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Our top choices for San Sebastiano hotels

Oriana Homèl Milano

Oriana Homèl Milano
Centro Storico, 0.1 km from San Sebastiano
10.0 out of 10, Exceptional, (39)
"Perfect stay!"
Australia
Martin
The price is NT$5,023
NT$6,227 total
includes taxes & fees
Dec 25 - Dec 26
Oriana Homèl Milano

Hotel Spadari Al Duomo

Hotel Spadari Al Duomo
4.0 star property
Centro Storico, 0.2 km from San Sebastiano
9.8 out of 10, Exceptional, (645)
"Best hotel in the best location with kind and attentive staff! Excellent breakfast. Comfortable bed. Bathroom (newly renovated) gorgeous! "
United States
Karen
The price is NT$10,976
NT$12,813 total
includes taxes & fees
Jan 12 - 2026/1/13
Hotel Spadari Al Duomo

AF Duomo - Milano Luxury Suites

AF Duomo - Milano Luxury Suites
Centro Storico, 0.3 km from San Sebastiano
9.8 out of 10, Exceptional, (28)
"Amazing view!!"
United States
Laura
The price is NT$20,425
NT$23,503 total
includes taxes & fees
Dec 26 - Dec 27
AF Duomo - Milano Luxury Suites

Heart Milan Apartments - Duomo Colonne

Heart Milan Apartments - Duomo Colonne
Centro Storico, 0.6 km from San Sebastiano
10.0 out of 10, Exceptional, (10)
"Clean, accessible to everything, well maintained place, good communication!"
United States
antonio
The price is NT$3,571
NT$4,630 total
includes taxes & fees
Jan 7 - 2026/1/8
Heart Milan Apartments - Duomo Colonne

notaMi - Cinque Vie Top Floor City Center

notaMi - Cinque Vie Top Floor City Center
0.4 km from San Sebastiano
9.6 out of 10, Exceptional, (15)
"My husband and my 7 years old daughter love this property. Clean, with everything you need for comfortable stay. Metro 8 min walking, near Duomo and other great places in Milan. Would stay there again."
United States
svitlana
The price is NT$3,332
NT$11,020 total
includes taxes & fees
Jan 4 - 2026/1/5
notaMi - Cinque Vie Top Floor City Center

Casa Brivio

Casa Brivio
Centro Storico, 0.4 km from San Sebastiano
9.6 out of 10, Exceptional, (34)
"Memorable stay."
United States
Nabeel
Casa Brivio

Speronari Suites

Speronari Suites
Centro Storico, 0.2 km from San Sebastiano
9.4 out of 10, Exceptional, (204)
"Great location."
United States
Bruce
The price is NT$9,535
NT$11,191 total
includes taxes & fees
Dec 21 - Dec 22
Speronari Suites

Brera Apartments in City Center

Brera Apartments in City Center
Centro Storico, 0.2 km from San Sebastiano
9.2 out of 10, Wonderful, (29)
"We really enjoyed our stay. It was in a great location with so many restaurants and shopping nearby along with historical sites."
United States
Leann
The price is NT$4,115
NT$7,818 total
includes taxes & fees
Jan 6 - 2026/1/7
Brera Apartments in City Center

Luxury Suite Milano Duomo

Luxury Suite Milano Duomo
Centro Storico, 0.3 km from San Sebastiano
9.4 out of 10, Exceptional, (231)
"Absolutely perfect location! Very spacious and beautiful room. Bed was very comfortable and the shower was wonderful! Extremely helpful and accommodating staff! We highly recommend to anyone."
United States
Karin
The price is NT$8,042
NT$9,549 total
includes taxes & fees
Jan 15 - 2026/1/16
Luxury Suite Milano Duomo

Prestige Boutique Homes Aparthotel Piazza Duomo View

Prestige Boutique Homes Aparthotel Piazza Duomo View
Centro Storico, 0.2 km from San Sebastiano
9.4 out of 10, Exceptional, (46)
"Wonderful stay! The room was perfect and the view of the duomo was beautiful! The staff was outstanding and welcoming. Highly recommend!"
United States
Robert
The price is NT$7,845
NT$14,195 total
includes taxes & fees
Dec 24 - Dec 25
Prestige Boutique Homes Aparthotel Piazza Duomo View

Ostello Bello Milano Duomo

Ostello Bello Milano Duomo
0.4 km from San Sebastiano
9.4 out of 10, Exceptional, (250)
"Everything was perfect. Awesome location. Friendly staff, would definitely stay again. "
United States
Youbi
The price is NT$3,287
NT$3,838 total
includes taxes & fees
Dec 22 - Dec 23
Ostello Bello Milano Duomo

Matilde Boutique Hotel, WorldHotels Elite

Matilde Boutique Hotel, WorldHotels Elite
4.0 star property
Centro Storico, 0.2 km from San Sebastiano
9.2 out of 10, Wonderful, (143)
"Great room, nice staff and breakfast. Concierge team was wonderful "
United States
Karrie Ellen
The price is NT$22,679
NT$25,686 total
includes taxes & fees
Dec 31 - 2026/1/1
Matilde Boutique Hotel, WorldHotels Elite

