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Our top choices for Northwest Alabama hotels

A hotel lobby with a seating area, a reception desk, and a check-in counter.

1. Residence Inn Florence Marriott

East Florence

Nathan

NT$4,225 total

includes taxes & fees

Nov 22 - Nov 23

A spacious lobby with a blue sofa, a wooden table, and chairs. There is a TV on a stand and a painting on the wall.

2. Hampton Inn & Suites Florence-Downtown

Florence

Heather

NT$6,178 total

includes taxes & fees

Nov 29 - Nov 30

A modern kitchen with wooden cabinets, a countertop with various appliances, and a view of the outdoors.

3. Holiday Inn Express Hotel & Suites FLORENCE NORTHEAST by IHG

Florence

LaRhonda

NT$3,961 total

includes taxes & fees

Nov 8 - Nov 9

An indoor swimming pool with tiled steps and a sunlit room with chairs and a window.

4. Comfort Suites Florence Shoals Area

Florence

Elizabeth

NT$3,226 total

includes taxes & fees

Nov 15 - Nov 16

A hotel room with a bed, a desk, a chair, a mirror, a painting, and a nightstand with a lamp.

5. Days Inn by Wyndham Muscle Shoals Florence

Muscle Shoals

Shana

NT$2,575 total

includes taxes & fees

Nov 17 - Nov 18

A spacious lobby with a reception desk, seating area, and a balcony.

6. Best Western Plus Tuscumbia Muscle Shoals Hotel and Suites

Tuscumbia

Colin

NT$3,719 total

includes taxes & fees

Nov 15 - Nov 16

A hotel room with a bed, a desk with chairs, a small kitchenette, and a TV.

7. Microtel Inn & Suites by Wyndham Tuscumbia/Muscle Shoals

Tuscumbia

Brian

NT$2,290 total

includes taxes & fees

Nov 8 - Nov 9

A hotel with a large pool area, a water tower, and a dome structure.

8. Renaissance Shoals Resort & Spa

East Florence

Christina

NT$10,148 total

includes taxes & fees

Nov 23 - Nov 24

A bedroom with a brick wall, a dark blue headboard, and patterned pillows.

9. The Stricklin Hotel

Florence

Dana

NT$5,797 total

includes taxes & fees

Nov 8 - Nov 9

A spacious interior with a central staircase, a chandelier, and a view to the outdoors.

10. Spark by Hilton Tuscumbia Muscle Shoals

Tuscumbia

Patrick

NT$3,033 total

includes taxes & fees

Nov 11 - Nov 12

A spacious lobby with seating areas, a reception desk, and large windows.

11. Clarion Inn Sheffield Muscle Shoals

Sheffield

Billy

NT$2,818 total

includes taxes & fees

Dec 1 - Dec 2

A modern hotel room with a large bed, a desk, a chair, a window with a view, and a wall-mounted lamp.

12. Hampton Inn Florence Midtown near University of North Alabama

Florence

calvin

NT$4,919 total

includes taxes & fees

Nov 15 - Nov 16

A spacious lounge with a fireplace, leather sofas, and a bar area.

13. GunRunner Boutique Hotel

Florence

John M

NT$6,933 total

includes taxes & fees

Nov 8 - Nov 9

A hotel room with a bed, a desk with a lamp, a TV, a sofa, and a view of greenery outside.

14. Comfort Inn & Suites Tuscumbia - Muscle Shoals

Tuscumbia

David

NT$3,948 total

includes taxes & fees

Nov 22 - Nov 23

A modern hotel room with a large bed, a separate sitting area, a bathtub, and a view of the outdoors.

15. Red Roof Inn Muscle Shoals

Muscle Shoals

Keith

NT$2,366 total

includes taxes & fees

Nov 5 - Nov 6

A spacious living area with a staircase, a flat-screen TV, and a seating area with a coffee table.

16. Best Western Plus Russellville Hotel & Suites

Russellville

Dennis

NT$3,894 total

includes taxes & fees

Nov 17 - Nov 18

A blue mat with the text "Baymont Inn & Suites" on a wooden floor.

17. Baymont by Wyndham Florence/Muscle Shoals

Florence

Alan

NT$2,565 total

includes taxes & fees

Nov 22 - Nov 23

A hotel room with a bed, a desk, a chair, a nightstand, a lamp, a painting of a sunset, and a bathroom with a mirror and sink.

18. Days Inn by Wyndham Moulton

Moulton

Debra

NT$2,300 total

includes taxes & fees

Nov 8 - Nov 9

A reception area with a counter, a television, and a door labeled "EMPLOYEES ONLY".

