San Francisco

Panama City

A bridge over a body of water with several boats.
A beach with a large driftwood piece, calm water, and a few people in the distance.
A city skyline with a flag, a river, and a park.
A cityscape with a distinctive twisted skyscraper, a busy highway, and surrounding modern buildings.
A cityscape with a rainbow over buildings.

Stay near popular San Francisco attractions

Multiplaza Pacific Mall

9.0/10 (4,497 reviews)
During your trip to Panama City, you can enjoy retail therapy at Multiplaza Pacific Mall. You can enjoy the restaurants while in the area.
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San Francisco Hotel Deals

Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
Avenida Balboa Panama City
The price is NT$6,281 per night from Aug 29 to Aug 30
NT$6,281
NT$6,909 total
Aug 29 - Aug 30
includes taxes & fees
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
8.4/10 Very Good! (1,673 reviews)
"I love this hotel! I would not stay anywhere else! Clean hotel! Great music in the game room, great drinks, beautiful views from our room, lots to do in Panama."

Reviewed on 2026/8/17

Megapolis Hotel Panamá
Aloft by Marriott Panama

Aloft by Marriott Panama

3.5 out of 5
Via Israel & Calle 76 Panama City Panama
The price is NT$4,238 per night from Aug 28 to Aug 29
NT$4,238
NT$4,662 total
Aug 28 - Aug 29
includes taxes & fees
Book a stay at this business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and a nightclub. Our guests praise the helpful staff in our reviews. ...
8.8/10 Excellent! (1,005 reviews)
"Restaurant available.24 hours, didn't like that we need to stop at the desk to punched our parking ticket."

Reviewed on 2026/8/17

Aloft by Marriott Panama
Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall

4 out of 5
Via Israel Multiplaza Pacific Mall Panama City Panama
The price is NT$3,513 per night from Sep 12 to Sep 13
NT$3,513
NT$3,864 total
Sep 12 - Sep 13
includes taxes & fees
Book a stay at this business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in ...
Courtyard by Marriott Panama Multiplaza Mall
JW Marriott Panama

JW Marriott Panama

5 out of 5
Calle Punta Colon, Punta Pacifica Panama City Panama
The price is NT$8,688 per night from Sep 6 to Sep 7
NT$8,688
NT$9,556 total
Sep 6 - Sep 7
includes taxes & fees
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, 4 outdoor pools, and 3 restaurants. Our guests praise the helpful staff in our reviews. Popular ...
9/10 Wonderful! (1,004 reviews)
"The employees were friendly and effective. Also, the gym was well equipped. Given my satisfaction, I plan to return. One thing that will make the hotel more family friendly is to have an indoor play area and ball pit for the small children of guests."

Reviewed on 2026/8/16

JW Marriott Panama
Decapolis Hotel Panama City

Decapolis Hotel Panama City

4 out of 5
Avenida Balboa Con Multicentro Panama City Panama
The price is NT$3,560 per night from Sep 17 to Sep 18
NT$3,560
NT$3,916 total
Sep 17 - Sep 18
includes taxes & fees
Book a stay at this spa hotel in Panama City. Enjoy free breakfast, free WiFi, and free valet parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (1,716 reviews)
"Good environment , stuff etc and the location very close to the malls , and other restaurants"

Reviewed on 2026/8/17

Decapolis Hotel Panama City
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

4 out of 5
Av. Balboa con Calle 53 Panama City Panama
The price is NT$5,187 per night from Aug 30 to Aug 31
NT$5,187
NT$5,706 total
Aug 30 - Aug 31
includes taxes & fees
Book a stay at this spa hotel in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the breakfast and the helpful staff in ...
Las Americas Golden Tower Panama
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in San Francisco

Find the best San Francisco areas and neighborhoods for the activities you enjoy most.
A coastal cityscape with buildings, a hill with a church, and a clear blue sky.

Casco Viejo

Unique features of Casco Viejo include the historic sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

A spiraling skyscraper against a clear blue sky.
Photo by My World
Open Photo by My World

Bella Vista

Bella Vista is highly notable for its popular shops, and you might want to visit top sights like Via Espana and Iglesia del Carmen. See more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina Station.

A city skyline with modern high-rise buildings and a river in the foreground.

El Cangrejo

The abundant dining options and casinos are top of the list for many visitors to El Cangrejo. A stop by Via Espana or Crown Casino might round out your trip.

A cityscape at sunset with tall buildings silhouetted against the sky.

Punta Paitilla

Travelers come to Punta Paitilla for its abundant dining options, and you can see top attractions like Avenida Balboa and Multicentro Panama while you're in town.

A building with three arched windows, a balcony with wrought iron railings, and a tiled roof.

San Felipe

If you're spending some time in San Felipe, Independence Square and Interoceanic Canal Museum are top sights worth seeing.

San Francisco