruz, consider visiting in January, June, or August when prices are lower. Saturdays are the cheapest days to stay, while Tuesdays are the priciest. Use Expedia to compare room rates and explore package deals that combine hotels, flights, and activities for added savings. Look for free activities around the city and take advantage of local public transportation for affordable travel. Sorting options by price can help you find the best deals tailored to your budget and preferences.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay in Santa Cruz are January, June and August, where the prices are slightly lower. This is in comparison to February, September and December, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay in Santa Cruz is Saturday. The most expensive day to stay in Santa Cruz is Tuesday.
  • Find cheap hotels on Expedia: Utilize Expedia's search tool to narrow down your options based on your budget, preferred location, and the type of hotel you’re looking for. To find the best prices and deals, simply sort the price filter from lowest to highest.
  • Consider bundling your trip: You can save money by combining your hotel reservations in Santa Cruz with your flights and activities through an Expedia package deal.

Find the best attractions in Santa Cruz

Santa Cruz, Bolivia, is perfect for city-themed, family, and cultural vacations. Explore its stunning cathedrals, vibrant piazzas, and local landmarks that cater to travelers seeking cultural and outdoor experiences. Don't miss the beautiful Santa Cruz beach for relaxation and fun. For accommodations, consider the various motels in the Santa Cruz area to ensure a comfortable stay during your visit.

  • Plaza 24 de Septiembre: This vibrant square is the heart of Santa Cruz, offering a blend of local culture and city vibes. It's an ideal spot to relax, enjoy street performances, and savor traditional Bolivian snacks from nearby vendors.
  • San Lorenzo Cathedral: A stunning example of colonial architecture, this cathedral showcases exquisite art and deep cultural significance. Visitors can admire its beautiful façade and tranquil atmosphere, perfect for reflection and appreciation of local history.
  • Lomas de Arena Regional Park: Experience the natural beauty of Santa Cruz in this unique desert-like environment, featuring sandy hills and diverse wildlife. It's a perfect getaway for sunbathing, hiking, and enjoying the warm weather.

Best time to go to Santa Cruz

The best time to visit Santa Cruz can depend on the weather and when visitor numbers rise and fall. The hottest average temperature in Santa Cruz falls in October, when visitor numbers are slightly low and weather is mostly sunny with light rain. The coolest average temperature in Santa Cruz falls in June, visitor numbers are average and weather is mostly sunny with light rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January78.3°F (25.7°C)Light RainMostly SunnySlightly HighSlightly Low
February77.0°F (25.0°C)Light RainMostly CloudyAverageSlightly High
March76.5°F (24.7°C)Light RainMostly SunnyAverageAverage
April74.5°F (23.6°C)Light RainMostly SunnyAverageAverage
May70.2°F (21.2°C)Light RainMostly SunnySlightly LowAverage
June67.8°F (19.9°C)Light RainMostly SunnyAverageSlightly Low
July68.5°F (20.3°C)No RainMostly SunnySlightly HighAverage
August72.9°F (22.7°C)No RainSunnyAverageSlightly Low
September77.9°F (25.5°C)Light RainSunnySlightly HighSlightly High
October79.5°F (26.4°C)Light RainMostly SunnySlightly LowAverage
November79.3°F (26.3°C)Light RainMostly SunnyAverageAverage
December78.4°F (25.8°C)Light RainMostly SunnySlightly LowSlightly High

The nearest major airports for your trip to Santa Cruz

Traveling to Santa Cruz, Bolivia, is convenient with the main airport, Viru Viru International Airport (VVI), located 16.1km from the city. Nearby, you’ll find excellent 5-star accommodations such as the Marriott Santa Cruz de la Sierra and Radisson Hotel Santa Cruz, both situated 14.5km from the airport. The Novotel Santa Cruz De La Sierra is also a great option, located 17.7km away. These hotels offer easy access to the airport, ensuring a smooth transition for your travels. Whether you seek luxury or comfort, these options provide a perfect stay while exploring the vibrant city of Santa Cruz.