Room Mate Collection Giulia, Milan

Room Mate Collection Giulia, Milan
4.0 star property
Centro Storico, 0.4 km from San Sebastiano
9.6 out of 10, Exceptional, (1001)
"Excellent stay from start to finish ."
United States
Sergey
The price is NT$10,919
NT$12,750 total
includes taxes & fees
Dec 24 - Dec 25
Room Mate Collection Giulia, Milan

Park Hyatt Milano

Park Hyatt Milano
5.0 star property
Scala, 0.5 km from San Sebastiano
9.6 out of 10, Exceptional, (285)
"Great location"
United States
Lisa
The price is NT$42,538
NT$47,531 total
includes taxes & fees
Dec 22 - Dec 23
Park Hyatt Milano

The Square Milano Duomo - Preferred Hotels & Resorts

The Square Milano Duomo - Preferred Hotels & Resorts
4.0 star property
Centro Storico, 0.3 km from San Sebastiano
9.2 out of 10, Wonderful, (1000)
"Very nice hotel, nice rooms, great friendly staff, very nice location."
United States
Reem
The price is NT$11,093
NT$12,942 total
includes taxes & fees
Dec 21 - Dec 22
The Square Milano Duomo - Preferred Hotels & Resorts

Palazzo Touring Club Milan, A Radisson Collection Hotel

Palazzo Touring Club Milan, A Radisson Collection Hotel
5.0 star property
Centro Storico, 0.4 km from San Sebastiano
9.4 out of 10, Exceptional, (190)
"Beautiful Hotrel and great Location! Breakfast was good and the room great! "
United States
Giovanna
The price is NT$13,002
NT$15,042 total
includes taxes & fees
Dec 21 - Dec 22
Palazzo Touring Club Milan, A Radisson Collection Hotel

Milan Retreats Duomo

Milan Retreats Duomo
Centro Storico, 0.3 km from San Sebastiano
9.2 out of 10, Wonderful, (690)
"Great place and great apartment. I’ll come again "
United States
Mohammed
The price is NT$1,799
NT$4,455 total
includes taxes & fees
Dec 21 - Dec 22
Milan Retreats Duomo

Palazzo Cordusio Gran Meliá – The Leading Hotels of the World

Palazzo Cordusio Gran Meliá – The Leading Hotels of the World
5.0 star property
Centro Storico, 0.4 km from San Sebastiano
9.4 out of 10, Exceptional, (43)
"The room was extremely nice and the staff was kind"
United States
Roman
The price is NT$27,115
NT$30,565 total
includes taxes & fees
Dec 21 - Dec 22
Palazzo Cordusio Gran Meliá – The Leading Hotels of the World

Heart Milan Apartments - San Sepolcro Duomo

Heart Milan Apartments - San Sepolcro Duomo
Centro Storico, < 0.1 km from San Sebastiano
9.2 out of 10, Wonderful, (510)
"Beautiful place, amazing location. "
United States
Andre
The price is NT$4,385
NT$5,525 total
includes taxes & fees
Dec 24 - Dec 25
Heart Milan Apartments - San Sepolcro Duomo

ODSweet Duomo Milano Hotel

ODSweet Duomo Milano Hotel
4.0 star property
Centro Storico, 0.2 km from San Sebastiano
9.2 out of 10, Wonderful, (167)
"Great location with a nice rooftop. Great room and great staff. I recommend it. "
United States
VICTOR
The price is NT$12,275
NT$14,242 total
includes taxes & fees
Jan 4 - 2026/1/5
ODSweet Duomo Milano Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top San Sebastiano Hotel Reviews

Hotels near other San Sebastiano attractions

Frequently asked questions

What's the area like around San Sebastiano?
San Sebastiano is located in a historic area of Milan known for its stunning cathedral and top museums. If you're looking for a convenient place to stay, check out the 1290 hotels and other accommodations you'll find within a mile.
What's the best place to stay near San Sebastiano?
Adjacent to San Sebastiano, Hotel Dei Cavalieri Milano Duomo is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and a bar. Other good options within a short distance include The Square Milano Duomo - Preferred Hotels & Resorts and Hotel Brunelleschi.
How many hotels are there close to San Sebastiano?
Expedia has 1290 hotels and other accommodations within a mile from San Sebastiano.
If I need to cancel the hotel reservation for my stay near San Sebastiano, will I receive a refund?
Yes, you'll find most room reservations are refundable if you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If your reservation is non-refundable, it might still be possible to cancel it and receive a refund within 24 hours of your booking. Add your dates and click on "Search", then use the "fully refundable" filter to get the best options available near San Sebastiano.
Where can I learn more about changing or cancelling my trip in the area near San Sebastiano?
To access more information about picking new dates or cancelling your stay near San Sebastiano, head over to our customer service page.
What can I see and do near San Sebastiano?
Museo del Novecento, Castello Sforzesco, and Pinacoteca di Brera feature captivating exhibits. Sights like Cathedral of Milan, Biblioteca Ambrosiana, and Royal Palace of Milan are must-sees while exploring the area. You can check out the local talent at Teatro alla Scala, Teatro Dal Verme, and Teatro Manzoni.
How can I get to San Sebastiano?
With so many choices for transportation, seeing all of the area near San Sebastiano is simple. You can access metro transit at Duomo Station, Via Orefici P.za Cordusio Tram Stop, and Cordusio M1 Tram Stop. If you're taking a train into town, Milan Cadorna Nord Station and Milan (XNC-Cadorna Train Station) are the closest stations to Milan Centre.