19. Budget Inn & Suites

East Florence

Nazul

NT$2,143 total

includes taxes & fees

Nov 17 - Nov 18

A reception area with a stone wall, a reception desk, and a door leading outside.

20. Econo Lodge Russellville

Russellville

Mark

NT$2,516 total

includes taxes & fees

Nov 15 - Nov 16

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Vacation Rentals in Northwest Alabama

Cottage

A cozy cabin interior with a stone fireplace, wooden walls, a red sofa, and a patterned rug.

Pet-friendly Haleyville Cabin Rental w/ Kayaks!

Haleyville

"My wife and I were in town for family business. We have many family members in the region, and we wanted to stay far off the grid. I’m glad we did. No phone, no cable, no nothing. Absolutely fantastic! We plan to bring our children on the next trip in about 8 months. This place is #1 on the list for my wife and I. I have stayed in most states and countries, but this by far is the best stay in quite some time. We are coming back. If you want to make an offer to sell, let me know. "

Cottage

A living room with a ceiling fan, a television, a leather sofa, and a wooden cabinet.

Killen Vacation Rental ~ 4 Mi to Wilson Lake!

Killen

"Great place to stay. "

Cottage

A covered patio with wicker furniture, a brick wall, and a view of the garden.

Charming Florence Getaway w/ Fireplace & Grill!

Florence

"The house was beautiful, clean, spacious, and very comfortable. It had all the amenities you could want and need. It was a quiet and nice neighborhood and close to dining and shopping. The owner kept in touch with us the entire stay and was very kind. We will definitely stay there again!"

Cottage

A modern kitchen with granite countertops, a stone backsplash, a built-in oven, and a large window overlooking a garden.

Expansive Florence Home ~ 6 Mi to Downtown!

Florence

"Our family totally loved staying here - close where we needed to be and we were so comfortable - especially with 3 bathrooms for 3 bedrooms! Loved it!"

Cottage

A modern living room with a blue leather sofa, two brown leather armchairs, a small round table, and a staircase leading to the upper floor.

7 Mi to Tennessee River: Home w/ Patio in Florence

Florence

"We loved the place huge rooms we had 10 people and had plenty of room .We would stay again but floors needed sweep and mopped but overall it was a great place ."

Cottage

A sunroom with a glass door, a ceiling fan, a hanging chair, and a view of the lake.

Waterfront Bliss: Wheeler Lake Retreat w/ Dock!

Athens

"Enjoyed your home"

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Stay near popular Northwest Alabama attractions

Dismals Canyon

9.0/10 (35 reviews)

Commune with nature and explore the great outdoors at Dismals Canyon during your travels in Phil Campbell. While you're in the area, wander around the natural setting.

See properties

Learn more about Northwest Alabama

Explore the family-friendly area of Northwest Alabama—live music, entertainment choices, and sights from Dismals Canyon to Cane Creek Canyon Nature Preserve.

See all hotels in Northwest Alabama

A waterfall cascading over rocks in a forested area.

Top Northwest Alabama Hotel Reviews

Days Inn by Wyndham Muscle Shoals Florence

8/10 Good

"The staff was amazing and the room was very clean. And breakfast was really good"

Best Western Plus Tuscumbia Muscle Shoals Hotel and Suites

8/10 Good

"Heating/air system was quieter than most motels. Adrian at the front desk was really nice. The coffee pots are difficult to use, you have to pump the coffee. The brakfast was adequate but the scrambled aggs were awful and the dining room was almosr empty but they ran out of bacon and it wasn't refilled quickly if at all. The little tiny bottles of shampoo and conditioner were barely enough for one person. Dispensers in the showere on the wall which most places have would be much better. We were only there for one night so it was convenient and adequate and reasonable priced."

Hampton Inn & Suites Florence-Downtown

10/10 Excellent

"This is the second time I stayed at this hotel, and I like it. I like the staff, the amenities, the location, and the convenience. I did pay a lot more this time for a room, though, and when I asked about it, I was told that it was because it was on Halloween night. Seems a little uncouth to raise the price of the room that much because it was Halloween."

Microtel Inn & Suites by Wyndham Tuscumbia/Muscle Shoals

8/10 Good

"The staff were nice and helpful. The breakfast was good with scrambled eggs and sausage available. The room was mostly clean except the carpet was pretty stained. The carpet in hallway was in need of attention also. Overall, I would stay again."