Find hotels near San Sebastiano, Milan from NT$3,873

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Dec 22 - Dec 23
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Dec 23 - Dec 24
This weekend
Dec 26 - Dec 28
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Jan 2 - Jan 4

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Our top choices for San Sebastiano hotels

Exterior
Oriana Homèl Milano

Oriana Homèl Milano

Oriana Homèl Milano
Centro Storico, 0.1 km from San Sebastiano
10.0 out of 10, Exceptional, (39)
"Perfect stay!"
Australia
Martin
The price is NT$4,690
NT$5,861 total
includes taxes & fees
Dec 25 - Dec 26
Oriana Homèl Milano
Elite Apartment, 2 Bedrooms, Balcony (Piazza Erculea 5) | Balcony
Heart Milan Apartments Duomo Missori

Heart Milan Apartments Duomo Missori

Heart Milan Apartments Duomo Missori
Centro Storico, 0.2 km from San Sebastiano
10.0 out of 10, Exceptional, (11)
"Great property and stay! The property was super communicative and met us at the apartment to give us the keys! The apartment was large with plenty of space, an awesome balcony, and comfy beds. The location was perfect - close to the Duomo and transpiration options (metro and tram stops) "
United States
Alison
The price is NT$5,974
NT$7,274 total
includes taxes & fees
Jan 7 - 2026/1/8
Heart Milan Apartments Duomo Missori
Lounge
Hotel Spadari Al Duomo

Hotel Spadari Al Duomo

Hotel Spadari Al Duomo
4.0 star property
Centro Storico, 0.2 km from San Sebastiano
9.8 out of 10, Exceptional, (645)
"Best hotel in the best location with kind and attentive staff! Excellent breakfast. Comfortable bed. Bathroom (newly renovated) gorgeous! "
United States
Karen
The price is NT$10,976
NT$12,813 total
includes taxes & fees
Jan 12 - 2026/1/13
Hotel Spadari Al Duomo
Property entrance
Hotel Gran Duca Di York

Hotel Gran Duca Di York

Hotel Gran Duca Di York
3.0 star property
Centro Storico, 0.2 km from San Sebastiano
9.6 out of 10, Exceptional, (548)
"Great location, quiet and friendly staff!"
United States
Anette
The price is NT$6,531
NT$7,731 total
includes taxes & fees
Jan 18 - 2026/1/19
Hotel Gran Duca Di York
City Apartment (Via De Amici 9) | Premium bedding, down comforters, in-room safe, individually decorated
Heart Milan Apartments - Duomo Colonne

Heart Milan Apartments - Duomo Colonne

Heart Milan Apartments - Duomo Colonne
Centro Storico, 0.6 km from San Sebastiano
10.0 out of 10, Exceptional, (10)
"Clean, accessible to everything, well maintained place, good communication!"
United States
antonio
The price is NT$3,568
NT$4,627 total
includes taxes & fees
Jan 7 - 2026/1/8
Heart Milan Apartments - Duomo Colonne
Royal Luxury Suite Litta, Duomo View | Premium bedding, down comforters, pillowtop beds, minibar
AF Duomo - Milano Luxury Suites

AF Duomo - Milano Luxury Suites

AF Duomo - Milano Luxury Suites
Centro Storico, 0.3 km from San Sebastiano
9.8 out of 10, Exceptional, (28)
"Amazing view!!"
United States
Laura
The price is NT$20,411
NT$23,487 total
includes taxes & fees
Dec 26 - Dec 27
AF Duomo - Milano Luxury Suites
Royal Apartment, 3 Bedrooms, City View (Via Santa Maria Valle 7) | Terrace/patio
Heart Milan Apartments - San Sepolcro Duomo

Heart Milan Apartments - San Sepolcro Duomo

Heart Milan Apartments - San Sepolcro Duomo
Centro Storico, < 0.1 km from San Sebastiano
9.2 out of 10, Wonderful, (510)
"Beautiful place, amazing location. "
United States
Andre
The price is NT$4,385
NT$5,525 total
includes taxes & fees
Dec 24 - Dec 25
Heart Milan Apartments - San Sepolcro Duomo
Front of property - evening/night
Room Mate Collection Giulia, Milan

