Find Luxury Hotels in Panama City

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Check availability on Panama City Luxury Hotels

Tonight
Dec 7 - Dec 8
Tomorrow
Dec 8 - Dec 9
Next weekend
Dec 12 - Dec 14
In two weeks
Dec 19 - Dec 21

Top Panama City Luxury Hotels

4 outdoor pools, free cabanas, pool umbrellas
JW Marriott Panama

JW Marriott Panama

5.0 star property
San Francisco
9.0 out of 10, Wonderful, (1005)
"Bedroom was very comfy, also the staff were very on point. I will definitely recommend this hotel and there services, there is so much to do at this hotel."
United States
Sarran
The price is NT$7,844
NT$8,629 total
includes taxes & fees
Jan 4 - 2026/1/5
JW Marriott Panama
Couples treatment rooms, sauna, steam room, body treatments
Bristol Panama, a Registry Collection Hotel

Bristol Panama, a Registry Collection Hotel

5.0 star property
Bella Vista
9.4 out of 10, Exceptional, (1000)
"Love this hotel. Busy area, but hotel and restaurant make up for it."
United States
Allen
The price is NT$5,735
NT$6,309 total
includes taxes & fees
Dec 12 - Dec 13
Bristol Panama, a Registry Collection Hotel
View from property
Waldorf Astoria Panama

Waldorf Astoria Panama

5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1001)
"I loved everything about my stay "
United States
Stephanie
The price is NT$5,610
NT$6,171 total
includes taxes & fees
Dec 17 - Dec 18
Waldorf Astoria Panama
Front of property - evening/night
American Trade Hotel

American Trade Hotel

4.5 star property
Casco Viejo
9.4 out of 10, Exceptional, (600)
"Excellent service and great rooms on a beautiful and historical building"
Canada
Manuel
The price is NT$9,109
NT$10,020 total
includes taxes & fees
Jan 4 - 2026/1/5
American Trade Hotel
Meeting facility
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott

Sortis Hotel, Spa & Casino, Autograph Collection by Marriott

4.5 star property
Bella Vista
8.8 out of 10, Excellent, (1000)
"Clean room nice location "
United States
daniel
The price is NT$4,967
NT$5,464 total
includes taxes & fees
Dec 8 - Dec 9
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
Outdoor pool
Hilton Panama

Hilton Panama

5.0 star property
Bella Vista
8.8 out of 10, Excellent, (1001)
"Great place to stay."
United States
Salvador
The price is NT$5,815
NT$6,397 total
includes taxes & fees
Jan 2 - 2026/1/3
Hilton Panama
View from property
Megapolis Hotel Panamá

Megapolis Hotel Panamá

5.0 star property
San Francisco
8.4 out of 10, Very Good, (1000)
"Great stay! Very safe!"
United States
MARVIN
Megapolis Hotel Panamá
Outdoor pool
Manrey Boutique Hotel

Manrey Boutique Hotel

3.5 star property
Panama City
7.6 out of 10, Good, (255)
"Hotel was closed when we arrived. Had not told us about the closure so we had to scramble to find another hotel"
United States
Anonymous traveler
Manrey Boutique Hotel
View from property
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

4.0 star property
San Francisco
9.0 out of 10, Wonderful, (1003)
"Wonderful stay!"
United States
Martha
The price is NT$5,464
NT$6,010 total
includes taxes & fees
Dec 14 - Dec 15
Las Americas Golden Tower Panama
Terrace/patio
Marriott Panama Hotel

Marriott Panama Hotel

4.0 star property
Panama City
9.0 out of 10, Wonderful, (1000)
"Great breakfast "
United States
Amina
The price is NT$4,428
NT$4,871 total
includes taxes & fees
Dec 12 - Dec 13
Marriott Panama Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Panama City Hotel Reviews

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

10/10 Excellent
"Very good breakfast and very nice hotel and close to lots of restaurants "
Michele 4-night trip
Posted 1 day ago
Hotel Riu Plaza Panama

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Frequently asked questions

Are you searching for the perfect hotel for your luxury getaway to Panama City?
Arrange a flight into Panama City (PAC-Marcos A. Gelabert Intl.) Airport or Balboa (BLB-Panama Pacifico Intl.) Airport, and then treat yourself to a stay at one of 23 luxurious hotels. Known for its casinos and shopping, Panama City also has some interesting things to see and do including Albrook Shopping Mall, so you may want to take in the local sights during your visit.
What's the best luxury accommodation in Panama City?
Hotel Riu Plaza Panama is a luxury hotel with 3 restaurants and valet parking, and it's a popular choice for Expedia travelers looking for an elegant place to stay. Megapolis Hotel Panamá and W Panama are other upscale choices for your trip.
How many luxury hotels will I be able to find in Panama City?
Lie in the lap of luxury during your getaway to Panama City in one of Expedia's 23 luxury hotels.
When can I expect good weather in Panama City?
Planning for the weather is a good way to make your trip to Panama City relaxing and enjoyable, especially when you're splurging. The hottest months are usually March and April with an average temp of 80°F, while the coldest months are January and February with an average of 79°F. The rainiest months in Panama City are July, August, June, and November, with each month seeing an average of 15 inches of rainfall.
What's there to see and do in Panama City?
Experience Panama City and visit Albrook Shopping Mall, Via Espana, and Iglesia del Carmen. If you have spare time during your trip, you might want to make a stop at Uruguay Street and Crown Casino.
How can I get around Panama City?
It's easier to get around town in style when you know your options. You can walk to nearby metro stations including Iglesia del Carmen Station, Vía Argentina, and Santo Tomas Station. If you want to venture outside of the area, hop on a train at Panama City Passenger Station.