Frequently asked questions

What's the best place for a stay in Santa Cruz?
Ibis Santa Cruz DE LA Sierra is one of the top choices for your stay based on our traveler data. This hotel offers a restaurant and free parking. Other good choices for your visit include Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel and Marriott Santa Cruz de la Sierra Hotel. See all available top hotels, or vacation rentals in Santa Cruz.
What's the top vacation rental that Santa Cruz has to offer?
Casa Vida: Visitors give good reviews to this Santa Cruz vacation home rental, which is located in a rural location and has an outdoor pool, a patio, and a barbecue grill to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a full-sized fridge, a stovetop, and a microwave, so you can cook with friends or family. Kick off your shoes and enjoy yourself with a private yard and a selection of games. See all vacation rentals in Santa Cruz.
If I need to cancel my hotel reservation in Santa Cruz, will I receive a refund?
Yes! Most hotel reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If your reservation is non-refundable, you might still have the option to cancel and get a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Santa Cruz.
Where can I learn more about changing or cancelling my trip to Santa Cruz?
To find more details about picking new dates or cancelling your trip to Santa Cruz, head over to our customer service page.
What's the best budget-friendly accommodation in Santa Cruz?
Based on our traveler reviews, residencial francia - Hostel is a top choice for a less expensive stay. Other choices for your budget-friendly stay include Residencial Ikandire II and Nomad Hostel. View all budget hotels in Santa Cruz.
What's the best accommodation for a family trip to Santa Cruz?
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel is a hotel with 2 restaurants and free parking, and it's a top choice on Expedia for families. Other choices for your stay with the kids include Marriott Santa Cruz de la Sierra Hotel and Camino Real Hotel. Attractions like Santa Cruz Zoo and Play Land Amusement Park are also fun for kids of all ages. Find more child-friendly accommodations in Santa Cruz.
What is the top LGBTQ-friendly accommodation in Santa Cruz?
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia is a top LGBTQ-friendly hotel that features free breakfast and free WiFi. Hotel Pascana centro and Swissôtel Santa Cruz De La Sierra are other good choices for your trip. See all available hotels listed as LGBTQ-friendly in Santa Cruz.
What's the best pet-friendly hotel in Santa Cruz?
Casa Por Temporadas is a top dog-friendly guesthouse, and offers an outdoor pool along with in-room kitchens for its human guests. Other good options for you and your pet's trip include Ibis Santa Cruz DE LA Sierra and Hotel LP Equipetrol. See more pet-friendly hotel accommodations in Santa Cruz.
Where is the best place to stay close to Plaza 24 de Septiembre?
Adjacent to Plaza 24 de Septiembre, Nomad Hostel is one of the top choices for your stay based on our traveler data, and this property offers a restaurant and a bar. Other good options close by include Senses Centro and Cosmopolitano Hotel Boutique.
What about the best place to stay near Ventura Mall?
One of the top choices for your stay is Camino Real Hotel, located next to Ventura Mall, and this 4-star hotel offers 2 bars and a restaurant. Los Tajibos Hotel And Convention Center and Marriott Santa Cruz de la Sierra Hotel are two other good choices in the immediate area.
What's the best luxury accommodation in Santa Cruz?
Marriott Santa Cruz de la Sierra Hotel is a luxury hotel with a full-service spa and a rooftop terrace, and it's a popular choice for Expedia travelers looking for an elegant place to stay. Camino Real Hotel and Hampton by Hilton Santa Cruz/Equipetrol, Bolivia are other upscale choices for your vacation. Find more luxury hotels in Santa Cruz.
What are some accommodations with pools in Santa Cruz?
Yotau All Suites Hotel is a top hotel with 2 outdoor pools, a children's pool, and 2 restaurants. A couple of other options that offer an onsite pool include Gran Hotel Santa Cruz and Buganvillas Hotel Suites & Spa. View all hotels with pools in Santa Cruz.
What is the best spa hotel in Santa Cruz?
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel is a top spa hotel featuring a fitness center, a hair salon, and a bar. Enjoy a facial, body scrub, or hydrotherapy at Los Tajibos Club Spa. Other popular spa hotels in Santa Cruz include Marriott Santa Cruz de la Sierra Hotel and Camino Real Hotel. See all spa hotels in Santa Cruz.
What's the top hotel in Santa Cruz with an on-site water park or a water park nearby?
Gran Hotel Santa Cruz is a popular hotel featuring free water park access, an outdoor pool, and a restaurant. Check out all hotels with or near waterparks in Santa Cruz.
What's the best hotel for staying near Viru Viru International Airport (VVI)?
Sun Hotel is a popular 3.5-star hotel featuring free breakfast and a restaurant. It's located a short 1.3 mi (2.1 km) from Viru Viru Intl. Airport.
How is it to stay in Santa Cruz?
Visitors to Santa Cruz are sure to enjoy the shopping. Tourists can also enjoy the city's cafes, zoo, and cathedral. In Santa Cruz, there are 312 hotels and other accommodations to choose from. Find out more about Santa Cruz.
What should I do while I'm visiting Santa Cruz?
Cultural venues include Ethno-folkloric Museum, Cine Center, and Sacred Art Museum. Landmarks like San Lorenzo Cathedral, Plaza 24 de Septiembre, and Blacutt Square might be worth a visit. Natural beauty is on display at Arenal Park, Guembe Biocenter, and Lomas de Arena Regional Park. Check out what more to see and do in Expedia's Santa Cruz guide.
How should I get around Santa Cruz?
To see more of the larger area, ride aboard one of the trains from Santa Cruz de la Sierra Station. If you want to venture out around the area, you may want a rental car in Santa Cruz for your journey.
What's the weather like in Santa Cruz?
The hottest months are usually October and November with an average temp of 79°F, while the coldest months are June and July with an average of 70°F. Average annual precipitation for Santa Cruz is 48 inches.

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