Find hotels in Downtown South San Francisco, San Francisco
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Our top choices for Downtown South San Francisco hotels
La Quinta Inn & Suites by Wyndham San Francisco Airport N
La Quinta Inn & Suites by Wyndham San Francisco Airport NDowntown South San Francisco
8.0 out of 10, Very Good, (2006)
"Clean room, staff were friendly, breakfast was good, parking was good, overall we're satisfied!"
Edna
The price is NT$3,190
NT$3,748 total
includes taxes & fees
Jan 5 - 2026/1/6
8.8 out of 10, Excellent, (972)
"Very clean room, friendly staff and secure parking."
Christopher
The price is NT$3,122
NT$3,662 total
includes taxes & fees
Dec 26 - Dec 27
7.4 out of 10, Good, (15)
"Own bedroom was quiet and tidy, shared bathroom clean and tidy, good communication "
Kasey
The price is NT$1,892
NT$4,603 total
includes taxes & fees
Dec 22 - Dec 23
7.8 out of 10, Good, (1000)
"Excellent property!!! I would definitely recommend!!! Great stay!!! "
David
The Westin San Francisco Airport
The Westin San Francisco Airport6.8 km from Downtown South San Francisco
8.8 out of 10, Excellent, (2024)
"Comfortable room, welcome glass of wine, easy shuttle to and from airport, friendly staff."
Carole
The price is NT$3,246
NT$4,654 total
includes taxes & fees
Dec 26 - Dec 27
Hotel Riu Plaza Fisherman's Wharf
Hotel Riu Plaza Fisherman's Wharf16.7 km from Downtown South San Francisco
9.0 out of 10, Wonderful, (7203)
"Great stay"
Isaac
The price is NT$3,390
NT$5,289 total
includes taxes & fees
Jan 5 - 2026/1/6
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Downtown South San Francisco
Find the best Downtown South San Francisco areas and neighborhoods for the activities you enjoy most.
Union Square
Major tourist destination in downtown San Francisco, Union Square boasts shopping, hotels, and theaters. Explore department stores, boutiques, and galleries, or catch a performance at various theaters. Enjoy the Dewey Monument and stunning views from nearby hotels. Easily accessible via cable car lines, buses, and subway systems.
Downtown San Francisco
Serving as San Francisco's central business district, this area boasts Northern California's two tallest buildings, the Salesforce Tower and Transamerica Pyramid. Explore shopping malls like the Embarcadero Center and enjoy parks such as Sue Biermann Park, all easily accessible via Muni bus and rail lines.
Fisherman's Wharf
Discover Pier 39, Ghirardelli Square, and the San Francisco Maritime National Historical Park in this bustling tourist hotspot. Savor seafood at family-owned restaurants and explore the sea lion colony, while enjoying convenient cable car access.
South of Market
From baseball games to top-notch art exhibits, find endless entertainment in one of San Francisco’s fastest-growing neighborhoods.
Nob Hill
Luxury hotels, historic mansions, and Michelin-starred restaurants abound in this upscale area. Explore Union Square shopping district, Grace Cathedral, and the SF Masonic Auditorium for a taste of culture and history.
Top Downtown South San Francisco Hotel Reviews
DoubleTree by Hilton Hotel Berkeley Marina
10/10 Excellent
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