San Francisco

Panama City

The Bridge of the Americas in summer, Panama City
The Bridge of the Americas in summer, Panama City
This great beach is not far from the Royal Decameron Panama - and it is usually deserted!
The ruins of #Noriega's beach house are part of our "off the beaten path" trip.  The ruins are at Farallon near the Panama Decameron.
La entrada a la Ciudad de Panamá

Popular places to visit


San Francisco Hotel Deals

Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

4 out of 5
Av. Balboa con Calle 53 Panama City Panama
The price is NT$4,487 per night from Feb 9 to Feb 10
NT$4,487
NT$4,936 total
Feb 9 - Feb 10
includes taxes & fees
Book a stay at this spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (1,005 reviews)
Good place to stay for medical services as Paitilla Medical Center, Paitilla Hospital and Royal Center Medical Offices are all within 5 minutes walking. Sushi restaurant on the entry level is excellent.

Reviewed on 2026/1/18

Las Americas Golden Tower Panama
Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel

3.5 out of 5
Italy Avenue, Punta Paitilla Panama City Panama
The price is NT$3,414 per night from Feb 3 to Feb 4
NT$3,414
NT$3,755 total
Feb 3 - Feb 4
includes taxes & fees
Book a stay at this business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in ...
9.2/10 Wonderful! (2,154 reviews)
Everything was top notch. Breakfast was 1st class. Huge variety.

Reviewed on 2026/1/19

Plaza Paitilla Inn Hotel
Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall

4 out of 5
Via Israel Multiplaza Pacific Mall Panama City Panama
The price is NT$2,930 per night from Feb 6 to Feb 7
NT$2,930
NT$3,223 total
Feb 6 - Feb 7
includes taxes & fees
Book a stay at this business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in ...
8.8/10 Excellent! (1,002 reviews)
I will stay there again.

Reviewed on 2026/1/8

Courtyard by Marriott Panama Multiplaza Mall
Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica

4 out of 5
Via Israel y Calle 71, San Francisco Panama City Panama
The price is NT$3,494 per night from Feb 13 to Feb 14
NT$3,494
NT$3,844 total
Feb 13 - Feb 14
includes taxes & fees
Book a stay at this business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,145 reviews)
We enjoyed the pool area, the free buffet style for breakfast with very attentive staff, parking was accessible and service at the front desk by Rafael & Carlos made our stay easy and enjoyable.

Reviewed on 2026/1/17

Ramada Plaza by Wyndham Panama Punta Pacifica
JW Marriott Panama

JW Marriott Panama

5 out of 5
Calle Punta Colon, Punta Pacifica Panama City Panama
Fully refundableReserve now, pay when you stay
The price is NT$8,190 per night from Feb 21 to Feb 22
NT$8,190
NT$9,009 total
Feb 21 - Feb 22
includes taxes & fees
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, 4 outdoor pools, and 3 restaurants. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (1,004 reviews)
The staff was very friendly and the whole property made you feel Safe!

Reviewed on 2026/1/19

JW Marriott Panama
Sheraton Grand Panama

Sheraton Grand Panama

4 out of 5
Via Israel And 77th Street Panama City Panama
The price is NT$4,241 per night from Feb 13 to Feb 14
NT$4,241
NT$4,665 total
Feb 13 - Feb 14
includes taxes & fees
Book a stay at this spa resort in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff and the property condition ...
8.4/10 Very Good! (1,005 reviews)
Great staff

Reviewed on 2026/1/15

Sheraton Grand Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighborhoods around San Francisco

Aerial cityscape skyline of Panama City

Obarrio

4/5(91 area reviews)

Unique features of Obarrio include the casinos and coffeehouses. Make a stop by Calle 50 or Soho City Center while you're exploring the area.

Obarrio
Panama, Panama City

Punta Pacifica

Notable for its seaside views, restaurants, and casinos, Punta Pacifica is a sought-after destination for many travelers visiting Panama City. If you want to see some sights in the area, check out Avenida Balboa or Multiplaza Pacific Mall.

Punta Pacifica
 sunset sky above Panama City -  cityscape panorama view

Punta Paitilla

Travelers come to Punta Paitilla for its abundant dining options, and you can see top attractions like Avenida Balboa and Multicentro Panama while you're in town.

Punta Paitilla
Summer time in Panama City, blue sky and sunny days to enjoy this city. #lifeatexpedia #PanamaCity #travel

Bella Vista

Bella Vista is highly notable for its popular shops, and you might want to visit top sights like Via Espana and Crown Casino. See more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina.

Bella Vista
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Pueblo Nuevo

While Pueblo Nuevo might not have many sights to explore, venturing just a little farther will lead you to top things to see and do like El Dorado Mall and Multiplaza Pacific Mall.

Pueblo Nuevo
Aerial view of the city skyline of Panama City business district

Campo Alegre

4/5(368 area reviews)

If you're spending some time in Campo Alegre, Uruguay Street and Calle 50 are top sights worth seeing.

Campo Alegre


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