San Francisco

Panama City

A bridge over a body of water with several boats.
A beach with a large driftwood piece, calm water, and a few people in the distance.
A city skyline with a flag, a river, and a park.
A cityscape with a distinctive twisted skyscraper, a busy highway, and surrounding modern buildings.
A cityscape with a rainbow over buildings.

Stay near popular San Francisco attractions

Multiplaza Pacific Mall

9.0/10 (4,497 reviews)
During your trip to Panama City, you can enjoy retail therapy at Multiplaza Pacific Mall. You can enjoy the restaurants while in the area.
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San Francisco Hotel Deals

Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
Avenida Balboa Panama City
The price is NT$4,200 per night from Aug 6 to Aug 7
NT$4,200
NT$4,620 total
Aug 6 - Aug 7
includes taxes & fees
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
8.4/10 Very Good! (1,579 reviews)
"The rooftop wasn’t open unfortunately, otherwise this was a stay with an an amazing view of the screw building. The room was huge and it felt safe."

Reviewed on 2026/7/4

Megapolis Hotel Panamá
JW Marriott Panama

JW Marriott Panama

5 out of 5
Calle Punta Colon, Punta Pacifica Panama City Panama
The price is NT$10,510 per night from Jul 31 to Aug 1
NT$10,510
NT$11,561 total
Jul 31 - Aug 1
includes taxes & fees
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, 4 outdoor pools, and 3 restaurants. Our guests praise the helpful staff in our reviews. Popular ...
9/10 Wonderful! (1,000 reviews)
"The Marriott was a beautiful hotel. Helpful staff. Recommended"

Reviewed on 2026/6/29

JW Marriott Panama
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

4 out of 5
Av. Balboa con Calle 53 Panama City Panama
The price is NT$4,217 per night from Jul 29 to Jul 30
NT$4,217
NT$4,639 total
Jul 29 - Jul 30
includes taxes & fees
Book a stay at this spa hotel in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the breakfast and the helpful staff in ...
9/10 Wonderful! (1,049 reviews)
"Great location! Breakfast was good Overall nice stay"

Reviewed on 2026/7/4

Las Americas Golden Tower Panama
Aloft by Marriott Panama

Aloft by Marriott Panama

3.5 out of 5
Via Israel & Calle 76 Panama City Panama
The price is NT$3,968 per night from Jul 20 to Jul 21
NT$3,968
NT$4,364 total
Jul 20 - Jul 21
includes taxes & fees
Book a stay at this business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and a nightclub. Our guests praise the helpful staff in our reviews. ...
8.8/10 Excellent! (1,006 reviews)
"The property was beautiful and comforting. The staff was helping and pleasant. I love it. I definitely will be back there."

Reviewed on 2026/7/4

Aloft by Marriott Panama
Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall

4 out of 5
Via Israel Multiplaza Pacific Mall Panama City Panama
The price is NT$3,503 per night from Jul 25 to Jul 26
NT$3,503
NT$3,853 total
Jul 25 - Jul 26
includes taxes & fees
Book a stay at this business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in ...
9/10 Wonderful! (1,005 reviews)
"Great service Wonderfull location Amenities like swimming pool, little downside."

Reviewed on 2026/7/4

Courtyard by Marriott Panama Multiplaza Mall
Sheraton Grand Panama

Sheraton Grand Panama

4 out of 5
Via Israel And 77th Street Panama City Panama
The price is NT$4,456 per night from Jul 20 to Jul 21
NT$4,456
NT$4,902 total
Jul 20 - Jul 21
includes taxes & fees
Book a stay at this spa resort in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff and the property condition ...
8.6/10 Excellent! (1,003 reviews)
"Bathroom needs some updates, especially the faucets."

Reviewed on 2026/6/19

Sheraton Grand Panama
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in San Francisco

Find the best San Francisco areas and neighborhoods for the activities you enjoy most.
A coastal cityscape with buildings, a hill with a church, and a clear blue sky.

Casco Viejo

Unique features of Casco Viejo include the historic sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

A spiraling skyscraper against a clear blue sky.
Photo by My World
Open Photo by My World

Bella Vista

Bella Vista is highly notable for its popular shops, and you might want to visit top sights like Via Espana and Iglesia del Carmen. See more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina.

A city skyline with modern high-rise buildings and a river in the foreground.

El Cangrejo

The abundant dining options and casinos are top of the list for many visitors to El Cangrejo. A stop by Via Espana or Crown Casino might round out your trip.

A coastal cityscape with high-rise buildings, a calm sea, and a rocky shoreline.

Calidonia

You might enjoy the shopping while in Calidonia. Via Espana is a notable sight, and you can get around town at Estación Lotería or Santo Tomas Station to see more of the city.

A cityscape at sunset with tall buildings silhouetted against the sky.

Punta Paitilla

Travelers come to Punta Paitilla for its abundant dining options, and you can see top attractions like Avenida Balboa and Pacific Center while you're in town.

San Francisco