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Check prices for these dates

Tonight
Jan 22 - Jan 23
Tomorrow
Jan 23 - Jan 24
This weekend
Jan 23 - Jan 25
Next weekend
Jan 30 - Feb 1

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Our top choices for Sanctuary hotels

Balcony view

Lovers Key Resort

Lovers Key Resort
3.0 star property
30.3 km from Sanctuary
8.8 out of 10, Excellent, (1,024 reviews)
"Wonderful place to relax and a good spot for exploring the coastal area. "
United States
Gerald L.
Lovers Key Resort
Exterior

Homewood Suites by Hilton - Fort Myers

Homewood Suites by Hilton - Fort Myers
3.0 star property
30.9 km from Sanctuary
9.2 out of 10, Wonderful, (1,002 reviews)
"Clean and tidy hotel, friendly staff and the breakfast is excellent. 4th time we have stayed here in last 15 months"
United Kingdom
Adam
The price is NT$6,092
NT$6,793 total
includes taxes & fees
Jan 31 - Feb 1
Homewood Suites by Hilton - Fort Myers
Bar (on property)

Doubletree by Hilton Fort Myers at Bell Tower Shops

Doubletree by Hilton Fort Myers at Bell Tower Shops
4.0 star property
30.8 km from Sanctuary
8.8 out of 10, Excellent, (1,000 reviews)
"Great stay "
United States
Brandon
The price is NT$5,132
NT$5,723 total
includes taxes & fees
Jan 28 - Jan 29
Doubletree by Hilton Fort Myers at Bell Tower Shops
Lobby lounge

Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral

Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral
3.0 star property
30.1 km from Sanctuary
8.6 out of 10, Excellent, (808 reviews)
"Good location "
United States
Lynn
The price is NT$3,667
NT$4,089 total
includes taxes & fees
Feb 1 - Feb 2
Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral
House | 2 bedrooms

Redfish Retreat - South End Pool Home

Redfish Retreat - South End Pool Home
2.0 star property
29 km from Sanctuary
Redfish Retreat - South End Pool Home
Terrace/patio

Hilton Garden Inn Ft Myers

Hilton Garden Inn Ft Myers
3.0 star property
29.5 km from Sanctuary
8.8 out of 10, Excellent, (1,003 reviews)
"Great stay"
United States
Erica
The price is NT$5,538
NT$6,175 total
includes taxes & fees
Jan 28 - Jan 29
Hilton Garden Inn Ft Myers
On the beach, white sand

GullWing Beach Resort

GullWing Beach Resort
3.5 star property
27.3 km from Sanctuary
9.4 out of 10, Exceptional, (932 reviews)
"The view of the beach was spectacular. "
United States
Carol
The price is NT$7,404
NT$19,590 total
includes taxes & fees
Jan 29 - Jan 30
GullWing Beach Resort
Superior King Room | Individually decorated, individually furnished, iron/ironing board

Flamingo Inn

Flamingo Inn
3.0 star property
26.9 km from Sanctuary
7.8 out of 10, Good, (986 reviews)
"Quiet, clean and updated room. Easy walk to the beach."
United States
KATHLEEN
The price is NT$4,046
NT$6,711 total
includes taxes & fees
Jan 25 - Jan 26
Flamingo Inn
Exterior

Candlewood Suites Fort Myers Sanibel Gateway by IHG

Candlewood Suites Fort Myers Sanibel Gateway by IHG
3.0 star property
25.4 km from Sanctuary
7.4 out of 10, Good, (1,002 reviews)
"Great place to stay."
United States
David
The price is NT$3,670
NT$4,093 total
includes taxes & fees
Feb 1 - Feb 2
Candlewood Suites Fort Myers Sanibel Gateway by IHG
Exterior

Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG
2.5 star property
23.1 km from Sanctuary
9.4 out of 10, Exceptional, (1,007 reviews)
"Clean room, quiet and very comfortable bed."
United Kingdom
Helen
The price is NT$5,089
NT$5,675 total
includes taxes & fees
Jan 25 - Jan 26
Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG
Lobby

Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway

Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway
3.0 star property
22.9 km from Sanctuary
8.4 out of 10, Very Good, (1,009 reviews)
"Clean room great breakfast staff very friendly and courteous. "
United States
Paula
The price is NT$4,914
NT$5,479 total
includes taxes & fees
Jan 28 - Jan 29
Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway
Exterior

TriLuxe Inn & Studios

TriLuxe Inn & Studios
2.0 star property
22.7 km from Sanctuary
8.2 out of 10, Very Good, (17 reviews)
"Everything was great, will definitely be coming back"
United States
Ruben
The price is NT$2,943
NT$4,305 total
includes taxes & fees
Jan 26 - Jan 27
TriLuxe Inn & Studios
Classic Studio | Living area

Summerwind Studios

Summerwind Studios
2.0 star property
22.6 km from Sanctuary
8.0 out of 10, Very Good, (11 reviews)
"Very clean and roomy. Quiet neighborhood. Loves the shower; so relaxing. Only complaint is that we could have used some drinking glasses. I would stay here again. "
United States
Micki
The price is NT$2,879
NT$4,234 total
includes taxes & fees
Jan 23 - Jan 24
Summerwind Studios
Grand Studio Suite, Kitchenette | Desk, laptop workspace, free WiFi, bed sheets