Room Mate Collection Giulia, Milan

Room Mate Collection Giulia, Milan
4.0 star property
Centro Storico, 0.4 km from San Sebastiano
9.6 out of 10, Exceptional, (1002)
"Excellent stay from start to finish ."
United States
Sergey
The price is NT$11,255
NT$13,120 total
includes taxes & fees
Dec 24 - Dec 25
Room Mate Collection Giulia, Milan
Down comforters, minibar, in-room safe, blackout drapes
Speronari Suites

Speronari Suites

Speronari Suites
Centro Storico, 0.2 km from San Sebastiano
9.4 out of 10, Exceptional, (204)
"Great location."
United States
Bruce
The price is NT$10,442
NT$12,189 total
includes taxes & fees
Jan 11 - 2026/1/12
Speronari Suites
Deluxe Condo | Private kitchen | Full-size fridge, microwave, oven, stovetop
notaMi - Cinque Vie Top Floor City Center

notaMi - Cinque Vie Top Floor City Center

notaMi - Cinque Vie Top Floor City Center
0.4 km from San Sebastiano
9.6 out of 10, Exceptional, (15)
"My husband and my 7 years old daughter love this property. Clean, with everything you need for comfortable stay. Metro 8 min walking, near Duomo and other great places in Milan. Would stay there again."
United States
svitlana
The price is NT$3,332
NT$11,020 total
includes taxes & fees
Jan 6 - 2026/1/7
notaMi - Cinque Vie Top Floor City Center
Lobby lounge
Park Hyatt Milano

Park Hyatt Milano

Park Hyatt Milano
5.0 star property
Scala, 0.5 km from San Sebastiano
9.6 out of 10, Exceptional, (285)
"Great location"
United States
Lisa
The price is NT$42,538
NT$47,531 total
includes taxes & fees
Dec 25 - Dec 26
Park Hyatt Milano
Reception
Casa Brivio

Casa Brivio

Casa Brivio
Centro Storico, 0.4 km from San Sebastiano
9.6 out of 10, Exceptional, (34)
"Memorable stay."
United States
Nabeel
Casa Brivio
Presidential Suite | Down comforters, minibar, in-room safe, individually decorated
Palazzo Touring Club Milan, A Radisson Collection Hotel

Palazzo Touring Club Milan, A Radisson Collection Hotel

Palazzo Touring Club Milan, A Radisson Collection Hotel
5.0 star property
Centro Storico, 0.4 km from San Sebastiano
9.4 out of 10, Exceptional, (190)
"Beautiful Hotrel and great Location! Breakfast was good and the room great! "
United States
Giovanna
The price is NT$13,002
NT$15,042 total
includes taxes & fees
Dec 23 - Dec 24
Palazzo Touring Club Milan, A Radisson Collection Hotel
Interior entrance
Brera Apartments in City Center

Brera Apartments in City Center

Brera Apartments in City Center
Centro Storico, 0.2 km from San Sebastiano
9.2 out of 10, Wonderful, (29)
"We really enjoyed our stay. It was in a great location with so many restaurants and shopping nearby along with historical sites."
United States
Leann
The price is NT$4,112
NT$7,813 total
includes taxes & fees
Jan 6 - 2026/1/7
Brera Apartments in City Center
Exterior
Ostello Bello Milano Duomo

Ostello Bello Milano Duomo

Ostello Bello Milano Duomo
0.4 km from San Sebastiano
9.4 out of 10, Exceptional, (250)
"Everything was perfect. Awesome location. Friendly staff, would definitely stay again. "
United States
Youbi
The price is NT$3,319
NT$3,873 total
includes taxes & fees
Dec 23 - Dec 24
Ostello Bello Milano Duomo
Breakfast and dinner served, international cuisine
The Square Milano Duomo - Preferred Hotels & Resorts

The Square Milano Duomo - Preferred Hotels & Resorts

The Square Milano Duomo - Preferred Hotels & Resorts
4.0 star property
Centro Storico, 0.3 km from San Sebastiano
9.2 out of 10, Wonderful, (1003)
"Very nice hotel, nice rooms, great friendly staff, very nice location."
United States
Reem
The price is NT$11,093
NT$12,942 total
includes taxes & fees
Dec 23 - Dec 24
The Square Milano Duomo - Preferred Hotels & Resorts
Terrace/patio
Milan Retreats Duomo

