Photo by Anthony Hilario

Find Resorts & Hotels with Spas in San Luis Obispo Wine Country, CA
- Change your mindBook hotels with free cancellation
- Be pickySearch almost a million properties worldwide
Check availability on San Luis Obispo Wine Country Resorts & Hotels with Spas
Our top choices for San Luis Obispo Wine Country hotels with a spa

9.2 out of 10, Wonderful, (1,423 reviews)
cleanliness Unwind at a unique spa retreat with six treatment rooms for aromatherapy, body scrubs, and massages in scenic comfort.
The price is NT$4,740
NT$6,463 total
includes taxes & fees
Apr 14 - Apr 15

9.6 out of 10, Exceptional, (1,000 reviews)
cleanliness Revitalizing seaside escape with private indoor hot tubs and spa services offers a wellness retreat just steps from the beach.
The price is NT$6,556
NT$7,376 total
includes taxes & fees
Apr 19 - Apr 20

9.2 out of 10, Wonderful, (477 reviews)
cleanliness Tranquil urban retreat with steam room, rooftop garden, and holistic treatments for a restorative wellness escape.
The price is NT$9,480
NT$11,863 total
includes taxes & fees
Apr 19 - Apr 20

9.6 out of 10, Exceptional, (596 reviews)
cleanliness Savor serenity at this luxury hotel with a full-service spa offering daily treatments and couples' massage rooms in San Luis Obispo.
The price is NT$13,427
NT$15,240 total
includes taxes & fees
Apr 20 - Apr 21

10.0 out of 10, Exceptional, (15 reviews)
The price is NT$6,316
NT$7,232 total
includes taxes & fees
Apr 13 - Apr 14

9.8 out of 10, Exceptional, (217 reviews)
cleanliness Relax in a beachside inn with private hot tubs, garden views, and rejuvenating couples massages.
The price is NT$5,313
NT$5,977 total
includes taxes & fees
Apr 13 - Apr 14

9.6 out of 10, Exceptional, (1,014 reviews)
cleanliness Revitalize mind and body at this charming hotel with therapeutic spa services and a bubbling hot tub.
The price is NT$5,190
NT$5,901 total
includes taxes & fees
Apr 13 - Apr 14

10.0 out of 10, Exceptional, (79 reviews)
cleanliness Vineyard escape at this tranquil hotel with Swedish massages, deep-tissue treatments, and on-site winery for a restorative getaway.
The price is NT$11,706
NT$14,112 total
includes taxes & fees
Apr 13 - Apr 14
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top San Luis Obispo Wine Country Hotel Reviews