Lazy Cuckoo Inn

Lazy Cuckoo Inn
2.0 star property
22.1 km from Sanctuary
9.0 out of 10, Wonderful, (234 reviews)
"Very nice. Great for a short or longer term stay."
United States
Finley
The price is NT$2,466
NT$3,772 total
includes taxes & fees
Jan 25 - Jan 26
Lazy Cuckoo Inn
House, Accessible | 4 bedrooms

Riverfront Home w Private Dock Pool Beaches

Riverfront Home w Private Dock Pool Beaches
2.0 star property
26 km from Sanctuary
The price is NT$14,988
NT$32,382 total
includes taxes & fees
Feb 1 - Feb 2
Riverfront Home w Private Dock Pool Beaches
Floating Coconut Cottage Houseboat | Terrace/patio

Latitude 26 Waterfront Resort & Marina

Latitude 26 Waterfront Resort & Marina
3.0 star property
22 km from Sanctuary
8.6 out of 10, Excellent, (924 reviews)
"Staff was very helpful at check-in; room was clean. As a solo female traveler, I felt safe. "
United States
Kimberly
Latitude 26 Waterfront Resort & Marina
View from room

Pointe Estero Beach Resort

Pointe Estero Beach Resort
2.0 star property
27.3 km from Sanctuary
9.2 out of 10, Wonderful, (1,002 reviews)
"Nice place Clean rooms Friendly staff "
United States
SALMAN
The price is NT$9,294
NT$20,629 total
includes taxes & fees
Jan 23 - Jan 24
Pointe Estero Beach Resort
3 restaurants, breakfast, lunch, dinner served; Italian cuisine

Lani Kai Beachfront Resort

Lani Kai Beachfront Resort
3.5 star property
21.8 km from Sanctuary
9.0 out of 10, Wonderful, (1,144 reviews)
"The breakfast was good "
United States
Ileana
The price is NT$7,369
NT$8,921 total
includes taxes & fees
Jan 25 - Jan 26
Lani Kai Beachfront Resort
Balcony view

OYO Waterfront Hotel - Cape Coral/Fort Myers, FL

OYO Waterfront Hotel - Cape Coral/Fort Myers, FL
2.5 star property
25.2 km from Sanctuary
5.8 out of 10, (1,003 reviews)
"Beautiful place "
United States
Blaine
The price is NT$2,571
NT$3,089 total
includes taxes & fees
Jan 23 - Jan 24
OYO Waterfront Hotel - Cape Coral/Fort Myers, FL
In-room safe, desk, laptop workspace, blackout drapes

Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Holiday Inn Express Cape Coral-Fort Myers Area by IHG
2.5 star property
23.9 km from Sanctuary
9.2 out of 10, Wonderful, (1,179 reviews)
"Is great place to stay."
United States
Anastassia
The price is NT$4,520
NT$5,040 total
includes taxes & fees
Jan 25 - Jan 26
Holiday Inn Express Cape Coral-Fort Myers Area by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Sanctuary

Find the best Sanctuary areas and neighborhoods for the activities you enjoy most.
Fort Myers featuring a sandy beach
Photo by Sanibel Captiva Chamber of Commerce/Milissa Sprecher Photography
Open Photo by Sanibel Captiva Chamber of Commerce/Milissa Sprecher Photography

West End

While visiting West End, you might make a stop by sights like J. N. Ding Darling National Wildlife Refuge and Bowman's Beach.

Sanibel Historical Museum and Village showing heritage elements

Mid Island

While visiting Mid Island, you might make a stop by sights like Periwinkle Way and Sanibel Island Southern Beach.

J. N. Ding Darling National Wildlife Refuge which includes marine life and dangerous animals

East End

While visiting East End, you might make a stop by sights like Sanibel Island Northern Beach and Sanibel Island Lighthouse.

Periwinkle Way featuring cycling as well as an individual femail

Beachview Country Club Estates

If you're spending some time in Beachview Country Club Estates, Periwinkle Way and Sanibel Island Golf Club are top sights worth seeing.

Shell Harbor

Though Shell Harbor might not have many top sights, you can venture to the surrounding area to see attractions like Sanibel Moorings Botanical Gardens and Sanibel Sea School.

Top Sanctuary Hotel Reviews

Lani Kai Beachfront Resort

Lani Kai Beachfront Resort

10/10 Excellent
"The room was clean and the view of the beach, ocean and sunsets were great! Staff was polite and helpful. "
Elizabeth 3-night trip
Posted 3 days ago
Lani Kai Beachfront Resort

Frequently asked questions

What is Sanctuary like?
Travelers are sure to enjoy a stay in Sanibel's Sanctuary neighborhood. Consider a visit to J. N. Ding Darling National Wildlife Refuge as part of your Sanctuary travel plans.
How many hotels are there in the Sanctuary area?
With 11 Expedia hotels and other accommodations in Sanctuary to choose from, this is a good starting point for exploring the greater Sanibel area.
If I need to cancel my hotel reservation in Sanctuary, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable as long as you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of your check-in date. If your reservation is non-refundable, it might still be possible to cancel it and get a refund within a 24-hour period of booking. Enter your dates, click on "Search", then you can use the "fully refundable" filter to review top deals in Sanctuary.
Where can I learn more about changing or cancelling my trip to Sanctuary?
For more information about updating your trip to Sanctuary or cancelling it, click here.
What is there to do around this Sanibel neighborhood?
J. N. Ding Darling National Wildlife Refuge is an attraction you might want to check out while you're in Sanctuary. Castaways Marina and Blind Pass Beach are also worth a visit when you're out sightseeing in Sanibel.

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