Milan Retreats Duomo

Milan Retreats Duomo
Centro Storico, 0.3 km from San Sebastiano
9.2 out of 10, Wonderful, (691)
"Great place and great apartment. I’ll come again "
United States
Mohammed
The price is NT$2,607
NT$5,344 total
includes taxes & fees
Dec 23 - Dec 24
Milan Retreats Duomo
Free daily buffet breakfast
Matilde Boutique Hotel, WorldHotels Elite

Matilde Boutique Hotel, WorldHotels Elite

Matilde Boutique Hotel, WorldHotels Elite
4.0 star property
Centro Storico, 0.2 km from San Sebastiano
9.2 out of 10, Wonderful, (143)
"Great room, nice staff and breakfast. Concierge team was wonderful "
United States
Karrie Ellen
The price is NT$22,679
NT$25,686 total
includes taxes & fees
Dec 31 - 2026/1/1
Matilde Boutique Hotel, WorldHotels Elite
Superior Double Room, Balcony, City View | Terrace/patio
Luxury Suite Milano Duomo

Luxury Suite Milano Duomo

Luxury Suite Milano Duomo
Centro Storico, 0.3 km from San Sebastiano
9.4 out of 10, Exceptional, (231)
"Beds were very comfortable, location was awesome "
United States
Nadia
The price is NT$7,731
NT$9,206 total
includes taxes & fees
Jan 15 - 2026/1/16
Luxury Suite Milano Duomo
Exterior
Santa Marta Suites

Santa Marta Suites

Santa Marta Suites
4.0 star property
Centro Storico, 0.2 km from San Sebastiano
9.2 out of 10, Wonderful, (157)
"Super location!"
United States
Ivan
Santa Marta Suites
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top San Sebastiano Hotel Reviews

Room Mate Collection Giulia, Milan

Room Mate Collection Giulia, Milan

10/10 Excellent
"Best hotel ever Great location "
Naz 3-night trip
Posted 3 days ago
Room Mate Collection Giulia, Milan

Hotels near other San Sebastiano attractions

Biblioteca Ambrosiana

One of Europe’s first public libraries is home to Leonardo da Vinci’s Codex Atlanticus, which is housed alongside a huge book and art collection.
See properties

Via Torino

During your visit to Milan, you can search for that perfect souvenir at Via Torino. Make time to visit the area's stunning cathedral, or simply enjoy its charming cafes.
See properties

Frequently asked questions

What's the area like around San Sebastiano?
San Sebastiano is located in a historic area of Milan known for its stunning cathedral and top museums. If you're looking for a convenient place to stay, check out the 1296 hotels and other accommodations you'll find within a mile.
What's the best place to stay near San Sebastiano?
Adjacent to San Sebastiano, Hotel Dei Cavalieri Milano Duomo is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and a bar. Other good options within a short distance include Rosa Grand Milano - Starhotels Collezione and The Square Milano Duomo - Preferred Hotels & Resorts.
How many hotels are there close to San Sebastiano?
Expedia has 1296 hotels and other accommodations within a mile from San Sebastiano.
If I need to cancel the hotel reservation for my stay near San Sebastiano, will I receive a refund?
Yes, you'll find most room reservations are refundable if you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If your reservation is non-refundable, it might still be possible to cancel it and receive a refund within 24 hours of your booking. Add your dates and click on "Search", then use the "fully refundable" filter to get the best options available near San Sebastiano.
Where can I learn more about changing or cancelling my trip in the area near San Sebastiano?
To access more information about picking new dates or cancelling your stay near San Sebastiano, head over to our customer service page.
What can I see and do near San Sebastiano?
Museo del Novecento, Castello Sforzesco, and Pinacoteca di Brera feature captivating exhibits. Sights like Cathedral of Milan, Biblioteca Ambrosiana, and Royal Palace of Milan are must-sees while exploring the area. You can check out the local talent at Teatro alla Scala, Teatro Dal Verme, and Teatro San Babila.
How can I get to San Sebastiano?
With so many choices for transportation, seeing all of the area near San Sebastiano is simple. You can access metro transit at Duomo Station, Via Orefici P.za Cordusio Tram Stop, and Cordusio M1 Tram Stop. If you're taking a train into town, Milan Cadorna Nord Station and Milan (XNC-Cadorna Train Station) are the closest stations to Milan Centre.