Find Business Hotels in Perryville, MO
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Our top choices for Perryville business-friendly hotels
Holiday Inn Express & Suites Perryville by IHG
Holiday Inn Express & Suites Perryville by IHGPerryville
9.2 out of 10, Wonderful, (544)
"lean, updated rooms, friendly staff and great breakfast."
Linda
The price is NT$2,860
NT$3,275 total
includes taxes & fees
Jan 1 - 2026/1/2
8.4 out of 10, Very Good, (943)
"Always a great stay"
Steven
The price is NT$2,084
NT$2,386 total
includes taxes & fees
Jan 11 - 2026/1/12
6.8 out of 10, (416)
"Was a nice place."
Lesliee
The price is NT$1,950
NT$2,233 total
includes taxes & fees
Jan 1 - 2026/1/2
9.6 out of 10, Exceptional, (1004)
"Breakfast was great- staff was welcoming. Will stay there again."
Laura
The price is NT$2,609
NT$2,758 total
includes taxes & fees
Dec 30 - Dec 31
Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
Holiday Inn Express & Suites Murphysboro - Carbondale by IHGMurphysboro
9.4 out of 10, Exceptional, (513)
"Room was clean and amenities are fantastic. My family will certainly make this our top hotel choice in the area."
Christian
The price is NT$3,049
NT$3,384 total
includes taxes & fees
Jan 2 - 2026/1/3
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape GirardeauJackson
8.8 out of 10, Excellent, (679)
"Great place "
GUY
The price is NT$2,645
NT$2,863 total
includes taxes & fees
Jan 7 - 2026/1/8
8.6 out of 10, Excellent, (351)
"The room was clean and the staff were friendly. "
RODNEY
The price is NT$2,479
NT$2,751 total
includes taxes & fees
Jan 4 - 2026/1/5
Microtel Inn & Suites by Wyndham Sainte Genevieve
Microtel Inn & Suites by Wyndham Sainte GenevieveSte Genevieve
8.8 out of 10, Excellent, (613)
"Excellent "
James
The price is NT$2,339
NT$2,610 total
includes taxes & fees
Jan 1 - 2026/1/2
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Perryville Hotel Reviews
Drury Inn & Suites Jackson MO
10/10 Excellent
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- Crown Valley Winery
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- Weingarten Vineyard
- Visit Marble Hill
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- Visit Bloomsdale
- National Shrine of Our Lady of the Miraculous Medal
- Lazy L Safari Park
- Visit Flat River
- Visit Desloge
- Visit Dutchtown