Madonna Inn
8/10 Good
Explore a world of travel with Expedia
- Pet-Friendly Hotels in Avila Beach
- Hotels with a Pool in San Luis Obispo
- Hotels near Avila Beach Golf Resort
- Luxury Hotels in Avila Beach
- Hotels near Fremont Theater
- Beach Hotels in Downtown San Luis Obispo
- Best Western Hotels in San Luis Obispo
- Cheap Hotels in Pismo Beach
- Gay friendly Hotels in San Luis Obispo
- Winery Hotels in San Luis Obispo
- Family Hotels in Los Osos
- Cheap Hotels in San Luis Obispo
- Gay friendly Hotels in Pismo Beach
- Hotel Wedding Venues Hotels in Pismo Beach
- Beach Hotels in Avila Beach
- Family Hotels in Pismo Beach
- Green Hotels in San Luis Obispo
- Family Hotels in San Luis Obispo
- Hotels with Bars in Shell Beach
- Resorts & Hotels with Spas in Shell Beach
- Hotels with Hot Tubs in Avila Beach
- Pet-Friendly Hotels in MoJo
- Guest Houses in San Luis Obispo County
- 5 Star Hotels in San Luis Obispo
- Luxury Hotels in San Luis Obispo
- Hotels near French Hospital Medical Center
- Shopping Hotels in Avila Beach
- Resorts & Hotels with Spas in San Luis Obispo
- Romantic Hotels in Grover Beach
- Luxury Hotels in Pismo Beach
- Boutique Hotels in Pismo Beach
- Pacifica Hotels in San Luis Obispo
- Winery Hotels in Pismo Beach
- Resorts & Hotels with Spas in Los Osos
- Pet-Friendly Hotels in Pismo Beach
- Boutique Hotels in San Luis Obispo
- Casino Hotels in Pismo Beach
- Hotels near Mission San Luis Obispo de Tolosa
- 4 Star Hotels in San Luis Obispo
- Hotels near San Luis Obispo County Regional
- Flights from Charlotte (CLT) to San Luis Obispo (SBP)
- Flights from Kearney (EAR) to San Luis Obispo (SBP)
- Flights from Naples (NAP) to San Luis Obispo (SBP)
- Flights from San Luis Obispo
- Flights from North Bend (OTH) to San Luis Obispo (SBP)
- Flights from Flagstaff (FLG) to San Luis Obispo (SBP)
- Flights from Vienna (VIE) to San Luis Obispo (SBP)
- Flights from Montgomery (MGM) to San Luis Obispo (SBP)
- Flights from Sochi (AER) to San Luis Obispo (SBP)
- Flights from London (LGW) to San Luis Obispo (SBP)
- Flights to San Luis Obispo
- Flights from Fort Wayne (FWA) to San Luis Obispo (SBP)
- Flights from Guangzhou (CAN) to San Luis Obispo (SBP)
- Flights from Lübeck (LBC) to San Luis Obispo (SBP)
- Flights from Merced (MCE) to San Luis Obispo (SBP)
- Flights from Norfolk (ORF) to San Luis Obispo (SBP)
- Flights from Ashland (ASX) to San Luis Obispo (SBP)
- Flights from Florence (FLR) to San Luis Obispo (SBP)
- Flights from Des Moines (DSM) to San Luis Obispo (SBP)
- Flights from Santa Maria (SMX) to San Luis Obispo (SBP)
- Flights from Vernal (VEL) to San Luis Obispo (SBP)
- Flights from Indianapolis (IND) to San Luis Obispo (SBP)
- Flights from Cozumel (CZM) to San Luis Obispo (SBP)
- Flights from Harrisburg (MDT) to San Luis Obispo (SBP)
- Flights from Chico (CIC) to San Luis Obispo (SBP)
- Flights from Zacatecas (ZCL) to San Luis Obispo (SBP)
- Flights from Curitiba (CWB) to San Luis Obispo (SBP)
- Flights from Madrid (MAD) to San Luis Obispo (SBP)
- Flights from Key West (EYW) to San Luis Obispo (SBP)
- Flights from Lubbock (LBB) to San Luis Obispo (SBP)
- Flights from Blacksburg (BCB) to San Luis Obispo (SBP)
- Flights from San Francisco (SFO) to San Luis Obispo (SBP)
- Flights from Casper (CPR) to San Luis Obispo (SBP)
- Flights from Nice (NCE) to San Luis Obispo (SBP)
- Flights from Santo Domingo (SDQ) to San Luis Obispo (SBP)
- Flights from Concord (CCR) to San Luis Obispo (SBP)
- Flights from Hayward (HWD) to San Luis Obispo (SBP)
- Flights from Billund (BLL) to San Luis Obispo (SBP)
- Flights from Corvallis (CVO) to San Luis Obispo (SBP)
- Flights from Washington (IAD) to San Luis Obispo (SBP)
- Flights from Kalispell (FCA) to San Luis Obispo (SBP)
- Flights from Peoria (PIA) to San Luis Obispo (SBP)
- Flights from Springfield (SGF) to San Luis Obispo (SBP)
- Budget Rental Cars in San Luis Obispo County Regional
- Thrifty Car Rental Rental Cars in San Luis Obispo County Regional
- Budget Rental Cars in Avila Beach
- Avis Rental Cars in San Luis Obispo County Regional
- Alamo Rent A Car Rental Cars in San Luis Obispo
- Rental cars San Luis Obispo County Regional airport
- Enterprise Rental Cars in San Luis Obispo County Regional































